Dimm005371.1
Basic Information
- Insect
- Drosophila immigrans
- Gene Symbol
- -
- Assembly
- GCA_963583835.1
- Location
- OY757141.1:47252879-47255026[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.002 0.13 12.7 1.6 2 23 215 236 214 236 0.97 2 12 0.0083 0.54 10.8 3.2 1 23 242 267 242 267 0.94 3 12 4.9e-05 0.0033 17.8 0.5 1 23 274 299 274 299 0.95 4 12 0.0013 0.089 13.3 3.6 1 23 307 329 307 329 0.97 5 12 0.00082 0.054 13.9 0.4 3 23 338 358 336 358 0.98 6 12 0.003 0.2 12.2 0.1 1 23 364 386 364 386 0.98 7 12 0.021 1.4 9.5 3.0 1 23 392 415 392 415 0.97 8 12 0.0056 0.37 11.3 3.8 1 23 421 443 421 443 0.95 9 12 0.0025 0.17 12.4 1.0 1 23 449 471 449 471 0.97 10 12 0.00017 0.011 16.1 0.0 3 23 532 553 530 553 0.95 11 12 0.00048 0.032 14.7 5.8 1 23 559 581 559 581 0.98 12 12 3.5e-05 0.0023 18.2 0.8 1 23 587 609 587 609 0.98
Sequence Information
- Coding Sequence
- ATGACTGAGGAGAAATTGGGCTTAGCCCAATCACTCTGTCGCACGTGCTTAGCAAAGCTAAACGATGATGAAGCCTTCGACATCTTCATCGTGCCCGGCCTGGCCAAGAAATTGTGTGTTTGCACTTCGCTGTCCGTGGAGCAACAAGACGGATTTCCCAGCAACATCTGCCCCGCTTGCTACTGCCGACTCAACGACTTGCATGACTTTCAGGCACAATGCGTGGCCTCGATGCAAAAGTTCAGAGAGATGGCAAGCAGCTGCTTCATAGTCCGCTCAATTCCAGAGGACAACTTTAATGTGGTGAATGCAGCTGACCAAGATGCGGAGATCGTTGCCGAGGAAGCGGAGGAGCTACACTTTGATCCATTGCAAAATACCAAAATAGAAATTGACGAGCAAGATGTGTTCAAGATGATAGAAGCTGTTGATAAAGAAACTGACGAGGAACGGGTCGGCGATGGCGACGACAGCGATGACAATGAAGGTATTGACTTCGAGGCGGACAGCAGCGACTGTGATTACGCGTTGCCGCTGTCACGCCTCAAAGGCAAAGCCAAGGATCGGAAGGAAACCACAGCAACTGATAAACCAAAGAGGAAGCGATTACCGCCAGCAGAGCGAGAGCGTCGTCGGTTGATTGAGTGTCATATTTGTACGCAGAAGTTCATGAAGGTAGTAAACTATGAGGAGCACATGAAGCGGCACAGTGATCTGTTGCCCCATCAGTGTCCCGTGGAGTCTTGCAAGACGGGTTTTACGACAGCCAATGGACTGCGTCACCACATGGAGCACACGCACACGGAACTGTGCCCAATGTTTGCCTGCACTGCCAAGGAGTGCAACAAGCAGTTTCCATTGAAACGCTTGCTCACTAGGCATATGCGGGTTGATCACAACATTGCCAAGCCCGAGATACATCCGTGCTCCGAGTGCGACAAGATATTTCGCTGTCCCATGGCGCTCAAGAAGCACATGTACAAGCACACGGGCAAGGAGATGCCCTTTGGCTGTGATATATGCAAAAGACGCTTTGCCACCGGCACCGAGCTGCGAGATCATTTGCTGCGCCACGCGGGCATTAAGCGATTCGTGTGTCCCTATTGCGGGGTGGGCAAAACGACCAAACAGGAGCTGGATAATCACATCTTGACGCACACCAGGGAGAAGAACTTCAAGTGCGATCAGTGTGATTATGCCACGCATATCAAGCAGTCGCTGACTAAGCATATCCACGTGGTGCACATGAAGATCAGGAAGCACGCCTGCAAGCACTGCGAGAAGACCTTTGGCACTGCGTATGCTCGCAGGACACACGAGAGATTGCACACGGGAGAGAGTTGCTTCGAGTGCTCGATCTGCAGCCGAATGTTTCTCTTCGAGAAGAACTTAACAAATCACTTGAAGGCTCACGAGAAGCGTGAGAAGAAGGCTGCTGAAAAGGAGGAAAAGAAAAAGGAGCGGCAGATTAAATTAGGAGCACGAGTTGAGCGTGTGGATATCGAACGATTGGCTGGCACCGTCGTCAATCCCATTCCCAAAGTGTCGCTGCCAGCATGGTCGGAAATCGAGAAGCGGGATGGTCAGGTGATATGTCCGGAGTGTGGCAAGGCCTTCAATCGCATAGAAGGCATGAAACTTCACTACAAAGTGGTGCATCAAAAGATTAAGGATTACATCTGTCGCTTTTGCCACAAACGCTTCGCGAGGCTGCATTACCTGAAGGCTCATGAGAATACGCACACCGGGGCGACGCCTTACAAGTGCGACATCTGTGGCAAAGCATTCAAGGCGGACTCGACGCTATACACTCACAAACAGTCCCACAATAGGCCTCCTAAGCCACCCAAGGCGCCAAAGCCTGCTAAATTAGTTAAgcaaccaaaaaccaaactgAATACGCAGCCGAATAAAATCCGCGAAGAGTTCGTGGATCCAGCTGCAGCACGTGCGGCGGCCCGAGCGCAGTTGATTATCCATCAGGAGAACAAGAATGAGATCAAGTTGAAGGCGGCCGAAAAGATACAAAAGATTCAAACTGCGGCTCAGGAGCAACTTCAGCTGTTGAAGCGGCTGGGTGAAAAAATGTCCTATGATGATTTACCTAAACCTGATAATTGCTTGAACATTCCCAAGGATCATGTATAA
- Protein Sequence
- MTEEKLGLAQSLCRTCLAKLNDDEAFDIFIVPGLAKKLCVCTSLSVEQQDGFPSNICPACYCRLNDLHDFQAQCVASMQKFREMASSCFIVRSIPEDNFNVVNAADQDAEIVAEEAEELHFDPLQNTKIEIDEQDVFKMIEAVDKETDEERVGDGDDSDDNEGIDFEADSSDCDYALPLSRLKGKAKDRKETTATDKPKRKRLPPAERERRRLIECHICTQKFMKVVNYEEHMKRHSDLLPHQCPVESCKTGFTTANGLRHHMEHTHTELCPMFACTAKECNKQFPLKRLLTRHMRVDHNIAKPEIHPCSECDKIFRCPMALKKHMYKHTGKEMPFGCDICKRRFATGTELRDHLLRHAGIKRFVCPYCGVGKTTKQELDNHILTHTREKNFKCDQCDYATHIKQSLTKHIHVVHMKIRKHACKHCEKTFGTAYARRTHERLHTGESCFECSICSRMFLFEKNLTNHLKAHEKREKKAAEKEEKKKERQIKLGARVERVDIERLAGTVVNPIPKVSLPAWSEIEKRDGQVICPECGKAFNRIEGMKLHYKVVHQKIKDYICRFCHKRFARLHYLKAHENTHTGATPYKCDICGKAFKADSTLYTHKQSHNRPPKPPKAPKPAKLVKQPKTKLNTQPNKIREEFVDPAAARAAARAQLIIHQENKNEIKLKAAEKIQKIQTAAQEQLQLLKRLGEKMSYDDLPKPDNCLNIPKDHV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00509260;
- 90% Identity
- iTF_00614350; iTF_00509260;
- 80% Identity
- -