Basic Information

Insect: Drosophila insularis
Gene Symbol: -
Assembly: GCA_018903935.1
Location: JAEIFP010002295.1:13481976-13486603[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 25 0.001 0.08 13.5 1.1 1 23 215 237 215 237 0.97

2 25 0.0024 0.19 12.3 2.1 1 23 243 265 243 265 0.98

3 25 0.001 0.083 13.4 0.2 2 23 297 318 296 318 0.95

4 25 0.012 0.93 10.1 2.1 1 22 392 413 392 415 0.89

5 25 6.8 5.3e+02 1.4 0.7 2 21 425 444 424 445 0.90

6 25 0.57 45 4.8 0.3 3 23 486 506 485 506 0.96

7 25 0.018 1.4 9.5 3.4 1 23 586 609 586 609 0.96

8 25 0.28 22 5.8 1.5 1 22 618 639 618 639 0.92

9 25 0.33 26 5.6 3.9 1 23 648 671 648 671 0.97

10 25 4.2e-05 0.0033 17.8 0.4 2 23 694 715 693 715 0.97

11 25 2.4e-05 0.0019 18.6 5.7 1 23 723 745 723 745 0.98

12 25 0.0068 0.54 10.9 2.3 1 23 892 914 892 915 0.95

13 25 0.095 7.5 7.3 0.9 2 21 924 943 924 944 0.92

14 25 0.67 52 4.6 5.5 1 23 953 976 953 976 0.94

15 25 8.6e-06 0.00068 20.0 4.3 2 23 991 1012 990 1012 0.97

16 25 0.00012 0.0097 16.3 0.9 1 23 1018 1040 1018 1040 0.98

17 25 0.014 1.1 9.9 0.3 2 21 1067 1086 1066 1087 0.94

18 25 0.0078 0.61 10.7 4.8 1 23 1133 1156 1133 1156 0.96

19 25 3 2.4e+02 2.5 0.5 1 23 1193 1216 1193 1216 0.92

20 25 6.4e-05 0.0051 17.2 1.8 1 23 1252 1275 1252 1275 0.98

21 25 5.1e-06 0.0004 20.7 0.2 2 23 1314 1335 1313 1335 0.95

22 25 0.00021 0.016 15.6 3.1 1 23 1341 1363 1341 1363 0.99

23 25 2e-06 0.00016 22.0 2.0 1 23 1369 1391 1369 1391 0.97

24 25 1.8e-07 1.4e-05 25.3 2.4 1 23 1397 1419 1397 1419 0.99

25 25 0.00047 0.037 14.5 0.2 1 22 1425 1446 1425 1449 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	25	0.001	0.08	13.5	1.1	1	23	215	237	215	237	0.97
2	25	0.0024	0.19	12.3	2.1	1	23	243	265	243	265	0.98
3	25	0.001	0.083	13.4	0.2	2	23	297	318	296	318	0.95
4	25	0.012	0.93	10.1	2.1	1	22	392	413	392	415	0.89
5	25	6.8	5.3e+02	1.4	0.7	2	21	425	444	424	445	0.90
6	25	0.57	45	4.8	0.3	3	23	486	506	485	506	0.96
7	25	0.018	1.4	9.5	3.4	1	23	586	609	586	609	0.96
8	25	0.28	22	5.8	1.5	1	22	618	639	618	639	0.92
9	25	0.33	26	5.6	3.9	1	23	648	671	648	671	0.97
10	25	4.2e-05	0.0033	17.8	0.4	2	23	694	715	693	715	0.97
11	25	2.4e-05	0.0019	18.6	5.7	1	23	723	745	723	745	0.98
12	25	0.0068	0.54	10.9	2.3	1	23	892	914	892	915	0.95
13	25	0.095	7.5	7.3	0.9	2	21	924	943	924	944	0.92
14	25	0.67	52	4.6	5.5	1	23	953	976	953	976	0.94
15	25	8.6e-06	0.00068	20.0	4.3	2	23	991	1012	990	1012	0.97
16	25	0.00012	0.0097	16.3	0.9	1	23	1018	1040	1018	1040	0.98
17	25	0.014	1.1	9.9	0.3	2	21	1067	1086	1066	1087	0.94
18	25	0.0078	0.61	10.7	4.8	1	23	1133	1156	1133	1156	0.96
19	25	3	2.4e+02	2.5	0.5	1	23	1193	1216	1193	1216	0.92
20	25	6.4e-05	0.0051	17.2	1.8	1	23	1252	1275	1252	1275	0.98
21	25	5.1e-06	0.0004	20.7	0.2	2	23	1314	1335	1313	1335	0.95
22	25	0.00021	0.016	15.6	3.1	1	23	1341	1363	1341	1363	0.99
23	25	2e-06	0.00016	22.0	2.0	1	23	1369	1391	1369	1391	0.97
24	25	1.8e-07	1.4e-05	25.3	2.4	1	23	1397	1419	1397	1419	0.99
25	25	0.00047	0.037	14.5	0.2	1	22	1425	1446	1425	1449	0.91

Sequence Information

Coding Sequence: ATGTTGCCCTCGGATATTTGCCGTACCTGTGCCACACAGAATAACAATTTATTGCCGCTTGCCTCCTGCTCGGAGAAGCTACAGGAATTAACACAAATTCCGCTATTGGAGCTCATCGGGGATGAAAATTTACCCCAACATTTGTGTGCGGATTGCTTGGGTAAATTGGAGAATGCTTATGCCTTTGTGGAGCAAGCGCGGAAGGTGAACAGGGATCTGCTCATGAAGTTGAGGCAGTGCCTTCTCGAGGAGACTCCCATTGATATACCCATACCCAATGCAATGCAACATCAAATAAAAATGGAGATGGACGACGAGGATGGTGACCAGCAAGAGTTAGACGAAGAAGAGACTGCAGCCACAAGATTGGAACTTAAATGGCATGCAGACAGTGAGGCCGAAAGTGAAGCAGAGGAGGAGGAAGCCGCTGATGGCAATGAAGAAGAATACAAGCCATATCAGCCTAGGCGTAGCCTACGTAAAATTAAGCAGCAATCCGATAGCGAAGAGGAATATCAAGATCGCGATGAGGAGAAAATTAATTTAAACCTTGAGAAAAATGATCCGGAGCCGCCTCCTAAGCGTCGTCGGGGGCGCCCACCGCGTCTGGCCAAAACTCTAGCTCTCAATTCCGAGGGTCGTCACGTTTGTGCTGAGTGTGGAAAAACCTTCTCCTGGTATAGGGATATGCAGCGCCATGCTCGCAGTCATTTCGAAGAAGCCGCCTTTAACTGTTCGCAATGCGGCAAGGGATTCCTACGCAAGGATAAATATATGTCTCACCTTAAATCCCATGAGAAACGCCAGGCAAAACGAGAAAATGTTGAATTATCTAAAGAATGGATATTCGCCGAGCGGTTATATACTTCGGAGCAATTAAAGCTTATCGAATGCAAATTGTGTGGTGTGCAGTTCGAACGATTGAAAGACTTAAGATCCCATTTGGAGCTTCATTCGTCTAAAGAAACTCTTGGTCAACTGCAATTGGATCAAGAAGTGGTGAAGGAGCACTTTGCCGATGAAAATATTGATCTAGAGAAGGTCAAGGATCTAATAACAAAAGATATAAGTGAAGGGCAGTTAGAAAAATTCTGTGCTGTGGTCAATTCGAATGGTTATGAATTAAGTTTAAGTGATTCCGATGAAGATTCGCCTCCAGAAGTCGAACCCAAGTACCATTGTGTCTCATGTAATGTGCCCTTTAAGCGCAAACATTTGCTCATTCGTCACACAGTGGAAGAGCATTCCAAAGGGCATAATCAGCCACAATTACGTTGTAATCTCTGCCAGATCGGTTTCGTTTGCCTAAATTTGTATGAGCAACATCAACGTTCGCAGTGCTATGGAAAATTTAAGCGATATGGCTGCCGAAAATGTCCAGGAAAGTTTATGTGGTTGGAGAATTTGGAAAAACATGAATGTGTCCAAAGCAGGGAGGAGGACAAACAAATTCTATGCTGCCTTTGCGATGCTCAATTGCCCAGTTTAGTCCAGTTGAGAGCACACTTGCTCAGTCATCGAGATGGCTTGACGGGAATTGATCCTCTATATCAGGCAACATTTTTCCGTTGCTATTATCCAAAAGGTTTGGCCTGCAGCCAGTCCGAACTTAGCTCCCGTATAGTTGGCGACTTCGATGCTCAAGATTATGGTCGGTATTATAATGCTAGCCTTAGTTCGGGACAGGAATTAGATTTCTACGACTCCGATTCGGATGAAAGTGATGCACCTGGAGAATCTCAAGAAAAGCCTCTGCACACATGTTCTTTGTGCGGCGAGACAATGAAACGTTTAACAAATCTTATCGAACATCAACAGAATTGTCATCAACACGAAATAGAATCGTTTACTTATTCTTGCAAGGATTGTTCAGAGAGATTCGTGTGCGATGCTCTTCTGCAGCAGCATCGACGTCGTTCATGTGGCAAAATGCATGCTAAATTCCATTGTCAGCTATGTCAAATGCATTTCGTTTGGCAAACTAACTATGAGCAACATTTGCGCGTAAATCATCCATCCGAAAAGGATATGGATCAGAATATTAAACGGAAACCTGCAGCTGCCCCTTCTGCCAGACTGCAGTGTAATGAATGTGATAAGGTCTTTATTTGGCCGAAGGACCTTAATCGCCACAAGCGCATGCATCAGCCCAGAACAGCATCTCAATTTGAATGCACTCACTGTGAACGTAAATTTCATCGTAAAGATGGCCTCAAGTCCCACATGCGAGTGCACAGCGAAGAGATGCAACAGATGGAGAAGACTGATAATGATGAGCACGATGAGAAACCACAAGCAAGCCAGATATTAAGCGAATTAAGTCGGCCACATGGCTGCAAGCAAATTCAATGCATGATCTGTCATTCGCAACACTCAAAGATAGCCGATCTGCGATGTCATCTAATGTCCCATCAGTTTGTTATCAGCTTGCCGCCCGAGAGAGAAAAAGATATTGTTGGAGTTTCCAAATCATTATATCCCGAATTGAGTGTGGCCCTGACCCGAGATAATTTAATATCACGCATTATGAACGATATTGGTAAGGGTGTAGAACTAGAGAGATTCATATCTATAACGAATGAATCGGGCTTTGAACTTAGTTTGGATAGCAGCGAAACGGACTCAGACACCGATGAAGAGGATGCTAAGTCGGATAGGCAAAAAATTAATCGCTATATTTGCACCATTTGTCAAGTGGAAGTAAAGAGAAAGCATCAATTATATGCCCATCAATTGGATCACCATCCTTGTGCAGAGGCAGCCACAAATGTGTGCTCTCATTGTCAAGCGAGATTTGTGAGTGAGCAACTTCTCGACCATCATTTGAAGTCTCAGTGCCGAAATAACCAGAAGAGGCATCAATGTCGAAAATGCACATGGCGCTTCCGTTGGCGTGAGAATCTCAAACTCCATAACAATGTATGCCATCAAGCAGATGATTCTTTATTAGGCCCAGATGGTGGAGAATTGCGTTGCAAGGAATGTCATCGAACCTTTAAAATGCAAAAGGACTTAACTCGTCACATGCTAATGCACTCGGATACGAGTATTTATCGTTGTCGTTGGTGTGCCCGTCGTTTCTATCGCCAGGCCAATCTTCTACAGCATATTGAACGACATGGCATCAGTGCCGATCAATTGCCTTATGCCGAATCTCTTCTTAATTCATATAATCATCCGAATGGTCAGAAAATCATTCAATGTAAAGTGTGTAACATAAACTTTAACTCAATCATTGCGCTGCGGCATCACTTGAAGTCCGCTCCCAATGAGTCGCACCATCAACTTTCGTCCATGCAAAACTATTCCATTACCAATCAATTGGGCTATGAACTGAATTTGGACGACTCGGAAACAGATGACGAGGACATCAAGTCTGGAGGCAGTAATGAAATCTATACCTGCAGCATGTGCCACTTGCGTTGTGCAAGGAAATATGAACTCTATCAACATCAACAGGCCATGCATAGGCTAGAACGTATTCCCGATGGCTGCGATCAGTGCATTTTCAAGAGCGTATCTTCTGATATCATCGAGCATCATAAGCGTAATCAATGCGATAATCAGGAGAAAACCTTTAAATGTATTAAATGTGGCTTCAAATTCATGTGGGAATCGAATATGTTAATCCACATGGAACTGCAACATCAGAAAAACGAAGACGAAGATCAAACCCAGGAACAACAAATTGTGGAGCCAACAACGGAGTCAGTTAATAATTCATCGTCAAGTTCCAAACAAATGCAACAGATCTTCCAATGTGCTCTCTGTCCCAGAAAATACAATCGCAAAGATCGCCTCACCGCGCATATGAAAAAGTTTCACAATCCAAATGGGCCAAGCACCACATCAGGAGCCAGCCAGTCATCTACTGCCTCCAAGAAATCTTCAGCGGCATCTTCATCTTTAGCTTCTGCCACCAAGCAACCAAAACTATTTCTCTGTGCCTTCTGTGGCAAGGCAGTGAGTTCTTCATCCAATCTTATAATTCACATGCGACGACACACTGGGGAGAAACCCTTCAAATGCGATTTCTGTGACATGGCTTTTCCACGTTCCTCGGATCTGCAGTGTCATCGGCGAACACATACGGGCGAGCGTCCTCATGTGTGTACAGTGTGTCAAAAAGGTTTCGCCAGATCCTATAAATTACAGCAGCATATGCGCATCCACAATGGGGAGCGACCCTACAAGTGCACCTATTGCGAGAAGAGTTTCACGCAATCCAACGATTTGACACTACATATACGACGCCACACCGGCGAGCGGCCCTATCAATGTGGCATCTGTGGTGAGAGATTCATTCAGGGTACTGCTCTAAAGAATCATCGTCAGCAGCAGGGGCATCATGAGCCAGGCGCTCCGGGTGGCATGCCTGGAGATGCGCCCATAAGGCGCACAGTTCTTCAGCAATTTTCGGGCGAATGA
Protein Sequence: MLPSDICRTCATQNNNLLPLASCSEKLQELTQIPLLELIGDENLPQHLCADCLGKLENAYAFVEQARKVNRDLLMKLRQCLLEETPIDIPIPNAMQHQIKMEMDDEDGDQQELDEEETAATRLELKWHADSEAESEAEEEEAADGNEEEYKPYQPRRSLRKIKQQSDSEEEYQDRDEEKINLNLEKNDPEPPPKRRRGRPPRLAKTLALNSEGRHVCAECGKTFSWYRDMQRHARSHFEEAAFNCSQCGKGFLRKDKYMSHLKSHEKRQAKRENVELSKEWIFAERLYTSEQLKLIECKLCGVQFERLKDLRSHLELHSSKETLGQLQLDQEVVKEHFADENIDLEKVKDLITKDISEGQLEKFCAVVNSNGYELSLSDSDEDSPPEVEPKYHCVSCNVPFKRKHLLIRHTVEEHSKGHNQPQLRCNLCQIGFVCLNLYEQHQRSQCYGKFKRYGCRKCPGKFMWLENLEKHECVQSREEDKQILCCLCDAQLPSLVQLRAHLLSHRDGLTGIDPLYQATFFRCYYPKGLACSQSELSSRIVGDFDAQDYGRYYNASLSSGQELDFYDSDSDESDAPGESQEKPLHTCSLCGETMKRLTNLIEHQQNCHQHEIESFTYSCKDCSERFVCDALLQQHRRRSCGKMHAKFHCQLCQMHFVWQTNYEQHLRVNHPSEKDMDQNIKRKPAAAPSARLQCNECDKVFIWPKDLNRHKRMHQPRTASQFECTHCERKFHRKDGLKSHMRVHSEEMQQMEKTDNDEHDEKPQASQILSELSRPHGCKQIQCMICHSQHSKIADLRCHLMSHQFVISLPPEREKDIVGVSKSLYPELSVALTRDNLISRIMNDIGKGVELERFISITNESGFELSLDSSETDSDTDEEDAKSDRQKINRYICTICQVEVKRKHQLYAHQLDHHPCAEAATNVCSHCQARFVSEQLLDHHLKSQCRNNQKRHQCRKCTWRFRWRENLKLHNNVCHQADDSLLGPDGGELRCKECHRTFKMQKDLTRHMLMHSDTSIYRCRWCARRFYRQANLLQHIERHGISADQLPYAESLLNSYNHPNGQKIIQCKVCNINFNSIIALRHHLKSAPNESHHQLSSMQNYSITNQLGYELNLDDSETDDEDIKSGGSNEIYTCSMCHLRCARKYELYQHQQAMHRLERIPDGCDQCIFKSVSSDIIEHHKRNQCDNQEKTFKCIKCGFKFMWESNMLIHMELQHQKNEDEDQTQEQQIVEPTTESVNNSSSSSKQMQQIFQCALCPRKYNRKDRLTAHMKKFHNPNGPSTTSGASQSSTASKKSSAASSSLASATKQPKLFLCAFCGKAVSSSSNLIIHMRRHTGEKPFKCDFCDMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHNGERPYKCTYCEKSFTQSNDLTLHIRRHTGERPYQCGICGERFIQGTALKNHRQQQGHHEPGAPGGMPGDAPIRRTVLQQFSGE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00612227;
90% Identity: iTF_00612227;
80% Identity: -