Dkan010724.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila kanapiae
Gene Symbol
Paris
Assembly
GCA_008042475.1
Location
VNJM01001283.1:63839-66845[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 9.9e-07 7.9e-05 22.9 3.1 1 23 132 154 125 154 0.98
2 17 2.4e-07 1.9e-05 24.9 0.8 1 23 160 182 160 182 0.99
3 17 0.0083 0.66 10.6 9.7 1 23 188 210 188 210 0.99
4 17 3.3e-06 0.00027 21.3 2.2 1 23 216 238 216 238 0.99
5 17 2.4e-08 1.9e-06 28.0 4.9 1 23 244 266 244 266 0.98
6 17 0.00048 0.038 14.5 2.6 1 21 272 292 272 293 0.95
7 17 3.4e-06 0.00027 21.3 3.6 1 23 497 519 497 519 0.99
8 17 8.6e-05 0.0069 16.8 2.4 1 23 525 547 525 547 0.99
9 17 2.7e-05 0.0021 18.4 1.6 1 23 553 575 553 575 0.97
10 17 0.00012 0.0092 16.4 1.9 1 23 581 603 581 603 0.98
11 17 7.3e-07 5.8e-05 23.4 2.5 1 23 609 631 609 631 0.98
12 17 6.5e-07 5.2e-05 23.5 1.6 1 23 637 659 637 659 0.98
13 17 1.7e-06 0.00014 22.2 1.1 2 23 666 687 665 687 0.96
14 17 0.00015 0.012 16.1 0.1 1 22 693 714 693 714 0.96
15 17 0.02 1.6 9.4 0.0 2 23 722 744 721 744 0.92
16 17 0.00061 0.048 14.2 1.2 1 21 760 780 760 781 0.95
17 17 0.018 1.5 9.5 0.5 3 23 790 811 789 811 0.95

Sequence Information

Coding Sequence
ATGGAGAACATCTGCCGCGTGTGCCTGGGAAGTTCAAAAGATCTGATTGACATTTTCAATGATAGGCGAAAACTGGATATACCGGGCATGATCGCGCAGTGCACAGGCTTTGAAGTTAAATCCGGCGATTCGTTACCGACAACCATTTGCCCGCCCTGCCTGGAGGATGCTCAAAATGCATTTGATATACGGCAAACAGGCAAGCGGAGCTACCAGTTCTTCTGCCAAGTGCGGGATGAGGGCATTGAAGAAGCCCTGTGTGCCTTGCTTGAGGAAGAGGACTGGGAGATCCCCGAATTGGAGAAAGCCGAATGTGAGGGTGAAAGCACTGATAAAGGAATTCCCCCCAAGAGCCAGGGGAAGAACGAAAAGGACAAGGTTCAGTTGAACAGACATCAATGCACATTGTGTCCGAAATCCTTTCGGCATAAAGCGTCTCTCCAGCTGCACATACGATATCACGCGGGAGAAAAGACCTTTGAGTGCTCGCACTGCTCTAAGAAATTCGTCAACCCGGCTGCCCTCCAAATACACATCCGCACACACACGGGAGAGCGACCGTACAAGTGCACCCACTGCTCGAAGTCCTTCGCGCAGCATTCCACCCACAAGTCGCACGTCCGGACGCACACTGGCGAGCGGCCGTACAAGTGCACCCAGTGCTCCAAGTCCTTTTCGAGGGGTACAGATCTCCTGCGACATGAGCGCACTCATGCGGGAATTCGTCCGCACAAATGCTCCTATTGCGGAAAGTCCTTCGCCAGAAAGTCGCATCTCCGGGATCACATTCGCATTCACACTGACGAACGACCCTTCCAGTGTTCCCATTGCCCGAAGTCATTCCATCTGAAGCAGCAGCTCCGAAGCCACACCATGGCTCTTTCAGAgACAATGGAGACCGTGTGCCGCGTGTGCATGCTAAGCTCCGCAGCTACCTTGAATATCTTCGATGGAACGGAAAAGTCTGACGTTTCTATTGCGGATATAGTTTCTTCGTTTATGGGCTTTAAAGTTAGGCAAGGAGACTCATTTCCGGAAAACATATGCCAACTGTGCCTGCAGGATGCGCGGAACGCGTTCAACAGAAGACAAGCGCTCGAGGAGCACCACCGGTTGCAAACCCAAGTgaaagaagaaaaggaaattcaTCGGATGAAGCAGGAGGTGGCTGGAGAGGATTTGCTCGAGGAAGAAGTCTGCAGGGTATCAGACTGCGAGCGTGAGACGTCGCCCAGTGCAGAGCAGGGTTATCTCCACGAAATTCCAGTCAAGTACGAGGAGAGCGACGAAGATGCGTCTCTGGCCAGTCATCCCATGCAGTTCGATATTAAAGTGAAGAACGAGCGAATCGAAGAAGACCAGCTGGAGGATGAGGGCCCAACTGAAGAATCCACTAGCGATGAGGACTCCAACGCATTCGAATGCGTAGTGAAGGTCGAGGAGAATGACGAGGAGCACGATGAGGACAATACCAATAGTAATCAGTCCTTTAAATGCCCTCACTGTCCAAGCTCCTACACGCGAAAAACCAGTCTTAACTCACACATCCGAAAGCACACGGGAGAACGCCCCTACACTTGCTCCCACTGCCAGAGTTCTTTCACTGTGAAGCGCCAGCTCGAAGATCACGTTCGGATACACACGGGGGAACGTCCGTTCGCGTGTGGCCAGTGTGAGAAGTCCTTCAGAAAGAGGACCGATTTGAAGCTTCATAAGCGCATCCACTTAGAAGTTCGGCCATTCCAGTGTTCCCAGTGCTCGAAGTCCTTTGTGAGAAGATACCGCCTTGTAGAACACACTCTTAGCCACTCCGGGGAGCGACCTTTTCAGTGTCCCCATTGCCAGAAGAGCTTTACCACCAAAGTTAGGCTGCAGGTACACATCGACACCCATTTGGAGGAGAAGGTTCACCAGTGCTCCGAGTGCCCCAAAGCGTTCAAAAATCGCCGGAATCTTGTGGATCATATTCGTAACCATGCGAAAGAGCAGCATCTCAGGTGCACTGAGTGCCCGAAAACTTTTGTACATCCCAGCAGCCTCCGGACACACCTTCTACTCCACACAACAGAGCGGCCCCACAAATGCCTCGTTTGCGGCGCGGCCTTTACTCTGCCGGCCGGCCTGAGGAAACATATGAAAACGGATTGTTATAAGAAGTTGATCCAGTGCCCGCAGTGCCCAGCGTCTTTTAGGTTTCCCGAAATTCTCCGCGAACACATTATCGCTCTTCATCCGGACACATCATTGGAGTCAATACCAGCGCCCCCGGAAAGGCCGCACAAGTGCACCGTGTGCTCGGCCGCCTTTGCTAAAAAGCGCTACCTCAGGAGCCACATGCAAAGGAATTGTTATAAGAATCTGAACAATTGCTTGCAATGCTCCGTATCCTGTAAAAGTCCCGAACTTCTGCGGGAGCACATTATCTCCGCTCATCCCTTAACACccataataaatgaaaaatga
Protein Sequence
MENICRVCLGSSKDLIDIFNDRRKLDIPGMIAQCTGFEVKSGDSLPTTICPPCLEDAQNAFDIRQTGKRSYQFFCQVRDEGIEEALCALLEEEDWEIPELEKAECEGESTDKGIPPKSQGKNEKDKVQLNRHQCTLCPKSFRHKASLQLHIRYHAGEKTFECSHCSKKFVNPAALQIHIRTHTGERPYKCTHCSKSFAQHSTHKSHVRTHTGERPYKCTQCSKSFSRGTDLLRHERTHAGIRPHKCSYCGKSFARKSHLRDHIRIHTDERPFQCSHCPKSFHLKQQLRSHTMALSETMETVCRVCMLSSAATLNIFDGTEKSDVSIADIVSSFMGFKVRQGDSFPENICQLCLQDARNAFNRRQALEEHHRLQTQVKEEKEIHRMKQEVAGEDLLEEEVCRVSDCERETSPSAEQGYLHEIPVKYEESDEDASLASHPMQFDIKVKNERIEEDQLEDEGPTEESTSDEDSNAFECVVKVEENDEEHDEDNTNSNQSFKCPHCPSSYTRKTSLNSHIRKHTGERPYTCSHCQSSFTVKRQLEDHVRIHTGERPFACGQCEKSFRKRTDLKLHKRIHLEVRPFQCSQCSKSFVRRYRLVEHTLSHSGERPFQCPHCQKSFTTKVRLQVHIDTHLEEKVHQCSECPKAFKNRRNLVDHIRNHAKEQHLRCTECPKTFVHPSSLRTHLLLHTTERPHKCLVCGAAFTLPAGLRKHMKTDCYKKLIQCPQCPASFRFPEILREHIIALHPDTSLESIPAPPERPHKCTVCSAAFAKKRYLRSHMQRNCYKNLNNCLQCSVSCKSPELLREHIISAHPLTPIINEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
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90% Identity
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80% Identity
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