Dins015128.1
Basic Information
- Insect
- Drosophila insularis
- Gene Symbol
- -
- Assembly
- GCA_018903935.1
- Location
- JAEIFP010000150.1:2426546-2429280[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.068 5.3 7.7 5.9 3 23 281 301 279 301 0.96 2 12 0.0012 0.092 13.3 0.5 1 23 307 332 307 332 0.94 3 12 0.003 0.24 12.0 1.1 1 23 339 364 339 364 0.95 4 12 0.00027 0.021 15.3 1.9 1 23 376 398 376 398 0.98 5 12 2.3e-06 0.00018 21.8 0.2 1 23 405 427 405 427 0.98 6 12 0.0066 0.52 10.9 0.1 1 23 433 455 433 455 0.98 7 12 0.0064 0.5 10.9 4.0 1 23 461 484 461 484 0.98 8 12 0.0087 0.69 10.5 3.9 1 23 490 512 490 512 0.96 9 12 0.00015 0.012 16.1 3.6 2 23 519 540 518 540 0.96 10 12 3.9e-05 0.0031 17.9 0.3 1 23 664 687 664 687 0.96 11 12 0.022 1.8 9.2 1.0 1 19 693 711 693 715 0.94 12 12 1.7e-06 0.00013 22.2 4.1 1 23 721 743 721 743 0.99
Sequence Information
- Coding Sequence
- ATGAATGAGGGGAGTGCGTACTCCATTCACTCGGTGTGCCGCATCTGTTTGAATCATTTGCAGAATGGTCCCGTTTTCGATCTATTCCTAATACCCGGACTGGCCAAGAAGCTGTGTGTGTGCACGTCGCTGTCGGTGGAACAGCAGGATGGATTCCCCCGCAATATATGCTGCACCTGCCACACCAAATTGGATGACATGCATCAGTTTCAGAAATTGTGCGTCGATTCGGTGCAGAGATTCCAAATGATGTTAAGCCAGAATATGTTTAGCAGCAGTTCCTCCTCCGCAACTTTTGATTTGATGAATGTGATGACTACCAGCCACACTGAAGGGCCGGCAGATGAACCACCACTTGTGGCTGGTGGTGGTGGTGGTGCCGCTACTGCTGGTGAGGAGGATGATCGCCTTAATTTTGATCCTTTGCTCAATCACAAAATGGAATTGATTGAAAACGAAGAAGACGTCTTCAAAATGCTCGAGAATGTCGATAAAGAAGTGGAAGATGTGGAGAAACAAGAGGAGGATGATGAAGCGGAAGATGATGACTTTGAAGAGGACGATGATAACGATGATCGTGATGCGGACTTTCAACCTCAATTAAGTAGCGATGCTGGCGACGATGATGACTTGCCTCTAGCTCAACGTTTGCGAATGAAAAAGAAACGATCTAAGAGAGTCAAAAAAGAAAAGGAGTTCCTCTCAGGCTCTGGAGAAGACTTCGATTATGATGATGGAGATGAGGATGGTGATGATGATGGTAATGAAGGTGACTTTAAATCAAAGGCTAAACGCAAGAGGATACCAGCCGATGAACGTCATTTGCATCGCATTATCGATTGCCACATTTGCCATCAGAAGTTCAAGAAAGCCATTCGCTATGAGGAGCACATGAAGCATCACAATGATCTACTACCCTTCCAATGTAAGGTGGAGACGTGTCGCAAGGGATTTACTACAGCCGGTGGCCTACGCCTGCACATAGACCATGCCCACACCGAGCTATCCGAGGTACATTCTTGTTCGGTCGAGGGATGCGGCAAAACCTTTCCTCGTGTCCGTCTACTAACCTTTCACATGAAGAAGGTCCACAACATATCAAAAGCGGCAGCTCCGCCAAGGGATTACCCATGCTCGGAATGCGAAAAGGTCTTCCGTTGTCCCATGGCCCTGAAGAAGCATATGTATAAGCATGATGGCAAAGAATTGCCCTTCCCCTGCAATATTTGTGGCAAGCGATTTGTCATCAATTCCGCCCTCAAGGACCATTTGATGCGCCATGCTGGAATCAAGAACTATGTGTGTCCCTATTGTGGTGTGGGCAAAACGACACGTCAAGAGTGGAATACTCATATCCTAACCCACACCCAGGAGAAGAAATTCAAGTGCCATATATGCGAACATGCTTCGCACAACAAACAGAGCCTGGCCAATCACATCAAGATTGTCCATGAGAAGATTAAGAATTATGCCTGTCAGTATTGTGGCAAGACCTTTGGCAAGTCGCATGCCTGTAAAATCCACGAGATGACCCATACGGGAGAGAAACGATGCGAGTGCAAGGTCTGTGGCAAGAAATTCCTTTATCCAAAGAGTCTAACAAAGCATTTAAAGACGCATGAGAAGCGCGTGCTCCGTGCCATCGAAACGTATCGTCAGCGTCAAGTGGAGATGGGAGAAACATCAGGTCAAGGCGATCAACAGCAACAGCAGCTGGATCAAGTCAACATTGGTCTGCCAAATCCCACGGGAAGTGTCACTGTGACTATAGCCGAACCTGGCGTGGGTGAACAATTAATGTCCCAGAATGCTGCCGATGAGTTGCTGAAAGTTTGTGCTGAATCTGTGGCCACCATACCCAAAGATCCGCGTCGTGTCCAGCGTGTGGACATCTCTCAGTTGGCAGGAACAGCGGTAAATCCCATATCCTCAGTCTCAGTGCCATCATGGTCACCCCAGACAACGAACTTTACGAAAAAGGAGGGCAAACACATTTGTCCAGGCTGTGGTCAAGGCTTCAATAATATTGGCAACATGAAGCGTCATTACAAGATCATTCACGAGAAGGTCAAAGATTTCGCCTGCCGCTTCTGCCCACGACGATTCGCCAAGGCCCAGACGCTCCGACATCACGAATGGATCCATACGGGCGAGAAGCCTTTCGAGTGTAAAACCTGTGGAACACATTTCCGCCAGGAGACCGCCCTGAAACGGCATCAGCGCACCCATGAGAATCGCCCGCCCGTCATCTCGTCCAAGTTCTATGCCGCTCGCGAGGAATTGGAAGAGCAGGAGCGCTCCAAACGCGAGGCCAAACGCAAGGCGGAGGCCAAACGTAAAGAGATCGCCGAAGCAGCCAAGGAGCAATTATCCACTTTGCATAAATTGGAGACCATTGACAAGCAATTGCATTCCTATGACGAGTATCAGGAGGCTGCCGCTGAGCGGGCAGCTGCCAGCGCTGAACTCCAGGCCCAACAGAACGAGGAGAACGAAGTCCGCCGACGGGCCGATGAGGAACGCATCAAAATTCAAGCGGCTGCCTATGAGCAGTTGCAAAAGCTGCAAGAGCAGCAGGAAATCGATAAGGCTCAAAGCTCCTATGATGGCTACTATGCTCAGAAGGCTAATGCCGATGGCACCAATTATGATGCTCTCAAAATTGATCATGTGTGA
- Protein Sequence
- MNEGSAYSIHSVCRICLNHLQNGPVFDLFLIPGLAKKLCVCTSLSVEQQDGFPRNICCTCHTKLDDMHQFQKLCVDSVQRFQMMLSQNMFSSSSSSATFDLMNVMTTSHTEGPADEPPLVAGGGGGAATAGEEDDRLNFDPLLNHKMELIENEEDVFKMLENVDKEVEDVEKQEEDDEAEDDDFEEDDDNDDRDADFQPQLSSDAGDDDDLPLAQRLRMKKKRSKRVKKEKEFLSGSGEDFDYDDGDEDGDDDGNEGDFKSKAKRKRIPADERHLHRIIDCHICHQKFKKAIRYEEHMKHHNDLLPFQCKVETCRKGFTTAGGLRLHIDHAHTELSEVHSCSVEGCGKTFPRVRLLTFHMKKVHNISKAAAPPRDYPCSECEKVFRCPMALKKHMYKHDGKELPFPCNICGKRFVINSALKDHLMRHAGIKNYVCPYCGVGKTTRQEWNTHILTHTQEKKFKCHICEHASHNKQSLANHIKIVHEKIKNYACQYCGKTFGKSHACKIHEMTHTGEKRCECKVCGKKFLYPKSLTKHLKTHEKRVLRAIETYRQRQVEMGETSGQGDQQQQQLDQVNIGLPNPTGSVTVTIAEPGVGEQLMSQNAADELLKVCAESVATIPKDPRRVQRVDISQLAGTAVNPISSVSVPSWSPQTTNFTKKEGKHICPGCGQGFNNIGNMKRHYKIIHEKVKDFACRFCPRRFAKAQTLRHHEWIHTGEKPFECKTCGTHFRQETALKRHQRTHENRPPVISSKFYAAREELEEQERSKREAKRKAEAKRKEIAEAAKEQLSTLHKLETIDKQLHSYDEYQEAAAERAAASAELQAQQNEENEVRRRADEERIKIQAAAYEQLQKLQEQQEIDKAQSSYDGYYAQKANADGTNYDALKIDHV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00571348;
- 90% Identity
- iTF_00612244;
- 80% Identity
- -