Basic Information

Insect: Drosophila incognita
Gene Symbol: Hivep2
Assembly: GCA_035042225.1
Location: JAWNLQ010000074.1:1025117-1033224[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0017 0.11 13.1 0.4 2 23 268 289 268 289 0.98

2 8 0.00026 0.017 15.6 3.2 1 21 295 315 295 319 0.90

3 8 0.011 0.73 10.5 0.2 1 19 962 980 962 983 0.93

4 8 3.1e-06 0.0002 21.7 2.0 1 23 1729 1751 1729 1751 0.99

5 8 1.3e-05 0.00086 19.7 5.3 1 23 1757 1781 1757 1781 0.92

6 8 0.00059 0.039 14.5 3.5 2 23 2263 2284 2263 2284 0.97

7 8 0.00089 0.059 13.9 1.2 1 23 2290 2314 2290 2314 0.91

8 8 0.0029 0.19 12.3 2.7 1 23 2335 2359 2335 2359 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0017	0.11	13.1	0.4	2	23	268	289	268	289	0.98
2	8	0.00026	0.017	15.6	3.2	1	21	295	315	295	319	0.90
3	8	0.011	0.73	10.5	0.2	1	19	962	980	962	983	0.93
4	8	3.1e-06	0.0002	21.7	2.0	1	23	1729	1751	1729	1751	0.99
5	8	1.3e-05	0.00086	19.7	5.3	1	23	1757	1781	1757	1781	0.92
6	8	0.00059	0.039	14.5	3.5	2	23	2263	2284	2263	2284	0.97
7	8	0.00089	0.059	13.9	1.2	1	23	2290	2314	2290	2314	0.91
8	8	0.0029	0.19	12.3	2.7	1	23	2335	2359	2335	2359	0.92

Sequence Information

Coding Sequence: ATGACGCTACAGCAGGTGGCAAGCAGCGCAACGAGCaaggtggcaacaacaacaacaataataccagccacagccaacaccacaagcaacaacaaccagaacaacaacaacaacaacaacagcaccagcaacaaccacaatgtgctggccaacaacaacagcagcagcgatgatccaacaacagcggcagcaataaATGTCGACGGCTGGACGAGCTCATCCACTTTGcgttatttgcacaaaaagtTTAAGCGGCTGGCGAGCACCACCGAACCGGAGTCGGTCGATACAATGGCGGCGGCGCGCACCACATCGCTGTCATCGAATAGCTCGTTGTCGCCACCGCTGCCAGTTGCGGCTGCTCCTCTGCTCAATGGACATGTGACGGTGAAGGTTGCTCCCTTGCTGCCGGCAAGAAATTTAGAATTCAGTGCCAATTTCGTAAATgccaacgacaacatcaacaacaataacaacggtCATGATGAGAGCAAGCATGGCaatgttggtgttgctggtgcgCCTCGAACACGCACGCCGCTCAGCAACAGtaattgcaacagcaatattAACTATGCCAGCAATGCAACACTGTCGCCAGCAACATTcgcacagcatcagcaacaaacgcagccaacgccagcagcaacagcagccgtcgTTGCAacattagcagcaacaacaacaacaacaacagcagcagcaacaacaaccacaacagcagcagcagcagcaacaacagcaacaataatacaaacagcagcagtaacagttGCAGGATTAGAGAAAACTAGTCGCCCCAAGTGCCCCTATTGCAATCTGATCTGTGCAAAGCCGTCGGTGCTGGAGAAGCACATTCGTGCCCACACCAATGAGCGACCGTATCCGTGCAACAACTGCGGCATCGCCTTCAAAACGAAGAGCAACCTGTACAAACACTGCCGCTCCCGTTCCCATTTGGCGCGCATGCGCGGCCTCGATGTACCGGCCAATGAGACGGACGGACTGTCCGACCAGGATGGCGATGGGGagctgagcaacagcagctccgAGCTGCTAAGCGTTGAAATTTTGAGTCGCACAGATTCGCCTTATGATGAGGCCATGGCCTCGCCCacgccatcgccatcgacGCTGTCGGCGGCAAAGAGTACGTATCTGCAACAGccgcaattgcaacagcataTGCTACAACAGTTGCCGCTGGGCTCGCCTGCCGCCGGAACACTGCCGCCCGCCCCGCCCGCTGACTCGCTGCACTCGGCAACCGCTCAGCATCGCCAGTCGCTCGACTACAAGCCATACAAGCCCAAGTTTCACAATGCAGCCCTTTATGCGCCCGGCACGctcaaggagcagcagcagcagcaggtactgcaacagcagcagacgctgctgcaaccacaacagcagccacataaACTgtcagcgcagcagcagcagcagcagcaaccatcGTTGGCGCATCCAACGCTCTCGCCCAGCACCCAGTTGAAGCTTAACAATCACATAAACTCGcatcagctgcaattgcagctacagcatcagcaccaacagcagcaacagcatctgcACGCCCAGCAATccctgctgctggcagcggcagcaaccaATCCGGTTGCATTGTCAGCCttaccaccgccgccgccgggCGTTTATTATTTGGGACAGCCGCAGTATTATAatccaactgcagctgcaatgcATCAGCATGCGCTGGCCATTCAgcagatgcagttgcagcagcactttcagctgcaacaacagcagcaacagcatcaccaacagcagcaacagcatcagcaacaccagcagcagcagcagcagcaacaacaacagcagcagcagcagcaacaacaacagcagcagcaacaacagcagcagcagcaacattcgCCGCTGCTGAAGGcgacacagcagcaacagcagcagCTGTTGCGCTCAAATAGCCAACAACAGGCGGCAGtcattgcaacaacagcatcgcTGCCCGCACCTGCTACACCCAACCCGCCTACCAATCTAAGCAGCTTTGCCAGCTCAAGCGGCGGCATGCAAGTGAATGTGGAAAAAGTGCAGGAGCACATCTCTAAGCTGATCTCACAGAACGAGGCCATTGTCGAGAACAAGGAGATACTGCTGCAGAAGAAGTATCCCAAGCAGCTGAATCGTTCGCGCAGCttcaacaatgccaacaacaataatagcagcaatggcagcaacatcaacagcagcagtataCCAACAACAGCgcaagccaacagcaacagcagcaacaacaacagcaatcaacaGCTGGGCGAGACTAAAGTGAACCTGGCACAGGCGATAgtacaaaaacagcagcagcaacagcatatgcaacaacagctgcagcagcaacaataccaattatatttgcagcagcagcaacagcaactggagcCCCCGGTTAATGGTCTGCtgaagcgcagcagcagcagctctgcGTGCAGCTCAGCCAGCAGCGGCTATGTCAGCCTTAAGGGCACAGCAACCCCAACACCCGCCGCACCCACGGCAAGTGTgaaacagttgcaacagttgccgccgccgccatcgCCGTTGCCATTGCAACAGTTACAGTACCGCCAGGATCCGTCAACGCCAGTGCCtaagctggagcagcagctgcagttgcagcaacccTTGGCACCCAATCATGCCCAGCCTTTGAATTTGTCTGCCAAGCCCAAGCCACTAGCAATGCCatcaaaaccaacagcaacagcagccgcagcaacaactgttggcaagatgacaacagcagcgcagGCGGCTACACCGAATATATCCATAATCAAGAATCTGCTGTTGAATGCACGTGGCTTGGCAGTGCCAATTGGCGAGGGCGATGATGCCGTCTACTCCTGCCCCATTTGCGCCAACGAGTTTCGCAGCGCGGATGAGCTGAAGCACCACAACAGCACCTACTGTCAGGATGCGAACAGCAGTGCTCCCATCAGTCCCGCCTCATCCCCGAGCAGCAAATACTTTCGCTCCAATTCCATATCGTTTAGTCTGCCGGAGCTGCAGTCGCACATGGCCAACTCGAAGAATCCGTTGTCGCTCGCCAAGCTTGCCAAGGTCGCCTGGTCGCAGCTAAAAACCAAGCCAAGCAGCCTGGTTCTCAGTCGTCTCAGTGCGGCTCAATCTCCCGCACGCACCTCAACCGTCACAGCAGCCaccaacagcatcagcaacaacataaacagcatcagcagcaacatcatcaatcacaacagcagcagtaatcaCATAagaacagcagcggcagcaactgttgtAATCCCGCCCAGCATTGATGCTTCCGGCGTTGCTTTGCGTTTTGTGGACGCACCGCTGCCATCGCCGGGTCCACTGCTCGGCAAGACACCGCTGGTCGATTATGCGGCGCCGCGCAAGGCTCCCGATGCCCAGGTGGTCATCACGAAAATGCACGAGGATCGCTTGGAGAACATCATCGTTGAGGCGCCATCGAAACGGCTCAAACTGAGCAGTGGCGAGACAGCGTTCACTCTTTTTGCTGGCAATCCGGATTTGCAGTTCAGTGCCAAGGAGGAGCGTCTGCGTCGCTTTACCTCATCCGGCGGCACGATGATACCCATTTCTGAGTGTCCCGAGCTGAACGAGAGTCCCAAAATGATACGCACTCCGCTGTTGTCCGGCGGCAGTTTCCAGGAGATGTCGCCCCGTCTCAGCGACGTCAAGGAGCGCAAACTTCtcgctgccaacaacaacaacaacaacaacaataacaataataataataatggtttTCTGCTGAGCGCCTCAAACACGCCgcatcattttcaatttcccaTCAATTCGATAACGGCCTTCAATCCGCTCACGCTGCCACccatgagcaacagcagcggcagcagcagcagcattaacaCCAGCAATCTTGTTGATAAGGCAATACCCTATGTGCCGGGCATACCCGGTCCGGGCAGCTTATCGTTGCTGCCACCgccactgcagctgcagcgtgGACGCAGTCCCAATCGCAAACAGCCCAGTCCCAATTCGAATTCCAATCTCAATCTTAATCTCAATCCGCTGCTGGCAGCCGAGGGCCCGCTGAAGGCACTCTCGCCCTTCGGTGGCGTTCAGAACTTGCCCAGCGAATTCAGTCGACAGCCACCAACGCCAGCGCAGCGCAATGCGCTCCAAtggaccaacaacaacaacagcagcagcagcaataagtTGCCAGTGATTGTGGCTGACAAGAAGCCACCGTTCAATTTTCTACGCATGGCGGATAATGTGAAGAACTCCACTATGCAGGAGCAACAGCCCCCGTCTCAATCTCAATCCCAGGCAATGGGTATGCCAGAGGTGCGTCACTTTAATTTCGATAATGTGAACAAATCGCAGGAGGCGCTGGCGCCGCTGCATGTGGACACACCCGACGAGGCGATTGCAACAGCAGTAGGAGCAATcaaaacatcaacagcagcaacttctattctggcagcagcagcaacaaccacaacgagcAGTGCCAAGTCTAAGTTCTTGCGACCCACCAGTCTGCCTCTGAAGCCGGGCACCTTTACGCCGAAGCGACATCATGGCATCACACCCACTGCGAATACACTGCCCCTAATCTCACCGGAAACGCCAAGACCCTCTAAGTCGTGCGTGCAACTGTATCTGAATGGTCACGCGTATACCTATCTGGGGCTCAAGTCCAGCACAAAGATGTTCTACTGTACGGTGAACTGTCCGCAGCCCTCGTATGTCGCTGGCATGCACAAACTGTCGATGTACAGCGTGTGGCAGGTATGCGAGGAGAATCAGCCGCATCCGCTCGGCTTCAAGCCCAAACAGGTGATGGCTCTATACGATTCCCGGCAGAAGATGCTCGGCACTGGCTGCACCACAGCGATGGCGGGTGCCGGCAAACTGCAGTACTCCGTCTTCTGTTCACAGGAAACGGTTAGCACGAGCTCCACCACGGCCAACGGGCAGAGCAAGTTCTACCAGCACCAGCTGAAGCAGCCGCCGGCAATTGGCGCGCTCAGCGAGGCGAATGTGGCCGCCAAGGCCAGCGAGGAGGCGGCTGCCAAGAAGCTGGAGTCGAGCCAACTATTGGTCGGCGGTTACGAGTCGCATGAGGATTACACGTATATTCGCGGACGAGGGCGTGGTCGCTACGTCTGCTCCGAGTGTGGCATACGATGCAAGAAGCCCTCCATGCTCAAGAAGCACATACGCACCCACACGGATGTGCGTCCCTTCACCTGCAGTCACTGCAACTTCAGCTTCAAGACCAAGGGCAATCTTACCAAGCACATGCAGTCGAAGACGCACTTCAAGAAATGCATCGAGCTGGGCATCAATCCGGGTCCGATGCCCGCCGACGGCGAATTCCTTGATGTCGATGTGGACTTTGATCAGCAATCCTCGACATCAGCAGGCGGACGCACCTCCTCCATGGCCGGTGAATCCGATTCGGATGACTACAGCGACAACGAGTCCGAAAGCAGTGACACCGATGAGTCCAAGTCGCGCATGAAGGAGCACGAGGCTGCTCGTGgtctgctgtcgctgtcgatGACGCCGCCGATACCGCAGAGTGTTTCACCGTATCCGGCACTGGTGCAGGACACGCCGGCTGCCAGTCCAGCGAACAGCATTGGCTCGTCGGCGGGCAGCGCAGCTGGCGGCTCGCAGCCGAAGCGTCAGGTGTGCTCGTTTACGTCGCCAAAGCCGCCGTTTGACTaccagaagcaggagcagtaTTACTCTAATCCCGAGGAGTCTAAACCTAAGCGCGGTGTGCCTAACGACGAGAGCAGTGCACCCATGGATCTGACCAAGCCACGCCCAATGCCCAGCATTTCAGTTGCCGCCTCTTCGCCCGTGCCggagcagctgcagatgcAGACGCCCAAATCGCAGGCACAGCAGATGCGCGACGTCATCTTTGGTGCGGGCAACAACGAGTGCGGCTTCATGAAGACCCTAATCTCTGTCTCCGATAAGGTGCGCATCTCTGCCGAAATTGAGGAGCAGGCGAAGCGCGAAAGCGAAGGCGAGGATGTCCTCCTGCAGACCTACATCAAGGAGCAGGCGCTGCAGCATGCCAAAATGAAGCAGAGCCAATTTAGCCGCAGCTACCTGGTGACCTCCACCACCAACTCCAATTCCAACTGCATCTCCGCAAGCTCTAGCTGCAGCTCCATCTCTACCACGAGCAGCATtagctgcatcagcagcagctatgTTGTGGCCACGCCCCTTGTTAATAGCAAACCACAGTTGAACATCGCGGAGCTGCCCAGCATTGAGGTGCACGAGGTGAGGACACCAGAGTCGCCAACGCCATCGCCGGCTGTTGGGCATGCTGCCATCAAATCCGCCGAGGAGAGTGAAGAAAGCGAAACGCAATCGGATCAGGAGAAGCCAACCATAAAGTCCATTCCTGTAACTGTAACAGTACCTGCTTCAGTCACTGTGCCCGTTTCCAGCGTGGAGATTCAGCAGCCGCACAATGCCAATTTGCctgctgcagtgcagcagccAGATGCCACCGATTTTAGCGGCgtactcagcagcagcagcaacaaaaatagcagcagcagtggagcAACTGCACCCACACGTATTGTGGTCGCCGGAGAGGATGGCTTCAAGACAACTCCAACCAGTGCCAGCAACGAATTGCAGTCTGGAGGAGCACCCGCTGGAGCAACTTATACGAATCGTGTggtgccaccgccaccgccgccaatTGCGAGTGATGCGCGACCCACTTGCACCGTTTGCAACAAGACGTTCCAGCGAACGCATCAGCTGTCGCTGCACATGAACATCCACTACATGGAACGCAAGTTCAAGTGCGAGCCGTGCAGCATCTCGTTCCGTACACAGGGTCATCTGCAGAAGCACGAGCGGAGCGAGGCGCACAGGAACAAGGTGATGATGACGTCGACATTTGGAGTGCCCACCACATCCAATCCGCGTCCGTTTGAGTGCACCGATTGCAAGATTGCGTTTCGCATCCACGGCCATCTGGCCAAGCATCTGCGCTCCAAGACGCATGTCCAGAAGCTGGAGTGCCTGCAGAAGCTGCCATTTGGCACCTACGCTGAGATCGAACGTGCTGGCATCAGTCTGACGGAGATCGACACCAGCGATTGTGAGAATTCGCTCATCTCGCTCAAGCTGCTGGCGCAAAAGCTGCTCGAGAAGGATCCAAACAAGCTGAGTGGCTACACAACGCCGTCGGGCATGCTGCAGCTGTCGGCAGATGCACCTGCTGCCGGCCAGGACAGTGCCTCCGAGGATGGCTTCAGTGCGGCGAACAGTGCCGCCGCCTCGGCCATTGCCTCGCTGGACAACGACAGTGCGGGCAACACACCCAAGCGGGCCAGCTCCATGTCCGAGGATGAGACGCTGACCAACGGACTCGGACTCAGTCACAGCCATGGCCACAGTCTGAAGCGGCGTCTGCAGCacagcagcttcagcagcaaTGGCGATGAGAGCGACAACCCAACAGATGCCACGGCAGCGGGCACTGGCTCTGgcactggcagtggcagtgtcAGCAACGAGAAGCGTGCGAGAAGCAACACAAATGAGATCACACTGCCGACCCCGGTGGCTGTGTCAACGGCAACAGCCAGCAACTGa
Protein Sequence: MTLQQVASSATSKVATTTTIIPATANTTSNNNQNNNNNNNSTSNNHNVLANNNSSSDDPTTAAAINVDGWTSSSTLRYLHKKFKRLASTTEPESVDTMAAARTTSLSSNSSLSPPLPVAAAPLLNGHVTVKVAPLLPARNLEFSANFVNANDNINNNNNGHDESKHGNVGVAGAPRTRTPLSNSNCNSNINYASNATLSPATFAQHQQQTQPTPAATAAVVATLAATTTTTTAAATTTTTAAAAATTATIIQTAAVTVAGLEKTSRPKCPYCNLICAKPSVLEKHIRAHTNERPYPCNNCGIAFKTKSNLYKHCRSRSHLARMRGLDVPANETDGLSDQDGDGELSNSSSELLSVEILSRTDSPYDEAMASPTPSPSTLSAAKSTYLQQPQLQQHMLQQLPLGSPAAGTLPPAPPADSLHSATAQHRQSLDYKPYKPKFHNAALYAPGTLKEQQQQQVLQQQQTLLQPQQQPHKLSAQQQQQQQPSLAHPTLSPSTQLKLNNHINSHQLQLQLQHQHQQQQQHLHAQQSLLLAAAATNPVALSALPPPPPGVYYLGQPQYYNPTAAAMHQHALAIQQMQLQQHFQLQQQQQQHHQQQQQHQQHQQQQQQQQQQQQQQQQQQQQQQQQQQQHSPLLKATQQQQQQLLRSNSQQQAAVIATTASLPAPATPNPPTNLSSFASSSGGMQVNVEKVQEHISKLISQNEAIVENKEILLQKKYPKQLNRSRSFNNANNNNSSNGSNINSSSIPTTAQANSNSSNNNSNQQLGETKVNLAQAIVQKQQQQQHMQQQLQQQQYQLYLQQQQQQLEPPVNGLLKRSSSSSACSSASSGYVSLKGTATPTPAAPTASVKQLQQLPPPPSPLPLQQLQYRQDPSTPVPKLEQQLQLQQPLAPNHAQPLNLSAKPKPLAMPSKPTATAAAATTVGKMTTAAQAATPNISIIKNLLLNARGLAVPIGEGDDAVYSCPICANEFRSADELKHHNSTYCQDANSSAPISPASSPSSKYFRSNSISFSLPELQSHMANSKNPLSLAKLAKVAWSQLKTKPSSLVLSRLSAAQSPARTSTVTAATNSISNNINSISSNIINHNSSSNHIRTAAAATVVIPPSIDASGVALRFVDAPLPSPGPLLGKTPLVDYAAPRKAPDAQVVITKMHEDRLENIIVEAPSKRLKLSSGETAFTLFAGNPDLQFSAKEERLRRFTSSGGTMIPISECPELNESPKMIRTPLLSGGSFQEMSPRLSDVKERKLLAANNNNNNNNNNNNNNGFLLSASNTPHHFQFPINSITAFNPLTLPPMSNSSGSSSSINTSNLVDKAIPYVPGIPGPGSLSLLPPPLQLQRGRSPNRKQPSPNSNSNLNLNLNPLLAAEGPLKALSPFGGVQNLPSEFSRQPPTPAQRNALQWTNNNNSSSSNKLPVIVADKKPPFNFLRMADNVKNSTMQEQQPPSQSQSQAMGMPEVRHFNFDNVNKSQEALAPLHVDTPDEAIATAVGAIKTSTAATSILAAAATTTTSSAKSKFLRPTSLPLKPGTFTPKRHHGITPTANTLPLISPETPRPSKSCVQLYLNGHAYTYLGLKSSTKMFYCTVNCPQPSYVAGMHKLSMYSVWQVCEENQPHPLGFKPKQVMALYDSRQKMLGTGCTTAMAGAGKLQYSVFCSQETVSTSSTTANGQSKFYQHQLKQPPAIGALSEANVAAKASEEAAAKKLESSQLLVGGYESHEDYTYIRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPFTCSHCNFSFKTKGNLTKHMQSKTHFKKCIELGINPGPMPADGEFLDVDVDFDQQSSTSAGGRTSSMAGESDSDDYSDNESESSDTDESKSRMKEHEAARGLLSLSMTPPIPQSVSPYPALVQDTPAASPANSIGSSAGSAAGGSQPKRQVCSFTSPKPPFDYQKQEQYYSNPEESKPKRGVPNDESSAPMDLTKPRPMPSISVAASSPVPEQLQMQTPKSQAQQMRDVIFGAGNNECGFMKTLISVSDKVRISAEIEEQAKRESEGEDVLLQTYIKEQALQHAKMKQSQFSRSYLVTSTTNSNSNCISASSSCSSISTTSSISCISSSYVVATPLVNSKPQLNIAELPSIEVHEVRTPESPTPSPAVGHAAIKSAEESEESETQSDQEKPTIKSIPVTVTVPASVTVPVSSVEIQQPHNANLPAAVQQPDATDFSGVLSSSSNKNSSSSGATAPTRIVVAGEDGFKTTPTSASNELQSGGAPAGATYTNRVVPPPPPPIASDARPTCTVCNKTFQRTHQLSLHMNIHYMERKFKCEPCSISFRTQGHLQKHERSEAHRNKVMMTSTFGVPTTSNPRPFECTDCKIAFRIHGHLAKHLRSKTHVQKLECLQKLPFGTYAEIERAGISLTEIDTSDCENSLISLKLLAQKLLEKDPNKLSGYTTPSGMLQLSADAPAAGQDSASEDGFSAANSAAASAIASLDNDSAGNTPKRASSMSEDETLTNGLGLSHSHGHSLKRRLQHSSFSSNGDESDNPTDATAAGTGSGTGSGSVSNEKRARSNTNEITLPTPVAVSTATASN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00513682;
90% Identity: iTF_00482470;
80% Identity: -