Basic Information

Insect: Drosophila kambysellisi
Gene Symbol: esg
Assembly: GCA_035042185.1
Location: JAWNLS010000720.1:2297262-2299052[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 2.4e-05 0.0017 18.8 2.6 1 23 279 301 279 301 0.99

2 6 5.6e-06 0.00039 20.8 4.1 1 23 355 377 355 377 0.97

3 6 3.9e-06 0.00027 21.3 0.6 1 23 390 412 390 412 0.98

4 6 3.5e-08 2.4e-06 27.7 0.4 1 23 416 438 416 438 0.97

5 6 3.9e-08 2.7e-06 27.6 2.1 1 23 444 466 444 466 0.98

6 6 1.1e-05 0.00074 19.9 0.4 1 22 472 493 472 493 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	2.4e-05	0.0017	18.8	2.6	1	23	279	301	279	301	0.99
2	6	5.6e-06	0.00039	20.8	4.1	1	23	355	377	355	377	0.97
3	6	3.9e-06	0.00027	21.3	0.6	1	23	390	412	390	412	0.98
4	6	3.5e-08	2.4e-06	27.7	0.4	1	23	416	438	416	438	0.97
5	6	3.9e-08	2.7e-06	27.6	2.1	1	23	444	466	444	466	0.98
6	6	1.1e-05	0.00074	19.9	0.4	1	22	472	493	472	493	0.96

Sequence Information

Coding Sequence: ATGGATAAACTCAAGTACAGCAAATGTCCGCTGAAAAAGCGACCCATACTCGTCGAGGAGCCGCCACATGAGGATCAGCTGTGTCATGATGAGGGACCCGTTGATCTTAGCGTGGCGTCCGCTGCGGTGCCTCTAGAGCCTACACATTGGTCCATCAAAACGGTGCCGACACCACAGCCGGTGCCGCAAGAGCTGCGTCGTCGCTTCGATGCAGCCATGACACAGACCAAGGATCAACTGGCCCGGCGCATTTGGGAGGAGACACGAGAGATTGCTCGCGCGTTTCCGGATGTGTTTACGCGCGAGGAGATTGCTAAAAGTCTGGCCCGTCTCGGCTATGGTGACTTCGAGCTGCCGCCCGAGGATGAGGTCATGCAGCCAGAGCAGCAGCGGGACTTGGAAATGACTGCTAGCTATGCACGCATTTCGCCACCTTTGGTGCCCACCTCAATCGTTAAAGTGGAGCACACGGAAGAGCCTTTTGGTCTGCGCaactacaataacaatttgctGAAGAGCATTGCGGAGTATGAGGATTGCATGAAGATGCCaatgccaccgccgccaccacctcctccagcagagccaCAGGATTTGAGTGTGACGCCACAGCAGCGTCGGGGCTTGAGTGAGAATGTCAATCTGCACAATGTGGCACGAGCGCTGCTCAGCATGCAACACATAGCgccacagcagccgcagcagcagttgcccgAACAGATCTTCAAGTCTGCTCCAGTCCATCAGGTCGAGCAGGATGAGGATGACTTGGAGAACCAGGAGAACAGCGAAAATCAGCTGAATTTGAAGATCAAGAGCAGCAACGATTTGTACTATCAGTGCCAACAGTGCAACAAATGTTATGCCACCTACGCGGGTCTCGTCAAGCACCAGCAGAGTCACGCCTACGAGAGCACCGAGTACAAGATTATACGCAGCAATCCCAGTGGTGGTCCCATTGTCGATCAAACTGAATTCTGCACCGATCAGGCATCGGCACTCATCCAAGCGGCGAATGTTGCCTCAGCACAATCGATGCAGAAGCCGGTGGGTGTGCCACGATATCATTGCAAGGATTGCGGCAAGTCCTATTCCACCTACTCTGGCCTGAGCAAGCATCAGCAGTTCCACTGCCCCTCGGCCGAGGGCAATCAGGTGAAGAAAGTCTTCAGTTGCAAGAACTGTGAGAAGACCTACGTCTCGCTGGGAGCGCTCAAGATGCACATACGCACCCACACCCTGCCCTGCAAGTGCCCCATCTGTGGCAAGGCCTTTTCCCGCCCCTGGCTGCTTCAGGGTCACATACGCACCCACACGGGCGAGAAGCCCTTCAGCTGCCAGCATTGCAACCGCGCCTTTGCGGATCGCTCCAATCTGAGGGCGCACATGCAAACGCACTCGGATGTGAAGAAGTACTCCTGCCCCAGCTGCACCAAGTCATTCTCTCGAATGTCGCTCCTGGCCAAACACTTGCAGACCGGCTGCCAGACGGAGCAGGGTGGTTCATCAGCAggcgtagcagcagcagcagcagccgggttcaatcagcagcagctgcagcagcatctgcaggACTACGATGAGATGGCGCCTCATCCCCTCTACTATGCGGGTAGCgtgggcagcagcggcggggaggaggaggaggcacaCGAATTTCAAATGTCCACACAGGTCAGACGGGGCATATACTAA
Protein Sequence: MDKLKYSKCPLKKRPILVEEPPHEDQLCHDEGPVDLSVASAAVPLEPTHWSIKTVPTPQPVPQELRRRFDAAMTQTKDQLARRIWEETREIARAFPDVFTREEIAKSLARLGYGDFELPPEDEVMQPEQQRDLEMTASYARISPPLVPTSIVKVEHTEEPFGLRNYNNNLLKSIAEYEDCMKMPMPPPPPPPPAEPQDLSVTPQQRRGLSENVNLHNVARALLSMQHIAPQQPQQQLPEQIFKSAPVHQVEQDEDDLENQENSENQLNLKIKSSNDLYYQCQQCNKCYATYAGLVKHQQSHAYESTEYKIIRSNPSGGPIVDQTEFCTDQASALIQAANVASAQSMQKPVGVPRYHCKDCGKSYSTYSGLSKHQQFHCPSAEGNQVKKVFSCKNCEKTYVSLGALKMHIRTHTLPCKCPICGKAFSRPWLLQGHIRTHTGEKPFSCQHCNRAFADRSNLRAHMQTHSDVKKYSCPSCTKSFSRMSLLAKHLQTGCQTEQGGSSAGVAAAAAAGFNQQQLQQHLQDYDEMAPHPLYYAGSVGSSGGEEEEAHEFQMSTQVRRGIY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00803790;
90% Identity: iTF_00570557;
80% Identity: -