Basic Information

Insect: Drosophila kanapiae
Gene Symbol: PRDM1
Assembly: GCA_008042475.1
Location: VNJM01000412.1:215530-220335[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 2.7e-05 0.0022 18.4 2.5 1 23 923 945 923 945 0.99

2 5 8.2e-06 0.00065 20.1 5.1 1 23 951 973 951 973 0.98

3 5 1.7e-06 0.00014 22.2 4.3 1 23 979 1001 979 1001 0.98

4 5 0.00057 0.045 14.3 2.4 1 23 1007 1029 1007 1029 0.97

5 5 9.6e-05 0.0077 16.7 0.1 1 22 1035 1056 1035 1056 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	2.7e-05	0.0022	18.4	2.5	1	23	923	945	923	945	0.99
2	5	8.2e-06	0.00065	20.1	5.1	1	23	951	973	951	973	0.98
3	5	1.7e-06	0.00014	22.2	4.3	1	23	979	1001	979	1001	0.98
4	5	0.00057	0.045	14.3	2.4	1	23	1007	1029	1007	1029	0.97
5	5	9.6e-05	0.0077	16.7	0.1	1	22	1035	1056	1035	1056	0.96

Sequence Information

Coding Sequence: ATGCACGGACACCACCACAATCATCCACAGAATccacaggagcagcagcagccgggagCCATCATGAAGCTGGGAAGCTCCTCTGGCCAGCCACACCATCCCGCCCACAGCCATCCACAGCTCAACCATTccccgcatccgcatccgcatacCCATGTCCAGCCACACCCGCATTCACACCCACATCCGCATCCCAACCACCAGAATGTGCACCCGCATCCGCACCACAAGCTGTCGGCGAGAAGGGCGCGCAGCCGCAGTCGAAGTCGCAGTCCGACGCCGGATGGCAGCCAGGACTACGATGTGACCAGGATGCGGGAGGAGGACTTCGAGCGGCTGGCCGTCTATCTGGTGCCGGACGTGCAGGCGGAGCGGGGACTGCCCAATCGAGCGGACAAGACGCTGCCGCGCAGCCTCACGCTCAAGTCATCCATGGTCTACTCAACGCCAAATGTTAAGACTGAAGGAGTTTGGAGCAGCGGGGTCATCCCACGTGGCACTCGCTTCGGCCCATTCGAAGGCATTCCAACTTCAAACTATCCCAATGATAAGAATAAGGCGCGTTATTTCTGGCGGGTGCAGGGAACACGCCACATAACCTACGGGAATATTAAGATCTTCAAGGACGACGACTACTACTATCTGGACGGATCGGATCGCTCGCAGTCCAACTGGATGCGCTACGTGGCCTCCGCCTACAGTCTGTCCGTGATGAACCTGGTGGCGTGCCAGCACCAGGAGAACATCTACTTCTACACGACCCGCGACATCCTGCCCAACGAGGAGCTGATGGTGTGGTACTGCAAGGACTTCGCCAGCCGCCTCGGCTACGACGTCGATCCCGAGACGACCATCTTTGGCGCCTGCAAGCAGGCTGTcgaggccgaggaggaggtgatggacgaggaggaggaggaggcggagcaggaggaggatggCGAAGCGGGAGCTGAGGGTGGCAAGCGTCGCTACTCGATGCCTGCCCCGGAAATTCCAGCCGAGGTGGCAGTGAGTCACATTACCTACGTGATGGGTCTGCATCTGCCGGTGGGAGCGGCGAACGGTGGACCGGCAAGTGGTTCCAcctcgccgccgccacctaCGCCCGCCGGCGGCCAGTGCTGCCGGAGATCGAGCCCACCCGCCCATGTCAGCACCACCTCCTGCAATGCCCACCATCCGCACATCCAGCATGCCGGTCGCCACGCCTCGGTGATCATCGGCCAGGATCGCTCGCCGCTGACCAGCAGCAGTGACAAGGACACGGCGGGATCGCCGCTGTCCGGCCTTGACCACCAGCTGACGCCGCAGGACGGCAGCGTGAGATCGGTCCGCTCGGACGAGGGCTACCACAGCAATGAGTGCCACGAAGATGGCCTCACGCCGCCCGAGGATTCCAGCGACAGCGAGAGCGAGCACAACTACGTGCTGGACTGCTCCAAGAAGGCCATCGCCCCCAAGGAGACGGTTATTGCCCAGGCGCAGAAGCCGAGCAGCTCGCCGCCGGCAGTGGTCATGGCCAATCCcatcagcaccaccaccaccagcagtaGTATTAGCCACGGCGCGTCCACGGCCCCGGCCTCCTGTGAGCCGGACAAGAACGAGTATAGGAAGTTCAAGGTGAAGATGCCGCTGAAGTACGAGTTCAAGAACAAGAGCTGTGTGAAGCAGGAGCCCAGCCTGAAGGAGGTGGACCACGAGATGTCGCTGCCGCAccacgaggaggaggaggagcacccTATGCACCAGGAGCCCGACTCCATCTGCCCCTCGACCACCACGCATTTGGGCGATGAACATCTCATGATTATGGAGAGGGAACGcgaaagggaaagggaacgggaacgggaacgggatcgggaacgggagcgggatCGGGAGCCATCCAACCAGCAGCCCGCCTCCTCCACGGTAATCGTTCTGGAACACAACTCCGGAGGCCAGACCCGCACCATAGTACCGCTGAGCAAACCCTACTACGAACCGGATCCGCCGGGCGAGCGCTATGTGCGCTTTGGCCAGCCCAGCTCCAGCATCCTGGAGACGATCCTCACCAGCCAGCATCGCCTggaggcagcggcggcggcagccaatGCCTGTCGCCAGGCCAACGCAGCCACGCCGCCACCCACTTCGCCCACGGAGATGGCCTACAGCTACAAGAAGTCCCAGCGCTACGGCAATGCCGTCAGTCCAGACAGCAGCTCCAATCTGGGCCAGAgtgccgagcagcagcagcagggagtgGGCGTGGTTGTGGGCGGCGACCAGGAGATGACCCGCGGCACTTTGATCAAAGGCGAGtgctcgccgccgccgccgagtcACCATCACCACAACGTGATCTTCTCGCCCTCCAGGCATCCGGCCTACCTGGGCGCCGGAGAGGCGGGCGGTCACTCGCCGAGTCCCGGCTATCCTGGATATCCGCACTACGGAGCCGCAGCCACCTCCACCTTCCACTCGCCGCCGCACAGCTCACATTCTCCCTTCGACCGGCAGTCGAATGCCTCGAGCGGAGCGGGCTCCGCCTCCAACTTGCATTTGCTGCAGAGCAGCACCCAGATGCTGAACCATCCGCTGATGCAGCCGCTCACCCCGCTGCAGCGCCTCTCCCCGCTCCGGATCTCGCCGCCGAGCAGTCTGAGTCCGGACGGCAACTCCTGCCCCAGGAGCGGCAGTCCGCTGAGTCCCAACTCCCTGGCCTCCCGTGGCTACCGGTCTCTACCGTATCCGCTGAAGAAGAAGGATGGAAAGATGCACTACGAGTGCAATGTGTGCTGCAAGACCTTCGGCCAGTTGAGCAACCTGAAGGTCCACCTGCGGACGCACTCGGGCGAAAGGCCCTTCAAGTGCAACGTGTGCACCAAGAGCTTCACCCAGCTGGCGCACCTGCAGAAGCACCACCTGGTGCACACCGGCGAGAAGCCGCATCAATGCGACATCTGCAAGAAGCGTTTCTCGAGCACCTCCAACCTGAAGACGCATCTCCGGCTGCACAGCGGCCAGAAGCCGTACGCCTGCGATCTCTGCCCGCAGAAGTTCACCCAGTTCGTGCATCTCAAGCTGCACAAGCGCCTGCACACGAACGACCGGCCGTATGTGTGCCAGGGATGCGACAAGAAGTACATCAGTGCGTCGGGCCTGAGGACGCACTGGAAGACCACCAGCTGCAAGCCCAACAACCTGGAAGAGGAGCTGGccatggcggcggcagccaccTCCGAGTGTTTGGACAAGGACCACCCCGAACCGGACTCCCGCGAGGCATacgagcaactgcagcagcacatGCATCCCGCTGTGCATCCCGGCCTGCGTCACTTGTCCGGTAGTGGCGGACAATCTCCACCCCGCCTTATTCCGCTGGGCAACCACATGgcgccccagcagcagcaccagcaacagcagcaacacccgCAGCAGGGAGTGCCACCTCCGCCGCATTTGCTGATGGGCCAGCATCCGGCTCCCATGCTCCTGACCACCGCCAGCCAGCTGCCTCCGCCGCTGCCCTCGCACCACCAACAGTCCTCGCCCAGCCGCCTCCTCCAGCACGCCCATCCCCATgcactccagctccagcagcagcagcagcaacagcactcGCCCAAGGGCCTGAAGTCCCTGCCGGAGTCGGGAGTGTATCTGCACGGGCCGCATGTGCAGGCGCAGGAGAGCAGGCCCTCGGTCATCGAGTCCTCCAACCAGCCCATGATCATCGAGTGCACGTAG
Protein Sequence: MHGHHHNHPQNPQEQQQPGAIMKLGSSSGQPHHPAHSHPQLNHSPHPHPHTHVQPHPHSHPHPHPNHQNVHPHPHHKLSARRARSRSRSRSPTPDGSQDYDVTRMREEDFERLAVYLVPDVQAERGLPNRADKTLPRSLTLKSSMVYSTPNVKTEGVWSSGVIPRGTRFGPFEGIPTSNYPNDKNKARYFWRVQGTRHITYGNIKIFKDDDYYYLDGSDRSQSNWMRYVASAYSLSVMNLVACQHQENIYFYTTRDILPNEELMVWYCKDFASRLGYDVDPETTIFGACKQAVEAEEEVMDEEEEEAEQEEDGEAGAEGGKRRYSMPAPEIPAEVAVSHITYVMGLHLPVGAANGGPASGSTSPPPPTPAGGQCCRRSSPPAHVSTTSCNAHHPHIQHAGRHASVIIGQDRSPLTSSSDKDTAGSPLSGLDHQLTPQDGSVRSVRSDEGYHSNECHEDGLTPPEDSSDSESEHNYVLDCSKKAIAPKETVIAQAQKPSSSPPAVVMANPISTTTTSSSISHGASTAPASCEPDKNEYRKFKVKMPLKYEFKNKSCVKQEPSLKEVDHEMSLPHHEEEEEHPMHQEPDSICPSTTTHLGDEHLMIMERERERERERERERDRERERDREPSNQQPASSTVIVLEHNSGGQTRTIVPLSKPYYEPDPPGERYVRFGQPSSSILETILTSQHRLEAAAAAANACRQANAATPPPTSPTEMAYSYKKSQRYGNAVSPDSSSNLGQSAEQQQQGVGVVVGGDQEMTRGTLIKGECSPPPPSHHHHNVIFSPSRHPAYLGAGEAGGHSPSPGYPGYPHYGAAATSTFHSPPHSSHSPFDRQSNASSGAGSASNLHLLQSSTQMLNHPLMQPLTPLQRLSPLRISPPSSLSPDGNSCPRSGSPLSPNSLASRGYRSLPYPLKKKDGKMHYECNVCCKTFGQLSNLKVHLRTHSGERPFKCNVCTKSFTQLAHLQKHHLVHTGEKPHQCDICKKRFSSTSNLKTHLRLHSGQKPYACDLCPQKFTQFVHLKLHKRLHTNDRPYVCQGCDKKYISASGLRTHWKTTSCKPNNLEEELAMAAAATSECLDKDHPEPDSREAYEQLQQHMHPAVHPGLRHLSGSGGQSPPRLIPLGNHMAPQQQHQQQQQHPQQGVPPPPHLLMGQHPAPMLLTTASQLPPPLPSHHQQSSPSRLLQHAHPHALQLQQQQQQQHSPKGLKSLPESGVYLHGPHVQAQESRPSVIESSNQPMIIECT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00609398;
90% Identity: iTF_00606569;
80% Identity: -