Dkan004317.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila kanapiae
Gene Symbol
HIVEP2
Assembly
GCA_008042475.1
Location
VNJM01003527.1:802078-810557[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 0.00027 0.021 15.3 0.2 1 23 190 212 190 212 0.98
2 8 0.00027 0.021 15.3 2.9 1 21 218 238 218 242 0.89
3 8 0.032 2.6 8.7 0.1 1 19 867 885 867 888 0.93
4 8 2.4e-06 0.00019 21.7 2.0 1 23 1603 1625 1603 1625 0.99
5 8 1e-05 0.00081 19.8 5.3 1 23 1631 1655 1631 1655 0.92
6 8 0.00035 0.028 14.9 2.3 2 23 2154 2175 2154 2175 0.97
7 8 0.00069 0.055 14.0 1.2 1 23 2181 2205 2181 2205 0.91
8 8 0.0022 0.18 12.4 2.7 1 23 2226 2250 2226 2250 0.92

Sequence Information

Coding Sequence
atgGAAAATGCAAGCACCACAACGGCCAAGCATTACAAGACAGCAGGCAAACAGTACAAGACCAATAAAAAGTTCAAGAGATTGGCCAGCACCACCGAGGTGGAGAGCGGGAGTGCAACGGCCAATGGTGGACCTTTAACCGATGCCGGGATGCGCACCACATCGCTGTCCTCAAATAGCTCACTGTCACCTCCGCCGATGGTCAGCAATGGTCACCACTTgacccaacagcagcagcagcagcagcagcaacaaagtaGACCGCCTGCCATTACCACCACACATGAATTCAGTGCCAATTTTGTAAATAGCAATCATGTCAATGCCATTGGTCAGGAGGAGAGCAATAGCCACAAGGTAGCGCTGAATGCGAGAACGCGAATGCCGCTGACAAACAGCAGCGGCACAAGcaccagcagtagcagtaacTATGCAGCGAATGCCACATTGACGCCAGCAACCTTtgcccagcaccagcaactGACGCAGCCAacggcaggaggagcagggaTAGCAGGCGGAGGCGGTATACCAGGCGGAGGAGCGGTCGGTGAGAAAGCCGGACGCTATGTCTGCCCATACTGCAATCTGATCTGTGCCAAGCCCTCGGTGCTGGAGAAGCATATACGCGCCCACACCAACGAGCGGCCATATCCCTGTGACACCTGCGGCATTGCCTTTAAGACCAAGAGCAATCTGTACAAGCACTGTCGCTCCCGGTCGCATGCGGCCAGAGCCAGGGGCTTGGAGGTGCCAGCCGATGCGGACGATGGTCTGTCCGATCAGGATGCTGAGCTGAGCAACAGTAGCTCCGAATTGCCAAGTCGCGCTGGTTCGCCCTACGATGAGCCAATGAGCTCGCCCACACCCTCACCTTCCACGCTGTCGGCGACAAAGAGCGCCTACATTCAGCaaccgccgccactgccacagCACATGCAACAATTGCCGCTGGGCTCGCCGGCAGCTGGCACCTTGCCGCCCACAACATCGGACCAACTGCATTCGGCCACGGCCCAGCATCGTCCGTCTATAGATTACAAGCCATATAAGCCCAAGTTCCACAATGCCTCCTTGTATGCCCCAGGCAGTAGcaaggagcaacagcaacagcagcagcaacagttgcagttgcaacagcagcagcagcagcaacagcaacaccagcagctgGCCCAGCAGAAGCTATCCATTCAGCTGCCTTTGgtacagcagcagccatcgcTCACACATCCCACGCTTTCGCCCAGCACccagatgaagatgaagaacCACATCAACTCGCACCAGCTCcagatgcagctgcagcatcaATTGCATGCCCAGCAAAGCCTGTTGGCCTCCATGCCGCCAGTGCCGCCAGCGGGTGTCTATTATCTGGGACAGTCACCCTATTATAATCCCGATCCAGCGGCCATTCAGCACAGTGCTTTGGTCTTCCACCAGTTTCAACTGCAACAGAtgcacctgcagcagcagcagcagcaacagctacagcagcaacagcagcagcaacaacagcagctacagcaacagcagcagcaacactctCCTTTGGTAAAGGCACCTCAACAGCCAGCAAGTCTTCCGCCTCAACAGCTGGTGCGAGCCAATAGTCAGGTTTCCAATGTGACACCAgcacctgccacgcccacgcctgccgccgccgccaatctCAGCAGTTTTGCCAGCTCCAGCGGCAGCATGCAAGTTAATGTGGCCAAGGTTCAGGAGCACATATCCAAGTTGATCTCACAAAACGAGGCTATAGTGGAGAACAAGGAGATATTGCTGCAGAAGAAGTACCCCAAGCAGCTGAATCGTTCCCGCAGCTTCAACAATGCCAAtagcaacagtagcagcagcaacaatgccgCCAATGCGGCGGCTGCGTTGCATGCGAACAGTAACAATAGTAGCCACAATCTGAGTGCACAGATGCCGGAGCGGGAGACTAAGGTGAATTTGGCACAGGCCATAGtccagaaacagcagcagcagcagcagcagcaacaacatcaacttcaacagcagcaactccagcagcagcaacagcaactccaACAGCAATCGGCGCTCGAACAACAGCACTTTATGTATGCActtcagcaacagcagcagcagcagcaagaaagCCAGCAGCCACAACCGCAACTCCTGGAGCCGCCCAATGGTTTAACCAAGCGGAATAGCTACAAGCCACCACCTCAAGCAATGACCACCACCACGCCCGtcaagcagcaacagcaacagcagcagcagcaattgccgccgccaccttcGCCGCTGCCCATGCAGACGATGCAATATCGCCAGGATCCTGCAACGCCAGTGGCCAAAATGGAGCAACCCGCCACCGCTGTCCATGTGATGCCTTTGAACCTGTcagcaaagccaaagcccgCTGTGATTACGGTGCCCGTGAGCTCATTGTCCAACAGTTTAGTGCCTGCCACATCCACCAGTTCTTCGGGGGCTGCCGCGGGCAGCACGAAGGCGGCATCAGCGCCTGGACAagttaataattcaattattaagaATCTGCTGCTGAATGCCCGTGGATTGGCCGTGCCCATTGGCGAGGGCGAGGATGCCGTCTACTCGTGTCCAATCTGTGCCAGCGAATTCCGCAGTGCGGACGACTTGAAGCTGCACAACAGCACCTACTGCCAGGATGCGAGCTCCAGTGCACCGATGAGTCCCGCTTCCAGTCCCTTCCGCTCGAACTCGATCTCATTGAGTTTGCCGGAGCTGAAGAGTCATATGGCGAACTCGAAGAATCCGTTGTCGCTGGCCAAGCTGGCCTGGTCACAGCTGGAGACCAAGCGGAGTAGTTTGGTGGCAAGTTGCCTGAATGCGGCCCAGACGCCGGCAAGGACGTCCACAGTGACAGCTGCCTTGACAAGTGCTCCAGTTACAGCTCCAGCGCCTGCTCCCGCtacggctcctgctcctgctcctgctcccgctcctgctccagctcctgctccagctccagcgccGGCTCCCGCGCAGCTGCCTCTGGAAGGACTGCGCTTTGTGGACGCACCACTGCCTTCGCCTGGGCCCCTGCTTGGCAAGACGCCCTTGGTGGACTATGCCCAGCAGAATGCGCCGCGGAAGCCTCAGCAGGACTCGGTGGTGATTACAAAAATGCACGAAGATCGCCTATTTGCCATCTTGGATTTGGAGGCACAGCCCGCCAAGCGGGTGAAGACCAGCGATTCCACGCAAGCCTTCTCCTTTCCCTTTaccaaccacaacaacaacaatagcgcCCAGGATGCCCAGCCCGTCAAGGAGGAGCGCCTGCACAGGTTCACCTCATCGGGTGGATCAATGATTCCCATATCCGAGTGCCCGGACTTGGAGAACAGTCCCAAGATGATAAGGACACCCCTTCTATCCGGTGGCAGCTTCCAGGATGTGTCGGTCAAGGTAATCGAGGAGCGAGGATCGAGCAAGGAACGCAAACTGATGGCCCTGGTCAGTGGGAGTGGCCTCCTCGCCGCCAATGCCGGACCACAGCATTTTCAGTTTCCGCCCATCAATTCGATAACTGCCTTCAATCCGCTGACATTGCCGCTGACAATGAGTGGAGCTGGCGGCGGTGATAAGTCCACGCCCGTTACGCCCATTCCCTATGTTCCAGGTATACCGGGACCAGGATCTCTTACCCCGCAGATGCCGCtattgccaccgccgccccaGCAACTGCAGTTGCCTGTTCCGTCGGGACGCGGCCGTAGCCCAAATCGCAAGCAACCCAGTCCGCTGCTGATGGCAGCGGGAGCTGGTGATCTGAAGGCTCTGTCGCCGTTTGGCGGTGTCCAGAATTTGCCCAGCGAATTTAGTCGCCAGCCACCGACGCCAGCGCAGCGCCAGGCGTTGCAGTGGAACAGCAAGGAGGCAACGCCAAAGAAGGCGGCGGCGCCCTTCAACTTCCTCCGTATGGCGGATAATGTAAAGACCGCACCGGAACCGGAAGTACGCCACTTCAACCTGGACAATGTGATTGGgggaaagcagcagcagcagcagcaggagtcgCCACTAACTCCACTCCACGTGGAAACCCCCAATGGTAATGCCACGGAGGAAGCCAGTCCCAGTACCTCAGCGAAATCAAAGTTCCTGCGACCCACCAGCTTGCCCTTGAAACCGGGAACCTTTACGCCCAAGCGTCATCATGGAATCACGCCAACAGCAAACACACTGCCACTGATCTCGCCGGAGACACCGCGACCCTCCAAGTCCTGTGTTCAACTCTACCTCAACGGGCATGCTTACACCTATCTGGGGCTCAAGTGCAGCACCAAGATGTTCTACTGTACGGTGAACTGTCCGCAGCCCTCGTATGTGGCGGGCATGCACAAGCTATCCATGTACAGTGTTTGGCAGGTGTGCGAGGAGAATCAACCGCATCCCCTTGGATTCAAGCTGAAGAAGGTGATGTCGCTGTATGACTCCCGTCAGAGGATGCTGGGTAATGGCAGTTCCACTGCCATGGCTGGATCGGGGAAGCTAAGCTACAATGTGGTCTCCTCACAGCAAACGGTGAGCTCCACGTCCACGTTGGTCAGCGCCAGTGCCAGTGTATTCTATCAGAATCAGCTCAAGACACCGCCAGCTGTGGTTTCTGTGTTGAGCGAGGCCAATGTGGCGGCCAAGGcgaacgaggaggaggaagcggaggcggcggcacagGCCAAGAAGCTGGAGACCAGTCCCTCAGGACAACCTTTGGTTGGTGGCTATGAGTCTCATGAGGATTACACCTATATCCGGGGACGGGGACGCGGCCGATATGTGTGCTCCGAGTGTGGCATACGCTGCAAGAAGCCATCGATGCTGAAAAAGCACATACGCACCCACACGGACGTGAGGCCCTTTACCTGCAGTCACTGCAATTTCAGCTTCAAGACCAAGGGCAATCTGACCAAGCACATGCAGTCCAAGACGCACTTCAAGAAATGCATCGAACTGGGCATTAACCCGGGACCCATGCCCGCCGATGGCGAGTTCCTGGATGTGGACATGGACTTTGATCAGCAGTCATCGACCTCTGCGGGCGGACGCACCTCCTCCATGGCGGGCGAGTCCGATTCGGATGATTACAGTGACAATGAATCGGAGAGTAGTGACACCGACGAGTCCAAGTCCCGTTTGAAGGAACACGAGGCAGCCCGATGCCTGCTGTCGCTTTCGATGACGCCGCCCATTCCACAGAGTGTGTCGCCTTATCCACAACACCTGCAGGACACACCTCTGCCTGCCGCCAGTCCTGCCAACAGCATTGGTTCTTCCGGCTCCTTGCCCAAACGTTTGGTTTGCTCCTTTACCTCACCAAAGCCCCCCTTCGACTATCAGAAGCAGGAACAGTATTATTCCAATCCGGAGGAGTCCAAGCCGAAGCGCAGTGTGGCCAGCGAGGAAAGCGCTCCCATGGATCTGACCAAGCCGCGTGGTTTGATGATGTCTTCCGCTGTGTCGCCAGTGCCACCGTCGCCAGTGCCGCCGCCCAAATCGCAGGCCCAGCAAATGCACGATGTGATCTTTGGCAGTTCGGGCAATGAGAGCGGCTTCATGAAGACTCTGATTTCGGTGTCGGACAAGGTGCGAATTTCCGCTGAAATGGAGGAACTGGCCAAGCACGAGGCCAGGTCCGAGGTCCAGGATGTCCTGCTGCAGACGTACATCAAGGAGCAGGCGCGACTCAATGCCAAGCGAAAGTTAAGTCAGCTGAGTGACACATATCTCATCAATACTTTGATCTCCAAGGCGGCGGCCACGGCAGGCACGGCGACCACGGTGATGAGTAGCAGTGGTAGCAGCCTATTGACCACAGGCAGTCGACCCATTATGACCATTAATGAGGTGCCCAGCATCGAAGTGCATGAGGTGAAGACGCCCGAGGCTGTGGAATTGCCAGCAATTCCTCCAGCGACACCTACAGCTATACCTACAGgaacagctacagctacaggaACCCCTACAGCTACACCCACACCTACAGCTACAGGTACAGCCACAACCACTCCCACACCCACTCCGATTACCGTCAAGATGGTGCAGGATGAGAGCGACGAATCGGACCAGGAGAAGCCCTTGGCAGAGCCACATAATGCCAATCTGCCAGCTGCAGTGCAGCAAAAGGATGCCAATGATTTTACCGGGGTCCTTGGACAACCGCCACATTCACAGGCcacaggaggagcagctgctgccgccgccgcttctgctgctgctgtagccaCGTCAACATCTGCTTCCGTGGCCATACCCACCACCTCTAACAACACACAACCCACGCAGCGAACTGTAATCGTTGGTGAGGATGGCTTCAAGAGCTCCACGCCCaccagtagcagcagcacgaAGAGCAGTGACCTCCAGCAGCAGGTATCCTACGGTCGAGCAGTGCCCGTACCCGCACCCATTGCCAGCGATGTTCGACCCACCTGCCTGATCTGCGCCAAAACGTTCCAGCGCCAGCATCAGTTGACGCTGCACATGAACATCCATTACATGGAGCGCAAGTTCAAGTGTGAGCCCTGCAGCATTTCCTTCCGCACGCAGGGACATCTGCAGAAGCACGAACGTTCCGAGGCGCACAAGAACAAGGTGATGATGACGTCCACGTTTGGTGTGCCCACCACCTCGAATCCGAGGCCGTTCGAGTGCACCGACTGCAAGATCGCTTTTCGCATCCACGGCCATTTGGCCAAGCATCTGCGCTCGAAGACGCATGTCCAGAAGCTGGAGTGCCTGCAGAAGCTGCCTTTTGGCACCTACGCGGAGATCGAGCGGGCTGGCATCAGTCTGACGGAGATCGATACCAGTGACTGTGACAATTCGTTGATATCCCTGAAGTTGCTGGCTCAGAAATTGCTGGAGAAGGATCCGAATAAGCTGAGTGGCTACACGACACCATCGGGCATGATGCAGCTGGCCCAGGACCCAGCGAATCCTGCCTCGCAGGATAGTGCCTCCGAAGATGGGTTCAGTGCGGCCGTGGCCATAGCCTCGGCCATTGCTTCGCTGGACAATGACAGTGCTGGGAACACACCGAAGCGAGCCAACTCGATGTCCGAGGATGAAACTGTGGCCAATGGCCTAAATCACAATCTGAAGCGGCGATTGCCTGGCAGTTTCAGCAGCACGGGCGAGGAAAGCGATAATCCCACGGGCGAGGGCGAGAAGCGTGCTCGTTCCAGCCAGGACTTACCTGTGGCCGTGCCCGTACCCGTTGCTGCTTcaccggcagcggcagccagcaACTGA
Protein Sequence
MENASTTTAKHYKTAGKQYKTNKKFKRLASTTEVESGSATANGGPLTDAGMRTTSLSSNSSLSPPPMVSNGHHLTQQQQQQQQQQSRPPAITTTHEFSANFVNSNHVNAIGQEESNSHKVALNARTRMPLTNSSGTSTSSSSNYAANATLTPATFAQHQQLTQPTAGGAGIAGGGGIPGGGAVGEKAGRYVCPYCNLICAKPSVLEKHIRAHTNERPYPCDTCGIAFKTKSNLYKHCRSRSHAARARGLEVPADADDGLSDQDAELSNSSSELPSRAGSPYDEPMSSPTPSPSTLSATKSAYIQQPPPLPQHMQQLPLGSPAAGTLPPTTSDQLHSATAQHRPSIDYKPYKPKFHNASLYAPGSSKEQQQQQQQQLQLQQQQQQQQQHQQLAQQKLSIQLPLVQQQPSLTHPTLSPSTQMKMKNHINSHQLQMQLQHQLHAQQSLLASMPPVPPAGVYYLGQSPYYNPDPAAIQHSALVFHQFQLQQMHLQQQQQQQLQQQQQQQQQQLQQQQQQHSPLVKAPQQPASLPPQQLVRANSQVSNVTPAPATPTPAAAANLSSFASSSGSMQVNVAKVQEHISKLISQNEAIVENKEILLQKKYPKQLNRSRSFNNANSNSSSSNNAANAAAALHANSNNSSHNLSAQMPERETKVNLAQAIVQKQQQQQQQQQHQLQQQQLQQQQQQLQQQSALEQQHFMYALQQQQQQQQESQQPQPQLLEPPNGLTKRNSYKPPPQAMTTTTPVKQQQQQQQQQLPPPPSPLPMQTMQYRQDPATPVAKMEQPATAVHVMPLNLSAKPKPAVITVPVSSLSNSLVPATSTSSSGAAAGSTKAASAPGQVNNSIIKNLLLNARGLAVPIGEGEDAVYSCPICASEFRSADDLKLHNSTYCQDASSSAPMSPASSPFRSNSISLSLPELKSHMANSKNPLSLAKLAWSQLETKRSSLVASCLNAAQTPARTSTVTAALTSAPVTAPAPAPATAPAPAPAPAPAPAPAPAPAPAPAQLPLEGLRFVDAPLPSPGPLLGKTPLVDYAQQNAPRKPQQDSVVITKMHEDRLFAILDLEAQPAKRVKTSDSTQAFSFPFTNHNNNNSAQDAQPVKEERLHRFTSSGGSMIPISECPDLENSPKMIRTPLLSGGSFQDVSVKVIEERGSSKERKLMALVSGSGLLAANAGPQHFQFPPINSITAFNPLTLPLTMSGAGGGDKSTPVTPIPYVPGIPGPGSLTPQMPLLPPPPQQLQLPVPSGRGRSPNRKQPSPLLMAAGAGDLKALSPFGGVQNLPSEFSRQPPTPAQRQALQWNSKEATPKKAAAPFNFLRMADNVKTAPEPEVRHFNLDNVIGGKQQQQQQESPLTPLHVETPNGNATEEASPSTSAKSKFLRPTSLPLKPGTFTPKRHHGITPTANTLPLISPETPRPSKSCVQLYLNGHAYTYLGLKCSTKMFYCTVNCPQPSYVAGMHKLSMYSVWQVCEENQPHPLGFKLKKVMSLYDSRQRMLGNGSSTAMAGSGKLSYNVVSSQQTVSSTSTLVSASASVFYQNQLKTPPAVVSVLSEANVAAKANEEEEAEAAAQAKKLETSPSGQPLVGGYESHEDYTYIRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPFTCSHCNFSFKTKGNLTKHMQSKTHFKKCIELGINPGPMPADGEFLDVDMDFDQQSSTSAGGRTSSMAGESDSDDYSDNESESSDTDESKSRLKEHEAARCLLSLSMTPPIPQSVSPYPQHLQDTPLPAASPANSIGSSGSLPKRLVCSFTSPKPPFDYQKQEQYYSNPEESKPKRSVASEESAPMDLTKPRGLMMSSAVSPVPPSPVPPPKSQAQQMHDVIFGSSGNESGFMKTLISVSDKVRISAEMEELAKHEARSEVQDVLLQTYIKEQARLNAKRKLSQLSDTYLINTLISKAAATAGTATTVMSSSGSSLLTTGSRPIMTINEVPSIEVHEVKTPEAVELPAIPPATPTAIPTGTATATGTPTATPTPTATGTATTTPTPTPITVKMVQDESDESDQEKPLAEPHNANLPAAVQQKDANDFTGVLGQPPHSQATGGAAAAAAASAAAVATSTSASVAIPTTSNNTQPTQRTVIVGEDGFKSSTPTSSSSTKSSDLQQQVSYGRAVPVPAPIASDVRPTCLICAKTFQRQHQLTLHMNIHYMERKFKCEPCSISFRTQGHLQKHERSEAHKNKVMMTSTFGVPTTSNPRPFECTDCKIAFRIHGHLAKHLRSKTHVQKLECLQKLPFGTYAEIERAGISLTEIDTSDCDNSLISLKLLAQKLLEKDPNKLSGYTTPSGMMQLAQDPANPASQDSASEDGFSAAVAIASAIASLDNDSAGNTPKRANSMSEDETVANGLNHNLKRRLPGSFSSTGEESDNPTGEGEKRARSSQDLPVAVPVPVAASPAAAASN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00594759;
90% Identity
-
80% Identity
-