Basic Information

Insect: Drosophila innubila
Gene Symbol: -
Assembly: GCA_004354385.1
Location: NW:7811943-7814905[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 3e-05 0.0017 18.3 2.5 1 23 501 523 501 523 0.97

2 7 2.3e-05 0.0013 18.6 0.3 1 23 529 552 529 552 0.98

3 7 0.0059 0.33 11.1 0.7 1 23 558 581 558 581 0.90

4 7 9.1e-05 0.0051 16.8 0.4 3 23 619 639 618 639 0.97

5 7 0.00028 0.016 15.2 1.9 1 23 645 667 645 667 0.98

6 7 0.00011 0.0064 16.5 0.8 1 23 673 695 673 695 0.98

7 7 0.0084 0.47 10.6 4.2 1 22 701 722 701 725 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	3e-05	0.0017	18.3	2.5	1	23	501	523	501	523	0.97
2	7	2.3e-05	0.0013	18.6	0.3	1	23	529	552	529	552	0.98
3	7	0.0059	0.33	11.1	0.7	1	23	558	581	558	581	0.90
4	7	9.1e-05	0.0051	16.8	0.4	3	23	619	639	618	639	0.97
5	7	0.00028	0.016	15.2	1.9	1	23	645	667	645	667	0.98
6	7	0.00011	0.0064	16.5	0.8	1	23	673	695	673	695	0.98
7	7	0.0084	0.47	10.6	4.2	1	22	701	722	701	725	0.91

Sequence Information

Coding Sequence: ATGGCCACAAAATACTGTGCGCTCTGCCGTAAGAGAACGACGGAAAGGAATGTTTTAGTACCACGTGACGACAGCAGAAGGGAGCTCTGGTCAAGGATCACAGGCGTTCAATTTACGCGCTCTAGTAGAATTTGTGGCAGCCATTTCAATGATTCTGACTTCTTTTACTACCCGTCCAACAATGCAAATAAACGGAGACGTCTTCTGCCAACAGCTGTACCCCAAAAGCCAGGAGCCAAGCAAGTGTTCACAGAACATATGCCATCAGCATAttttttcagttttccaaAAAATCCGGATGTTTTAAAAAGTTGGCTCACATTTTGCcgcaagaacaacaatgacaaGATAAAGCCATACCAAAAAAGCGTCATTTGCAATGAGCACTTTAAGGAGGAGGACATCCAAGGAGGATTGCAATTTCAAATGGGATTGTGCTCGAAGAGAACGCTGAGACCAGGCGCCGTGCCATGcatcaataaaaatgatatgAGTGAGGCCGAACGGGAGAACTCGGAAAAGCGCAAGAACAAATTGTTGGTCGCAGAGCTGCTCGAGGAAGCGGAAGCGCGGGAGGCGGCCGAGGCTAGTGGAGAAATTACAATTGCCCCTGACTTTGTCCGAAATACAGGCATTGTCTCTGTTCCCGATTTTGTTAGCGCCACTGGAAATGCCTTCGTTCCATTCACACCCGCACCTACAGATACAGATCCCTTGGCTGAGGAGCAATCGGAGGCTGATATTTCCACAAGTAGCAGTAGAAAGGATGTTACTTTAATCAATAAGAACAAATGCCGCACCTGTTCTCGTCCCTTTGTTGTTGACGAAAATGCCAAAGATCTGTGCAACGAGGAAAACGCAGTCATGTTATATCACATAGAAGTTATTACCGGCATTTGGatCCAATGCAACGATGAAATTTCGCGATTCATGTGCTCCAAGTGTGTGGACAAGTTGCGCACAGCCATTGAGTTCCGGGAAATATGCATTCGTACAGAGCTGCTGCTTACAGGTGGCGACGATGTTGAACTTCCGGAGAACGACATGGAACTGTGCGATAGTGATAAGGGGGAAGCGCAGTTGATTGACCATATAAAAGAGGAGGAATTTATTTCAGTATTTCCGGGTGAGGAGGAAGATGGATTAACAACTGTAATTGAGCCGTTATCAGGATCAGTAACTAAAAAAATCGGTCAGGTATTACATCCGGCGGCAGTGGATTCAAGTAGTCTTGCTCTGGGTGCCCAGATCTATGAAGatcttttaaatgaatatctAGGAAAGGAGAAGAAACCGCGACCCAAACAAAAGACGGCAATAAACCCAAACGGGAAAGAAGAAGACACCACGACCAAATCAAAAGTCGACAATAATTCCAAACGCCCATCCGTgagacaaagacaaaaaaagCCTGGGGAGCCAGCGCCCAAGCGTACAAGACGCACGAAAGAGGAAAAAAATCGGATTCGACGTGAACAGATCAGAGCCATGCCACTCAATCACGTGTGCGATCAGTGCGGAGCATCTTTCCGGGTGAGATGCAATCTGACAATACACATGCTGAGACATACGCACACCAAAAACTACGAATGTCCCGAATGCCCTAAGAAGTTCTATGATGCATACATGAGGAACATGCATATCCGTGTGCGTCACAAGGGGGAGCTTCCGTTTGTCTGCAATTACTGTCCGCAAGCATTTAGTTCATCCAACACACGTTATCTGCACGAGAAAAACGTTCATGGAGCATCTCCACGCATTCATAGAAATGTGAATAAATCGAATCCATGGAATGAACGCAAAGCAAGTAAAACGCAGCCGGATTCACTGCCAAAGGAAACTGTCCGTAACTTTTGCATGTATTGCGATAAAAGCTATGCCACGAAATACGCGCTGAACGGACATATCAATCAGCATTTGGGTCTTACTCCTTATAAGTGCAAAAAATGCGATATGAGATTTGCGACACCTCAAGCTAAAAAGAAGCACGAGATGAGGCACGATAGTAAGCGTCCCTTCGAGTGTGACATTTGCCTCAAAGGATTCTACACACGCACCAAGCTTAAGGAGCATGAACGGATTCATACGGGCGAACGTCCTTACAGATGTGACCTCTGCGATGCATATTTTAGATACAAGTTCAACTTGCATTCGCATCAGTTCAGTAAAATGCATAAGGACAATCTGAAAAAGGCGCAAAGCGAGAAAATTATCGAAGACTCAAGTTAA
Protein Sequence: MATKYCALCRKRTTERNVLVPRDDSRRELWSRITGVQFTRSSRICGSHFNDSDFFYYPSNNANKRRRLLPTAVPQKPGAKQVFTEHMPSAYFFSFPKNPDVLKSWLTFCRKNNNDKIKPYQKSVICNEHFKEEDIQGGLQFQMGLCSKRTLRPGAVPCINKNDMSEAERENSEKRKNKLLVAELLEEAEAREAAEASGEITIAPDFVRNTGIVSVPDFVSATGNAFVPFTPAPTDTDPLAEEQSEADISTSSSRKDVTLINKNKCRTCSRPFVVDENAKDLCNEENAVMLYHIEVITGIWIQCNDEISRFMCSKCVDKLRTAIEFREICIRTELLLTGGDDVELPENDMELCDSDKGEAQLIDHIKEEEFISVFPGEEEDGLTTVIEPLSGSVTKKIGQVLHPAAVDSSSLALGAQIYEDLLNEYLGKEKKPRPKQKTAINPNGKEEDTTTKSKVDNNSKRPSVRQRQKKPGEPAPKRTRRTKEEKNRIRREQIRAMPLNHVCDQCGASFRVRCNLTIHMLRHTHTKNYECPECPKKFYDAYMRNMHIRVRHKGELPFVCNYCPQAFSSSNTRYLHEKNVHGASPRIHRNVNKSNPWNERKASKTQPDSLPKETVRNFCMYCDKSYATKYALNGHINQHLGLTPYKCKKCDMRFATPQAKKKHEMRHDSKRPFECDICLKGFYTRTKLKEHERIHTGERPYRCDLCDAYFRYKFNLHSHQFSKMHKDNLKKAQSEKIIEDSS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00528840;
90% Identity: iTF_00507162;
80% Identity: iTF_00522990;