Dins008876.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila insularis
Gene Symbol
kipf
Assembly
GCA_018903935.1
Location
JAEIFP010002295.1:17385084-17390064[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 1.7e-05 0.0013 19.1 2.3 1 23 159 182 159 182 0.97
2 16 1.2e-06 9.7e-05 22.6 1.7 1 23 188 210 188 210 0.98
3 16 7.8e-07 6.1e-05 23.3 0.7 1 23 216 238 216 238 0.99
4 16 8.5e-07 6.7e-05 23.1 1.3 1 23 244 266 244 266 0.99
5 16 4e-06 0.00032 21.0 1.3 1 23 272 294 272 294 0.99
6 16 0.78 61 4.4 2.8 1 23 306 329 306 329 0.95
7 16 1.2e-06 9.6e-05 22.7 1.6 1 23 396 418 396 418 0.98
8 16 0.022 1.8 9.2 0.8 1 23 424 447 424 447 0.96
9 16 0.039 3.1 8.5 3.9 1 23 543 566 543 566 0.97
10 16 1.7 1.3e+02 3.3 3.7 1 23 625 647 625 647 0.98
11 16 1.1e-05 0.00083 19.7 2.0 2 23 652 673 651 673 0.97
12 16 1.7e-06 0.00014 22.2 0.6 1 23 678 700 678 700 0.97
13 16 0.0021 0.17 12.5 1.2 1 23 730 753 730 753 0.96
14 16 1.4e-05 0.0011 19.4 0.6 2 23 841 862 841 862 0.97
15 16 4.8e-07 3.8e-05 23.9 1.3 1 23 868 890 868 890 0.98
16 16 0.0063 0.5 11.0 2.3 1 23 895 918 895 918 0.91

Sequence Information

Coding Sequence
ATGGATCTAGATCCAAGCTTGGAGAATGTTTGTCGTGTTTGTAGGGATGGGTCTGTCACATTGGTGGACATATTCAATGGAGTGGACGCCGATGAGGATCATGAGAAGAATTTAGCTTACGTCCTGAGCCAGTGTACTAACTGTCAGGTTAATCGCGATGACTTATTACCCAAACAAATATGTTTGTCTTGTGTCCTGGCTGCACAAAATGCATTCCGTTTTAAGAAGACATGCGAACAGAGCCATCAGCACTTTTGCGAAATCCTTCAGATGAGATGGCATAGAAGCCAAGCAGAGGAGTTGGTTTTCAATGATGATGATGTACACATGGCAGGTGGTCTCCATGTCATTGATGCGAGCTGCATTAAACTGGAGCCGATGTCAGAGCTCCAGGAATACGCCATGCAAGAAAATTTACAAATGGAAAGTCCCTCCACTGAGGAACAGGAACACACAACTGATGAGGTGTTCTCACATGTGTGTCAGTACTGCACCAAAGGATTTCGTGGCTCGTATGAGCTGAACAATCACATTCGTAGTCGCCATACGGGTGAGCGTCCATTCGAATGCCCTCATTGCCCAAAGAAGTTTGCTACAATAAACTATCTAAGAAAACACATTCGGCTCCATACGGGAGAGCGTCCTTATAAATGCCCACATTGCCCTAAGGCCTACACCCTGTGGAACAGTCTTAAGGCTCATATTAGTACGCATGGTGGGGAACGTCCATATGAATGCCCCCACTGTCCCAAGAAGTTTGCTATTACGGACTATCTAAGAAAACATATGCGGATCCACACAGGAGAGCGTCCTTTTAAGTGTCCTCATTGCCCTAAAGCCTACACCCTGTCGAGCAGTCTAAGTGGTCATATTCGTAAGCATGATGGTAGCCACCGCAACTTAATTACAAAACTATTTCGATGCAATCAGTGTCTAGCGTCCTACCGGGAGTACTTTAAGCTGCGCATGCACAAGCAATTGAAGCATCGCGTCAATAATACCATAGACAACGCTAAAGCAATGGAAAAACTAAAACAGTCAAGTAATTGTTCCGGAACTAATAACAACTCCAACAGTAGTTTGCCTAATTCGATCCTTGAGGAGAGAAATGCGGAAATTAAGAAAGAACCTGACGAAGAGGATACTCAACCAACAAAGAATCAATCCCAACAGCAAGAGACTAATTATTCCTGTGAGATATGTGACAAGATATTTAAATATAGATACTCTTATAACAATCATATGCGTGCTCATGTGAGACGACGGCAATTTGAATGCTCACAATGCCTACGAAGATTTGTAAGCAAACAGACTCGAAATCTGCACATCAGCGTGGTTCATTCAGAGGACTGTCAGGATTTATCAATGGAACGAACTAACGATTACCAGAGGTCGATAAAATCTGAAGTTCCAGATAGGAATTCACCTCATGAATCTCTTCTAGTAGAACAAATCCTACCAGATCGAGGCTGTGAAGGTCTTGAAGAGCCAAATACTTCTCACATTCTTTATGGTCATAAACAATCGAGGAATTTGACTAGACCAGCAAAACCTGCGAAGCCACGGAAGCCGAAGAAAAAATCAAAGGCCAAAAAATCTATGTACAAAGCCAAAGGAATGATAAGTTATCGCTGCAGATGGTGTCCAATAGCTTTTCGAGAACATCATAAAATGATGTCGCATATGCAGCAGAAACACAAAAAACGACTAATGGAGAGCTCGATCCTTGAAAAAGCCAACGAGCCAGAGACAAACCAAAACGAGCCAGAGATTATCACCCAAACAAATCCTACCGAAAAGGAGATAAAAGAAGAAATTGACCCAGCGCCATCTGTGAAAAAAGACTCAATACCTAAAAAAATTACGAAGGCTCACAAGTGTAGTGCCTGTGGAGACATGTTTACGGCAAGATTCAAATATGTTCAACATATTCATACACACCAGCCGCCTTTAAAGTGTAAAGATTGTCCAAAACAATTCAATACATATACTCAGCTCCGAGTTCATTCGAGGACACACAAAGGCGTGCGTTTTCAATGTGCTTACTGTCCAAATTCCTATTCGCGAAAAGATAATTTGACTAAACATATGGGTATACACAAAAAAAGAGGGGATGTTATTCAGTCAGCAGAAAATACCGATACGGATCCAATTGATGATGAGATATTTGCACAAACGAAGACCGAATTTAGCTGTGAATTGTGCTTGAAATCATTTTACCCTGAATATAACCTAAGGCTTCATAAGCTTATGAAACACGGCATTAACGACGAGGAGGAGCGGGAGGACGAGTTAATATTAGACCACCATCAGATTAATTTCGGCTTGGAACATGAAACAAATTCTACACTGCGAAATAGACCTAGAGCTGGGGCATACGAAGAACTCGAATTCGAGGATAGCGATGTGGATAAGCTTAACATTAACAGTAACAAGGAAATCTCGAATCCAAAACCAATATTAATGCCACAGACACACATTCAATTGCCAAATATCGACAAAAATAAGACAAAGGGTAATGTATGCCCGTACTGTTTGAAGCGTTACGTACGGAAAGAAAGTCTAACTATTCATTTGAGACGTCATACTGGCGAAAGGCCGTACAAATGTCCCTATTGCGAGTTAAGCTTCAGTTCAAATGACTCTTACAAACGACACCTCCGAGGACATACGGGAGATCTCTTCCGTTGTGATAAATGCCCAAAGGTTTATAAGGGTCGCTCTGATTTGCGATTTCATAAAAATCAGAAACATAAGGTTCCCAAAGAGGAGCCAATAGTATTAACCAAACATTTAATTGTACGTTTAAAACGAATTAAACTACCAGTCAGTGTTAAGATAGAGCCGTTTGACTAA
Protein Sequence
MDLDPSLENVCRVCRDGSVTLVDIFNGVDADEDHEKNLAYVLSQCTNCQVNRDDLLPKQICLSCVLAAQNAFRFKKTCEQSHQHFCEILQMRWHRSQAEELVFNDDDVHMAGGLHVIDASCIKLEPMSELQEYAMQENLQMESPSTEEQEHTTDEVFSHVCQYCTKGFRGSYELNNHIRSRHTGERPFECPHCPKKFATINYLRKHIRLHTGERPYKCPHCPKAYTLWNSLKAHISTHGGERPYECPHCPKKFAITDYLRKHMRIHTGERPFKCPHCPKAYTLSSSLSGHIRKHDGSHRNLITKLFRCNQCLASYREYFKLRMHKQLKHRVNNTIDNAKAMEKLKQSSNCSGTNNNSNSSLPNSILEERNAEIKKEPDEEDTQPTKNQSQQQETNYSCEICDKIFKYRYSYNNHMRAHVRRRQFECSQCLRRFVSKQTRNLHISVVHSEDCQDLSMERTNDYQRSIKSEVPDRNSPHESLLVEQILPDRGCEGLEEPNTSHILYGHKQSRNLTRPAKPAKPRKPKKKSKAKKSMYKAKGMISYRCRWCPIAFREHHKMMSHMQQKHKKRLMESSILEKANEPETNQNEPEIITQTNPTEKEIKEEIDPAPSVKKDSIPKKITKAHKCSACGDMFTARFKYVQHIHTHQPPLKCKDCPKQFNTYTQLRVHSRTHKGVRFQCAYCPNSYSRKDNLTKHMGIHKKRGDVIQSAENTDTDPIDDEIFAQTKTEFSCELCLKSFYPEYNLRLHKLMKHGINDEEEREDELILDHHQINFGLEHETNSTLRNRPRAGAYEELEFEDSDVDKLNINSNKEISNPKPILMPQTHIQLPNIDKNKTKGNVCPYCLKRYVRKESLTIHLRRHTGERPYKCPYCELSFSSNDSYKRHLRGHTGDLFRCDKCPKVYKGRSDLRFHKNQKHKVPKEEPIVLTKHLIVRLKRIKLPVSVKIEPFD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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