Basic Information

Insect: Drosophila kambysellisi
Gene Symbol: zld
Assembly: GCA_035042185.1
Location: JAWNLS010000691.1:2110209-2115434[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 3 2.1e+02 2.7 0.4 2 23 335 357 334 357 0.88

2 6 0.0047 0.33 11.6 2.9 1 23 642 666 642 666 0.92

3 6 0.0076 0.53 10.9 4.0 2 23 1503 1525 1502 1525 0.95

4 6 0.51 36 5.2 3.4 1 22 1531 1552 1531 1553 0.75

5 6 0.0017 0.12 13.0 4.4 1 23 1560 1583 1560 1583 0.92

6 6 4e-05 0.0028 18.1 6.6 1 23 1589 1611 1589 1611 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	3	2.1e+02	2.7	0.4	2	23	335	357	334	357	0.88
2	6	0.0047	0.33	11.6	2.9	1	23	642	666	642	666	0.92
3	6	0.0076	0.53	10.9	4.0	2	23	1503	1525	1502	1525	0.95
4	6	0.51	36	5.2	3.4	1	22	1531	1552	1531	1553	0.75
5	6	0.0017	0.12	13.0	4.4	1	23	1560	1583	1560	1583	0.92
6	6	4e-05	0.0028	18.1	6.6	1	23	1589	1611	1589	1611	0.97

Sequence Information

Coding Sequence: ATGGCGAGCATAAAAAGTGAAATGCCGCCACTGCACGCGGCCGAGACGCTaacagccgccgccgccagcagcagtagtagcaGCGGCATTGCAACAgacagcggcggcggcagtagcagcagcaacaacagcacaacaacaacaccagcagcagcgacaacaacaacagcggcagcaacatcaacagcaacagttgcaactgttgctgctgcctcgcCAAATGCGAATGGAACAATCAGCGCCGCTGCCGACTCCAGTGATAATCAGCCAGGCACGccgcagccaacaacaacagcgacaacaccagcagccacaccagcaacagcagcagcagcggcaacaacaacaacacaccagcagcagcaacagtctcTAATCTCTGCCgaggcacagcagcagcaacagttgtcgTCGGGCATAACACATCAGCCTTATGCCACACATCAAATGTATgccgcacagcagcagcaacagcagcagcagcagcatctctACTACGCCAGCgatatgcagcagcaacagttgcagcaccAACAACCCAGCTACGCAGCCAGCAGCTACATCAACAGCTACGAGCAATtctatcagcaacagcagcagcaacagcaacaacagcaaagtgtTGCTGCCGTTTCCGATTATGGCAGCGCTTATATTGACTACAGCAAAGTGTCCGCAGTGCGTTATCATCCATATTTGCAACAGCCGACTTCAGtgttgccaccaccaccaccagcaacgggagcagcagcagccgccgcagcagcagcagccgcagcaacagttgcagcagcagctgatgagTCATCATccgcggcagcagcagtggcggGAGCGGGTGCGggtgcaacagttgctgttaGCAGCAGTAttgcagcaacggcagcaatgAGTCCGCGTgtcgtcagcagcagcagtcccACATCGACGTCGTCACACTTGCAACTGAGCAGCGTGACGCCCAGTTCGCCGGGTGGTGGCGGGGGTGGCAACTGCAAATTGCAGTGCAAAAAATGTGGCATACTTAACACAAACGAAACGGAGTTGCACGAACACATCGCCAATGTGCACGGAGAGTCGCCGTATGGCAGCAGCGGCTACGCCAGCTCACCCTACATTAAGGAGGAGTTGCCGTCGGCGACGCCAACCGTTGCCAGTGGCGAGCTGCTTGATTTGGACTCGCAAAAGATGGTCTACCACCAgcaattgctgcaacagcagcagcaacagcaacaattgtcgcagcaacagcagcaacaacaattgtcgcAACATGATCTTGTTGCTGGTTTGCCGTTGGCATTGCCAGATCCGTTGCATTCGATGCAATCTATGCAACAGCGTGCACTACACAGCtgggagcaacagcaacatcagcagcaacatcatcagcagcagcagcagcaacatcatcaccagcaacatcaccaacaacatcaacagcagcaacagcagcagcaacacttgcaacaacatcagcctGGTGTTGAAGGTTTGCCGGCATATATGCAACCATTGCTGGAGAAGTCGCCGCATCATTATTACGCAACGAAACAGTCGCCGTATCAGCCGATGATCAAGCAGGAATATCTCATCAAATCGGAATACGCCGATTCGCAGCATTATGTGGATAAATCGTTCGATCCGACGGCAGCCGAGGTAACAACCAGTCCGGCCGAATATCCAAGCACAACCACTGGCAATCCATCAGTTGCCGTTGCTGGCAATGATGCaacttctgttgctgctgcaacgggtggtggtggtggtgcaggtgCAGGTGCAGGTACAACGGGTGGATCGGGCGGTGCAGCAGCATATCGCAACTTTGAGCCACCCAGCTCGAGTTCGGTGCTGCCCGCCAACAGTTTAACGGCCAAGGCGGCCACCTGGAAATCGAATGAGGCACGTCGTCCAAAAACCTACAATTGCACTGCGTGCAACAAGTGGTTCACCAGCTCTGGCCATTTGAAGCGACATTACAACACCACGTTGCACAAAAATGCGGTAAAGTCGAGTGGCCAACCGGATCCGGCCACTTTGCCAATTTCGGCGCATCATCATCCTGCTCGCGATCCCGTCACCAAGACCAGTCGTCGCGGgaatgctgcagcagcagcagccgccgcagcagccgccgccgcagcagccgcagcagcagcagcagctgcagcgggtGGAGGAACAACAGTTGGTGATGTGCCAACGGCACCGGAACCGCCGCGCAGTCCGCCGGACTATGGCGGTGTTTGTGGGGCGACGGGCGTGCCGGTGGGCGGCGCCATGTCGCAATATTCGGCCTCGCCGTCGCCCACCAATGCCgcccagcagcaccagcaacagttgctggcgagcagcagcaatggtTATGCGAGCAATGGCCATCACTATCATCATtacaacatgcaacagcaacaagtgcAATCGACGACAAACGCTTCTCCACAGCAtgctaacaacagcaacaacaacaacaacagcagcagcagcaacagcaacaacagcagcagcagcaacaacaactccgtTTTGAACGGTCACCCAAACGGGCTAGCAGGTCCCTCCGCccccatcaacaacaacaacaacaacaacacacaaatgcCGTCCTCCCAAATGAGGGGCCTGCtgaacaaaacaacaaccaccaccaacaacaacaacacaacaacaacaacaccaacaacaacagccacaattATAAAGATCGAACAAATGGAGGACAGCAACTCAGCAATGGTCatggaggagcagcaacagcagctggaacagctggagcagcagcagcaacagttggaggaacagcagcagcacgtcTTGCTGCAAACTGCTCACccaacacagcagcagcaagcgctCAGTtatcacagcagcaacagcaactcacCGCTTACTATTTACCACCAACAGCACctccaccaccaacaacaccaacagcagcaacaggagcaacaacaacagctgctgctgccgctgccgctgcagcagctgcagccgcagccgccgtcgcagcaggaggagggggagggggagcaccaccaccaacagcagcagcagcagcaactggagcaAGCAATGGATTTCTCGcgcaccaccatcaccaccaccatcacaacgccgccgctgctgccgccgccgctgcctaTGGgagcgctgctgccgcctaTGGGAATGGATTACAACATGCTGGCTTTGgatatgcagcagcagcaaccgcagcaacagctgtcGCCGCACAGCAATATGCTGtcgtgcagcagcaacatcagcatgcagcagctgcagctgccggcCATTATTACCACCACGCCCACCACGCCCATGCCCATGCACACGCCCATCACGCCCATGCCCACGCCCACCACGCCCATGCTGCCCATCATGCCCATCATGCCCATCAATATGGACATGGCATGCACCACTATGGGGCACCAATACCAGctgtcgccgccgccgccacagcagcagcaactcttgctggtggacaacagcaacagcaacagcagcagcagcaacagtataGCCAGCAGCCATAcgcccaacagcaacagcagcaacaacaacaaccacagcagcaacatcatcagcagcacagcagcaacaccgcCGCCGcacatcaccagcagcagcagcagcaccccacacatcaccagcagcaccaacagcagcaacagcagcagcagcaacaacagcaacaacaacatcaccaGCAACATTTGCTACCAGCAACTGCCGCCATTGCTGGAGCACACAATGAGCTATCACACTATTATTGGTAACGATGCGGTCCATTATGATGCCTAtgcgaacaacaataacaacagcaacagcagcgacatcGCTGCACACCATCAGCATCCCCATCAACATCCACAGATATTGCAACTAATGCCCGCCACGCTATTTGCACcatatgcagcagcagcagcagcggcggcacaTGCACCACTCTCCCCTTATTCGGTTGACGCTCAGCGTTCGCCGCAAGAGGGCGATTTGCCGCCGGTGCACACGTTGACGCATGCGTTGCACGTACAGCAGgaggcgcaacagcagcagcaccagcaacatctGCAACATCAGTCGGCAACATTAACATTgctgaccacgcccacaccatACTCGCCCACAGTGAGCAGTTCGCGTGCAACGCCAGCATTGGAATTGGACATGGCAATGGTCatggcacagcagcagcaacagcaacaggactATGAAATGGAGCAGCATtatctgcaacagcagcaacagcaacaactcgaacttgagcagctgcagcagcaacaattgcaacaacagcagcaacaacaacaacaacagcagcagcagcagcagcatcaacaacaacaacaacaacaaattgttgctgtgCTGCCGAAGAAGCGACGTGCTACTGccgtcacaacaacaacaacattaggTCAGCAGCCACCCAGCAAGCGAcgtcgcaacagcagcattggCTCAACATCGCCACATTCTACAACGTTGCCATCGGGTCGCATCAAGTGCTTGGAATGCGACAAGGAGTTCACCAAAAACTGCTACCTGACGCAACACAATAAATCGTTTCATTCTGGTGAGTATCCGTATCGGTGTCAAAAGTGTGGCAAGCGATTCCAGTGCGAAGATGTTTATACGACACATTTGGGGCGACATCGCACCCAGGATAAGCCGCACAAATGCGAACTGTGCCCCAAGCAATTCCATCACAAGACAGATCTGCGGCGACACGTGGAAGCGATTCACACGGGCCTCAAGCAGCACATGTGCGATATTTGTGAGAAGGGTTTCTGTCGCAAGGATCATCTGCGCAAGCATCTCGAGACCCACAATCGTCCGCGTGTCGTTGGCAAAaaggcggctgctgttgccgccgcaAAGTCTGCAacggctgcaacagcaacagcagcagcagtcgcatcagcggcagcagcagcagcaactcgaactgcaacagcagcagcaacagttgctagTTTGGCTATCAAACTGgacgatgttgctgctgatgatgatagtCTGCTTGATGATgaagacgatgatgatgatgttgctgacaatgatgatgttgatgaccATCAccatcaacggcaacagcaacagcaactgttgctcagCGGCGAGCATCATTTGATTAAAAACGAATTTGTTGATATTAAGCATGAATACGAGGATGAATACACCGATTATCAAATCATAGAAAAGGATATTGAATTGTATTAG
Protein Sequence: MASIKSEMPPLHAAETLTAAAASSSSSSGIATDSGGGSSSSNNSTTTTPAAATTTTAAATSTATVATVAAASPNANGTISAAADSSDNQPGTPQPTTTATTPAATPATAAAAATTTTHQQQQQSLISAEAQQQQQLSSGITHQPYATHQMYAAQQQQQQQQQHLYYASDMQQQQLQHQQPSYAASSYINSYEQFYQQQQQQQQQQQSVAAVSDYGSAYIDYSKVSAVRYHPYLQQPTSVLPPPPPATGAAAAAAAAAAAATVAAAADESSSAAAAVAGAGAGATVAVSSSIAATAAMSPRVVSSSSPTSTSSHLQLSSVTPSSPGGGGGGNCKLQCKKCGILNTNETELHEHIANVHGESPYGSSGYASSPYIKEELPSATPTVASGELLDLDSQKMVYHQQLLQQQQQQQQLSQQQQQQQLSQHDLVAGLPLALPDPLHSMQSMQQRALHSWEQQQHQQQHHQQQQQQHHHQQHHQQHQQQQQQQQHLQQHQPGVEGLPAYMQPLLEKSPHHYYATKQSPYQPMIKQEYLIKSEYADSQHYVDKSFDPTAAEVTTSPAEYPSTTTGNPSVAVAGNDATSVAAATGGGGGAGAGAGTTGGSGGAAAYRNFEPPSSSSVLPANSLTAKAATWKSNEARRPKTYNCTACNKWFTSSGHLKRHYNTTLHKNAVKSSGQPDPATLPISAHHHPARDPVTKTSRRGNAAAAAAAAAAAAAAAAAAAAAAAGGGTTVGDVPTAPEPPRSPPDYGGVCGATGVPVGGAMSQYSASPSPTNAAQQHQQQLLASSSNGYASNGHHYHHYNMQQQQVQSTTNASPQHANNSNNNNNSSSSNSNNSSSSNNNSVLNGHPNGLAGPSAPINNNNNNNTQMPSSQMRGLLNKTTTTTNNNNTTTTTPTTTATIIKIEQMEDSNSAMVMEEQQQQLEQLEQQQQQLEEQQQHVLLQTAHPTQQQQALSYHSSNSNSPLTIYHQQHLHHQQHQQQQQEQQQQLLLPLPLQQLQPQPPSQQEEGEGEHHHQQQQQQQLEQAMDFSRTTITTTITTPPLLPPPLPMGALLPPMGMDYNMLALDMQQQQPQQQLSPHSNMLSCSSNISMQQLQLPAIITTTPTTPMPMHTPITPMPTPTTPMLPIMPIMPINMDMACTTMGHQYQLSPPPPQQQQLLLVDNSNSNSSSSNSIASSHTPNSNSSNNNNHSSNIISSTAATPPPHITSSSSSTPHITSSTNSSNSSSSNNSNNNITSNICYQQLPPLLEHTMSYHTIIGNDAVHYDAYANNNNNSNSSDIAAHHQHPHQHPQILQLMPATLFAPYAAAAAAAAHAPLSPYSVDAQRSPQEGDLPPVHTLTHALHVQQEAQQQQHQQHLQHQSATLTLLTTPTPYSPTVSSSRATPALELDMAMVMAQQQQQQQDYEMEQHYLQQQQQQQLELEQLQQQQLQQQQQQQQQQQQQQQHQQQQQQQIVAVLPKKRRATAVTTTTTLGQQPPSKRRRNSSIGSTSPHSTTLPSGRIKCLECDKEFTKNCYLTQHNKSFHSGEYPYRCQKCGKRFQCEDVYTTHLGRHRTQDKPHKCELCPKQFHHKTDLRRHVEAIHTGLKQHMCDICEKGFCRKDHLRKHLETHNRPRVVGKKAAAVAAAKSATAATATAAAVASAAAAAATRTATAAATVASLAIKLDDVAADDDSLLDDEDDDDDVADNDDVDDHHHQRQQQQQLLLSGEHHLIKNEFVDIKHEYEDEYTDYQIIEKDIELY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00593484;
90% Identity: iTF_00482618;
80% Identity: -