Basic Information

Insect: Drosophila insularis
Gene Symbol: -
Assembly: GCA_018903935.1
Location: JAEIFP010001084.1:9104257-9107648[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0059 0.46 11.1 1.3 1 23 68 90 68 90 0.94

2 8 0.0038 0.3 11.7 2.3 1 23 126 148 126 148 0.97

3 8 0.13 11 6.8 2.9 1 21 154 174 154 175 0.95

4 8 0.00077 0.06 13.8 1.4 3 23 498 519 496 519 0.95

5 8 1.5e-05 0.0011 19.3 1.2 1 23 599 621 599 621 0.97

6 8 6.1e-06 0.00048 20.5 4.2 1 23 627 649 627 649 0.99

7 8 0.00017 0.014 15.9 2.9 1 23 655 677 655 677 0.98

8 8 0.00056 0.044 14.3 0.1 1 21 683 703 683 704 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0059	0.46	11.1	1.3	1	23	68	90	68	90	0.94
2	8	0.0038	0.3	11.7	2.3	1	23	126	148	126	148	0.97
3	8	0.13	11	6.8	2.9	1	21	154	174	154	175	0.95
4	8	0.00077	0.06	13.8	1.4	3	23	498	519	496	519	0.95
5	8	1.5e-05	0.0011	19.3	1.2	1	23	599	621	599	621	0.97
6	8	6.1e-06	0.00048	20.5	4.2	1	23	627	649	627	649	0.99
7	8	0.00017	0.014	15.9	2.9	1	23	655	677	655	677	0.98
8	8	0.00056	0.044	14.3	0.1	1	21	683	703	683	704	0.96

Sequence Information

Coding Sequence: ATGGACATAGATAGTGCAAGGATGAAACAGGAGGTGGATGACGACATGGATGTGGATTTCAATAGCGTCAAAATCATAAAGGAGGCTACCAATATGATTACGGTGATTGCTAACGATCACAAATCGGAGGATGAGAGGAAGTTTATTGAAAGCTTGGCTAGCAGTAATCCTGATCAGTTATTCAGCGAATCATCTAAAAATTATTTATGCAAGTTTTGCCAAACCTCGTTCAGGACTCGTTTAGAGTTTGATGCGCACATGGTCAATCATAAAATGAATCGTCATTTTTGTCGTTTCGGCTGTTCATTTTGGTGCGATTCGTTGGAGCAAATTCTCGAACATGAATACAAAAATCATTCCCAGGGGTTGAAAAAATTTTGTTGCCGGGTCTGTGATTGTATTCTTCCCAATGCCAATGATCTTACAAAGCATATGCTAAGTCATGTCCACGGTCAACGTTATGTTTGTGCCTTGTGCCGCAGACATTTTGAGTCCCATCAAGGCTTGCAATTGCATCGTAAGCATAGCAAGGAAATTTGCGGTCAGGTTGAGTCCATAAATGGTGTCTCTCATCGCATCGAGCTGGTTGCTACTGCAGAAAAATGTCAATTACCAGCTGAGCTATTATGTGATGTTCAAATCAAAGAGGAACCCAAAGATTATGTTGATGAGCACGAAATTCGCATTAAGGAAGAACCCATGGATGAGGAAGAAGAATCTCCGCAGTTGACTGCAAGCATTAAACCCAATTTGGGCTTGGATTGGCGTAGTAAGTTGCGTTTGCCGGCCCTGAAGCCAAAGCCGGAACTAAAGCCCTTACCGCCCACCCAATCGAATTTAAAGATTGTCAATTGGAATAATCAATCGACCACAAATACTGCCATACTTAAAAGAGCAAATATATTGAAAACGAATTCAAACTCGAATTCAATTAACAACAACAAGAAACCTTTAATTGCTGATAATATATTACAAATGTTGCCCAGCAATTTTATGGTAATTAAACTTCCACCAAATACAAAAATTCTTAAATTACCACGAGAAGTGAATAAAACCACATTAAAACATTCCTCAATAACATCGCCAGCCAGTGTACAAATCACACAGGTTGTTAAACAAGATATTCAAAATATTAATTCATCTACTGCTGACTCAAACAATGGTAAAGTAGCATCATCTCCGCCAAGAAATAATAATCGCTTGGGGAGCTTTCACCATGAAGCCTTTTACGATTTGGAAAGTCGACCAGAGTCAAGGAAAATGATTGAAGAAATTCAAAATCAAATTCGTAGTATTGAGAGAACATTACCCATACCTGGCAGCGTATTGCAATCCAAAACAAGGAGATCTTTCTCCATAAATAACAACAGCCAGTCTACTGATGATATGAAAGATGAGCCCACTAAATTGGAATTATTACTAAATCCAGCATGCACCAATGTGTGGAAAACGCTTTTTGAAAAATATCCCAACTATTGCTTCTATTGGGCTTGTCCCATGTGCCCCACTTCCTGTGAACAGGCTAAAGATTTGCGCCATCATTTAAGCCGAATGCATAGGATGAGTGATGATAAATTGAATACCTTAAAGGTGACGCTACTACCAAAGAAAGTAGCCATAGATGAAGTGGAGCAAACAAAGCCATCGATTCAGACAGTGAAAACTTCGAAGGCTCCTCAAATGTCAGCAAATGCAACTCCAGTCAATGAAAATTCACAAGTGTCATCCCCTGAACCACAAACTTCGAAATCTTCAAATGTGCCAAAAGCAAAAGCAACAGGTTCGCAGCAGCAACATGAATGTAACGAATGTTCCAAGACGTATACCACATCGGGAGCTTTAAGGATTCATAAGATGATCCATACCGGTGAATTGCCCTATAAGTGTAATTTCTGTGACAAACGTTTTCGCACGCCGGGCCAGGTGAAAGTTCATCATCGTCGTCATACAGGAGAGAAGCCCTTTAAATGCAAGATCTGCTCATTGGATTTCACTCATCGCGAGACTCTTATTTCGCATCTTTCGCGTCACATTGGAATGAAACGTTACAAGTGCTACGGATGTGATAAATATTTTGTAGTTGTAAGCGGTCTGCGAGCTCATCGTCGCCTTCGTCCTGATACTTGTGGCAAGGTGAAATTTACAGCTCGTGCTCATGGTCCGCGGGTGCGTGTAATTAAGGGCGAGGTGATATTCGAGGGACATCCCGAGCACAATGGTTACTTGCGTAGTGAGGATCCATTGAAAATTCTGTCGGAAATGAATCAGACCGACACAATGACTGTCGAGGATGACGATAAGGCGGCCAAAGGCGTTTAA
Protein Sequence: MDIDSARMKQEVDDDMDVDFNSVKIIKEATNMITVIANDHKSEDERKFIESLASSNPDQLFSESSKNYLCKFCQTSFRTRLEFDAHMVNHKMNRHFCRFGCSFWCDSLEQILEHEYKNHSQGLKKFCCRVCDCILPNANDLTKHMLSHVHGQRYVCALCRRHFESHQGLQLHRKHSKEICGQVESINGVSHRIELVATAEKCQLPAELLCDVQIKEEPKDYVDEHEIRIKEEPMDEEEESPQLTASIKPNLGLDWRSKLRLPALKPKPELKPLPPTQSNLKIVNWNNQSTTNTAILKRANILKTNSNSNSINNNKKPLIADNILQMLPSNFMVIKLPPNTKILKLPREVNKTTLKHSSITSPASVQITQVVKQDIQNINSSTADSNNGKVASSPPRNNNRLGSFHHEAFYDLESRPESRKMIEEIQNQIRSIERTLPIPGSVLQSKTRRSFSINNNSQSTDDMKDEPTKLELLLNPACTNVWKTLFEKYPNYCFYWACPMCPTSCEQAKDLRHHLSRMHRMSDDKLNTLKVTLLPKKVAIDEVEQTKPSIQTVKTSKAPQMSANATPVNENSQVSSPEPQTSKSSNVPKAKATGSQQQHECNECSKTYTTSGALRIHKMIHTGELPYKCNFCDKRFRTPGQVKVHHRRHTGEKPFKCKICSLDFTHRETLISHLSRHIGMKRYKCYGCDKYFVVVSGLRAHRRLRPDTCGKVKFTARAHGPRVRVIKGEVIFEGHPEHNGYLRSEDPLKILSEMNQTDTMTVEDDDKAAKGV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00618661;
90% Identity: iTF_00612304; iTF_00618661;
80% Identity: -