Basic Information

Insect: Drosophila hydei
Gene Symbol: -
Assembly: GCA_003285905.2
Location: NW:3497414-3529449[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0052 0.3 11.2 1.8 1 23 1249 1271 1249 1272 0.95

2 8 0.45 26 5.1 1.0 1 23 1277 1300 1277 1300 0.96

3 8 0.00032 0.018 15.0 0.8 1 23 1509 1532 1509 1532 0.96

4 8 0.0041 0.23 11.5 0.5 2 23 1541 1562 1540 1562 0.97

5 8 0.04 2.3 8.4 0.3 1 23 1569 1592 1569 1592 0.96

6 8 1.6e-05 0.0009 19.1 1.4 1 23 1598 1620 1598 1620 0.97

7 8 0.00043 0.025 14.6 0.5 1 23 1625 1647 1625 1647 0.97

8 8 0.014 0.79 9.9 3.1 1 23 1653 1675 1653 1675 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0052	0.3	11.2	1.8	1	23	1249	1271	1249	1272	0.95
2	8	0.45	26	5.1	1.0	1	23	1277	1300	1277	1300	0.96
3	8	0.00032	0.018	15.0	0.8	1	23	1509	1532	1509	1532	0.96
4	8	0.0041	0.23	11.5	0.5	2	23	1541	1562	1540	1562	0.97
5	8	0.04	2.3	8.4	0.3	1	23	1569	1592	1569	1592	0.96
6	8	1.6e-05	0.0009	19.1	1.4	1	23	1598	1620	1598	1620	0.97
7	8	0.00043	0.025	14.6	0.5	1	23	1625	1647	1625	1647	0.97
8	8	0.014	0.79	9.9	3.1	1	23	1653	1675	1653	1675	0.99

Sequence Information

Coding Sequence: atgagTGCCAACAATCGACGacgtagcaacagcagcagcaacagcagcaatcgcCAATTGGCCACAGCTGACCGAATGAATGCAGCTATGGGTGTACGCGATGTCGGCGTTGGCGGAGATAGCggatttaacaaatttgacgCCAGCAGCGTTGACGACGCCAGCATAGGGGAGCTGCTTGAGATGCCGCGCGtgtgtcgctgttgttgtaaaGGCGACATGGAATTGCTGAGCCTGTTTGAGGCCAGCGATGAGGCAGACAAAcagcagacaacaaaaaatcaacgCCGACGCAAAGCACCAACAACTCCAACAACTGCAGAagcaacacaacagcaacaatatcaaCAGCGCAAAAGTGATAATCCCGTGGAATATGCGCTCAGCTGTGCGCATAGCAGCATGGACACTGTGCGAGAAGAGATGATCGTTTGGATGCTCAATATCTCATATAACGACGGCCTGCCCCAGGAGATATGTCGCCAATGTAAGGCGCAGTTTATAATGGTGGCCAAGTTCCGACGGCGCTGTTTGCGTGTGCAGCTGCGTCTGGAGGAGTACGCCAAGAAGATAGCCGAGCATAAACAAACTTTAGTAGCCAAGTTGAATAGCAGAACACAGTCAAATGATCTGCCTGCAGAGGATTACCTGCATTTGCCGGAGTCGCAAACTGAACGGAAGCGGCGGCTGGTGCTTGGTATGGAGACAGCACAGCCGGAACAGCAACCGGCGCCCAAACTAGCCAAGACTGAAGTCGATGTAGAGCTGCCGACAGCGTCTAGACTGCAACAGATACGAACGCGCAAAATGCGAATTGCCTCTTTGCCTGACACCAGAATTGAAGCTGAACCTGCGTCGGCAATAGCGACACGAAGTGTGTCCCAGCAGGGCGAAGCCAGGTTAAGGGAGGGAACTCCACACAGATCACCCTGCAAACGATCACGCATGCCCTGGAAAACGAAAGCGGCACGCAAACAGCTTTCCGAAACATTGTCGAGCTGCTCGATGAGACCCAACTGTCGAACAGACATTACGACATCGCCTGTGCTGCCAAGAGTCCAATTAATGTTTCCATCAGCGCCGAGTTCCGAAAATGAGACAGAAACACGCGATGGCCACACATCTCCGGAGCAGCTTAGCGATTTATCTGTTAATCCGTGTCGCGGCTTTGACAGCGATGGCCACAGCTGCTCGTCTTCAACTTCCTCCTGCATATCCGCTTCCTCATCAACAGCTGTGAGCGCCGGCCAAAAGGCGACAACGCCGAATGCCAAGCTGAAGTTTCCACCAAAACGTAGATCGCCCAAAAATCTCATGGTGCTACGCCGTGGTCGTCGAACGCGAGTGACAGTCAAGACAGTGCCGCTCAAGCGTTCGAGGCGCATTACAggaaagaaacagaaacagacaaGACCTGAAAATCAATTGCCCGAAAAACATTTGATAGAACAGTCGAGCAACAATTTAATAGAGAAGCCGTCCGTGGATACAACCGCAAGTGAGACATTAGAGAAGTTGGCAAGTAGCTCTTCGGATGAGGCGCCGCACAGCAGCCCGGATGGTTACACTGAAGTCAACTCGGAGCATCAACTTCCAATTCCAACAGATGAGCTGCAGGCTGacttaagtaaaacagaagccAACGCGGTAAAGACCACTGTAGAAGTAATAGGATTTAGGGAACAGCAGGAAGCCGCCGCGACTGTGCAGGTGCAGTCACCAGCACCCTCAGAGCCAATCCAATCCTCTCCAGACAATGAAGTCAAAGAAACGCAGGCCATAATTCCAAAAGAAGAAGTAGAGAGCATATCAAAGGAAGTCAACGTGGAAAGCGAAGCTGAAGTTGTAGTAGCGATAGCAGCATCGAATGGAATTGCAGAGTCAGCTGATTCGACAGTACAATTCGAGGAGCTTACGTCGTCCACCACGGAGCAGGGCAAACAATCTCTGACGACCGACGGGACAGCAACAGAGTCAGAAGCAACGAATGACGAGCAAGAGCTGGAGGAAGAGCCACAGTCTGACGAGGAGACCAAGGAGTCGGAGCTTATAGTAAGCATACCCTTGGACATGCTAGACGATGACCTGCAGCGTAAGTTATGCAGCAGCACTGATGCACTGGCTGATGTAGGGCAGCCGGACAACGAGCCCAAAGAGCCTGCGGAGGCAGACGATGTGAACAACAACGAGAATAGCGAGCATTTTTGCCAGAGTGCTACAGCAGATAGCTTCAATGCTGCTGTAGCACTCGCaaccaaacaaattgaagcaGAACCCAATGGGGGCGTGACGATAGTGACAACGCTAGATGACGATATGGAGTCACTGGAGCGATTAGCCAATATGCagcagaatcagaatcagccAGTTGACGAAGTGCAGGTGCCACGTGCTGGCCATGCCAGTTCCATGGACTTTTTGGCCGAATTCGAAAAGCACTGCGAGAAGACGCTCAAGCTGCAGGCGCGTCAACCAGTGCCGCCACTTGAAGTGGAGCTCGAGCTGGTCGACGCCAAACAGCAGTTGGAGGTGGAAATGAATGATGTGGAGAGTACGCTGCATGGCATACTCAATGAGATGCAGGATCAGCATCTCTACACGCCTGTCTGTACGCCCATCGATGAGCTGCTGACGCCTGCGGATTACGTGGTACTCAATGAAACGGAGACGACAGTACCCACGCCTGCCCCGCCGCAGCTGTACGAGCCGCCAGCTGAGACAACGCAGGCACAGCAGCCACAGGTGAAAGAGGGAAATCTATTCGATAGCAGCAATTTCAGCAATGAGCTGATTGGCTTCCAAAACGATATGCCCTGCTTTGAGAACATTGAGGCAACGCCCGAGTCGGTGGCAGCGCAGCAGAGCCTGCAACTGGAGCTGACGCAGTTGCTCAATGAGCTGCAACCAGCACAACAGCCATTGCAACcggtgcagcagcaacagttgcagatACAGCCGGAGGCAGTTAGCTATGAGACACTGTATCCTGCAGCACTGCCCGCTCCCTCGGCGAATAGCAACAAGTTGCAACTGATCCAAATGCAGCCACAGGAGACGGTATGGCAGGCACAGGCAACCGCCGCCCAACAGGCGACAGCCACACAGCTGCAGTGGTCGACGGTGGGCGGCTTGGAGGCCATCAAGACAACACCTGTTGCCGGCGTGGATACTCTGGACGGTAGTGGCACAACCACCTACTATATCAATGCCAGTGATCTCTACCAGACGCAACTGCAGCCGCAAACGACGCAGCTGACGAGCGATGGCTATGCGCTGCTGGACAGCAATAAGAACTATGTGCTTGAGTCGCAGGATCAACAGCGATTGCCgcagtcacagcagcagcagcagcagcagcaacaacccaTCATGATACTCATACAGCAGCCTGAGCTGCAACAGCCTGTGGCATCCGCCAGCAAtccgcagcagccgccgctgcatATAACTTATGGCGGCAGTCTGAGCAATGAGCTGCACGCCGCCtatccacaacaacaattgcagcagcatcaacagcagcagcagcagcaacagctgccacagccacagacacaacCACAACTACAACGTCCGCAACAACAAGTACAAAATACAGTATTAGGCTTACCTGCTGTCGTGCCGCCGCCCACACGTGGCCGTCCACCCTTATTAAAGTGCCGTTTCTGTCAGAATGGACCACGCTTCTCCAGCAGCCTGGAATACAGTCGTCACATCATTGAGCTGCATCCGGCCGTGGCGCCATTCAACTGTCCACACTGCCCGCTGGCTTTTCCCGGGCGTAGCAAGCGCAATCAGCACATCCTAAGCCATCATATGGTGCAGCAGTTCCACTGTGGTCAATGCTCTCAGATGTTACCCTCGCAGCGAGCTCTAGATTTGCACCTGCAACGCTTCCATATGTCGCTGCCCACTGAgccaccagctgctgctggagtgCGACTCGAGGAGGTTCAATTGCAAATATCTAATAATACCGAACAGCCTaaacagcaccaccagcagcagcatccgcaGACACTTAGGCAACCACTgaaacagcagcaccagcagcataTGTCGGCATTGGAATTACAAACAAGCACCCAACAGCCACGCAAGACGCGCATACTGTGCTGCCCAGACTGCGAGGACTgCTCTTCGGCCAGTGGACACAATCATGGCAGAGGACAGTCGTCATATGAGGAGCTGTCCAACTTGCAGCCACCGCCAAATGTTTTAACGCCGCCTTCGACTATCGCATCGCTGCCATCACCGCAGCCGGCGCCGCACATAACGCTGCCTTCGCCGGAGCAATCGGAGCCGGACTCGACGACAGCCACACTGAGGCAGTTCCGCAAGCGCTGCATACCCAGCAACTGTACGACAGCAGGTACAGCTTCCATTtccacatcagcagcagcagcaacaacaacagcaacagcaatactATCAGCGGCTCCATCGCCGTCTCCGTCTTCCTCGCCATCCTCGTCGACAATGGAAACGGGCGCCACACTGCAGCTGGGCAAATTACGCAGCAACCATCAGTGCGTCGTCTGCGAGAAGCGTTTCACGAATATCATTGCGCTGCGCAAGCACCAGCAGCTAGCCCATGACTCACAGACAACGATGCCCTGGGTGTGCGGGATTTGCAAACGGGGCTATCGGAAACGCACCGACATGGACAATCACATGAAGTCGCATGAGCCGAAGGGTCGGCCGTACGAGTGCAATGAGTGTTGGGTACGTTTTCCGGAGTTTAAGCAGCTGGCCATGCACAAGTTCACCGTCCATGAGCTGATCAAGCCGCATACCTGCGATGAGTGTGGTAAACAATTTGGTACGGAGAGCGCCTTGAAGACGCACATTAAGTTTCACGGTGAGCGCGGCTTCGATTGCGAAGAATGCGGCGATGTCTTCGTTTATATGAAAGATTTGCGCAAACACCGTCGCAGCCACAACAACgaattattttacaaatgtgTCAACTGTCCGCGCACGTTTCTACATTTTACGAGTTATCGTGCTCATATTAATACCCACCTGCCGCTGGGCGTTTTTCTCAACGACAAGATGCCTAGCAGCGTAAATAGCAAACTGGAAAATCCGGCGATGCCAGCAACTGTCGAAGAGTCATCACTGCCCTTAACGCCGCTTAGCAACTGCAAtggcaacagtagcagcatcGATGATTGCCCAGGCTCCGTCGAACTGGTGGAAAGCAGCGTGACGCCTTCGTTGGACATGATTGTGGATACGCCATAA
Protein Sequence: MSANNRRRSNSSSNSSNRQLATADRMNAAMGVRDVGVGGDSGFNKFDASSVDDASIGELLEMPRVCRCCCKGDMELLSLFEASDEADKQQTTKNQRRRKAPTTPTTAEATQQQQYQQRKSDNPVEYALSCAHSSMDTVREEMIVWMLNISYNDGLPQEICRQCKAQFIMVAKFRRRCLRVQLRLEEYAKKIAEHKQTLVAKLNSRTQSNDLPAEDYLHLPESQTERKRRLVLGMETAQPEQQPAPKLAKTEVDVELPTASRLQQIRTRKMRIASLPDTRIEAEPASAIATRSVSQQGEARLREGTPHRSPCKRSRMPWKTKAARKQLSETLSSCSMRPNCRTDITTSPVLPRVQLMFPSAPSSENETETRDGHTSPEQLSDLSVNPCRGFDSDGHSCSSSTSSCISASSSTAVSAGQKATTPNAKLKFPPKRRSPKNLMVLRRGRRTRVTVKTVPLKRSRRITGKKQKQTRPENQLPEKHLIEQSSNNLIEKPSVDTTASETLEKLASSSSDEAPHSSPDGYTEVNSEHQLPIPTDELQADLSKTEANAVKTTVEVIGFREQQEAAATVQVQSPAPSEPIQSSPDNEVKETQAIIPKEEVESISKEVNVESEAEVVVAIAASNGIAESADSTVQFEELTSSTTEQGKQSLTTDGTATESEATNDEQELEEEPQSDEETKESELIVSIPLDMLDDDLQRKLCSSTDALADVGQPDNEPKEPAEADDVNNNENSEHFCQSATADSFNAAVALATKQIEAEPNGGVTIVTTLDDDMESLERLANMQQNQNQPVDEVQVPRAGHASSMDFLAEFEKHCEKTLKLQARQPVPPLEVELELVDAKQQLEVEMNDVESTLHGILNEMQDQHLYTPVCTPIDELLTPADYVVLNETETTVPTPAPPQLYEPPAETTQAQQPQVKEGNLFDSSNFSNELIGFQNDMPCFENIEATPESVAAQQSLQLELTQLLNELQPAQQPLQPVQQQQLQIQPEAVSYETLYPAALPAPSANSNKLQLIQMQPQETVWQAQATAAQQATATQLQWSTVGGLEAIKTTPVAGVDTLDGSGTTTYYINASDLYQTQLQPQTTQLTSDGYALLDSNKNYVLESQDQQRLPQSQQQQQQQQQPIMILIQQPELQQPVASASNPQQPPLHITYGGSLSNELHAAYPQQQLQQHQQQQQQQQLPQPQTQPQLQRPQQQVQNTVLGLPAVVPPPTRGRPPLLKCRFCQNGPRFSSSLEYSRHIIELHPAVAPFNCPHCPLAFPGRSKRNQHILSHHMVQQFHCGQCSQMLPSQRALDLHLQRFHMSLPTEPPAAAGVRLEEVQLQISNNTEQPKQHHQQQHPQTLRQPLKQQHQQHMSALELQTSTQQPRKTRILCCPDCEDCSSASGHNHGRGQSSYEELSNLQPPPNVLTPPSTIASLPSPQPAPHITLPSPEQSEPDSTTATLRQFRKRCIPSNCTTAGTASISTSAAAATTTATAILSAAPSPSPSSSPSSSTMETGATLQLGKLRSNHQCVVCEKRFTNIIALRKHQQLAHDSQTTMPWVCGICKRGYRKRTDMDNHMKSHEPKGRPYECNECWVRFPEFKQLAMHKFTVHELIKPHTCDECGKQFGTESALKTHIKFHGERGFDCEECGDVFVYMKDLRKHRRSHNNELFYKCVNCPRTFLHFTSYRAHINTHLPLGVFLNDKMPSSVNSKLENPAMPATVEESSLPLTPLSNCNGNSSSIDDCPGSVELVESSVTPSLDMIVDTP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00559818;
90% Identity: iTF_00502853;
80% Identity: -