Dins004988.1
Basic Information
- Insect
- Drosophila insularis
- Gene Symbol
- -
- Assembly
- GCA_018903935.1
- Location
- JAEIFP010002303.1:19021783-19024665[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 2.6 2e+02 2.8 1.2 2 23 122 144 121 144 0.93 2 13 0.0027 0.21 12.1 2.7 1 23 155 178 155 178 0.97 3 13 2.6e-07 2e-05 24.8 2.5 2 23 185 207 184 207 0.96 4 13 0.0089 0.7 10.5 9.1 2 23 383 404 383 404 0.97 5 13 9.7e-07 7.7e-05 23.0 2.8 1 23 410 433 410 433 0.96 6 13 0.00021 0.016 15.6 0.6 1 23 438 461 438 461 0.96 7 13 5e-05 0.004 17.6 5.5 1 23 478 500 478 500 0.96 8 13 0.00039 0.031 14.8 1.2 1 23 505 527 505 527 0.98 9 13 2.7e-05 0.0021 18.4 1.7 1 23 533 555 533 555 0.95 10 13 1.9e-05 0.0015 18.9 0.7 1 23 561 583 561 583 0.98 11 13 2.8e-07 2.2e-05 24.7 2.7 3 23 591 611 590 611 0.99 12 13 2e-08 1.6e-06 28.3 1.1 1 23 617 639 617 639 0.99 13 13 0.31 24 5.7 3.4 1 19 644 662 644 667 0.89
Sequence Information
- Coding Sequence
- ATGGCCACCACCACGAGCGGTAACGGTAAGGCCAATATCGAACGACTTTGCCGTATTTGCCTGCGTCAGGTGGGCGAGGAGCAGCAGTTTCACTTCATCTACGATGAAGCCCCCATGGAGCAGGGAGCCAATTTGGTTGAAATACTCAACGCCTGCACAAGCTATATGTGCGAACGCTCGGAAGATGCACCTGCCAAAATGCCACATCACATTTGCGAGGAATGCCTTAAGGCGGCCTGCCAAGCTTATCGCTTTAAGCGTGAGGCAGAGAAATCCTATTGCTCTCTTATGTCGTTGCTGGGCCTGGAGCCGGCAATCAAACATAATGAAGTGAGTACACAAACGGATCAGGTGGCGCTCTTGCCATGCGAGATGTGCCACGATAAGTTCCTGAATAGCCTGGAGCTGCGTTTGCATAGAAATCGTGAGCATAGCGGCCAAAAGGGATCACCTGCGGAAGAATTCAAATGCAAATTCTGTCCGCAGCAGTTCCAAAAGTTGCGCCAACTGCGCAGCCATTTGTCACGCATCCATGACCAAGTGGACAGGGTTCAATGTAATTTATGCGATCGAGCGTTTAGTCGGCGTGATCATTTGCAGCGACACATGAAGAACATGCACAAATCACAAAAATCCGAGGAGGAGCAACCAATTGACCCCGATGGACCAGATGAGCTGGAATCAGTTGAGGTCTTGCTCGATGATGTTGGCGTGGGGGAGGAGGAAAGCGAGTTGGGTAATGATCAGTGCAATACGAATCCCATTTCAAGTAATGAAGAGTCCGACGACGACAATGATGAGGCGAAAAAGTCACTTTGGCTTAACATTAAGCCAGAGCCATGTCTGGAAGCAGAGCCAGAGGCAGAACAAGTACATGTCAAAACGAATAAAAGACGTAGGAAGAAAGCAGAACAAGCAGAAGCCTTTGAGACCACAGAGGCAGAGGTCAAGGCTGAGCCATTGGCCCATGTTGAGTCAGTTTTGCACATTAAACAGGAAAGCCAAATGGGTCCTAGCGAGGAAGAGAATGCCTCTGTCCAAATACCAACAAAAGTGGAGATTGTTCGAGAATATCTACAAAAATCGAAGAAACCCAAACGCCGGCGTCGTCGCAATCGTGATGAAAGTGAACCCAATCCTGAAAATCGTTGCGATGTCTGTCAGCGAACCTTTTCCCGCCATTGTCATTTGCTGCGACACAAGCTCTCCCATCTGGAGAAGAAACCGCACAGTTGTCCCCATTGTCCCAAGGCTTTTGCCCGAAGCGATCACTTGAAGGCCCATGTCCAAAGTCTGCATAGTAGTAAGGAGCATAAATGCGAATTGTGCCAGGCTGCCTTTGCCCGTTCCGAAGCTTTGGAGCGCCACAAATTGAGTCGACACAACGGCGTCGGTATGCCAGAGGGCAGTGAGTTAAAACATCAGCTGGAGCACACCTGTGAATACTGTTCAAAGCGTTTCTCCAGTAAGACATATTTGCGAAAGCATACACTTCTTCACACCGATTTCCTTTATGCCTGTAAAAGCTGTGAAGAGACCTTTAAGGAGCGCCAACAATTACGTGAGCACGAGAAGACCCATACGGGTCAAAGGAATTTTCTCTGTTGCATTTGTGGTGATAGTTTTGCACGTAATGATTATCTAAGGGTTCACATGCGTCGGCATAATGGTGAAAAGCCATATAAGTGCCGTTATTGCGTCAAGGCTTTTCCTCGGGCCACCGATCTCAAGGTTCATGAGCGTTATCACACTGGCACCAAACCGAATTTGTGCAATACTTGCGGCAAGAGTTTCCATCGTGCCTATAATCTCACCATACACATGCGTACCCATACGGGTGAGCGACCCTACAAATGCGATCAGTGTCCCAAGAGTTTCACCCAGAGTAACGATCTCAAGGCCCATATACGTCGGCATACGGGCGAGCGTTACAAGTGTCCGCACTGTGACGCCTATTTCCTGCAGTTATATAATATGCGTAATCACTGCCTTAGTGCCCATAATAAGCATATTGAGACAAAAACGGGTCGTCTACAACGCACCGGACTTCTGGACGAAGGCAATCAATCACATTTCACTACGGTAGTAATGCCGCCAGGTCGTTATCAAGAAAACCATCATCAACAAATGAATCAGACAAATCAATCCCAAACGCATTTGACAGCCACTTCGACTGCGGTGCTACATTCACCGACTTCGGGTAGTGGTGGTGGTGTATATAATTCCACAACCACTGCCACATCCTTGACCACCACGGGAACAACTGTTCCGGCAGCTGCGGGCGCTGTTGCCAATTTGGATGGGGCTAGTTTTCCCTCAGCAACAGCCCCAGCCTTTGGGGCATTTAATTTTCCACCTGTTGTAATGGCTCATCTTATGTATAATCATGGAGGAGGCGGCGGCGGCGGAGGCAGCAGTAGCCAGCATAGTCAACAGAGTAATGCCAGTGGCAGTGAATCGGCTGGTAAATAA
- Protein Sequence
- MATTTSGNGKANIERLCRICLRQVGEEQQFHFIYDEAPMEQGANLVEILNACTSYMCERSEDAPAKMPHHICEECLKAACQAYRFKREAEKSYCSLMSLLGLEPAIKHNEVSTQTDQVALLPCEMCHDKFLNSLELRLHRNREHSGQKGSPAEEFKCKFCPQQFQKLRQLRSHLSRIHDQVDRVQCNLCDRAFSRRDHLQRHMKNMHKSQKSEEEQPIDPDGPDELESVEVLLDDVGVGEEESELGNDQCNTNPISSNEESDDDNDEAKKSLWLNIKPEPCLEAEPEAEQVHVKTNKRRRKKAEQAEAFETTEAEVKAEPLAHVESVLHIKQESQMGPSEEENASVQIPTKVEIVREYLQKSKKPKRRRRRNRDESEPNPENRCDVCQRTFSRHCHLLRHKLSHLEKKPHSCPHCPKAFARSDHLKAHVQSLHSSKEHKCELCQAAFARSEALERHKLSRHNGVGMPEGSELKHQLEHTCEYCSKRFSSKTYLRKHTLLHTDFLYACKSCEETFKERQQLREHEKTHTGQRNFLCCICGDSFARNDYLRVHMRRHNGEKPYKCRYCVKAFPRATDLKVHERYHTGTKPNLCNTCGKSFHRAYNLTIHMRTHTGERPYKCDQCPKSFTQSNDLKAHIRRHTGERYKCPHCDAYFLQLYNMRNHCLSAHNKHIETKTGRLQRTGLLDEGNQSHFTTVVMPPGRYQENHHQQMNQTNQSQTHLTATSTAVLHSPTSGSGGGVYNSTTTATSLTTTGTTVPAAAGAVANLDGASFPSATAPAFGAFNFPPVVMAHLMYNHGGGGGGGGSSSQHSQQSNASGSESAGK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00618572;
- 90% Identity
- iTF_00618572; iTF_00503412;
- 80% Identity
- -