Basic Information

Insect: Drosophila innubila
Gene Symbol: -
Assembly: GCA_004354385.1
Location: NW:3542852-3545311[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0037 0.21 11.7 4.5 2 23 226 247 225 247 0.97

2 12 0.00059 0.033 14.2 4.0 1 23 253 278 253 278 0.95

3 12 0.00059 0.033 14.2 0.4 1 23 285 310 285 310 0.95

4 12 0.0015 0.084 13.0 3.5 1 23 318 340 318 340 0.97

5 12 6.4e-05 0.0036 17.3 0.9 3 23 349 369 347 369 0.98

6 12 0.0001 0.0056 16.6 0.1 1 23 375 397 375 397 0.98

7 12 0.15 8.6 6.6 7.6 1 23 403 426 403 426 0.98

8 12 0.031 1.7 8.8 5.7 1 23 432 454 432 454 0.94

9 12 9.6e-05 0.0054 16.7 2.1 1 23 460 482 460 482 0.99

10 12 7.3e-06 0.00041 20.2 0.4 2 23 564 586 563 586 0.96

11 12 0.00035 0.02 14.9 4.7 1 23 592 614 592 614 0.96

12 12 5.4e-05 0.0031 17.5 2.2 1 23 620 642 620 642 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0037	0.21	11.7	4.5	2	23	226	247	225	247	0.97
2	12	0.00059	0.033	14.2	4.0	1	23	253	278	253	278	0.95
3	12	0.00059	0.033	14.2	0.4	1	23	285	310	285	310	0.95
4	12	0.0015	0.084	13.0	3.5	1	23	318	340	318	340	0.97
5	12	6.4e-05	0.0036	17.3	0.9	3	23	349	369	347	369	0.98
6	12	0.0001	0.0056	16.6	0.1	1	23	375	397	375	397	0.98
7	12	0.15	8.6	6.6	7.6	1	23	403	426	403	426	0.98
8	12	0.031	1.7	8.8	5.7	1	23	432	454	432	454	0.94
9	12	9.6e-05	0.0054	16.7	2.1	1	23	460	482	460	482	0.99
10	12	7.3e-06	0.00041	20.2	0.4	2	23	564	586	563	586	0.96
11	12	0.00035	0.02	14.9	4.7	1	23	592	614	592	614	0.96
12	12	5.4e-05	0.0031	17.5	2.2	1	23	620	642	620	642	0.98

Sequence Information

Coding Sequence: ATGACTGAGGAGACTTCACCCTCAATACATACAGTTTGCCGTACTTGTTTGTCCAACCTGCAACACAATGAAGCCTTTGATCTGTTTGTTGTTCCGGGACTCGCCAAGAAGTTGTGTGTCTGTACTTCGCTGTCGGTGGAGCACCTGGATGGATTCCCCAGAAACCTCTGCACCACCTGTCACAGCCGTCTTAATGATTTGCATGACTTTCAGAAGCAATGCGTGGACTCTGTGCAAAAATTTAAGGAGTTAATATCCAGCACCTGTATTGTAATCACAACTATTCCGGAGGACGATCCTGGCGTCGTGGATGCTGCTGTGCAGGATGTTGTCCATGATGAGGAGCACATTAATTTCGACCCACTGTTGGATACAAAAATGGAAGTTGACAACGAGGCGgatgtttttaaaatgattgaaGATGTTGACAAGGAATCCGAGGAAGTAGATAATCAGGAGGATGCATTTAATGACAGCGGAAGCGACTATAACAATGAAGATGCGGACTTCCAAGTGGATAGCAGCGATTCCGATGATGAGATGCCGTTGTCCCGCCTGCGAAGTACTTCAAGAGCCACAAAGTCCAAGACCAAACAGGATGATAAGGATAAGTCTAAAGAGAAGCCGAAACGTAAGCGGATTCCAGCTGCTGAGCGTGAGCTTCATCGCTTAATCGAGTGTCACATTTGTCGCCAGAAGTTCAAGAAAGCAGTATGTTATGAGGAGCATATGAAACGCCACAATGATCTCTTGCCATTTCAGTGTACAGTGAAAAAGTGCCAGAGGGGATTTACGACTTCCACAGGACTGAAACATCATATGGAGCATGCACATACGGAACTATGCGATCTTCATCCCTGCACAGTCGAAGGATGCAACGAAGCCTTTGCTCAAACTCGCATGCTCACTCAACATCTGAGGAAGGTGCATAATATTGCCAAACCGGAAATCCATCCATGCTCCGAATGTGAGAAAGTATTCCGTTGTCCAATGGCATTGAAGAAGCACATGTATAAACACACTGGCGAGGAACTTCCATTCGGCTGTAACATCTGCCAGAAACGCTTTCGGGTCAATACTGAACTTAGAGATCATCTTTTGCGTCATGCTGGGATCAGAAACTTTGTTTGTCCTTATTGTGGCGTGGGCAGGACCACAAAACAGGAGCTGGACAAGCACATCTTGACACATACGAAGGAGAAGAAGTTCAAGTGTGATCAATGCGATCATACCTCCCACAACAAACAATGTATGACCAAGCACATCAAGGTGGTGCACATGAAGATCAGGAACTACTTATGCCAGTATTGCCAAAAGTCCTTTGCCAGCGCTTATCACTGCAAGAACCATGAGAAACTGCACACTCGGAACGATTGCTTCGAGTGCAAGATCTGCGGCAGGAAGTTTCTCTTTGAGAGCAGATTAACGAAACATTTGAGAACACATGCCAAGAAAGGTAGCAAAACCACTGCGAGCTCGACAAAGACAGAAACTGATGTGGAAACTGCACAGACGGAGTCGACAGAAGTCATGAAAGTACCAGAAATTCCAGTCAAGCCGAGAGATCCGCGTCGCATTGAGATTGTGGATATATCTCAGTTGGCTGGCACCATTGTTAATCCCATTCCATCGGTATCTGTATCCTCCTGGTCGCCGCAGGAGAACTTCACCAAGAACGAGGGCCAGATCGTTTGTCCAGACTGTGGACGAGGCTTCAACCATCTGAGCAATATGAAACTGCACTACAAAGTTGTACACGAAAAGATCAAGGACTATGCCTGTCGCTTCTGTCCCAAACGCTTCAGCAGATCTCAATATCTCCGTCACCATGAGTACACACATACGGGAGAAAAGCCATACGAGTGTAAAGTGTGTAATCAAAGGTTCAGACATGATGCCACATTGGGAAGACACATGCAATCGCACAACAGACCTCCAAAGGATCCAAAGAACCCAAAGCGTCAGAGAAAAGATCCTCAGGAGCCGAGACTGACACTGAACACGGAACCAATAATGAATTACGAACAGTACCAGGATCCAGATGCAGAGCGAGAGGCTGCAACGGCTGAGTTGGTGGCCCAACAACTCAACCGGGAGGAAGGTGATGCCAAGCCCAAGTGGGGACTAGCCAAGGGTGGGGAGGTTCAGGAGGCAGCCTGCGAGCAGCTCCAGAAGTTGCGACAGAAGCAACTCGAGAAGgtttcctatgacagcttcgCTGACCAAGTTCCCGAATCTGGTATTCGCAAGGACATAGCCAAAAATCATGTATAA
Protein Sequence: MTEETSPSIHTVCRTCLSNLQHNEAFDLFVVPGLAKKLCVCTSLSVEHLDGFPRNLCTTCHSRLNDLHDFQKQCVDSVQKFKELISSTCIVITTIPEDDPGVVDAAVQDVVHDEEHINFDPLLDTKMEVDNEADVFKMIEDVDKESEEVDNQEDAFNDSGSDYNNEDADFQVDSSDSDDEMPLSRLRSTSRATKSKTKQDDKDKSKEKPKRKRIPAAERELHRLIECHICRQKFKKAVCYEEHMKRHNDLLPFQCTVKKCQRGFTTSTGLKHHMEHAHTELCDLHPCTVEGCNEAFAQTRMLTQHLRKVHNIAKPEIHPCSECEKVFRCPMALKKHMYKHTGEELPFGCNICQKRFRVNTELRDHLLRHAGIRNFVCPYCGVGRTTKQELDKHILTHTKEKKFKCDQCDHTSHNKQCMTKHIKVVHMKIRNYLCQYCQKSFASAYHCKNHEKLHTRNDCFECKICGRKFLFESRLTKHLRTHAKKGSKTTASSTKTETDVETAQTESTEVMKVPEIPVKPRDPRRIEIVDISQLAGTIVNPIPSVSVSSWSPQENFTKNEGQIVCPDCGRGFNHLSNMKLHYKVVHEKIKDYACRFCPKRFSRSQYLRHHEYTHTGEKPYECKVCNQRFRHDATLGRHMQSHNRPPKDPKNPKRQRKDPQEPRLTLNTEPIMNYEQYQDPDAEREAATAELVAQQLNREEGDAKPKWGLAKGGEVQEAACEQLQKLRQKQLEKVSYDSFADQVPESGIRKDIAKNHV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00585379;
90% Identity: iTF_00575779;
80% Identity: -