Dimm013372.1
Basic Information
- Insect
- Drosophila immigrans
- Gene Symbol
- -
- Assembly
- GCA_963583835.1
- Location
- OY757144.1:5070731-5075210[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 8 0.081 5.4 7.7 0.1 1 19 390 408 390 411 0.78 2 8 0.00026 0.017 15.5 0.7 1 23 691 714 691 714 0.96 3 8 6.3e-05 0.0042 17.5 3.1 1 23 732 754 732 754 0.97 4 8 1e-05 0.00067 19.9 2.0 1 23 760 782 760 782 0.96 5 8 2.1e-05 0.0014 19.0 1.1 1 23 788 810 788 810 0.98 6 8 0.00018 0.012 16.0 1.4 1 23 816 838 816 838 0.98 7 8 0.0029 0.19 12.2 0.0 2 23 845 866 844 866 0.96 8 8 0.018 1.2 9.7 0.6 1 21 872 892 872 893 0.95
Sequence Information
- Coding Sequence
- ATGGCGCTGGCCGTTGAGGAAGTGCGCCAGAAATGTGGCACCGTCTACACCTGGAATTGCGCTGGCGAACTCTACGGCATCGAGTGCGAACTGTGCGAGGAGCGTCCGCTCTGCGCCCTCGATGAGTTCGCCGAGCATATGGAGCTCTGGCATTCCGATTGGCAACAATCGGAatcgtcggcgtcgtcgtcatcgtcatcgttatTGCTATCGCCGGCCATCGAGGATGAGCTGATGCACGAAGTGCTCGCCGAACAGCAACAGTCCAGCTGTCCaggcgacgacggcggcgaGGTCAATGAACTCAAGCAGCAGCTCGTCCAAGAACTGAATGCCCTTGACACGCAGCAGCCAACGAcggcgacgctgctgctgacgtCGCTGCCGCAGCAGGAACAACAAGTACaacaagtgcaacaacaacaacagctgctgctcgtcGATACGCTCGGGCCCAGCGAACGGGCGCAACTTCGCAGCGATGACGCCGCCACGCCACAGACGACGGAGGCCAGCCAGAAGCTGTCCACGGAGCACGTGCAGCAGCTGATCGAGCTGTACCGCGCGGAGACGCGTCTCTGGAACCAGACGCACGCCGAGTTCCGCAACATGGAGCTGTGCCGCGACTCGTGGCGCCGCATCACCGCCTCGTGGAGCGCACACTGCGGCCGCAGCTTCAGCGTGACCGAGGTTCGAATCCGGATCTCGACGCTGTGCCAGCGCTTCATCAAGCAGCGCGAACGCCTGGATGCCGAGGGCGAGCTGGAGGACAGTGCCACATTTGTGCACTACGAGCAGCTGAAGTTCCTCAGCGAGCAGCAGGCGCTGGTGAAGCGTCAGGAGCACTTTGCACGCGAGAATCGCAAGCTGCTCGAGATCTACGAGCATTATCCGATCCTGTGGCACAATGCGCACAAGCGATTGCGTTGCGTCGACACGATGCGGCAGCGTCACGATGCCCATCGCGGTCTCCAGCTGGCGCTGAGTATGTGTGGCATCAAGCTCTCCGGTCTGGCGATGCAACGGCGGCTGCAATCGTTGCGCAAGCGGTATCGGCTGGAGAAGATTCGGTATTTGCACAGCGTGGTCGAGGGCAAGCAGCTGCAGTTCGTGTCCAGCTTCGAGCACTATGCGGAGATGGAGTTTCTGCACAAGCACATCGATCCGTATGTGTGTGCGGTGTGCGGCAAGATCTTcgagcagctgctcaaccatcAGACGCACGTGCAAAGCGGCTGCGaggggcagcaacagcaacagcaacagcagctggacgTGCAACCGAAGGCGGCGGCGACGCTGGGCGAACTGATCTTGGGCGAAGCCGACTTGCCACAGCTGGCCAGCAAGCCGGAGGACTTGCAGCCCGCCGAGGAACTGCAGCCGCCGCACAGCCTGGCCAAGGTGGAGGAGCAGAGCAGCCACAACGGCGGCAGCAACTTGCGTCTGAGCCTGCCGCAGACGCACAAGCTCATCGAACTGTATCGCGGCCAGCCGCAGCTCTGGGATCCCAATCACCTGGACTATCAGGCGCGGCCGCAACGCCGCCAGGCGTGGCAACAAATCGCCAGCGAACTGAACGCCTTCGCGGAGTCCAGCTACAGCTGGCAGATGTTGCATCGCAAGCTCACCGATTACATTAAGTACTATCGCAGGGAGCGGCAGCGGAAGCATGCCACACGCAGCTGGAGCTTCTATGCGGCATTCAGTTTCCTGGACGACATTGTGCCCATCAGCTGCGAGCTGCAGAAGACGCTGCAGCAGCGCGACAGCAATCTAAAGATCATCCAAGTGTATCGCAGCTACGAGCAGCTGTGGTGCACACAACATCCCGACTACACCAAGCGCAAGCAGCGTCAGCGGCAGCTCGAATCGTTGTGCAACCGCCTGCAGGAGGAATGCAACCTCCAGCTGAGCCTCGAACGCTTGCGCAATCGTCTGATCGAGTTCCGCTGCCAGTATCGACAGTGCAAGCAGTCGCGTCTCGAGGCCGTGCAACATGGCGCGATGTGGCAGCCCAGCTACGAGTATTACGAGCAGTTGCAGTTCCTCGAGCAGCATGTGGCGCCGTTTGCCTGCGGCTTCTGTGCGGCAAGCTTCAAGCGACGCTCCGACTTTGTGCGCCACCAGCGGCAGGTGCACGtcgagcagcagcgacgctcGTGCAACACGAGCGCCGCCAATGCGCTCGAGCACATCTGTCACATTTGCGGCATGAAGTTCTCGCTGCGCACCAGCCTGCTGGCGCATCTGCGTCGCCATCTGGGCCAGCGCACGCACGCCTGCAACGAGTGCCCCAAGAAGTTCTTCAACTCGACCGCGTTGCGGGTGCATCAACGCAGCCACACCAAGGAGCTGCCGTATGTCTGTGAGCATTGCGCTCGGGGATTTGTTAATGCCAGCAAATTGAATCAGCATCTGAAGCGTCATGCCGAGCAGCGCGATTATCCGTGCAGTCGCTGCGACAAGGCCTTCTATACGGCCCACGAGCGGGATCGCCATATGCGCGCCCATCTGAACATCAGGGACAAAGTGTGTCCGTATTGCGATCGCGCCTTCGTTGTGGGCAGCGCCTATTATGCCCATCTCAATCTGCATCGCGGCGAGAAGCGTTACAGCTGCTCCAACTGCGCCCAGCGATTCGCCCAATACGCGGGCCTTTATAAGCATCGCAAGCGCTGTCCTCCCAATGCCAGCAACGAGAATGGCAACACCAATAACACGTAG
- Protein Sequence
- MALAVEEVRQKCGTVYTWNCAGELYGIECELCEERPLCALDEFAEHMELWHSDWQQSESSASSSSSSLLLSPAIEDELMHEVLAEQQQSSCPGDDGGEVNELKQQLVQELNALDTQQPTTATLLLTSLPQQEQQVQQVQQQQQLLLVDTLGPSERAQLRSDDAATPQTTEASQKLSTEHVQQLIELYRAETRLWNQTHAEFRNMELCRDSWRRITASWSAHCGRSFSVTEVRIRISTLCQRFIKQRERLDAEGELEDSATFVHYEQLKFLSEQQALVKRQEHFARENRKLLEIYEHYPILWHNAHKRLRCVDTMRQRHDAHRGLQLALSMCGIKLSGLAMQRRLQSLRKRYRLEKIRYLHSVVEGKQLQFVSSFEHYAEMEFLHKHIDPYVCAVCGKIFEQLLNHQTHVQSGCEGQQQQQQQQLDVQPKAAATLGELILGEADLPQLASKPEDLQPAEELQPPHSLAKVEEQSSHNGGSNLRLSLPQTHKLIELYRGQPQLWDPNHLDYQARPQRRQAWQQIASELNAFAESSYSWQMLHRKLTDYIKYYRRERQRKHATRSWSFYAAFSFLDDIVPISCELQKTLQQRDSNLKIIQVYRSYEQLWCTQHPDYTKRKQRQRQLESLCNRLQEECNLQLSLERLRNRLIEFRCQYRQCKQSRLEAVQHGAMWQPSYEYYEQLQFLEQHVAPFACGFCAASFKRRSDFVRHQRQVHVEQQRRSCNTSAANALEHICHICGMKFSLRTSLLAHLRRHLGQRTHACNECPKKFFNSTALRVHQRSHTKELPYVCEHCARGFVNASKLNQHLKRHAEQRDYPCSRCDKAFYTAHERDRHMRAHLNIRDKVCPYCDRAFVVGSAYYAHLNLHRGEKRYSCSNCAQRFAQYAGLYKHRKRCPPNASNENGNTNNT
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00614398;
- 90% Identity
- iTF_00614398;
- 80% Identity
- -