Basic Information

Insect: Drosophila innubila
Gene Symbol: ham
Assembly: GCA_004354385.1
Location: NW:19834716-19857444[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.25 14 6.0 0.1 2 23 328 350 327 351 0.92

2 9 0.044 2.5 8.3 0.6 3 23 359 380 358 380 0.90

3 9 1.4e-05 0.0008 19.3 0.3 1 23 386 409 386 409 0.96

4 9 3e-07 1.7e-05 24.6 1.5 1 23 415 437 415 437 0.97

5 9 3.8e-05 0.0021 18.0 4.7 1 23 443 465 443 465 0.98

6 9 0.011 0.61 10.2 1.6 3 21 474 492 472 493 0.93

7 9 5.9e-09 3.3e-07 30.0 1.3 1 23 979 1001 979 1001 0.99

8 9 1.3e-07 7.5e-06 25.7 1.1 1 23 1007 1030 1007 1030 0.97

9 9 5.8e-06 0.00033 20.5 3.1 1 23 1036 1058 1036 1058 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.25	14	6.0	0.1	2	23	328	350	327	351	0.92
2	9	0.044	2.5	8.3	0.6	3	23	359	380	358	380	0.90
3	9	1.4e-05	0.0008	19.3	0.3	1	23	386	409	386	409	0.96
4	9	3e-07	1.7e-05	24.6	1.5	1	23	415	437	415	437	0.97
5	9	3.8e-05	0.0021	18.0	4.7	1	23	443	465	443	465	0.98
6	9	0.011	0.61	10.2	1.6	3	21	474	492	472	493	0.93
7	9	5.9e-09	3.3e-07	30.0	1.3	1	23	979	1001	979	1001	0.99
8	9	1.3e-07	7.5e-06	25.7	1.1	1	23	1007	1030	1007	1030	0.97
9	9	5.8e-06	0.00033	20.5	3.1	1	23	1036	1058	1036	1058	0.98

Sequence Information

Coding Sequence: ATGTTATGCGATCGTTTTGTTATATCAGGCTCAAACGGCGAGGACTTTGATCCGAGTGTCGTgcggcatcatcatcatcttctgCATCATCATTTGGATCTCAATAGTGCGACGCCGGGATTTGGACAATTGCCGCCGGCGCTTTTAAGTGGCAGTCCGTCGAGGCCGGAGGAATCGTTTGCTCGCCATCTGCCACCAACGATATCCCCCTCAACGCCCCCGCCGCCGCCCACCTCAGCCATGCAACGTTCGCAGGAGACGCAGCAGCGTCTCATGGCTCTCTCCGCCTCCACTCCGCTCTCCTCCTCGGCTCTGAGCAATGGCTCCGGTTCCGGCTTGGAGCACTTGTTCAGCGAGGAGCAAAAGGAACACCTGCTGGACATGGCGCGTCTTCGGGAGCCCGTCTCCAACCTGGACATACGTGATACTGGCGTCTATGCCAAGACATATCTGCCACGCGGCACCCGCTACGGACCCTTCCCCATGCGTCTCTGCCAACAACCCAGCGATCGTCATCTGGCTTGGGAGgTGATTGCCGGCCCACTTTTTCATGGCTGGCTGGAACCCTCATCCGATGTGGCCACATGGCTGAAAAAAATACGCGCCGTGCAAATCGATGAAATTGAAGAGGctaatttaaagaattttatatttgacgGCTATctGTGGTACGAAACCAAACGGGATGTGAATGCAGGCGCTGAAATTGTGGTCGATGGACGTCCCAAAACTCCCTATGATATCAGTGAGAATAGTATGGCAACTGCTGCGGCTGTtacagcagcagtggcaaaaGTAgccaacaagaacaacaacaacaatagcaacagcaataacaacaacaatagcttaTTAAGCAACGATGATCGCAGCGATCGAGATAATGgTTCCCATTATAGCAGCGACGAGTTTaccaaagagaaaaaaaacttatcGCAGGGCGATATCGATTTCACAGACGACGAAAACGCTATCGATATACGCTGTGAGGTCTGTGATAATGTCTATACGGATTTAGAACGCCTGGATGATCATTTGGTGGTCCAACATCATTTTAAACGCGGAGAAGTTGCCTGCGAGCTTTGTGGCCAGCGTTTCTGTCATCGTCCATTGGTGATCAAACACGGGGCAATCGTACATAATAATTCACGCAAATATTCCTGCGAGAACTGTTCCAAGGTATTCCGTGACCCATCGATTTTACAGCGTCATATTCGCGCCTATCACGTTGGAGCTCGCAGTCACCCGTGTCCGGAGTGCGGCAAAACATTTGCGACATCGTCGGGTCTAAAGCAACATCAGCACATCCATTCGTCGGTGAAGCCCTTCTCCTGTGAGGTGTGCTTCAAGGCGTACACACAGTTCTCGAATCTGTGTCGTCATCGGCGCATGCACGCCGATTGTCGTGTCCAGATCAATTGCAAGAAGTGCAACACGAGCTTCAATTCGGTCACCTCGTTGTCCAAGCACAAGAAATTCTGCGATACAACGGATAGCTTTCGCAGTCAACAGAGTCGcctgcatcatcatcatcaccatcacaGCCATCATCACCAGCAggagcggcagcagcagcagcagcagcagcaacaacagcagcaacagcaacaacaaccgtcAATTCCACTGTTGTTGCCACCAGGAGCACATCAACGCCTTGCCGTCGGCAATAGCTCGAGCTCAAGCAGCGAGTCCAACAACTCTGCCATGGCCACTCCACCGAATCATCTATTTATGTTGCGTCCCAGCACATCGTTCTTTCCGGGATTCCCCCACTACGGATTGCCCAATTTCTTTCAGCAGGCTGGCAACTTCCCCTTGCCGCACATGTTCCCCAATCCGCAGCTGGCGGAGATGGGACGAGGCCTGGCCCCTTTGGTCTTTGGTCCCAATGCCGCAttccaacagcagctgcaggcGGCAATGAACATCAAATCGGATTCACCGCCATTAAAACATGAATCCAGCTCACCGGAGCAAAAGCCCATCAAATCCGAACTTCAGGCATCCGACGAAGAAGAGGAGGAGCAGGACCGGGAGGAAGAGGAACAGTCCAGTTACGAATTGGAGTCCAGCAAAGTTAGGCCGAAATCGACAAAACTGAAACGGGATACGGGAAAGGTTAAGCGGGAGCTCAAGTCGGAGACAAATTCCGCACAGCAGATCGAGGAGGAGAACGACCTTGAAAATGACAGGAAATCCATTGACATTGTTAGCACTCCGCCGCCAACAGAGGCTGAAACAGAGGAGTTGCAGCCGGAGAAAAGCAGCGCGGAGCAGCCTCTGGATCTGTCCGTCAGTCGCAAGCGTCGCAGCTCTGTTTGCAACAGTTCCACGCCCGCCCCGCTGTCCATTTGCATGTCCAGTCGGACACCCACACCCGACCTGGAGGCGGATGAAGATGTGGAGCTACTGCAGCCGCCGCCGACAAAGATGGCGAAACACAGCTCAGGGGAATCTTCGACGTCACGGCTGTCGTACAAGGGCAGCAGTCCGACGCACAGTGCCAGCGCCTCGCCAGGACCCAACACCTCCCCCTCGCCACCGATTAGTACGGGCGGGGATCTGAGCAGCATGTCGGAGAGTGCAGCGGCATCTGCGGCATCAGCGGCATCGGCGGCTGCAGCGGCTGCTGTTTCGGCCATGACTTGTCCAAGGCCACAGTTGGCTCCACAGCTGTTGCTGGAGGAGTTTTATCGCACACGCTTCTCACCGCAACAGATTCCTTTTTTAGGCCGAATGGGCGGACGGCCAGGTTTTGAGCTGCCAGTTGCAGGTGCGCTTGCACCGATGAGCAGCTCGCGTCATCTGTCGTTTCCGCCCGAGCACAATTTCCGTGAGGCATTCCGTGCCGCCGGCCTGCCCGCCTCCCGCCCCCATGTGGCTGCCACATCCAGCAACATGGGCCGTGGAGGCGACAAACTCAAGGATCGCTACACCTGTAAGTTCTGTGGCAAGGTATTCCCTCGATCCGCAAATCTAACCCGACATCTTCGTACTCACACCGGGGAACAGCCTTATAAGTGCGATTACTGCGATCGTTCCTTCAGCATCTCATCGAATCTGCAGCGTCACGTGCGCAACATCCACAACAAGGAGCGTCCCTTCCGTTGTCCCATGTGCGATCGTTGCTTTGGCCAGCAAACGAATCTCGATCGGCATGTGAAGAAGCACGAGGCGGATGCGGTGGGAATCGAGTTTAACGATTCCCCCAGCTCCAATGAGGCCAAGGATCGCGAGGAGACCTACTTTGAGGAAATCCGATCCTTCATGAAGGGCGTCTATACGCCCAGCAGTCTGGGCGGGGCCGATGGCGATACCGAGGAATATGCCGGAAGTGATGATCAGTTGTCAGTGTCGACGCGGCAATCGGCCAACTTTGATAAGGAATTGCTGGcacatggcaacaacaataataataacaacaacaacaacagcatcaataatgagaacaacaatagcaacagcagcagcaacaacaacaacaacaccaccaataccaacaacaatcagGCGGGCTTGGGCGAAACAATTGCCGTTAGCACCtaa
Protein Sequence: MLCDRFVISGSNGEDFDPSVVRHHHHLLHHHLDLNSATPGFGQLPPALLSGSPSRPEESFARHLPPTISPSTPPPPPTSAMQRSQETQQRLMALSASTPLSSSALSNGSGSGLEHLFSEEQKEHLLDMARLREPVSNLDIRDTGVYAKTYLPRGTRYGPFPMRLCQQPSDRHLAWEVIAGPLFHGWLEPSSDVATWLKKIRAVQIDEIEEANLKNFIFDGYLWYETKRDVNAGAEIVVDGRPKTPYDISENSMATAAAVTAAVAKVANKNNNNNSNSNNNNNSLLSNDDRSDRDNGSHYSSDEFTKEKKNLSQGDIDFTDDENAIDIRCEVCDNVYTDLERLDDHLVVQHHFKRGEVACELCGQRFCHRPLVIKHGAIVHNNSRKYSCENCSKVFRDPSILQRHIRAYHVGARSHPCPECGKTFATSSGLKQHQHIHSSVKPFSCEVCFKAYTQFSNLCRHRRMHADCRVQINCKKCNTSFNSVTSLSKHKKFCDTTDSFRSQQSRLHHHHHHHSHHHQQERQQQQQQQQQQQQQQQQPSIPLLLPPGAHQRLAVGNSSSSSSESNNSAMATPPNHLFMLRPSTSFFPGFPHYGLPNFFQQAGNFPLPHMFPNPQLAEMGRGLAPLVFGPNAAFQQQLQAAMNIKSDSPPLKHESSSPEQKPIKSELQASDEEEEEQDREEEEQSSYELESSKVRPKSTKLKRDTGKVKRELKSETNSAQQIEEENDLENDRKSIDIVSTPPPTEAETEELQPEKSSAEQPLDLSVSRKRRSSVCNSSTPAPLSICMSSRTPTPDLEADEDVELLQPPPTKMAKHSSGESSTSRLSYKGSSPTHSASASPGPNTSPSPPISTGGDLSSMSESAAASAASAASAAAAAAVSAMTCPRPQLAPQLLLEEFYRTRFSPQQIPFLGRMGGRPGFELPVAGALAPMSSSRHLSFPPEHNFREAFRAAGLPASRPHVAATSSNMGRGGDKLKDRYTCKFCGKVFPRSANLTRHLRTHTGEQPYKCDYCDRSFSISSNLQRHVRNIHNKERPFRCPMCDRCFGQQTNLDRHVKKHEADAVGIEFNDSPSSNEAKDREETYFEEIRSFMKGVYTPSSLGGADGDTEEYAGSDDQLSVSTRQSANFDKELLAHGNNNNNNNNNNSINNENNNSNSSSNNNNNTTNTNNNQAGLGETIAVST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00537666;
90% Identity: iTF_00507107;
80% Identity: -