Basic Information

Insect: Drosophila immigrans
Gene Symbol: ush
Assembly: GCA_963583835.1
Location: OY757143.1:38695357-38714070[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0072 0.48 11.0 0.0 1 20 232 251 232 253 0.90

2 9 0.00031 0.02 15.3 0.8 1 23 303 325 303 325 0.98

3 9 0.055 3.7 8.2 1.0 2 21 381 400 381 401 0.92

4 9 0.054 3.5 8.2 2.9 2 21 794 813 793 814 0.93

5 9 0.01 0.66 10.5 0.0 3 21 864 882 862 883 0.91

6 9 0.0072 0.47 11.0 0.0 2 23 947 968 946 968 0.98

7 9 0.0042 0.28 11.7 1.3 1 23 974 996 974 996 0.99

8 9 0.00072 0.047 14.1 0.7 1 23 1067 1090 1067 1090 0.96

9 9 0.45 30 5.3 0.5 2 20 1202 1220 1201 1222 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0072	0.48	11.0	0.0	1	20	232	251	232	253	0.90
2	9	0.00031	0.02	15.3	0.8	1	23	303	325	303	325	0.98
3	9	0.055	3.7	8.2	1.0	2	21	381	400	381	401	0.92
4	9	0.054	3.5	8.2	2.9	2	21	794	813	793	814	0.93
5	9	0.01	0.66	10.5	0.0	3	21	864	882	862	883	0.91
6	9	0.0072	0.47	11.0	0.0	2	23	947	968	946	968	0.98
7	9	0.0042	0.28	11.7	1.3	1	23	974	996	974	996	0.99
8	9	0.00072	0.047	14.1	0.7	1	23	1067	1090	1067	1090	0.96
9	9	0.45	30	5.3	0.5	2	20	1202	1220	1201	1222	0.91

Sequence Information

Coding Sequence: ATGATCAGCACTCAaccagcaacggcagcaacaacagcgacaaccacaacaaaagGAGATTGTTCCGATACCACTGAAGAGATGACCGTCGACAGCAGAGATTCCAAAGATTTAGGTGCACGCGAGCTGAGCGAGgagaaggagcagcagcaagagtTCGAGGAGCTGCCCGAgccggaggaggaggcggagcaGCCAAGAAGCGAGGAGAACCACACGAGCAACCACAGCTCCGACCAGCCCATGGAGACAGACATgcacatggacatggacatggccatggacatggacatggggGAGGTACAAGAGGCAGCCGAGCAGGCGgtcgagcagcggcagcagcagcagaaggaggTTGACGGCAACTCGACGACGCCGCCGCGCAGCCCGACGACGCCCGAGCTGGTGCCGAAGCTGGAGCGCATGGAGCAGCCAGCCACTCCGCCCTCGGCGGCCGCCACGCCCAGTCCCCCGCCCACGCCCACTCCCACGCCCACAATCGCAGCGCTGCCCAAGCTGAGGCTGAATGCGTTGCTCGCCTCGGATCCGGCGCTCAAGCCGGACGCCAAGGAGCTGAACCTGAGCGACGCGCGTCTGCTCGCTCCGCCGCCGCAGCTGCCAAAGCCAGAGCCGCCCCAGAGTCTGGCCGACGGCAGCCTGGGGGGAGAGCCAGCGCTGATGAAGCCGACGCGCTTCATGTGCCTGCCCTGCGGCATCGCGTTCAGCTCGCCGTCGACGCTGGAGGCGCACCAGGCCTACTACTGCTCGCACCGCAACAAGGAGGCGGACGAGGAGGGCGGCGCGGGCGACAAGCAGCCAGGAGCGGCTGGAGGAGCTGCTGCcgccagcggcagcaacaacggcagctcGGAGCCGCCGGCGAAGTTGGCGCGCACCGGCAAGCAATACGCGTGCACTCAGTGCTCCTACAGCGCCGACAAGAAGGTCTCCCTCAACCGGCACATGCGCATGCACCAGACCTCGCCCGCCCCCAGCCTGCCCAGCCTCGCCAGCCTCACCGCCAACGGCGTGTCATCTGTGGGCGGACTTGGAGTCGGActcggagttggagttggagctggcGGCGGGGGAGTTGCGGGAGCGGCGCTCGAGGAGAGCTCTAGTCAACAAATCGATCGCTACTGCAGCGACTGTGATATCCGCTTCAACAACATCAAGACCTACCGCGCCCACAAGCAGCACTACTGCAGCTCGCGCCGCAGCGACGGCCAGCTGACGCCCAAGCCCGAGGCGGGCGTCCCCCCCTCCTCGGGCCCAGCCACGCCCGTCGCCTCCGCCGGCAAGCTGAGCGGCGCCCACAGCCCCCAGACGCGCAACAAGACGCCCACTCCAGCCAtggttgctgccgctgccgccgccgccgcagccgctgctgccgcctcgCTGCAGGTGACGCCGCCGCAGCCCTTCCTGGCACTGCCCACCAACCCGATCATCATCGTGCCCTGCTCCCTGATCCGCGCAGCCAGCCTCATCCCGGGACCGCTTACCACGTCGACTTCGGGCATCGTTAACCCGGAGTCCACTTGCTTCACCCTCGACAACGGCGCCTTGAAGCCGCTGGCCACAGCCTTGAACATCAATGCGCTGGCCGGGAGCGTGACGCCGACGCCGCCAATGCCCGGCAGCAATCAGCAGCAGAGCGTCGCTGCTCTGGAGCCGGAGCGTCCGTCAGTGGGCAACAGCGAAGCGGAGACGAAGAGCAGTCCGGCTGAGCCCAAGCGCAAGGAGgcgggaggaggaggaggaagcggaggcggaggcacTCGCGAGTCCACTCCGCTGGATCTCTCGCTGCGTCGCTCGCCCATCGCggcgctgctgcagcgccAGCGGCTCGTGCGCTCCGCGGCCGCGCTGCTCGAGGCGGAGGAGGCGCTGCTGGCGACGGCGGGCAAGGAGAACCTGGAGGGCGGCAGCGTCACCCCGGAGCAGATCGTGTGCGCGCCCTCGCTGCCCAGCAGCCCCTCGATGAGCCCCTCGCCCAAACGACGCGCCGTCAGTCCGCGCAGCTCTGGCGCCGGCAGCGCCGCCTCCATGTCGCCCCCCACGCTGGGCGTGGGCGTGCCCCATCTGCTGGACAACCTGCCGCCGCTGCGCTCCATGCTGCCCGCGGACTTTGCGCTCTCCGCCGAGTCGCTGCTGGCCAAGACCAACCCCGAGCTGGCGCTCAAGCTGgcagccgccgcagcagcagccgttgcCGGTAGCAGCTCGGCCGAGCTGGCCAGCAAGCTGGGCTTCCCGACAGCCCCAGGCGCAGGatcaggagcaggagcaggcaACGCATCAGCTGCCACATCAGCTGCCAACACGCCTAGTGGACAGCCGCAGATCTACGTGAAGCAGGGCGTGTCCAAGTGCAAGGAGTGCAACATCGTGTTCTGCAAGTACGAGAACTACCTGGCCCACAAGCAGCACTACTGCTCCGCGCGCAACCAGGAGACGGGCGAGGGCGAGGCCAAGGGCGCCAGCTCGCCGCCGGGAGGCGCCGCAGCAGCCGCTGGCACAGCTGGCGGAGCGGGCAACGCGGCGGAGACGACGCCCGTGGCCTACCAGCAGCTGATCTGCGCCGCCTGCGGCATCAAGTACACCTCGCTGGACAACCTGCGAGCCCACCAGAACTACTACTGCCCCAAGGGCGGCGCGGCGGCCACGCCCGCTGCGGAGCCCGTGCagacgcagctgcagctggccaaGGAGAAGTGCGGCAAGTGCAAGACGCTGCACGAGCACGCTCAGCCCTGCCCCCCGCCTCCAGCGGCGCCTCAGCTGCCGCAGCTCAGTGCTGCCGTGTCCTCCTCGAACAGCGTCAACAAGTGCCCCGTCTGCGGCGTGGTGAGCCCCACGGCGGCGCTGGCCCGCAAGCACATGGAGATGCACGGCACCGTGAAGGCGTTCCGCTGCAGCATCTGCCAGTACAAGGGCAACACGCTGCGCGGCATGCGCACCCACATCCGCACCCACTTCGACAAGAAGACCAGCGACGTCAACGAGGAGCACTACATGACCTGCATCTTCGAGGAGGACGCCGCTGCCGtggccgcagccgcagcagccgcagtcgcagccgctgctgttgctgttgcggcgcCCGCTCTGGGGATGGACGTGGCCGCCGTGGCCACGCCGCaggagcagctggagcagcagcagtcgcagcaTCCGCCGCAGATCTTCAACTGCGACTACTGCAACTATGCGTCCAGCTACAAGGGGAATGTGCTGCGCCACATGAAGCTGCTGCATCCGCACGTGGCCATCAGCTCGCCCTCCATCTCGCCAGAGACGCGCGAGCAGGAGCTGAATCCGCACGCCGAAGTGGCGCTCGTCAACGGCGATCGCGACAGCTCCTCAGTGGCCAGCTTCCACATCAAGTCGGAGCCGCTGGAGCAACAGCCCGTGGCGGCCACGCTGAGTCTGGTGCACGAGAACAACAACTCGCCCATCGGCACGCCTCACACCCACATCAAGGCCGAGCCCCTGGACATGGGCATGGAGGTGTCGCCGCCCTCGCTGCCCCCGCCGCCCGTGTCCAACTCGCCGCTGGGGCCCAGCGCGGCCGCCGAGGCCATGAAGAAGTACTGCTCCACCTGCGACATATCCTTCAACTATGTCAAGACCTATCTGGCCCACAAGCAGTTCTACTGCAAGAGCAAGCTGCACCGACCCGAGGCCAACGACAGCCCCAGTCCCAACCACATGAACCACCTGGGCGCCGCCGTGCCGCTGCAGTCGCCCagcgagctgctgctgctccagaaGAACAAGGAGAATCTGCAGGAGGCGGCCATTTGA
Protein Sequence: MISTQPATAATTATTTTKGDCSDTTEEMTVDSRDSKDLGARELSEEKEQQQEFEELPEPEEEAEQPRSEENHTSNHSSDQPMETDMHMDMDMAMDMDMGEVQEAAEQAVEQRQQQQKEVDGNSTTPPRSPTTPELVPKLERMEQPATPPSAAATPSPPPTPTPTPTIAALPKLRLNALLASDPALKPDAKELNLSDARLLAPPPQLPKPEPPQSLADGSLGGEPALMKPTRFMCLPCGIAFSSPSTLEAHQAYYCSHRNKEADEEGGAGDKQPGAAGGAAAASGSNNGSSEPPAKLARTGKQYACTQCSYSADKKVSLNRHMRMHQTSPAPSLPSLASLTANGVSSVGGLGVGLGVGVGAGGGGVAGAALEESSSQQIDRYCSDCDIRFNNIKTYRAHKQHYCSSRRSDGQLTPKPEAGVPPSSGPATPVASAGKLSGAHSPQTRNKTPTPAMVAAAAAAAAAAAAASLQVTPPQPFLALPTNPIIIVPCSLIRAASLIPGPLTTSTSGIVNPESTCFTLDNGALKPLATALNINALAGSVTPTPPMPGSNQQQSVAALEPERPSVGNSEAETKSSPAEPKRKEAGGGGGSGGGGTRESTPLDLSLRRSPIAALLQRQRLVRSAAALLEAEEALLATAGKENLEGGSVTPEQIVCAPSLPSSPSMSPSPKRRAVSPRSSGAGSAASMSPPTLGVGVPHLLDNLPPLRSMLPADFALSAESLLAKTNPELALKLAAAAAAAVAGSSSAELASKLGFPTAPGAGSGAGAGNASAATSAANTPSGQPQIYVKQGVSKCKECNIVFCKYENYLAHKQHYCSARNQETGEGEAKGASSPPGGAAAAAGTAGGAGNAAETTPVAYQQLICAACGIKYTSLDNLRAHQNYYCPKGGAAATPAAEPVQTQLQLAKEKCGKCKTLHEHAQPCPPPPAAPQLPQLSAAVSSSNSVNKCPVCGVVSPTAALARKHMEMHGTVKAFRCSICQYKGNTLRGMRTHIRTHFDKKTSDVNEEHYMTCIFEEDAAAVAAAAAAAVAAAAVAVAAPALGMDVAAVATPQEQLEQQQSQHPPQIFNCDYCNYASSYKGNVLRHMKLLHPHVAISSPSISPETREQELNPHAEVALVNGDRDSSSVASFHIKSEPLEQQPVAATLSLVHENNNSPIGTPHTHIKAEPLDMGMEVSPPSLPPPPVSNSPLGPSAAAEAMKKYCSTCDISFNYVKTYLAHKQFYCKSKLHRPEANDSPSPNHMNHLGAAVPLQSPSELLLLQKNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00509368;
90% Identity: iTF_00614454; iTF_00509368;
80% Identity: -