Basic Information

Insect: Drosophila kanapiae
Gene Symbol: esg
Assembly: GCA_008042475.1
Location: VNJM01000989.1:204314-206267[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 6.7e-06 0.00053 20.3 3.7 1 23 279 301 279 301 0.99

2 6 6.8e-06 0.00054 20.3 3.7 1 23 356 378 356 378 0.97

3 6 9.6e-07 7.6e-05 23.0 0.6 1 23 391 413 391 413 0.98

4 6 3e-08 2.4e-06 27.7 0.4 1 23 417 439 417 439 0.97

5 6 3.4e-08 2.7e-06 27.6 2.1 1 23 445 467 445 467 0.98

6 6 4.5e-06 0.00036 20.9 0.4 1 21 473 493 473 494 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	6.7e-06	0.00053	20.3	3.7	1	23	279	301	279	301	0.99
2	6	6.8e-06	0.00054	20.3	3.7	1	23	356	378	356	378	0.97
3	6	9.6e-07	7.6e-05	23.0	0.6	1	23	391	413	391	413	0.98
4	6	3e-08	2.4e-06	27.7	0.4	1	23	417	439	417	439	0.97
5	6	3.4e-08	2.7e-06	27.6	2.1	1	23	445	467	445	467	0.98
6	6	4.5e-06	0.00036	20.9	0.4	1	21	473	493	473	494	0.95

Sequence Information

Coding Sequence: ATGGATAAACTCAAGTACAGCCGCTGTCCGCTCAAGAAGCGTCCGATAATGGTGGAGGAGTCCTGTCAGGAGGATCACTTAAGTCTCGACGAAGGACCCGTGGACTTGAGTGTGGCCTCTGCAGCTGTTCCCCTGGAACCGCATTGGTCGGCGAAAGCGGAACCGGAACCGCAGGCCGTACCCCCAGAGCTGAGGCGTCGCTTCGACGCGGCCATGAATCAGACCAAGGAGCAGCTGGCCCGTCGCATTTGGGAGGAGACCCGGGAGATAGCCCGTGCCTTTCCCGATGTCTTCACCCGCGAAGAGATCGCGAAGAGCCTGGCGCGCTTGGGTTACGGCGAATTCGAGCTGCCACCGGAGGAGGAGGTAATGGAGCCCGAAGCAGATCCAGAACCCCAGCCTGAGCCAGAGCACCAAATTCCGCTGAGCTATGCCAGAGAGACAGTCCCCACCGTGATTAAAGTAGAGCCCACCGAACAGGACTTTCCCCTGCGGAACTACAACAATAATCTGCTCAAGAGCATAGCGGAGTACGAGGACTGCATGAAGATGCAGCCGATCAAGGAGGAGATGGTGCCTGTGCCACAGCCGCCGATGTACTATCCACCGCCCACTCCGCTTGCCGAGCCCGAGGATCTCTCGGTGACCCAGAGGCGGGTGCTCAGCGAGAACATGAACCTACAGAATGTGGCCAGAGCTCTGCTCAGCATGCAGCACATGGCGCCACTTCCGCATCCGCTTCCGCATCCTGTTCTGCCGCCACAGGACATGGAAGAGGACCAGGAGAATCAGGACCTCAATCCGCTGAAGATCAAGAGCAGCAACGACCTGTACTACCAGTGCCAGCAGTGCAACAAGTGCTACTCCACCTATGCCGGCCTGGTGAAGCACCAACAGACCCACGCCTACGAGAGCACCGAGTACAAGATCATCCGGAGCCAGCCTGGGGGATCGGGCCCCATAGTGGACCAGACAGAGTTCTGCACAGACCAGGCATCGGCCTTGATCCAGGCGGCCAATGCCGCCTCGGCTCAGAGCATGCAGAAGCCGGTGGGCGTGCCACGATACCATTGCCAGGACTGCGGCAAGAGCTACTCCACCTACTCCGGCCTGTCCAAGCACCAGCAGTTCCACTGCCCCTCGGCGGAGGGCAATCAGGTGAAGAAGGTGTTCAGCTGCAAGAACTGCGACAAGACCTACGTCTCCCTGGGGGCCCTCAAGATGCACATTCGCACCCACACGCTGCCCTGCAAGTGCCCCATTTGCGGCAAGGCCTTCTCGCGACCCTGGCTCCTCCAGGGGCACATCCGCACCCACACGGGCGAGAAGCCCTTCAGCTGCCAGCACTGCAACCGAGCCTTTGCCGACCGCTCCAATCTCCGGGCTCACATGCAAACCCATTCGGATGTGAAGAAGTACTCCTGCCCCACCTGCACCAAGTCCTTTTCCCGAATGTCCCTGCTGGCCAAGCACTTGCAGAGCGGCTGCCAGAGCGAGCAGAACGGCGGCCCGGGCGGATCGTCCAGCGGTGGCttcgaccagcagcagctgcagcagcatctccaGGGCTACGAGGAGGGTCACAATCCCCACCAGGTCTACTATGCCGGCAGCgtgggcagcagcaacggggaggaggaggaggccggCGACTACcccatgccgccgccaccagccttatattaa
Protein Sequence: MDKLKYSRCPLKKRPIMVEESCQEDHLSLDEGPVDLSVASAAVPLEPHWSAKAEPEPQAVPPELRRRFDAAMNQTKEQLARRIWEETREIARAFPDVFTREEIAKSLARLGYGEFELPPEEEVMEPEADPEPQPEPEHQIPLSYARETVPTVIKVEPTEQDFPLRNYNNNLLKSIAEYEDCMKMQPIKEEMVPVPQPPMYYPPPTPLAEPEDLSVTQRRVLSENMNLQNVARALLSMQHMAPLPHPLPHPVLPPQDMEEDQENQDLNPLKIKSSNDLYYQCQQCNKCYSTYAGLVKHQQTHAYESTEYKIIRSQPGGSGPIVDQTEFCTDQASALIQAANAASAQSMQKPVGVPRYHCQDCGKSYSTYSGLSKHQQFHCPSAEGNQVKKVFSCKNCDKTYVSLGALKMHIRTHTLPCKCPICGKAFSRPWLLQGHIRTHTGEKPFSCQHCNRAFADRSNLRAHMQTHSDVKKYSCPTCTKSFSRMSLLAKHLQSGCQSEQNGGPGGSSSGGFDQQQLQQHLQGYEEGHNPHQVYYAGSVGSSNGEEEEAGDYPMPPPPALY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00486734;
90% Identity: iTF_00602776;
80% Identity: -