Dkan012786.1
Basic Information
- Insect
- Drosophila kanapiae
- Gene Symbol
- -
- Assembly
- GCA_008042475.1
- Location
- VNJM01001060.1:57184-59657[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.0067 0.53 10.9 0.3 2 23 30 51 29 51 0.96 2 13 0.049 3.9 8.2 2.3 1 23 57 80 57 80 0.93 3 13 0.0086 0.69 10.5 1.3 1 19 94 112 94 115 0.93 4 13 2.2 1.8e+02 3.0 2.4 2 22 131 151 130 151 0.93 5 13 0.3 24 5.7 2.0 2 23 400 422 399 422 0.94 6 13 0.025 2 9.1 0.6 1 23 447 469 447 469 0.97 7 13 0.0049 0.39 11.3 1.6 1 23 477 501 477 501 0.95 8 13 0.11 8.6 7.1 2.4 2 23 506 528 505 528 0.95 9 13 0.00027 0.022 15.3 0.2 2 21 541 560 540 561 0.93 10 13 0.0071 0.57 10.8 0.4 3 23 571 591 569 591 0.97 11 13 8.3e-07 6.6e-05 23.2 2.8 1 23 597 620 597 620 0.98 12 13 3.3e-05 0.0026 18.2 1.4 1 23 626 648 626 648 0.98 13 13 0.00031 0.024 15.1 2.9 1 23 654 676 654 676 0.95
Sequence Information
- Coding Sequence
- ATGgcccccagcagcagcagtgcggcagccgctgctgcagccacCAAATTGCTGGTGGAGATCACCACCGATGGCGTGCCCAAGCTGCACTGCCCGGTGTGCAACAAGGCCCTGGTCTCTTTGGCCGGCTATGTAAAGCACGTCAAGAAGCACCAGCCGCCGGGCGGCTTCGAGTGCCGCAGCTGCGACGCTCGCTATTGCCACGAGGAGGAGTTGACTCAGCACGCCAAGGATGAACATGGAGCCACCGGCTCAGCCGCTGCCCAAGAACGCAAGCCCTTTGTCTGCGAGAAGTGCGGGGCGGAGTACAGGTACCAGGAGGCATATCGACGCCACTGTAGGACCAAGTGTGGCGAGGAAAAGTTACCGAAGGAGGAGACCCGACCCGTGGAGTGCAGTTCATGCTACACTCGCTTCTCCTGCTTCGCCAGTCTGACCAAGCATCGGCGCAGTCGTCCCGAGACCTGCGGCCAGCCAGAGTACGATGTGCCGGGAGAGTTGGAAGGAAGGAAGCGGAAAGCTTACCGCAAGAAGGGAAGGCAGAGGGACTCCGATGATGAGACCACCTCGGAGGACTCGGAGGAGGACAGTGACGATGACATTCCACTGGCCAGCCGGCTGAAGACGAAGCTCAAGCAGGAGAGCCAGTTCTCGGACTCGGGCGACGAGTGTCCCGACTTCGAGCCCAACAACAGTGAGGACGAGGCGGATTCTTCCGGATTtaagctgccgccgccggccaTGGTCAAGGTGGAGGCCTTCGACGAGGAGGACTTCGAGTACCAGGATGCCAGCATGTATGTGAAGACAGAGAGCACGGATATATTTAGCAACGAGAAGGATAAGCTCCTGGATGTGCTGCTTAACGAGGGCGATGGCCTGAAGCCCTTCGAGAGCCTGAAGGTGGAGCAGGGCGCCGGTATACTGGACGAGATTGCGGCCGTGCCGCTGGTGGAGGTGGCCGAGGAGGATGTACTGTCCCTGCGGGGACCGCGCAAGGAGGAGGTTGTAAAGCGGAAGCGAGGCAGGCCGCCCAAGGAGAAGATACCAGTTATCAAGCGAAAGTATCGCAAGCGCAACGCACCGAGGTCGCCCTCGCCTGAGGATTCACCCGGAACACCCAAGCGCGTGGCCAAGATCAGCAAGAAGGAGCTAAAGGAGCGCCTCAAGATGATCAACAAGATGGAAAAGTCCTGGAAGTGTCCACATTGCGTCAAGATCTATCACATTCGCAAGCCCTACGAGAAGCATTTGCGCGACGACCACAAACTCAACGAGCAAGAGATGAAGGAGATCTTCAAGGACGTGGACGTGCATGCCAAGCTGGACGAGGAAGTATTCAAGTGCAACATCTGCAGCAAGATCTATCTGGTCGAGAAGCGCCTAGTCACCCACATGAAGGTGCACGGCGAGGACGGCAAATTGACCTTTAAGTGTCCGTGCTACTGCAACCTGTTCTTCGCCACCAAGGAACAGGCCACGGAACATGCCCGGGCACAGCACAAGGAGCTGCTTTACTGCGAGAAGTGCGACAAGTACATGACCGGCCACGACAGCCTCAAGAACCACGAACGCAATTTCCACTCGAAGAAGGAGCCGCGCAGCCAGCAGCGCAACCTCATCTGCGACAAGTGCGGCAAGAAGTTCACCGGACGCACCTCGCTCTCCGACCATGTGCGCTCCGACTGCGGCCGCCTGCCACTCTACGGCTGCACCGTTTGCGGCAAGCATTTGTCCACAGCTGGCATTCTCAAGACGCACATGCTCCTGCACAAAGCAGACACTCCCTACCAGTGCGACAAGTGCGGCAAGACGTTCAAGGTGAAGGCGCAGTACAAGTCGCATTTGAAGACAAGGCACACCGACTACAAGCCGTACAAGTGTCACCTCTGCCCCAAGGAGTATCCGTACAGGGAGAGCCTGCTCACCCACATGACCGTGCACACGGGCATCAAGCGTTTCCTTTGCAACAATTGCGGCAAACGCTTCACCTGCATCTCCAACCTGCAGGCCCATCGCAAGGTGCACGCAGATACCTGCGGCCAGCTGCCGTTAAATGCCAAGGCCACCCAATACATGGGCGTGCAGCGTGGCAAGCTCTTGATGGGCGCCAAGCCCGAGGCGGGCATGGAGTATGAGGAGACCAAGACACTGATCGCACAGGACGTAATCGATAGGGATATGCCCATGGCCCAGGAGCTGAATTTCCCATCCGACGGCTCGGCACCGCTTGCCACCGTGCCGTTGAATTATGCCTCCTCGCACCTGGTGCCGCACATCGTGCTCCAGACCATGCAGGCCGAGGCCCGGCGATTGGAGTAA
- Protein Sequence
- MAPSSSSAAAAAAATKLLVEITTDGVPKLHCPVCNKALVSLAGYVKHVKKHQPPGGFECRSCDARYCHEEELTQHAKDEHGATGSAAAQERKPFVCEKCGAEYRYQEAYRRHCRTKCGEEKLPKEETRPVECSSCYTRFSCFASLTKHRRSRPETCGQPEYDVPGELEGRKRKAYRKKGRQRDSDDETTSEDSEEDSDDDIPLASRLKTKLKQESQFSDSGDECPDFEPNNSEDEADSSGFKLPPPAMVKVEAFDEEDFEYQDASMYVKTESTDIFSNEKDKLLDVLLNEGDGLKPFESLKVEQGAGILDEIAAVPLVEVAEEDVLSLRGPRKEEVVKRKRGRPPKEKIPVIKRKYRKRNAPRSPSPEDSPGTPKRVAKISKKELKERLKMINKMEKSWKCPHCVKIYHIRKPYEKHLRDDHKLNEQEMKEIFKDVDVHAKLDEEVFKCNICSKIYLVEKRLVTHMKVHGEDGKLTFKCPCYCNLFFATKEQATEHARAQHKELLYCEKCDKYMTGHDSLKNHERNFHSKKEPRSQQRNLICDKCGKKFTGRTSLSDHVRSDCGRLPLYGCTVCGKHLSTAGILKTHMLLHKADTPYQCDKCGKTFKVKAQYKSHLKTRHTDYKPYKCHLCPKEYPYRESLLTHMTVHTGIKRFLCNNCGKRFTCISNLQAHRKVHADTCGQLPLNAKATQYMGVQRGKLLMGAKPEAGMEYEETKTLIAQDVIDRDMPMAQELNFPSDGSAPLATVPLNYASSHLVPHIVLQTMQAEARRLE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00615081;
- 90% Identity
- iTF_00606536;
- 80% Identity
- -