Dins014588.1
Basic Information
- Insect
- Drosophila insularis
- Gene Symbol
- -
- Assembly
- GCA_018903935.1
- Location
- JAEIFP010000003.1:956061-957446[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 0.0011 0.085 13.4 2.0 2 23 183 205 183 205 0.93 2 9 7.9e-06 0.00062 20.1 2.5 1 23 220 243 220 243 0.98 3 9 0.0017 0.14 12.7 0.7 1 23 264 287 264 287 0.94 4 9 2.3e-05 0.0018 18.6 3.2 3 23 292 312 291 312 0.98 5 9 0.00085 0.067 13.7 2.7 3 23 320 342 319 342 0.94 6 9 5.9e-07 4.7e-05 23.6 2.5 1 23 348 370 348 370 0.98 7 9 1.9e-05 0.0015 18.9 1.0 3 23 378 398 376 398 0.97 8 9 0.00077 0.06 13.9 3.5 1 23 404 426 404 426 0.93 9 9 0.00013 0.01 16.3 0.0 1 23 432 454 432 454 0.98
Sequence Information
- Coding Sequence
- ATGTTAAAGACTCTCAAGCCGGACACTTTCGCTGGCGTGGCCAATGCTAAGTGCGGCGAAATCTTTTTCCAGAGTTTGAACAGCTTTCGGATTGACTGCGTATTCTGTGATATGAAATGTTTTATATTTGACGATTTTCTCCTGCACATCCAGAATATTCATTTCGAGAATGGACTGCTTAAAACGGACGCAATGCAGAAGCTCCAGCAAAGGGAAACAAAGCAAGAGGTTACCGACTCACCTACCAGAGAAAGTACTCCTATTGTGGCTCAAATGAATCCATTTGTTTGGTATGAAAATGAGAAGGATGAAGATCATCACGCTGATGACAACGTTGCTGACGATCAGTCGTCAGATGAAGAGACCGAAGAAGAGACTAAGGTTAAGGCCATTATGAAATGGAATCAGGTTTGCCCAACGGATTCCTTGCGCCCCCTACGGGCACTAAAAGTCGACTACAAGGAAGAAGATGAGGAGTCGTACCAGGAGGAAGACGCGTCAGAAGCGGAAATAAAAGAGCAGTTGCCTCAGCAAGACAAGGCGAACTCATGTCCACATTGCGAGAAGAAATATCAAAGTAAAACAACCTTAGACCGCCACATCGCACAACAGCATAAAACGTCAAAGGATTCCCCCATTGAAATGACAAAATTTAAATTCAAATGTCAGTATTGTGATAAGATTTATAAGGGGAAATATTCTCTGCGTCAGCACGTTAAACGAGATCATGACTTGGACATAAAACAAGAAGCCACCAAAGGTCAAGCATCTGCCGCAACCTCTTCAACGTTTACCTGCCCCGAATGCCATAAGGAGCTACCTCGCCTCCGTCTCCTCGATGAGCACATGTTCCAGATGCATGGTGGCGCCCTTTGCCCTATATGCCAACGTCGATATAAGACCCGCCATGAACTCAAACGCCACCAACTGAATCATACAAACGAACGGAATGTGATTTGCTCATATGCCGGCTGCGAGAAACGTTTCTTTAGCCGCCGGCATATGCGAAATCATATGAAAGTCCATTCGGAGCAAAAGAATTTTGTGTGCGAGAACTGTGGCTACAGTTGCCGCAATAAGGAAACGCTGCGCGTCCACATGAGAAGCCACACGGGTGAACGTCCATTTGGCTGTCAAGTGTGCAACAAGAGATTTCCCTCCCATTCCGGACTTCGGGAGCATATGGCTATGCACTCAACTGAACGACCACATATATGCACAGTATGTGGAGCCACATTCTCACGACAGAAAGGACTCTATCATCATAAGTTCCTGCACTCGGCCACAAAGCAATTCGTTTGTAAGCTATGCGGAAATGCCTATGCCCAGGCTGCTGGTCTAGCCGGGCACATGCGTAAGCATCGGAACGATGAGCTCAATGGCTAA
- Protein Sequence
- MLKTLKPDTFAGVANAKCGEIFFQSLNSFRIDCVFCDMKCFIFDDFLLHIQNIHFENGLLKTDAMQKLQQRETKQEVTDSPTRESTPIVAQMNPFVWYENEKDEDHHADDNVADDQSSDEETEEETKVKAIMKWNQVCPTDSLRPLRALKVDYKEEDEESYQEEDASEAEIKEQLPQQDKANSCPHCEKKYQSKTTLDRHIAQQHKTSKDSPIEMTKFKFKCQYCDKIYKGKYSLRQHVKRDHDLDIKQEATKGQASAATSSTFTCPECHKELPRLRLLDEHMFQMHGGALCPICQRRYKTRHELKRHQLNHTNERNVICSYAGCEKRFFSRRHMRNHMKVHSEQKNFVCENCGYSCRNKETLRVHMRSHTGERPFGCQVCNKRFPSHSGLREHMAMHSTERPHICTVCGATFSRQKGLYHHKFLHSATKQFVCKLCGNAYAQAAGLAGHMRKHRNDELNG
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00523836;
- 90% Identity
- iTF_00523836;
- 80% Identity
- iTF_00523836;