Basic Information

Insect: Drosophila kambysellisi
Gene Symbol: ken1
Assembly: GCA_035042185.1
Location: JAWNLS010000077.1:10632143-10634455[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.066 4.6 8.0 5.9 3 23 239 259 237 259 0.96

2 12 0.0012 0.085 13.4 1.4 1 23 265 290 265 290 0.92

3 12 0.0021 0.14 12.7 1.5 1 23 297 322 297 322 0.93

4 12 0.00027 0.019 15.5 4.1 1 23 332 354 332 354 0.97

5 12 0.00019 0.014 15.9 1.8 2 23 362 383 361 383 0.96

6 12 0.078 5.4 7.7 0.7 1 23 389 411 389 411 0.97

7 12 0.052 3.6 8.3 2.6 1 23 417 440 417 440 0.97

8 12 0.019 1.3 9.7 4.1 1 23 446 468 446 468 0.95

9 12 0.0091 0.64 10.7 2.3 2 23 475 496 474 496 0.96

10 12 0.00017 0.012 16.1 0.8 1 23 581 604 581 604 0.96

11 12 0.0094 0.66 10.6 3.1 1 23 610 632 610 632 0.95

12 12 1.8e-05 0.0012 19.2 4.0 3 23 640 660 638 660 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.066	4.6	8.0	5.9	3	23	239	259	237	259	0.96
2	12	0.0012	0.085	13.4	1.4	1	23	265	290	265	290	0.92
3	12	0.0021	0.14	12.7	1.5	1	23	297	322	297	322	0.93
4	12	0.00027	0.019	15.5	4.1	1	23	332	354	332	354	0.97
5	12	0.00019	0.014	15.9	1.8	2	23	362	383	361	383	0.96
6	12	0.078	5.4	7.7	0.7	1	23	389	411	389	411	0.97
7	12	0.052	3.6	8.3	2.6	1	23	417	440	417	440	0.97
8	12	0.019	1.3	9.7	4.1	1	23	446	468	446	468	0.95
9	12	0.0091	0.64	10.7	2.3	2	23	475	496	474	496	0.96
10	12	0.00017	0.012	16.1	0.8	1	23	581	604	581	604	0.96
11	12	0.0094	0.66	10.6	3.1	1	23	610	632	610	632	0.95
12	12	1.8e-05	0.0012	19.2	4.0	3	23	640	660	638	660	0.97

Sequence Information

Coding Sequence: ATGAATGAGGGGAGCCAAACCTCCATACACGCAATATGCCGCACTTGCTTGTCAAGCCTGCAGCATGTTGCAGCACACGATTTGTTTGTGGTTCCAGGACTTGCCAAGAAACTGTGTGTCTGCACTTCACTCTCCGTTGAGCAGCACGATGGCTTCCCTAAGAACCTTTGCCCCAGTTGCTACACCCGGCTAAACGACTTACATGATTTCCAGCAAATATGCATGGACTCTGTACAAAAGCTGAAGGACTTGCTAGCTAGGAATCACTTTAGAATCCACACTAACGAAGTTGACAGTTTTGATGTGCTAAGTGTGGTGGCGCCACAGGATGCTGATGTGCCTGTCGAAGAAGATGATAACATCAACTTTGATCCGCTACTTAAtactaaaattgaaatatttgagaaTGAGGAGgatgtatttaaaatgctaGAAGATGTCGACAAAGAAGCAGAGCAGGTAGATATAGAAAAGGAGTCCTCAACTGGCAGCGAAAACGGCAATTATGATGCTGAAGAGAATAACAGCGACTCCGACGATACCTTACCCCTGTCCAGATTACGAAGTACTACCACGGAAGCTAAGCCGaataacgatgatgatgattgtaGATCGGGTTCAGAAGCGGATGCCAATGCGGAAGATAAAACCACGggtaaattaaaaagcaaGCGGATTCCAGCCGCGGAACGTGAGCTGCGTCAGCTAATCGATTGTCACATTTGCCACCAGAAGTTCAAGAAAGCAATTCGCTACGAGGAGCACATGAAGCATCACAATGACCTATTGCCATTCCAGTGCACTGTGGAAACCTGCAAGAAGGGTTTCACAACTGCCGCTGGTCTGCGACATCATGTGGATCATGCCCATTCGGAGCTCTGCGAATTGCATGCCTGCACCGTGGAAGGATGTGACCAAGCATTTCCCCGTACTCGAATGCTCACACATCACCTGAAAAAGGTCCACAACATTGCCAAGCCTGAGAATCGCGATCATCCGTGCACGGAATGTGACAAAGTGTTCCGTTGCCCTACTGCTCTAAAAAAACACATGTATAAGCACACTGGCGAGGAACTGCCGATTTCCTGTAACATCTGCAACAAACGCTTTCACATAAACAGCGATCTCCGAGATCATCTCTTGCGCCATGCCGGTGTAAAGAATCATGTGTGCCTCTACTGCGGCGTTGGTAAAACTACTCGACAGGAGTGGAACAAACACATTCTGACCCACACCAAGGAAAAGCAGTTCCAGTGTCGCCAGTGCGATCATGCTTCCCATAACAAACAGGCTTTGTCCAATCACGTCAAGGTGGTGCACATGAAGATCAAGAACTTTGCCTGCCAATATTGCGGCAAGACCTTTGGAAAATCGCATGCCTGCAAGATCCACGAAAGACTCCACACTGGCGAAAACTGTTGCGAGTGCAAGATCTGTGGAAAAATCTTTCTTTTCGAAAAGAGATTAACCAAACATTTGCAGATCCATGAGAAACGTGATGTACTGCCTCCTGCGACCAGTGTTAGGCCACAGGACAAGGAAAATCCGACAAATGTGGACCAGCAGTCAACTGAGCCAAAGGATGCGATGCTCATGATAGCAGTCCCCAAGCCGAAAAATTCGCATCGTGTTGAACGTGTGGATATATCACAACTGGCTGGCACTTCTGTAAATCCAATATCATCTGTATCGGTGCCCTCGTGGTCGCCGCAAGTGAATTTCACGAAGAAGGAAGGCCAGCACATTTGTCCCGGCTGTGGACGGGGCTTCAATCACATTGGCAATATGAAACTGCACTATAAAGTGATACACGAAAAGATCAAGGATTTCGCTTGTCGCTTCTGCCCCAAGCGCTTTGGCAAGGCTCAATATCTTCGGCATCATGAATATACGCATACTGGTGAGAGGCCCTACGGCTGTAAGATATGCGATAAGCATTTTAGCCATGGGTCATCCCTTAGGAAGCATATGATTTCACACAACAGACCGCCAAAGACCCCAAAGGCAATAAAGGTTCCCAAGACAAAGTCGGAGCAGCAGAGGCTAAAAATTGAGCTGAACAAGCGTCCGCCAAGAAACTATGAACAGTACCAGGATCCAGCTGCAGAACGGGCTGCAGCCACCGCTGAGTTGCTTGCCCAGCAGCTCGAGGAGGGTGAATCCAAGCGAAAGGCAGAGGCCAAGGCTCGGACTATTCAAGAGGCTGCCTGCGAGCAGCTTCAGAAACTGCAGAAGGAGCAGATGTTCGAAAAGATATCCTGTGATAGCTTTCAAGTACAATGCGTGGATGCGCTTAAAGctgataatatataa
Protein Sequence: MNEGSQTSIHAICRTCLSSLQHVAAHDLFVVPGLAKKLCVCTSLSVEQHDGFPKNLCPSCYTRLNDLHDFQQICMDSVQKLKDLLARNHFRIHTNEVDSFDVLSVVAPQDADVPVEEDDNINFDPLLNTKIEIFENEEDVFKMLEDVDKEAEQVDIEKESSTGSENGNYDAEENNSDSDDTLPLSRLRSTTTEAKPNNDDDDCRSGSEADANAEDKTTGKLKSKRIPAAERELRQLIDCHICHQKFKKAIRYEEHMKHHNDLLPFQCTVETCKKGFTTAAGLRHHVDHAHSELCELHACTVEGCDQAFPRTRMLTHHLKKVHNIAKPENRDHPCTECDKVFRCPTALKKHMYKHTGEELPISCNICNKRFHINSDLRDHLLRHAGVKNHVCLYCGVGKTTRQEWNKHILTHTKEKQFQCRQCDHASHNKQALSNHVKVVHMKIKNFACQYCGKTFGKSHACKIHERLHTGENCCECKICGKIFLFEKRLTKHLQIHEKRDVLPPATSVRPQDKENPTNVDQQSTEPKDAMLMIAVPKPKNSHRVERVDISQLAGTSVNPISSVSVPSWSPQVNFTKKEGQHICPGCGRGFNHIGNMKLHYKVIHEKIKDFACRFCPKRFGKAQYLRHHEYTHTGERPYGCKICDKHFSHGSSLRKHMISHNRPPKTPKAIKVPKTKSEQQRLKIELNKRPPRNYEQYQDPAAERAAATAELLAQQLEEGESKRKAEAKARTIQEAACEQLQKLQKEQMFEKISCDSFQVQCVDALKADNI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00499101;
90% Identity: iTF_00542659;
80% Identity: -