Basic Information

Insect: Drosophila jambulina
Gene Symbol: esg
Assembly: GCA_018152175.1
Location: JAECXH010000114.1:6393829-6395943[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 6.5e-06 0.00047 20.3 3.7 1 23 276 298 276 298 0.99

2 6 6.6e-06 0.00048 20.3 3.7 1 23 353 375 353 375 0.97

3 6 9.3e-07 6.8e-05 23.0 0.6 1 23 388 410 388 410 0.98

4 6 2.9e-08 2.1e-06 27.7 0.4 1 23 414 436 414 436 0.97

5 6 3.3e-08 2.4e-06 27.6 2.1 1 23 442 464 442 464 0.98

6 6 4.4e-06 0.00032 20.9 0.4 1 21 470 490 470 491 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	6.5e-06	0.00047	20.3	3.7	1	23	276	298	276	298	0.99
2	6	6.6e-06	0.00048	20.3	3.7	1	23	353	375	353	375	0.97
3	6	9.3e-07	6.8e-05	23.0	0.6	1	23	388	410	388	410	0.98
4	6	2.9e-08	2.1e-06	27.7	0.4	1	23	414	436	414	436	0.97
5	6	3.3e-08	2.4e-06	27.6	2.1	1	23	442	464	442	464	0.98
6	6	4.4e-06	0.00032	20.9	0.4	1	21	470	490	470	491	0.95

Sequence Information

Coding Sequence: ATGGATAAACTCAAGTACAGCCGCTGTCCGCTCAAGAAGCGTCCGATAATGGTGGAGGAGTCCTATCAGGAGGATCACCTAAGTCACGACGAAGGACCCGTGGACTTGAGTGTAGCCTCGGCAGCTGTTCCCCTCGAACCTCATTGGTCGGCGAAAGCGGAACCGGAACCGCAGGCCGTGCCCCCGGAGCTGAGGCGTCGCTTCGATGCGGCCATGAATCAGACCAAGGAGCAGCTGGCCCGCCGCATCTGGGAGGAGACCCGGGAGATAGCCCGTGCCTTTCCCGATGTCTTTACCCGCGAAGAGATCGCCAAGAGCCTGGCGCGCTTGGGTTACGGGGAATTCGAGCTGCCACCGGAGGAGGAGGTCATGGAACCCGAACCAGAGCCAGAACCCCAACCCGAGCCAGAGCAACAAATTCCGCTGAGCTATGCCAGGGAGTCACCTCCCACAGTAATCAAAGTAGAGCCCACCGAGCAGGACTTTCCGCTGCGGAACTACAACAATAATCTGCTCAAGAGCATAGCGGAGTACGAGGATTACATGAAGATGCAACCCATCAAGGAGGAGCTGGTGCCAGTGCCCCAGCCTCCGATGTACTATCCGCCGCCCACTCCTCTAGCCGAGCCCGAGGATCTCTCGGTGACCCAGAGGCGGGTGCTCAGCGAGAACATGAATCTGCAGAATGTGGCCAGGGCTCTGCTCAGCATGCAGCACATGGCGCCGCATCCACAGCAGCATCCTCTGCCGCCACAGGACATGGAGGAGGACCAGGAGAACCAGGACCTCAATCCGCTGAAGATCAAGAGCAGCAACGACCTGTACTACCAGTGCCAGCAGTGCAACAAGTGCTACTCCACCTATGCCGGCCTGGTGAAGCACCAGCAGACCCACGCCTACGAAAGCACCGAGTACAAGATCATCCGGAGTCAGCCGGGTGGCTCAGGCCCCATTGTGGACCAGACGGAGTTCTGCACGGATCAGGCCTCGGCTCTGATCCAGGCAGCCAATGCTGCCTCGGCGCAGAGCATGCAGAAGCCGGTGGGCGTGCCCAGGTACCATTGCCAGGACTGCGGCAAGAGCTACTCCACCTACTCCGGCCTCTCCAAGCACCAGCAGTTCCACTGTCCCTCGGCGGAGGGCAACCAGGTGAAGAAGGTGTTCAGCTGCAAGAACTGCGACAAGACATACGTTTCCCTGGGCGCCCTGAAGATGCATATTCGCACCCACACGCTGCCCTGCAAGTGCCCCATCTGCGGCAAGGCCTTCTCGCGACCCTGGCTCCTCCAGGGACACATCCGCACCCACACGGGCGAGAAGCCCTTCAGCTGCCAGCACTGCAATAGGGCCTTTGCTGACCGCTCCAACCTGCGGGCTCACATGCAGACCCACTCGGATGTGAAGAAGTACTCCTGCCCCACCTGCACCAAGTCCTTCTCCCGGATGTCCCTGCTGGCCAAGCACCTGCAGAGTGGCTGCCAGAGCGAGCAGAACGGCGGAGCGGGAGGCTCCTCCGGCGGTGGCTTTGATCAGCAGCAGCTCCAGCAGCATCTCCAGGGCTACGAGGAGGGTCACCAGGTGTACTATGCGGGCAGCGTGGGCAGCAGCAACGGGGAGGAGGAGGAGGCCGGTGACTACCCCATGCCGCCGCCACCAGCCATATATTAA
Protein Sequence: MDKLKYSRCPLKKRPIMVEESYQEDHLSHDEGPVDLSVASAAVPLEPHWSAKAEPEPQAVPPELRRRFDAAMNQTKEQLARRIWEETREIARAFPDVFTREEIAKSLARLGYGEFELPPEEEVMEPEPEPEPQPEPEQQIPLSYARESPPTVIKVEPTEQDFPLRNYNNNLLKSIAEYEDYMKMQPIKEELVPVPQPPMYYPPPTPLAEPEDLSVTQRRVLSENMNLQNVARALLSMQHMAPHPQQHPLPPQDMEEDQENQDLNPLKIKSSNDLYYQCQQCNKCYSTYAGLVKHQQTHAYESTEYKIIRSQPGGSGPIVDQTEFCTDQASALIQAANAASAQSMQKPVGVPRYHCQDCGKSYSTYSGLSKHQQFHCPSAEGNQVKKVFSCKNCDKTYVSLGALKMHIRTHTLPCKCPICGKAFSRPWLLQGHIRTHTGEKPFSCQHCNRAFADRSNLRAHMQTHSDVKKYSCPTCTKSFSRMSLLAKHLQSGCQSEQNGGAGGSSGGGFDQQQLQQHLQGYEEGHQVYYAGSVGSSNGEEEEAGDYPMPPPPAIY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00486734;
90% Identity: iTF_00602776;
80% Identity: -