Basic Information

Insect: Drosophila innubila
Gene Symbol: sug
Assembly: GCA_004354385.1
Location: NW:21554057-21555628[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.00061 0.034 14.2 0.1 1 23 129 154 129 154 0.92

2 5 4.3 2.4e+02 2.1 0.3 3 23 166 191 164 191 0.73

3 5 1.3e-07 7.3e-06 25.7 4.0 1 23 197 219 197 219 0.98

4 5 0.0001 0.0059 16.6 4.5 1 23 225 249 225 249 0.99

5 5 9.7e-06 0.00055 19.8 1.0 1 23 255 281 255 281 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.00061	0.034	14.2	0.1	1	23	129	154	129	154	0.92
2	5	4.3	2.4e+02	2.1	0.3	3	23	166	191	164	191	0.73
3	5	1.3e-07	7.3e-06	25.7	4.0	1	23	197	219	197	219	0.98
4	5	0.0001	0.0059	16.6	4.5	1	23	225	249	225	249	0.99
5	5	9.7e-06	0.00055	19.8	1.0	1	23	255	281	255	281	0.93

Sequence Information

Coding Sequence: ATGGATATATTAGTACAAAAGCCAATCTTCTGCCACAGCAGCGAGTTCTACGAGCCGCCTCCGAGTGATTACTTTACGCCGTACAATACGCCGCCGTACATAACATCGCATCCGCAACCGCAACCGCATCCGTATCTAAGTTCAGGAGCTGCTTCCGGAAGCTGGCTGGGCGAGCAGATGCAGTACCTCCGATTTCCGACGCCGCCCATAACACCACCGAGGATTGTCGTTCCCGTTCACGTTCCCCTTGCCACACAGTCCGAGACCAGAGAGTCCGTCATCATGAAGTGCACAAAGAGTTCCAGTTCCGGTTCCGGCTCCGGCTCCGGCTCACGCTCTCCGACGGAGTCCTGCAGCGAGcagagcagcggcagcgagTGCGACTTTAACTGCAATTGGCAAGATTGCGGCAGAGTGTTTGAATCGTTGGAGGCACTTGCTCAGCACGTCACATTACGTCATGCGATTGCCTCATTATTGGATGGACTCTATTATTGCCGCTGGGGCGGCTGTCAGCGCAGTGAACGTGGCTTCAATGCCCGCTACAAGATGCTCGTCCATGTGCGCACCCACACCAAGGAGAAGCCGCATCGTTGCCATCTCTGTGAGAAGTCCTTTTCCCGAGCGGAGAATCTCAAGATTCACATACGCTCGCATTCGGGCGAGAAACCGTACAAGTGTCATTTCGAGGGCTGCCAGAAGGCTTACTCCAATTCATCGGATCGCTTCAAGCACACACGCACTCACTCCATGGAAAAGCCGTATATGTGCAAGGTGCCCGGCTGCCAGAAACGCTACACGGATCCTTCGTCCTTGCGCAAGCATGTGAAGACGTTCAAGCACAGCATTCAGCTTATTGCCAGCCAAAGTTCCACCTGTCTGCTGGATGCCACCGAGCACTCATCGTCCTACACTTGCCTGCCTCTGACTGCACCCGTATCCGTATCCGTGCCCCTGTCCACTTCCTGTGTGGAGTCGTCACCCAGCTCTCGCTGTTATGACAGCGACAATGTCGCTAGCGATTATTCGCTGAGAGCCAAGCATCATAACGAGTACACATCCTCCGATTACTGGCTACATCCGAGGGAGCACAGCTATCGCTATCTACATAGCGAGGACTATGCTATGAATATGGATCTGGACACGCCCACGCCGCTCGATCTGCGCATCCATAGAAGTTGA
Protein Sequence: MDILVQKPIFCHSSEFYEPPPSDYFTPYNTPPYITSHPQPQPHPYLSSGAASGSWLGEQMQYLRFPTPPITPPRIVVPVHVPLATQSETRESVIMKCTKSSSSGSGSGSGSRSPTESCSEQSSGSECDFNCNWQDCGRVFESLEALAQHVTLRHAIASLLDGLYYCRWGGCQRSERGFNARYKMLVHVRTHTKEKPHRCHLCEKSFSRAENLKIHIRSHSGEKPYKCHFEGCQKAYSNSSDRFKHTRTHSMEKPYMCKVPGCQKRYTDPSSLRKHVKTFKHSIQLIASQSSTCLLDATEHSSSYTCLPLTAPVSVSVPLSTSCVESSPSSRCYDSDNVASDYSLRAKHHNEYTSSDYWLHPREHSYRYLHSEDYAMNMDLDTPTPLDLRIHRS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00608735;
90% Identity: iTF_00529101; iTF_00507166; iTF_00575898;
80% Identity: -