Basic Information

Insect: Drosophila incognita
Gene Symbol: Kr
Assembly: GCA_035042225.1
Location: JAWNLQ010000240.1:3676984-3680020[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.00013 0.0087 16.5 3.7 1 23 274 296 274 296 0.99

2 5 3.5e-06 0.00023 21.5 7.8 1 23 302 324 302 324 0.98

3 5 4.8e-06 0.00031 21.1 3.7 1 23 330 352 330 352 0.98

4 5 2.2e-06 0.00014 22.1 0.3 1 23 358 380 358 380 0.98

5 5 0.011 0.7 10.5 7.4 1 20 386 405 386 407 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.00013	0.0087	16.5	3.7	1	23	274	296	274	296	0.99
2	5	3.5e-06	0.00023	21.5	7.8	1	23	302	324	302	324	0.98
3	5	4.8e-06	0.00031	21.1	3.7	1	23	330	352	330	352	0.98
4	5	2.2e-06	0.00014	22.1	0.3	1	23	358	380	358	380	0.98
5	5	0.011	0.7	10.5	7.4	1	20	386	405	386	407	0.94

Sequence Information

Coding Sequence: ATGGCCATATCAATGCTGCAGGACGCCCAAACACGAAGccttgctgctgcattggctGGCATAAAGCGCGAGGAAATGGTTGTGGATCGCTCGATGTCGCTGTCACCCCCCATGTCGGCAAACACGTCCGCCAGCAGCCCGGTGGCAGCCACGAATAGCCTCTACCCAGCGATGGGGCTGCaacaggcagctgctgcatctgcattCGGCATGTTGTCGCCAACACAACTCTTGGCTGCCAATCGTCAGGCGGCTGCGTTTATGGCACAGCTGCCAATGAGCACATTGGCCAACACGCTCTTTCCTCACAATCCAGCGGCACTTTTTGGCGCCTGggcggcacagcagcaacaacatcaacagcagcagcatcaattgcaacaacagcagttgcaacaacaacacttgccACTTGGCGGCACGCACTTGCACTCGCCGCCAGCGAGTCCTCATTCGCCGTTAGCCAACACTGGCAAACACAGCTTGAGCTCACCAAACAGCACTccacagcaccagcaacaacaaaatatggtTTTGGGTGAGCCTCTGAAGAAATCGCGGAAGCTCTCCGTCAAAAAGGAATTCCAAACGGAGATTAGCATGAGTGTCAGCGATCTATATAATCACCATCATAAttcgcatcatcatcatcatcatcatcatacgCCCAGTGGACCCATTTCCCCGCCCTCCAGCGGCAGCTCACCCAACTCCTCCGCACACGAGGCAagttcagcaacaacaacaacagttgcaacaacaacagcaacagttgcaacagctgctgctcccaCAAAGGATCCCTCGCGTGACAAGAGTTTCACCTGCAAGATTTGCTCGCGCAGCTTTGGCTACAAGCATGTCCTGCAGAATCACGAACGCACCCACACCGGTGAGAAACCCTTCGAGTGCCCCGAGTGCCACAAGCGCTTCACACGCGACCATCACCTGAAGACGCACATGCGTCTCCATACCGGGGAGAAGCCCTATCATTGCTCCCACTGCGATAGGCAGTTTGTCCAAGTGGCCAATCTCAGGCGTCATCTGCGGGTTCATACTGGGGAACGTCCTTACACCTGCGAGATTTGTGATGGCAAATTTAGTGATTCAAATCAATTGAAGTCGCACATGTTGGTGCACAATGGTGAGAAGCCGTTCGAATGCGATCGTTGCCACATGAAATTCCGTCGGCGACATCATCTGATGAATCATAAGTGTGGCATTCAATCCCCGCCACCAACACCCGCCCTCTCCCCGGCCATGAGTGGTGATTTCCCGCTtgcggctgtggcagctgcagctgctgcagcttcggCGCTGGAGAGTTCAACGCATAAGTTTGCCCAGATGTGCGCCAGTTATGGTGGCTCTGAGGAGTCCATGGAGTTGGGCAAGGATGCGGAAGATGCACCACTCGATCTCTCCGAGGACGGTGGCAGTTCTGTCGATGGCCAGTGTATTGGCAATGGCAGTGGTGGCAGTAATGCACGCCGCAAGGCTCAGGATATAAGGCGTGTCTTTCGGCTGCCACCGCCGCAGATTGCGCATGTGGCAAGTGCGATGCCGGAGCAAACGGAGCCGGAGGATTTGAGCATGCATTCGCCACGTTCGGTGGAATCGCATGAGCAAAACGAGGACATCGATCTCGATGAGCTCGACGATGCTGCGGCGCTTTATctgcgccagcagcagcagcagcagctccactaG
Protein Sequence: MAISMLQDAQTRSLAAALAGIKREEMVVDRSMSLSPPMSANTSASSPVAATNSLYPAMGLQQAAAASAFGMLSPTQLLAANRQAAAFMAQLPMSTLANTLFPHNPAALFGAWAAQQQQHQQQQHQLQQQQLQQQHLPLGGTHLHSPPASPHSPLANTGKHSLSSPNSTPQHQQQQNMVLGEPLKKSRKLSVKKEFQTEISMSVSDLYNHHHNSHHHHHHHHTPSGPISPPSSGSSPNSSAHEASSATTTTVATTTATVATAAAPTKDPSRDKSFTCKICSRSFGYKHVLQNHERTHTGEKPFECPECHKRFTRDHHLKTHMRLHTGEKPYHCSHCDRQFVQVANLRRHLRVHTGERPYTCEICDGKFSDSNQLKSHMLVHNGEKPFECDRCHMKFRRRHHLMNHKCGIQSPPPTPALSPAMSGDFPLAAVAAAAAAASALESSTHKFAQMCASYGGSEESMELGKDAEDAPLDLSEDGGSSVDGQCIGNGSGGSNARRKAQDIRRVFRLPPPQIAHVASAMPEQTEPEDLSMHSPRSVESHEQNEDIDLDELDDAAALYLRQQQQQQLH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00567799;
90% Identity: iTF_00544043;
80% Identity: -