Dimm013390.1
Basic Information
- Insect
- Drosophila immigrans
- Gene Symbol
- -
- Assembly
- GCA_963583835.1
- Location
- OY757144.1:5425110-5426387[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 8 4.7e-07 3.1e-05 24.2 1.8 1 23 142 165 142 165 0.98 2 8 0.00058 0.038 14.4 2.0 1 23 172 195 172 195 0.96 3 8 0.0021 0.14 12.7 0.5 1 23 202 227 202 227 0.95 4 8 2.2e-06 0.00014 22.1 1.0 1 23 239 262 239 262 0.98 5 8 0.0035 0.23 12.0 1.0 1 23 314 336 314 336 0.97 6 8 7.6e-06 0.0005 20.4 0.2 2 23 342 364 341 364 0.95 7 8 0.00052 0.034 14.6 2.0 1 23 370 392 370 392 0.95 8 8 7.5e-06 0.00049 20.4 1.5 1 23 398 420 398 420 0.98
Sequence Information
- Coding Sequence
- ATGCGACCGCTGCTGAATGGCAACCAGTGCTTGACGTGTCTGCTGACCAGCGACGGCCAGATGTCGCCGCCACACACGATTGCGGACGACGCCGagctgcagcaactgctgcagcgACATCTCGACTGGCAGCCGGAGGAACTGAGCGCCGAGCAGCTGCCCAAGCGGCTGTGCCACGCCTGCCACGAGCTGTTGCTGAGCTACGAGCGCTTCCAGCGGCAGGCACGCGACTGCCGCCAACAGCTGCTTACAATGCTACAGCAAACGGCCAGCTTCGAAGTCGTCTACGAGCAGGAGACGCTGCCCAAGGCAGATGAGTTGCTCACCAGTGAAGAGGGCAATGCAACGCCGACGCCACAGCCCGATCCGTTCGACGAGCCAGCTGCTGCGCAGCCACGTCGCTGCAAGGGGCTGAAGAACCGCTTCAAGTGCCCGCAATGCGGACGCTGCTTTGCCCACCAGGTGACGCTGGCGGCGCACGTTCGCAAGGTGCACGAGGGCAGCAAGCGGCCGTTTCAGTGCGATCGCTGCGACAAGTGCTACAGCTTCATGGGCGGCCTCTACACGCACATCAAGGAGATCCACGACACCCCCAAGCGCTCCTATCCATGCGATCAGCCCGGCTGTGAACGCGTCTACATCAGCTGCGTGGCGCTCCAGAAGCACAAGCGGCTGAAGCACAGTCCGTTGCTGCCACCAGCCGCGGCACGCAAATATGTGTGCGAACAATGCGGCGCCACCTTCAATCAGACGGCGAATCTCAAGTATCATCGACGGACCAAGCATCCCACGGCAGCGGAGGCGGCAGAGAATGCCAGCGACAGTGCTCGACACTTTTGTGTGCCGTGCCAGAAGCATTTCCATTCCCGCTACACGCTCAAGTACCACAACATGCAGCAGCATGCGACGAACGAGGATGACGCCGCGTTGCAGGCGCAGCACGAATGCCAGGTCTGTGGACGTCGGATGGCGAAGAGGTTTATGCTGGTGCAGCACATGCTGATGCACAGCAACGACAAGCTGCCGTGCGAGCATTGCGGCAGGTTGTTCGCCAGGAAGTTCGAGCTGGAGGCGCACATCCGGGCAGTGCATCTGAAGCTGAAGCCTTTCGCCTGCAAGTATTGCGCCGAGTCGTTTGCATCGAGGAAGACGCTGCGGCATCACGAGTACATCCATACGGGCGAGAAGCCGTATGTGTGCCAGGTGTGCGGGCAGGCGTTCCGGCAGCAGACGTGCCTCAAGAACCATGGCAAGGTGCACGACAAAGCGACATGTTGA
- Protein Sequence
- MRPLLNGNQCLTCLLTSDGQMSPPHTIADDAELQQLLQRHLDWQPEELSAEQLPKRLCHACHELLLSYERFQRQARDCRQQLLTMLQQTASFEVVYEQETLPKADELLTSEEGNATPTPQPDPFDEPAAAQPRRCKGLKNRFKCPQCGRCFAHQVTLAAHVRKVHEGSKRPFQCDRCDKCYSFMGGLYTHIKEIHDTPKRSYPCDQPGCERVYISCVALQKHKRLKHSPLLPPAAARKYVCEQCGATFNQTANLKYHRRTKHPTAAEAAENASDSARHFCVPCQKHFHSRYTLKYHNMQQHATNEDDAALQAQHECQVCGRRMAKRFMLVQHMLMHSNDKLPCEHCGRLFARKFELEAHIRAVHLKLKPFACKYCAESFASRKTLRHHEYIHTGEKPYVCQVCGQAFRQQTCLKNHGKVHDKATC
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00614369; iTF_00509282;
- 90% Identity
- iTF_00614369; iTF_00509282;
- 80% Identity
- -