Dimm005574.1
Basic Information
- Insect
- Drosophila immigrans
- Gene Symbol
- -
- Assembly
- GCA_963583835.1
- Location
- OY757141.1:49152785-49154239[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 0.013 0.84 10.2 1.9 1 23 143 165 143 165 0.97 2 9 0.00012 0.0076 16.6 2.5 1 23 171 195 171 195 0.97 3 9 0.00073 0.048 14.1 1.7 3 23 204 227 203 227 0.92 4 9 3.7e-05 0.0024 18.2 1.0 1 23 236 258 236 258 0.97 5 9 0.00015 0.01 16.2 1.7 2 23 267 290 266 290 0.94 6 9 0.00023 0.015 15.7 1.6 1 23 296 318 296 318 0.97 7 9 0.00012 0.0077 16.6 1.4 2 23 325 347 324 347 0.96 8 9 0.0005 0.033 14.6 0.8 1 23 353 375 353 375 0.97 9 9 3.8e-07 2.5e-05 24.4 0.3 2 23 382 403 382 403 0.97
Sequence Information
- Coding Sequence
- ATGACGTCCACAAATAGTTTACACAAGTGTCGTGCTTGTCTCGCGCCACAGGAAGAGGATGATATAAGCTATGACATGCGTTTATTGCCTTTGTTGGCGTACAAGTATTTAACATGCACAGATTTGTCCATTGAGGAGGAGGATTCTCTGCCAAGTGAGCTTTGCGAGGACTGCACTGGGCAGCTGGAGCAGTTTAATGCGTTTCGGGAGCGATGCATTGCAGCAGACAAGCAGCTGCGGGTGGAGAGAGATACGAATTTCCAAGAGATGCCATTTGAAGCTGAATTACAAGATGCAGAAGTCAACAATCTGCAGCTGTGTAATGCGAGAGCCACAAGAAAGCGACGAGTgagaaagcaaagcaaagaggCTGAAGAAGAAGCTTTTAACAAGGATTTAGAGCCGGTTGTGGGGCAGAGCTCCTGCTACAAGTGCGACATTTGCGACATGCGCTTTCTGGTGGAGCATCGTCTGCAGGCGCACAAGCGACAGCACGAGGGACTGATGCCCTATCCCTGCACGGAGGATGGCTGTGATCGAGCCTTCAACCGGCAGCACTGTCTGTCGGAGCACCTCAGGCAGCACTCGGGCACGAGTCGCTGGTTTGGCTGCGAGCAGGAGGGCTGCAGCAAACGCTATCGCCACAAGCCGACGCTGATGATGCACATGCGACGCAGCCACAAGCTGGGCCCTGAGCTCAAGTCGCATGTCTGTGAGTTCTGTGGCAAGGTGTTCAACTCCTCGGCGGTGCTCAACGATCATCGCTACACGCACAAGGACAAGTCTGAGCTGCCACACGCCTGCTCCGAGTCGGACTGCCAGCGACGCTTCGCCAGCAAGGAGAAGCTCAAGGTGCATCTGATGCGTCACGCGGGCATCAAGAACTTCAGCTGCCCCTATTGTGGCATGCGCAAGACCACAAGGAACGAGCTCAAGAGCCACATGAACTATCACACGCTGGAGCGCACTTGGCCCTGCCGCTTTTGCTCGAAAGTTTGCAACAGCTCTGGAAATCTCAAAATGCATGTTCGCACCGTGCACGAGCGGGCCAGAGATTATGCCTGCAGCTACTGCGAGCGCAGCTTTGCCAAACCGGATACCCGCAAGTACCACGAGATGACGCACACCGGCGAGAAGCCCAACGAGTGCGAGGAATGTGGCAAGCGATTCACGCAACCTGCGGCACTCCGAACGCATCGCAAGATTCATGAGCGACAGCGCAAGGAGGCGGATGCCAGCTTAACTGTTGTCGTGGCACCTTCGACTCCCGATGGTGATAACAGTTAA
- Protein Sequence
- MTSTNSLHKCRACLAPQEEDDISYDMRLLPLLAYKYLTCTDLSIEEEDSLPSELCEDCTGQLEQFNAFRERCIAADKQLRVERDTNFQEMPFEAELQDAEVNNLQLCNARATRKRRVRKQSKEAEEEAFNKDLEPVVGQSSCYKCDICDMRFLVEHRLQAHKRQHEGLMPYPCTEDGCDRAFNRQHCLSEHLRQHSGTSRWFGCEQEGCSKRYRHKPTLMMHMRRSHKLGPELKSHVCEFCGKVFNSSAVLNDHRYTHKDKSELPHACSESDCQRRFASKEKLKVHLMRHAGIKNFSCPYCGMRKTTRNELKSHMNYHTLERTWPCRFCSKVCNSSGNLKMHVRTVHERARDYACSYCERSFAKPDTRKYHEMTHTGEKPNECEECGKRFTQPAALRTHRKIHERQRKEADASLTVVVAPSTPDGDNS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00614364;
- 90% Identity
- iTF_00614364;
- 80% Identity
- -