Basic Information

Insect: Drosophila kambysellisi
Gene Symbol: Bcl11b
Assembly: GCA_035042185.1
Location: JAWNLS010000438.1:1598125-1616318[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.028 1.9 9.1 2.4 1 23 315 338 315 338 0.95

2 6 7.8e-07 5.4e-05 23.5 1.5 1 23 787 809 787 809 0.99

3 6 0.013 0.9 10.2 4.7 1 23 815 837 815 837 0.99

4 6 1.2e-06 8.4e-05 22.9 3.2 2 23 1114 1135 1113 1135 0.97

5 6 1.6e-05 0.0011 19.3 3.3 1 23 1141 1163 1141 1163 0.99

6 6 2.9e-05 0.002 18.5 0.4 1 22 1171 1192 1171 1192 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.028	1.9	9.1	2.4	1	23	315	338	315	338	0.95
2	6	7.8e-07	5.4e-05	23.5	1.5	1	23	787	809	787	809	0.99
3	6	0.013	0.9	10.2	4.7	1	23	815	837	815	837	0.99
4	6	1.2e-06	8.4e-05	22.9	3.2	2	23	1114	1135	1113	1135	0.97
5	6	1.6e-05	0.0011	19.3	3.3	1	23	1141	1163	1141	1163	0.99
6	6	2.9e-05	0.002	18.5	0.4	1	22	1171	1192	1171	1192	0.97

Sequence Information

Coding Sequence: atgtacaacaaaatgCTGTCGATCAGTGAGGATCACGGATTCCGTTCGCTGAGCCATTCCGACTCGACAGAGAACGATGCGGTCGCCGCGCAGGACATCCTCACGTGCGGCGCCTGCCAGAAGACCTTCGCACTGTCGGACATTGTCCGCTTTATTCAGCACAAGGTGCTGCAGTGCAACAAGGAGAACTATGGCCAGTGCACCACACAAGCGCCCAGCATGGATCGCGATGCCGACGAGGGTCGACCCCTCAGTCTGGTCAATCGCCGTCCCTCGATATCGGCGCCAATCACAGGCCGCAAATCGGCGCCAGTTGCCGGCAGTGGGGCGACAGTTGCTGCCAATGCAATGGCCAGTgcggctgctgccactgctgccgctgcggcggcggcgacggcaGCGGCTGCCGCAGCCGCTGTTGCAAGCAGCGCTGCAAGCGGctcacgcatacacacaccgCCGCCGAGTCCAGCGGATCTGCTCGCCGATGGCGCCAGCAGCACTCCCAAGCGCCTCGTCGATGAGAACGACAATACGACGCCCAAGGCGGACAGCGATACGCTGAGCAGTGCCAACGGCGCAGCGGGTCTGGAGTCGAGCATCGCTCACAGTCCACGCGCTCAGCTGGCGCAGGGGCAACTGATTGGTCGGGAGGAGTGCGCTCTGCACGATGACAAGCCAAAGGTCAAGCAGGAGCCGTATGCCGACGACGAGCAGCTCGACGaagaactggagctggagcaggcACCAGAACGGGTGCGCGATGGGGAACACGATGGGGAGCACGAGcacgagcaggagcaggaacgggaacgggaactgAATGCGCAACTGCTGACACAGGCGACCGACAGAGACGAGTGCCAACAGCCGCTGGCCAAGCGGCCCAAAATGGAGCTCGTCGATGCCGAGGCGAACACGGTGCACACAGAGCCCAGCAATTACACATGTTCGACGTGCAAGACCCGTTACACATCCGCGTGGCGCCTCATCCAGCACGTGCAGCACTCGCACGGCGTCAAGATCTACGTGGAGACGGGTGGCTGTGGCGCCACCTTGACTGTGGCCACACCCGCCGCACTCAAtgcggcggcaacagcagcagcagcacaagccACCAGCATCAGCGTCAGTCCAAATCGCAGTCTCAGtcccacagcagcagcaactgttggtAGCGtctcgctgccgctgccgctgcacgCGCTCATGTCGCAGTCGCCGGCACcaaagcgcagcagcagcaacagcagcgccgccgccgccgccgcagcagcagcagccgcaatttCTGCAGGCTCGGCCAatacgagcagcagcagcagcagcaatgtcagcagcagcagcaacagcgccaATTCACCCacacagcaactgttgcagcaacgtgtacaacagcagcagcagcagcaacagcaacagcaacaacagcagcagcagcaacagcagcagcaacagagtcTAGCGCTGGCAGCAGGCATGCGTCATCATGCGCTGCTGGCGCCACCGGATTCGTTGCACGCGAACCCCTTCCAGCTGCTGCGCATGCCACTGCCACCCGCGCTGTCGCAGAGCAACGTAGTTCCTAGCGTGTCGCCGCTGTTTGGCCGCCCCACGCCCGCCGATCACTATCGCATGGAGCAGCTGGTTAGCGAGCAGTTCCGGCACCACGGCTTCAGCCtggccgccgccgctgccgctgcccagGCGCAATTCAATGccaacacacagcaacagcaacaacagcaacagcagcagcagcagcaacctgCTCAGCCGATTGCTGTCAATGTTCCTAATCCCGTCGAGCAGCGACCGCCAtcgagcaacagcagccagcgtGGCTCAGTACCGCCCGCTGCACTGCCGCCTCCGTCGCTCAgctcacagcagcagcagcagcaacaacaacagcagcagcagcaacagcagcagcaacaacagcaacagcagcagcaacaacagcagcagcaacaacaacaacagcaacagcagcaacaagtggctgcagcggctgctgctgctgctgcggcagctgcacTGAGTCCAGCTGCCAGTTTAAATTTGGAACCGCAGCAGATGGATTTTTACTCGCAGCGATTGCGTCAGCTTGCGGGCACAACAAGCCCTGGAGCTGGCAACATTGTTAACTCGAGCTCGCCGAGTCCACGACAGAAACAATCGCCGCGCTTTGCGAGCCCCTCGCCCAGCTCTGCCTCGCTTTCGGTGGCCGCTGCCACAACGCCGCCAGAGAAAGGTATCGAGAATGGCCAGCTAACGTCGACGCCCCGTTCCGCCagcacgcccacgcccaccaAGCCAGACACCGAACGGGAATCGGAGCTGGAGTCGAGCTGCTACTCGTGCGGCTACTGCGACAAGAAGTTCCGCTACGAGAACAACTTGATCATCCACCAGCGGACGCACACCGGCGAGAAGCCGTATAAATGCACCGCATGCGATTTTGAGTGCTCGCACATACAGAAGCTAATGAAGCATATGCGGGTGCATCGCAGTCCGGCCGATCAGGGACACGATGGCGGCGACAATCAGGATGGCCACGATGGCGGCAGCAATGCCGATTCGCTGGAAACGAATGAGGCGGACAACGATGATGATCCCAATCCCGATGAGTCCGACGAAGAGCTAAACGACGAGGATGCCGACGCGGATGCCGATGGCGAGGATGATGACGAGGATGAGCTGGACGATTGCGATGATGTTGACTACGAGGCCGAAGATCTGAGCGTCAACAATCGCATCGATGGCAAAAGTCAAAGCCCAAAGACGACCAGCTCCGGTGCCACATCGCTGGTGGGTGAGCTGATGGACAAGTTCGGGCTGTCCAATATTGCCCAATATTCGGAGGCGTACAAGCAGGCGCTGCAGGAGTCCGGACGCAAGGAGGCAGCCGCTGTGgccgcagccgctgctgccgccgccgccgttgtcgacaacaacaatcgcgGCTCGGCGGCCGGTGGCGCCAATCCGGGCGCTGCTGGCGGCGTTGCCTCCGCCCAGCCACTGGGTGACAAGCTTAACGGTTTGCCGGTGGCAGCGTTGCGACTGCGCGATGAGTTCGCCAAAAACTGTAATATGTTCCAGCCACAGCCGCAGGATGCGCCGTCGCAGGTGCCGCTCTTCAATCCGTTTCCCAACCCCTTCGAGCTGTCCAAGCGCATGAAGATCGATGGCGGCGATTGGTGGGGCATGTCCGCCCTGCATCGCAACGAGGCGCTCTTCGAGAACCTCAAGCTGAAGCCGTTGGGTTTGGGTGGCGCCAACTCGCTGTTGCAAGGACCGCTGCTCAAAAAGGAGAGCCGGCAGCGCAACGATACCTGCGAGTTCTGTGGCAAGGTGTTCAAGAACTGTTCCAATCTAACGGTGCATCGACGCAGCCACACCGGCGAGAAGCCATACAAGTGTGAACTGTGCTCCTATGCCTGCGCCCAGAGCTCCAAGCTCACGCGCCACATGAAGACGCACGGACGCACCGGCAAGGATGTGTACCGCTGTCGCTTCTGCGACATGCCCTTCAGCGTCCCCTCCACCCTCGAGAAGCACATGCGCAAGTGTGTCGTCAACCAGGGcaaggcggcagcagctgctgcaaatgcaGCCAATGCGGTTGCCGCTGCCCAAGCGGCCGCTGCCGCACAGCAACTGCAGGCCGCGGCACaggcacaacagcagcagcaacagcagcagcagcaacagcagcaacagttgccatcGCAATCGCAGTTATCGCCGCCTTGTGCAATGGGCGTGGCTGTCGGCTATCCGCCACAATTCGGACACAATCTGTCGCTGGCGGGCAGCCCACATCCGCATGTGCTGCTACCACCGGTACACCCACAATCGCATCCgcaccaccatcaccatcaccaccaacagcagcagcagcagcagcagcagcaacaacagcagcagcaacaactgcagcagcagcagcatccacacCACCATCCACAGTTGGCCAGCAGCCGCAGTCGCCTCATGTCGCGCATCTTCTAA
Protein Sequence: MYNKMLSISEDHGFRSLSHSDSTENDAVAAQDILTCGACQKTFALSDIVRFIQHKVLQCNKENYGQCTTQAPSMDRDADEGRPLSLVNRRPSISAPITGRKSAPVAGSGATVAANAMASAAAATAAAAAAATAAAAAAAVASSAASGSRIHTPPPSPADLLADGASSTPKRLVDENDNTTPKADSDTLSSANGAAGLESSIAHSPRAQLAQGQLIGREECALHDDKPKVKQEPYADDEQLDEELELEQAPERVRDGEHDGEHEHEQEQERERELNAQLLTQATDRDECQQPLAKRPKMELVDAEANTVHTEPSNYTCSTCKTRYTSAWRLIQHVQHSHGVKIYVETGGCGATLTVATPAALNAAATAAAAQATSISVSPNRSLSPTAAATVGSVSLPLPLHALMSQSPAPKRSSSNSSAAAAAAAAAAAISAGSANTSSSSSSNVSSSSNSANSPTQQLLQQRVQQQQQQQQQQQQQQQQQQQQQQSLALAAGMRHHALLAPPDSLHANPFQLLRMPLPPALSQSNVVPSVSPLFGRPTPADHYRMEQLVSEQFRHHGFSLAAAAAAAQAQFNANTQQQQQQQQQQQQQPAQPIAVNVPNPVEQRPPSSNSSQRGSVPPAALPPPSLSSQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAAAAAAAAALSPAASLNLEPQQMDFYSQRLRQLAGTTSPGAGNIVNSSSPSPRQKQSPRFASPSPSSASLSVAAATTPPEKGIENGQLTSTPRSASTPTPTKPDTERESELESSCYSCGYCDKKFRYENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVHRSPADQGHDGGDNQDGHDGGSNADSLETNEADNDDDPNPDESDEELNDEDADADADGEDDDEDELDDCDDVDYEAEDLSVNNRIDGKSQSPKTTSSGATSLVGELMDKFGLSNIAQYSEAYKQALQESGRKEAAAVAAAAAAAAAVVDNNNRGSAAGGANPGAAGGVASAQPLGDKLNGLPVAALRLRDEFAKNCNMFQPQPQDAPSQVPLFNPFPNPFELSKRMKIDGGDWWGMSALHRNEALFENLKLKPLGLGGANSLLQGPLLKKESRQRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMRKCVVNQGKAAAAAANAANAVAAAQAAAAAQQLQAAAQAQQQQQQQQQQQQQQLPSQSQLSPPCAMGVAVGYPPQFGHNLSLAGSPHPHVLLPPVHPQSHPHHHHHHHQQQQQQQQQQQQQQQQLQQQQHPHHHPQLASSRSRLMSRIF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00616427;
90% Identity: iTF_00558986;
80% Identity: -