Basic Information

Insect: Drosophila kambysellisi
Gene Symbol: -
Assembly: GCA_035042185.1
Location: JAWNLS010000720.1:719182-720921[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 5.3e-07 3.7e-05 24.0 4.3 1 23 267 289 267 289 0.97

2 11 0.00013 0.0089 16.5 5.9 1 23 295 317 295 317 0.99

3 11 4.7e-05 0.0033 17.9 1.6 1 23 323 345 323 345 0.97

4 11 9.2e-06 0.00064 20.1 5.1 1 23 351 373 351 373 0.98

5 11 8e-07 5.6e-05 23.4 0.8 1 23 379 401 379 401 0.98

6 11 8.9e-07 6.2e-05 23.3 4.6 1 23 409 431 409 431 0.98

7 11 7.8e-06 0.00055 20.3 0.9 1 23 437 459 437 459 0.99

8 11 2.2e-05 0.0015 18.9 6.3 1 23 465 487 465 487 0.98

9 11 0.00025 0.018 15.6 0.1 1 23 493 515 493 515 0.98

10 11 4.5e-07 3.2e-05 24.2 0.8 1 23 521 543 521 543 0.98

11 11 5.8e-06 0.00041 20.7 2.8 1 23 549 571 549 571 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	5.3e-07	3.7e-05	24.0	4.3	1	23	267	289	267	289	0.97
2	11	0.00013	0.0089	16.5	5.9	1	23	295	317	295	317	0.99
3	11	4.7e-05	0.0033	17.9	1.6	1	23	323	345	323	345	0.97
4	11	9.2e-06	0.00064	20.1	5.1	1	23	351	373	351	373	0.98
5	11	8e-07	5.6e-05	23.4	0.8	1	23	379	401	379	401	0.98
6	11	8.9e-07	6.2e-05	23.3	4.6	1	23	409	431	409	431	0.98
7	11	7.8e-06	0.00055	20.3	0.9	1	23	437	459	437	459	0.99
8	11	2.2e-05	0.0015	18.9	6.3	1	23	465	487	465	487	0.98
9	11	0.00025	0.018	15.6	0.1	1	23	493	515	493	515	0.98
10	11	4.5e-07	3.2e-05	24.2	0.8	1	23	521	543	521	543	0.98
11	11	5.8e-06	0.00041	20.7	2.8	1	23	549	571	549	571	0.98

Sequence Information

Coding Sequence: ATGGAACAAGTTTGCTATGCATGCAAAATCAGCTCCTGCAGCCTGGTGAATATATTCACAGAGGGACAGCCCAGTCTGGCGGAGATGTTGAGCGAGTGTGTTGCCTATGTAATTAATCGAAATGATGCGCTTCCTCAGCAGCTGTGCGTCTCCTGCATCAGCGCTGCAAAAATTGCGTTTCGCTTGAAGCGCAACTTCGAAcagaaaaaaccaaaaacaaatgcttGCCGCATTTGCAGAAGCAGCTCAATTACTTTAATTGAGATCGATGcaaagcggcagcagccacGGGGAGAACCCTGTCTAGCGGAAATGATAAAAGAGTGCGTTGGCTATCGGACAAATTCCAGCGATCAGGTATGCCTGTCGTGTATTCTGAGCGTTGAAAGCGCCTTTCAATTCAAGCGGCGATGCGAGCAGAGCCATCAGCTGATTGAAAGTAAAGTTGTTGAACATGTGCTTTCTCATAACAGCTTACAAATGGAGCAACaagattataatataaaaatcgaaTTCAATGAAAATGACTTTGAATGCGGTCAGACTCGCATTATGTTGGAGGAGCAAAAGTCTGAAGAGCAATCGGAAGTGATTACCATGCCAGTTTATAATCATGTCCAATCAGAGACTGAAGTGGATGCAATGAAGAAACAAGTCAGCGATAATGAAAAAGACTTTGAATGCGATCAGACTCGCATTATGTTGGAAGAGCAGAAGTGTGAAGAGCAATCGAAAGTGATTACCACGCCAGTCAATCATCATTTCCTATCAGAGATTGAAGTGAATGCAAAGAAGAAACACATGTGTGAGATGTGTGGCAAAACGTTTTCGACCACTAGTCATCTGACTGTGCACAGACGCATCCATTCTGGCGAACGTCCGTTCAAGTGTTGCCAGTGCACAAAGGATTTTACAAGTCGCAAAGTGCTCAAGGATCACATGCGCACACATACAGGCGAACGGCCATTTCACTGTGCCCAGTGTCCCAAGTCATTTGGCCGGAATAATGCTCTGGTTAAGCACATGTTCTCGCATACGGGCGAACGGCCCTTCAAGTGCAGCCACTGCCCGAAAGGCTTCTATCAGAGATCACATTTAAATATCCATAATCGCATTCATACTGGGGAGCAGCCATATAAATGTCCCCATTGCCCTCGGGCCTTTCCACGCAAGGAGTATCTAGCGACGCACCAGCTACTGCATGCCACTGCGGGCGAGCATCCACACCAGTGTCCCCACTGTTCCAAGACCTTTTCCCGCAGCAAAAACTTAGAGATACACTTGACCATGCATACCGGTAAGCAGCCCTATCGGTGTCCCCATTGCATCAAGGTGTTCACCGCCAATGCCAATCTACAAATGCATATCCGGAGTCACACGGGCGAACGTCCGCACAAGTGTCCCCACTGTGCGAAGACATTCAACCAGAGCGTCTGCCTCAAGAATCACATACGCATTCACACCGGCGAACGACCCTTCCAGTGTGCCCAATGTCCGAAGGCTTTCGCCAGCACTGGTGGACTGTACAGTCACAGTCGAGTCCACTCCGGCGAACGTCCCTTCCAGTGTCCCCAGTGCCCGAGACGATTTCAGCGCAACGAGAATCTGCGCAATCACATTAATCTCCACTCCGAGGATTCCCCGTTCAAGTGCAGCCTGTGTCCCAAGCACTTTACACGCCGCGAGAGTCTGGCCAGGCACAAGCTGATTCATGCAAAAAAGGAAATACcgaaaaattaa
Protein Sequence: MEQVCYACKISSCSLVNIFTEGQPSLAEMLSECVAYVINRNDALPQQLCVSCISAAKIAFRLKRNFEQKKPKTNACRICRSSSITLIEIDAKRQQPRGEPCLAEMIKECVGYRTNSSDQVCLSCILSVESAFQFKRRCEQSHQLIESKVVEHVLSHNSLQMEQQDYNIKIEFNENDFECGQTRIMLEEQKSEEQSEVITMPVYNHVQSETEVDAMKKQVSDNEKDFECDQTRIMLEEQKCEEQSKVITTPVNHHFLSEIEVNAKKKHMCEMCGKTFSTTSHLTVHRRIHSGERPFKCCQCTKDFTSRKVLKDHMRTHTGERPFHCAQCPKSFGRNNALVKHMFSHTGERPFKCSHCPKGFYQRSHLNIHNRIHTGEQPYKCPHCPRAFPRKEYLATHQLLHATAGEHPHQCPHCSKTFSRSKNLEIHLTMHTGKQPYRCPHCIKVFTANANLQMHIRSHTGERPHKCPHCAKTFNQSVCLKNHIRIHTGERPFQCAQCPKAFASTGGLYSHSRVHSGERPFQCPQCPRRFQRNENLRNHINLHSEDSPFKCSLCPKHFTRRESLARHKLIHAKKEIPKN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00522347;
90% Identity: iTF_00522347;
80% Identity: -