Dimm008459.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila immigrans
Gene Symbol
-
Assembly
GCA_963583835.1
Location
OY757142.1:23624348-23630532[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 0.0019 0.13 12.8 3.0 1 23 970 992 970 993 0.95
2 8 0.18 12 6.6 1.0 1 23 998 1021 998 1021 0.96
3 8 8.8e-05 0.0058 17.0 0.8 1 23 1213 1236 1213 1236 0.96
4 8 0.0024 0.16 12.5 0.8 2 23 1245 1266 1244 1266 0.97
5 8 0.039 2.5 8.7 0.3 1 23 1273 1296 1273 1296 0.96
6 8 1.5e-05 0.001 19.4 1.4 1 23 1302 1324 1302 1324 0.97
7 8 8.1e-07 5.3e-05 23.4 2.2 1 23 1329 1351 1329 1351 0.99
8 8 0.0008 0.052 14.0 4.4 1 23 1357 1379 1357 1379 0.99

Sequence Information

Coding Sequence
ATGGTGGCTAAGTTCCGACGGCGATGTGTTCGCGTGCAGCAGCGACTTCAGGAGTACGCCCAGCAGATTGCCCAACGCCAAGAACGACGCCAGccaccacaacagcaacagctcgaCAAGGAAACAAATAAGCAAGCAATATCCAATCTGCCTGAATCACAACCGGAGCGCAAGCGTCGCCTGGAGGAGTCGCCAACAGTTCAGAGCGAAGCATCATCGCCCAAGCTCAAACGACGCAATGCATCCCACCTTGCAACTACAATGACGACTAGAAACTCCAAGTCGAGATCGCCCTGCAAGAGAATCAACAAGCCCTGGCGAACGAAGGCGGCGCGAAAGCAACTGTCAGAAACGTGGTCCACAAGCTCCTCGTCGTGTCTGACCACAGAGCGctctacagcaacaacagcaccagTTTCCAATTGCCCTTCGTCCACATCTTCATCGTCGGGTCAGACAACACCGGAGCACCTCAGCGATTTGTCTGTAAATCCGTGTCGTGGCTTCCCCAGCGATGGCAATTCCTCGACCTCATTGACCAACTCCGACGGTCAAACGACGTCGCCCTCTAAAGCAAAACTCCAGTTTCCGCCCAAACGCGGCCAAATAGTTCTGCGGCGCAGGCGCAGATTGAGCACGCCCGTTAAGCGAGCAAAGCGCATCGTGCGGAAGACGTCGGAAATGACAAAAGATGCGCCAATAAAAGAGCTAAATATAAAACCGGAAGCGGAGCTGTCCAATGAACATACGAAACTCGCAGATGAAGCGCATTTAAACAACAACTCGGAGGAGGCACCATCGAGCAGCACAGATGAATCCTCGACCGCCAGCTGTGGCACTGAGGGGGCAGAAGAAGATGACAGCAAGATGACTGAAATAGAAAAAGATCCCAAAGCAGAAAATAAAACTGAGGAGGAAACAATGCCAAATGAGCAATTGCAGAGCCCAGCCAAAGTAATAATTGAAACGACTGAAACACTGAGAGAGGAAGCAActgaaacaacagcagctgaggAAGAGATCGAGCAAGCTGTGACTCCAGTGCAGTTCGAGGAGTTGACCTCGTCAACAGAACAAATGGCTCCTGGAGTGCCGTCGCCCGAATGCGAGGTGGAAGTGAGCATGACATCAGGGAATGAGTTGATTGTGAGCATTCCACTGGAGGCGCTCGACGATGAGCTGCAGCACAAACTGTGCAATGCCGAGCCAGAGGCAGAGTCTGAGGCTGAGGAGGGAGAGAAGggagcagctgctggcaaGGAGAACGGCGAGATCGACGATGTGAATAACAATGCGAATGTCGAGCATTTTTGCCAGAGTGCTACAGCAGTTAGCTTCAATTCTGCTGTGGCACTCGATACCAAAGAAATTGAAGCAGAACCCGATGGAGGAGGAGTTGATGGTGGAGGAGAAGGAGGCGGCGTGGATGATGACATGGCATCACTAGAAAGTCTAGTGGAGCTACCAAAGCAAACAGTTGAGGAGCCACTGCCTACTCGCCCAGCTGCCAGCTCGATGGACTTTTTGGCCGAGTTCGAGAAGCACTGCGAGAAGACGCTGAAGCAGCAGACGGCGCCATGCGAACTCGAACTGGAGGAGGCCAAGCAGCAGATGCAGGTGGAGATGAACGATGTGGAGAGCACGCTGCATGGCATTCTCAACGAGATGCAGGATCAGCATCTCTACACGCCCGTCTGCACGCCCATCGATGAGTTCCTGACTCCCGCCGACTATGCGCCGCTCAGTGCAGACTCGGAGTCGGCGCCGCCAACGCCAGTGAATGCCACCGATCTCTACCACGAGGCGGGCGTggtgaagcagcaacaacagcagcagcagcaggtgaaGGAGGGCAATCTGTTTGATAGCAGCAACTTTAGCAATGAGCTGATTGGCTTCCAAAACGATATGCCCTGCTTCGAGAACATTGAGGCCTCGCCTGAGTCGATGGCGGCGCAGCAGAgtctgcagctggagctgacGCAGCTACTGGACGATTTGCAGCCGCCCATCGGcaccagcaacaccagcaacaccagcagcagcagccaacaacagcagcagcaaccgcaaTTGCTGCAGCCGGAGACTATCAGCTATGACGAACTGTATCCCACTGCGCCTGCAGCAACGCCAGTAACAACACCCGGGTCGCCGCCATCCGACAATGGTTCGAGTAAGCTGCAGCTCATCCAAATGCAGCCGCAAGAGCCGCTGTGGCAAGCACAAGCTGCCGCTGCAGTCGCCGCTGCTGCAACTCACCAGACGACACATTTGCAATGGTCAACGGTGGGTGGCCTGGAGGCCGTCAAGACACTGCCCCCGGCCAATTTGGACAGCGCGgcgacaactacaacgacgTACTACATCAATGCCAGTGATCTCTACCAGCAGTCGGGCAACTTGGCCAGCGACGGCTACGCATTGCTGGACAACAATGAGAACTACATAatggagcaacagcagcagcagcaacaacagcagcagcagcaacatcagcagcagcagcaacaacccaTTATGATACTCATACAGCAGCCAGAGCTGCAGCAGCCGGTGGCATCAGCGAGCAACCCGCAGCAGGCGCCGTTGCACATCACCTATGGACCAACGCTGGCCAACGAGCTGCACGGCTATCagacacagcaacagcaacagtcccaacagcagcaacagcaggcggtgcaacaacagcagccgccgccacaacgccagcagctgcagcagcagcaacaagtacaaaattcaaatcaaacagTATTAGGCTTGCCAGCACTTGTGGCGCCACCGCCACCTCGGGGCAGGCCGCCAATGTTGAAGTGCCGCTTCTGTCAGAACGGTCCGCGCTTCTCGAACAGCTTGGAATACAGTCGTCACATCATCGAGCTGCATCCCGCGGTGGCGCCCTTCAACTGTCCGCACTGCCCGCAATCGTTTGCCGGCCGTAGCAAACGCAACCAGCACATCTTAAGCCATCATGTGGTGCAGCAATTCCATTGCGGCCAATGCTCCCAGATGTTTCCCGCTCAGCGAGCGCTCGACTTGCATCTGCAGCGCTTCCACATGCCACTCACAACAGACGCAGCCGGCGACGGTGTGCGGCTAGAGGAGGTGCAGCTCCAGATAGCCACCaaggagcagctgcaacaacagccacaatcGTTGCAACCATCGGCACTACTGGCAGCACTTCAACAGCAGAAGAGTCCATCTCCGCCTCAGCCACGCAGGACGCGCATCCTTTGCTGCCCCGACTGCGAAGAATGCACGTCTGCAGCAAGCCATCAGCATCGCAAGGAGCAGCCCTATGAGGAGCTCAGCAATTTGCAGCCGCCGCCCACAGTGCTGACGCCACCCTCGACAATTGCGTCGCTGCCCTCGCCGCAGCCAGTGTGCCCGACGCCGCACATCACGCTGCCCTCGCCAGAGCAATCGGAGCCGGACTCGACAACGGCGACCCTGCGACAATTCCGTAAACGCTGCGTGCCCACAGGCAGTGCCATTGCGATGCCTACGACGACAACAGCGGCCCCCACAATGCTAATCACGGcagcgtcgccgtcgccctcctcgtcgccgtcgtcatcGACGATGGAGAACAGTGCAACGCTGCAGATGAGCAAACTACGCGGCAGCCATCAGTGTGTGGTCTGCGACAAGCGATTCACCAACATAATTGCCCTGCGCAAGCATCAGCAGCTGGCCCACGACTCGCAGACGACGATGCCGTGGGTCTGCTCGATCTGCAAGCGGGGCTATAGGAAGCGCACCGACATGGACAATCACATGAAGTCGCACGAGCCAAAGGGACGACCCTACGAGTGCAATGAGTGCTGGGTGCGATTCCCCGAGTTTAAGCAACTGGCAATGCACAAGTTCACCGTCCACGAACTGATCAAGCCGCATACGTGCGATGAGTGTGGTAAACAATTTGGTACGGAGAGCGCCTTGAAGACGCACATTAAATTTCATGGTGAGCGAGGCTTCCAGTGCGAAGAATGCGACGAGTCATTCTCAAATCTCAAAGAGTTTCGCAAGCATCGACGCACCCACAACAGAGAACTGTTTTACAAGTGCGAATACTGCCCACGTACTTTTCTGCATTTTACAAGCTTTCGTGCTCACATGAACACACACTTGCCGCTGGGCGTATTTCTTAACGATAAATCAACGGCTCAGCTGCCCAGCTGCCCCAAGTTGGAGTCTCCCAACGAGGAGTTGATGCCACTGACGCCGCTGAGCAACGTCCACAGCGGAGGCAGCATCAGCGAAGACTGCCCTGGTTCAGTTGAGATGGCTGAGAGCAGCGTGGCCCAATCGCTGGAGATGATCATCGATACGCCGTAA
Protein Sequence
MVAKFRRRCVRVQQRLQEYAQQIAQRQERRQPPQQQQLDKETNKQAISNLPESQPERKRRLEESPTVQSEASSPKLKRRNASHLATTMTTRNSKSRSPCKRINKPWRTKAARKQLSETWSTSSSSCLTTERSTATTAPVSNCPSSTSSSSGQTTPEHLSDLSVNPCRGFPSDGNSSTSLTNSDGQTTSPSKAKLQFPPKRGQIVLRRRRRLSTPVKRAKRIVRKTSEMTKDAPIKELNIKPEAELSNEHTKLADEAHLNNNSEEAPSSSTDESSTASCGTEGAEEDDSKMTEIEKDPKAENKTEEETMPNEQLQSPAKVIIETTETLREEATETTAAEEEIEQAVTPVQFEELTSSTEQMAPGVPSPECEVEVSMTSGNELIVSIPLEALDDELQHKLCNAEPEAESEAEEGEKGAAAGKENGEIDDVNNNANVEHFCQSATAVSFNSAVALDTKEIEAEPDGGGVDGGGEGGGVDDDMASLESLVELPKQTVEEPLPTRPAASSMDFLAEFEKHCEKTLKQQTAPCELELEEAKQQMQVEMNDVESTLHGILNEMQDQHLYTPVCTPIDEFLTPADYAPLSADSESAPPTPVNATDLYHEAGVVKQQQQQQQQVKEGNLFDSSNFSNELIGFQNDMPCFENIEASPESMAAQQSLQLELTQLLDDLQPPIGTSNTSNTSSSSQQQQQQPQLLQPETISYDELYPTAPAATPVTTPGSPPSDNGSSKLQLIQMQPQEPLWQAQAAAAVAAAATHQTTHLQWSTVGGLEAVKTLPPANLDSAATTTTTYYINASDLYQQSGNLASDGYALLDNNENYIMEQQQQQQQQQQQQHQQQQQQPIMILIQQPELQQPVASASNPQQAPLHITYGPTLANELHGYQTQQQQQSQQQQQQAVQQQQPPPQRQQLQQQQQVQNSNQTVLGLPALVAPPPPRGRPPMLKCRFCQNGPRFSNSLEYSRHIIELHPAVAPFNCPHCPQSFAGRSKRNQHILSHHVVQQFHCGQCSQMFPAQRALDLHLQRFHMPLTTDAAGDGVRLEEVQLQIATKEQLQQQPQSLQPSALLAALQQQKSPSPPQPRRTRILCCPDCEECTSAASHQHRKEQPYEELSNLQPPPTVLTPPSTIASLPSPQPVCPTPHITLPSPEQSEPDSTTATLRQFRKRCVPTGSAIAMPTTTTAAPTMLITAASPSPSSSPSSSTMENSATLQMSKLRGSHQCVVCDKRFTNIIALRKHQQLAHDSQTTMPWVCSICKRGYRKRTDMDNHMKSHEPKGRPYECNECWVRFPEFKQLAMHKFTVHELIKPHTCDECGKQFGTESALKTHIKFHGERGFQCEECDESFSNLKEFRKHRRTHNRELFYKCEYCPRTFLHFTSFRAHMNTHLPLGVFLNDKSTAQLPSCPKLESPNEELMPLTPLSNVHSGGSISEDCPGSVEMAESSVAQSLEMIIDTP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00509359;
90% Identity
iTF_00509359;
80% Identity
-