Basic Information

Insect: Drosophila innubila
Gene Symbol: ZNF526
Assembly: GCA_004354385.1
Location: NW:12392849-12395613[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.21 12 6.2 0.3 1 21 328 348 328 349 0.94

2 10 3.5e-06 0.0002 21.2 1.3 1 23 357 379 357 379 0.99

3 10 0.00084 0.047 13.7 2.6 1 23 382 405 382 405 0.92

4 10 1.2e-06 6.6e-05 22.7 0.8 2 23 412 433 411 433 0.98

5 10 2.1e-07 1.2e-05 25.1 0.6 1 23 439 461 439 461 0.98

6 10 4.3e-06 0.00024 20.9 0.7 1 23 467 489 467 489 0.99

7 10 0.00045 0.026 14.6 4.0 1 23 495 517 495 517 0.99

8 10 0.00052 0.029 14.4 0.3 1 23 523 545 523 545 0.98

9 10 7e-05 0.004 17.1 3.6 1 23 551 573 551 573 0.99

10 10 0.00026 0.015 15.4 0.2 1 23 579 601 579 601 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.21	12	6.2	0.3	1	21	328	348	328	349	0.94
2	10	3.5e-06	0.0002	21.2	1.3	1	23	357	379	357	379	0.99
3	10	0.00084	0.047	13.7	2.6	1	23	382	405	382	405	0.92
4	10	1.2e-06	6.6e-05	22.7	0.8	2	23	412	433	411	433	0.98
5	10	2.1e-07	1.2e-05	25.1	0.6	1	23	439	461	439	461	0.98
6	10	4.3e-06	0.00024	20.9	0.7	1	23	467	489	467	489	0.99
7	10	0.00045	0.026	14.6	4.0	1	23	495	517	495	517	0.99
8	10	0.00052	0.029	14.4	0.3	1	23	523	545	523	545	0.98
9	10	7e-05	0.004	17.1	3.6	1	23	551	573	551	573	0.99
10	10	0.00026	0.015	15.4	0.2	1	23	579	601	579	601	0.97

Sequence Information

Coding Sequence: ATGGATGTGGAGAAGATTTGTCGCACTTGCTTAAGTCTTTCTGGACCATTTCTATCAATCTATGATGGCGGCAACGGCAGCTGTTTGGTCGATATGTTGCGCGAATTCACTAGGACCAAGCCGCGTTGCGAGGATAATTTACCAGCCAGAGTCTGCCTCAGTTGCATCAGCGAAATTAACCACTGCTATTCATTTAAACTCAAGTGTGAGAACTCAAATCGCACActgcggcagctgctgccaaaTGCTCTGCCCGAGGAGCCCGActttgtggcagcaacaacagcaacaacgaaaacAGAAGTCAAGCCAAAGGTGGCTACAAGAGATTCATCAGTGCAAACCAACGCTGTCCCAACATGCACAATTGAAGCGCAAACGGATGTGGTGACCACAGCGGATGCGGAGCAAAACACCAGCCTGGAGAAATCGGTGGCAATCTGTGACGAGGCCGATGATGTAGAGGAGTTTGACTATGAATTCACAGATGAGCAGGATAACGAAGAGACGCCGTCCAAAGTGAGCCCGGAAAACATAATACTGCATGTGGAGAAAGACGATATCAAGTTTGAGACGGAAATGATATATGACAAGAGCACAGGTGAGTTGCACgaacaaccaacaacacaaGGGAAACAGAAGGAGTACAAATATCGACTGGTCAGCAATGGCATTGGGAGCACATATATTGCACCAGAGCCGGCGTCAACGCCAACACTTCCTCAAGTGACAACACGCAAGAGCGCTGCCAaactgttgcaacaacaacaacagcagcagcaggagcagcagaaACAGTGTGAGGAAGACAAGCAAGAGAAATCGGGACAAGAAGATTTACAAACAACGAGCAAGCGGAGCACACGACGTCGGGCTGCAACACAGCCAGACGAATATCAGGAGTCATCGGTCAGGCCATCAAAACGAAGTGTACCAAACCAATCCATTAATGCATCCGAGACGGAAGATCTTAAGGCGAATTTCCATTGTGATCGCTGCAATGCTGGATTTGTCCTAGAGAAATCATTGATTATCCACAAGCGGCAAAACGGATGCACCAATCGCAGTTTCAAGTGCAACGAATGCGAACGAGTTTTTGTCTCCTTAAATCATTTAAACGAGCACCAGGCGACGCATGCTTCCCACAATTGTCAGGAATGCGGAGTGCGTTGTGAGTCCAAAGATCAGCTGAGCAGGCACATGGTCCAGATGCACAAACGTAATCTACGCAATCAGTGCAACGTTTGTCAGAAGGTCTTCACGATGCTCTCAACGTTGCGGGATCACATGCGCATCCACACTGGGGAGAAGCCATTTGTGTGCAACGTTTGTGGCAAGGGCTTTACACAGAATGCCAATCTGCGTCAGCACAAGCTCCGGCACTCGGACATCAAACGCTTCAAATGCGAGCTCTGCAATAATTCATTTGTGACCAAGGCGGAACTGACCTCGCATGCGCGCACACACACCGGTGTGAAGCCGTACGAGTGCGATGTGTGCTCCTCGAGGTTCACCACCAGTTGCTCATTGGCCAAACACAAGCGTAAACACACTGGCGAGCGACCCTACCCCTGTGATCTGTGCCCCATGCGATTCACAGCACTCAATGTACTAAAGAATCATCGACGCACGCACACGGGCGAGCGACCATATGTTTGTCCCTTCTGCTCCAAGAGTTTCACACAGCGTGGCGATTGTCAGATGCATCAGCGGACGCATCAGGGGGACAAGATCTACATTTGTCCAGTGTGCAATGAGGAGTTCAAGACAATGAATGAGATGCGATCACATTTGACAGTTCATGAGCAGCAGGACAAACGATTGGTCCACTTTACCCTTCTGAGCAACAAGGAGAACGGAAATGCGACGCTGGAGGAGCAAGATGATGAGTCGGATACAGCGGACACAGACTTAATGTAG
Protein Sequence: MDVEKICRTCLSLSGPFLSIYDGGNGSCLVDMLREFTRTKPRCEDNLPARVCLSCISEINHCYSFKLKCENSNRTLRQLLPNALPEEPDFVAATTATTKTEVKPKVATRDSSVQTNAVPTCTIEAQTDVVTTADAEQNTSLEKSVAICDEADDVEEFDYEFTDEQDNEETPSKVSPENIILHVEKDDIKFETEMIYDKSTGELHEQPTTQGKQKEYKYRLVSNGIGSTYIAPEPASTPTLPQVTTRKSAAKLLQQQQQQQQEQQKQCEEDKQEKSGQEDLQTTSKRSTRRRAATQPDEYQESSVRPSKRSVPNQSINASETEDLKANFHCDRCNAGFVLEKSLIIHKRQNGCTNRSFKCNECERVFVSLNHLNEHQATHASHNCQECGVRCESKDQLSRHMVQMHKRNLRNQCNVCQKVFTMLSTLRDHMRIHTGEKPFVCNVCGKGFTQNANLRQHKLRHSDIKRFKCELCNNSFVTKAELTSHARTHTGVKPYECDVCSSRFTTSCSLAKHKRKHTGERPYPCDLCPMRFTALNVLKNHRRTHTGERPYVCPFCSKSFTQRGDCQMHQRTHQGDKIYICPVCNEEFKTMNEMRSHLTVHEQQDKRLVHFTLLSNKENGNATLEEQDDESDTADTDLM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00537661;
90% Identity: iTF_00507036;
80% Identity: -