Dinn012539.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila innubila
Gene Symbol
-
Assembly
GCA_004354385.1
Location
NW:21371236-21385408[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 0.00074 0.042 13.9 2.0 1 23 761 783 761 783 0.98
2 8 0.0002 0.011 15.7 1.3 1 23 815 837 815 837 0.97
3 8 1.1 62 3.9 0.4 1 19 844 861 844 867 0.85
4 8 0.0029 0.16 12.0 0.0 3 23 874 895 873 895 0.96
5 8 0.00024 0.014 15.4 3.5 1 23 901 923 901 923 0.97
6 8 0.034 1.9 8.7 0.2 1 23 930 953 930 953 0.95
7 8 0.00031 0.017 15.1 2.2 2 20 960 978 959 981 0.91
8 8 0.23 13 6.1 10.7 1 23 987 1010 987 1010 0.96

Sequence Information

Coding Sequence
atggaTAACAAAACTACACAGTTGGATTTTAAATTACTgGTGGATCAGTCAGTGAATCTACTGGACAGTCTGAATGCGGCGTCGCGGTGCgatgcaattaaatttctgCTGCAAACGCTTAAGTGCAAATATCCAGAGGCCTGCGACCGAGTCGTCAGGAATCTGTTCAGTCACAAGCCCAATGATAATGGAGCCGACACGGAGTCGGAGTCAGAGTCGAAGCAGCTAGCGAAGAGCAagcagttgcaactgctgcttgCCACCAAAAAGGAGAAGACCGAACCGGGCACGATCATCGATGGATCGGTATCGGtatcgaaaataaaatgtgagaGCGATAATGAAGCATCATCCGCGATcgatttaaatcaaaactttGAGAAGATTCTCTGCAAAGAGGAGTTTATGTGCCTCGACGAGGAGGATGACTTCCTCAATGATGaagatgccgatgccgataaCGATGGCGATGCGGATGTCGATGTTGATGCCGATACCGAGAACTCGTCTTCCATGAGCAAACGCCTGCACTTTCATCGCTCCGCCAGTGGGAGCAACAATGTGGATGCGATTACAGCTGCAGGTCTACTCACCAGCGATCCCCTCGATCTGATTCActcggcggcagcagcaagtGGGTTGGTGAAACGCAAATATGTGGCAACATTTGATGAGGAAGAGGAcgaggaggatgaggaggacGATGAGACAGATGACGTGGAAAAtgagagcaacagcaatagctgTGAGGAGCTCTTACTGCGTCGGCAACAAAAGCTAATCCGCTCCAGGGCGTTGGTTAAAAGAAAACGAACCAACAACATCATAAGCAACATGGATGCTGTGGCGCCTGTAGCACGCTCCCGGCTGGGGGAGGGTTACGTGTTCCACGAGGATACCCAGTACACGTTGCGATATCATCACAGCAGCGGAGAGTTCAGTGAACGGGCCTTTAAGGCGCAGTTTCGGGTGCTACTCCGATTGGCGCTGAGTCAGCATCACAAGCCCTTCCTTAAGCAGTTCTATGACAACTTTGTGGTCACCGGACGTCTTCTGGGCACCACGCCCGCGACACGTGTGCTGAAGGAGCTGCGGGAGCAACGGTTAGACGAGTGGCGCCGGCAACGGGAACGAAGGCAGCAGGCCAAGGAAGCAgcggcggctgctgttgcagcattGCGGGAACTGGAGGAGAAGCGTAAGCTAAAGCAGAGTCAGCCACTGGTTCAACAATTGGAAGTGCCGCTGCAGCTGGATAATCAAGAGCCACGTCAGCTGAGATCCATATCGTTTGGTGACTCTGAGCTCGAGTCGGAGACGGAGTCACAGCTGTCATCGGCGGCACAGGAGATTATGAAGTTTGAGGAGTTTATTGACGAAGGTGTAGGCGCAGGTCGTCTCATTGATGGGCTCGAAATGGAGCCGGAAATAGATGAGATGCTGGCCGGTGCCGGCAGCGGATTAGGCAGCGTAACTGGCACCGGCAGCgggaacagcaacagcaacagcagcgccgTCCATGACAACGGAATCGCGTCGCTTCTCATGGACACCAATCATGGGACGCAGCTTCATTCCCATCATCTcagcagtagcagcaccAGTGTAGGTGGAAATCTTGTGATCAACGGCCTTACGTCAAGCaatatcaacaataacaacaattgtaacaagagcaacaatgTGGTCAATCAGCAACTGGGGCAGGAGCATCCTTCCAAGCAGTCACAGCAGCTGCAGTCACAGTCACCGCATTTGTCCATGCCCGTGAGATCTGCATATGGACACGAAGGTGTTGCCATGTCGGCCACAGCGCAGTTAATGTCAGGAACAGAGATTCAGCTCCAGAATGATAATCCCAATCATTACAACTCAAGCAATAATCCACTCTCGATGATGGGTGGCATGATGcaaatgcagcaacagcagcagcaacaacaacaacagtttccACAACATCAACATGCACAAATGCTGAACAATCATCAGCCACATCTGCATCCACATCCTCATCCACACCAGCAATCTCAGGCAGCTCATCTGTCCTCGTCTGTCATCGGTTCTAATGCCTGCGGACAATTGAACTCCTCGCTGGAGCTGGACGACAATGAGTTATCGGGCgacgaggatgatgatgaccTGGACAATGAACTTGACGAGATGGACGCTGCCAAGCAGCAGCTAATCGAtggaggcagcagcagcagcacctcCCTGCAGGCGCCGCCTTCTCAGCTTGGTGGCGGACACACGCCCGGGAGCAAAAAGGATAAACCTAGCTACAATTGCCTGTTGTGCCCCAAGTCATATAGGAAACGTAAATCTCTGCTGGATCACTACAAGATGCATCCCGGCTACTGCCACGACTGTGGGCAGCCCAATGGCAACACGCTGGAGGAAATCATTCAGCACAATCGCACGATGCATGTGAAAGAGTTTCCCTTTGTGTGCGAGACCTGCGGCGAGTCCTATTCACGTCGACAGCAGTTCCACGCCCATGTGGAGTCGCACAAGAAGGAATTCAAAATGTTTCCTTGCGGAGAGTGCGGCTTGAAGCTGTCGCAGAAGAAGCTGCAGCAGCACTTTGAAGAGACGGGCCATAAGGCCGACGGCGCCATCTGTGAGGTGTGTGGCGCCGAGTTTCCCTCGAAGAATGCCCTCTATCAGCACATCATTCGTGTGCATAAGCGGGACAATTTCTTTGAGTGCCACATTTGCCATAACCGCTTCACACTCAAGGCCAATCTGGAGCGGCACGTACAGCTGCACACGGAGGTGAAGCGCACCTATGTGTGCGATCTGTGCGGCTCCTCTTACTTTACATATCCTGCACTCAAGGAGCACTACAGCAATGCCCACGTGGATGTCTCCGAGTGCAAGTGCACGCTATGCGGCAAACGCTTTGGATCCGCCAAGTCACTGCAGCGGCATCTGCCTTCGCACTCCGAGGAGCGACCGCATTGCTGCAACCATTGCGATCAGACCTTCAAGTGGAAGACGCATTTGGTTCGCCATAAACAGACAATGCATGGAAATCAGCCGCCGCCTCCTAAGAAGGGCAAACAGCGTTTCCCCAAAGCCAATGAGGATGATATGGTACCTCTGCCCGATATGCCAGGTCCGCCTCCGGTGAAGGCAACCAAAAAGTCAGCTGGCAGCAAGGCAAAGTCTCAGACATCGTCGGCAGCTGCAGCCGGATCACAGCAAGGACCTGGCAAGGGTGTTGGTGGTATGGGAGCCACGCCTACACCGCCACCTCCGTTGTCAACGACGCCAGGTTGTTCGCAGCAAGATCAATTCAATGCCGCCATGGTAAGCAGTAACAGTTCGCAATCTTCAACGGCATCCACGTCACAGCACTCGGTATCGACGAGCGAATCTCAGCAGAATTCCATGTACAATCAGAGCTTTAGTGCGGAcaaattgcagcagcaaccgACGCcggcgcagcagcaacagaatgcgctgcatcagcaacatcaacaacagcagcagcaacaacagcaacaacaacatgctaCAGCGACGCCACCACCAACTCTGCAGCAACCGGTGgcaccgccaccaccgcctcagcaacaacaacagcaacagccgcaTCATCGCCATACGCATACACCGAACAACAGTACGCCGGAGTTGCACCTGCAACGCATGAACAGCTTTGGTGGGCAGGAGAGTCAGTTCCACTTTGAGCCAACTGGCAATCCAGCAAGCAGTTATCAGCAGCATCAGTTGATTAATCAgtatcaacaacagcaacaacagcaacaatcgcaacagacgcagcagcagcaacagcaacatttgcgCAGTCACACGCCTCAAAGTCCACATCCGCATCCCCATCCACATCCGCATTCGCATCAGGcacagcagttgcaacagcagcagcagcaacaacactttaGCTCACCGCACCACATGCCACCAATGCACCACCAGCATCAACTGATTCTGCAGCAACATCGTCACAGTCACTCGCCTCAGCATCAACACTCGCGATTGCAGTCGCCACAGCCGCAACCGTCACCATCCGCAGCGGCAACTgggccgcagcagcagcagcaattcatgcagcagcaacaacaggcgGCCGACTCGTGGGGCAACATGGGTTTTGGCGGTGCTCCAAACAGTCAACCAGTTGAGCTCAAGGACAACAAGTTCTACATTGTTGATTCGACCGAGTTTCTTGGGCTTCCAATGAATGTCGGCGCCACAGCGTCGCCCTCACAGCAACAACCGGCCGTTGTCAACAAGccgcaacaaccacagcagcagcaacaacagcaacaaccacagcaacagcagcagcagcaaccacaagaTCCAGCGCTGTCTAGTGATTTATTGAGCTTCCAGCACATGTGGCCACAACAGgtgcagccacaacaacagcaacagcagcagcagcagcaacaacaacagcagcaagcgGCAACACCACAGCCGCAGGCTAATCAAGTCGGACCGGGAGATGCTcataattacaacaacattGGCAGTATTCTCACGAATCTCATTGACACAAATCCCACGCCATTGGAGTACAACTTTGATctaatgcaacaacaaccgccacagcagcagcaacaaccacagcagcaacagcaagcggcacaacaacaacaacaacaacatcacaaTGCCAGCAGTGCCTATGGAGGTGGTTTAATGAGGCACGCGGCTGCTGGAAACGTTTATGGTGGCGCTGTTTCCTACGAGCAACATCACAATCACAACCACAGCGGATTGAGTGAGCAATTGGTCAGCGAACAGCAGAAGCATAACAGCTTTCAGCCATATCATGGTCATCCCCATGCACATGGACTGCAACAGCCGTTGCATTCATTAGCAGCTGCCACACACCTgttgccaccgccgccgccacaTGGTAGCGTGTATGAACGGGCGGCGGTGCCGCCAGTGGGTGTCGGAGTCGGTGTGGGTTATCCCATGTTGGGCGATGATTCAAAGTCCGTGCTGCCACCGATCAATGACTACATGCATcatatgcaacagcagcagcccgATCTAATCTATTATCCAGTGAAGAACGATTGA
Protein Sequence
MDNKTTQLDFKLLVDQSVNLLDSLNAASRCDAIKFLLQTLKCKYPEACDRVVRNLFSHKPNDNGADTESESESKQLAKSKQLQLLLATKKEKTEPGTIIDGSVSVSKIKCESDNEASSAIDLNQNFEKILCKEEFMCLDEEDDFLNDEDADADNDGDADVDVDADTENSSSMSKRLHFHRSASGSNNVDAITAAGLLTSDPLDLIHSAAAASGLVKRKYVATFDEEEDEEDEEDDETDDVENESNSNSCEELLLRRQQKLIRSRALVKRKRTNNIISNMDAVAPVARSRLGEGYVFHEDTQYTLRYHHSSGEFSERAFKAQFRVLLRLALSQHHKPFLKQFYDNFVVTGRLLGTTPATRVLKELREQRLDEWRRQRERRQQAKEAAAAAVAALRELEEKRKLKQSQPLVQQLEVPLQLDNQEPRQLRSISFGDSELESETESQLSSAAQEIMKFEEFIDEGVGAGRLIDGLEMEPEIDEMLAGAGSGLGSVTGTGSGNSNSNSSAVHDNGIASLLMDTNHGTQLHSHHLSSSSTSVGGNLVINGLTSSNINNNNNCNKSNNVVNQQLGQEHPSKQSQQLQSQSPHLSMPVRSAYGHEGVAMSATAQLMSGTEIQLQNDNPNHYNSSNNPLSMMGGMMQMQQQQQQQQQQFPQHQHAQMLNNHQPHLHPHPHPHQQSQAAHLSSSVIGSNACGQLNSSLELDDNELSGDEDDDDLDNELDEMDAAKQQLIDGGSSSSTSLQAPPSQLGGGHTPGSKKDKPSYNCLLCPKSYRKRKSLLDHYKMHPGYCHDCGQPNGNTLEEIIQHNRTMHVKEFPFVCETCGESYSRRQQFHAHVESHKKEFKMFPCGECGLKLSQKKLQQHFEETGHKADGAICEVCGAEFPSKNALYQHIIRVHKRDNFFECHICHNRFTLKANLERHVQLHTEVKRTYVCDLCGSSYFTYPALKEHYSNAHVDVSECKCTLCGKRFGSAKSLQRHLPSHSEERPHCCNHCDQTFKWKTHLVRHKQTMHGNQPPPPKKGKQRFPKANEDDMVPLPDMPGPPPVKATKKSAGSKAKSQTSSAAAAGSQQGPGKGVGGMGATPTPPPPLSTTPGCSQQDQFNAAMVSSNSSQSSTASTSQHSVSTSESQQNSMYNQSFSADKLQQQPTPAQQQQNALHQQHQQQQQQQQQQQHATATPPPTLQQPVAPPPPPQQQQQQQPHHRHTHTPNNSTPELHLQRMNSFGGQESQFHFEPTGNPASSYQQHQLINQYQQQQQQQQSQQTQQQQQQHLRSHTPQSPHPHPHPHPHSHQAQQLQQQQQQQHFSSPHHMPPMHHQHQLILQQHRHSHSPQHQHSRLQSPQPQPSPSAAATGPQQQQQFMQQQQQAADSWGNMGFGGAPNSQPVELKDNKFYIVDSTEFLGLPMNVGATASPSQQQPAVVNKPQQPQQQQQQQQPQQQQQQQPQDPALSSDLLSFQHMWPQQVQPQQQQQQQQQQQQQQQAATPQPQANQVGPGDAHNYNNIGSILTNLIDTNPTPLEYNFDLMQQQPPQQQQQPQQQQQAAQQQQQQHHNASSAYGGGLMRHAAAGNVYGGAVSYEQHHNHNHSGLSEQLVSEQQKHNSFQPYHGHPHAHGLQQPLHSLAAATHLLPPPPPHGSVYERAAVPPVGVGVGVGYPMLGDDSKSVLPPINDYMHHMQQQQPDLIYYPVKND