Basic Information

Insect: Drosophila hydei
Gene Symbol: -
Assembly: GCA_003285905.2
Location: NW:4605012-4608990[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.0016 0.092 12.8 5.1 1 23 611 633 611 633 0.98

2 5 5.2e-06 0.0003 20.6 0.6 2 23 646 667 646 667 0.98

3 5 0.00039 0.022 14.7 1.7 3 23 676 696 675 696 0.99

4 5 0.00052 0.03 14.4 0.9 1 23 701 726 701 726 0.92

5 5 0.11 6 7.1 1.3 1 21 734 754 734 758 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.0016	0.092	12.8	5.1	1	23	611	633	611	633	0.98
2	5	5.2e-06	0.0003	20.6	0.6	2	23	646	667	646	667	0.98
3	5	0.00039	0.022	14.7	1.7	3	23	676	696	675	696	0.99
4	5	0.00052	0.03	14.4	0.9	1	23	701	726	701	726	0.92
5	5	0.11	6	7.1	1.3	1	21	734	754	734	758	0.91

Sequence Information

Coding Sequence: ATGATGGACCGTAAGAAGGTGCTTGAATTGGACAAAATCTGTCGCTTATGCATTTCGGAGCGCAAGGAAATGCGTCCGCTGTTTAGTGAAAAAGTGCCCGAAATGCTTATGGACTGCACAAGCGTGAGGGTCGAGCCCACCGAGGGCTGGCCCGATAAAATCTGTGTGCAATGCGTCCATGCAGTCAGTCGGAATCATGCATTTAAATCACTTGTGGAGCGCAGCGACAAAGAATTGCgcgaatatataaaaagcctGACGGTACGCCTCttggaggagcagcaacaaaaattggaACAACAAatactgcagcaacagcagcagctccaacagcaacaacaacagcagcagcagcaacaacaacaacagcagcagcagcagcaacaacaacagcaacaacagcagcagcagtcaccTATATATCttCCCAAGAGCAAATTGAAACCTCTGCAGCGTAAAGGTACCTCTCGACAGTCAAAGAAACAACAAGAGATGGTTCAGCTTCTGCCGGAACCggcgccaccaccgccgcctccACCACTGGTcacccagcagcaacaacaacagatacAACAAATTCAGCTGCCAACTCTGCAGCCGGCACCTGCGCAACTGATGCCAACAACGACGGCACAGCAAATTCTCTTGCCGAATGGACAGTTTATAACGACGCAAATTGTGACGCCGCAGCTGGCGCAAATTATCAGCCCGCAAACAACGGCATCGAATGCTACGGCGTCGGCACAAGCGCAATTTTTACCACAGTTGCTACAGGCGCCCAATGGCCAAACGTTACAAATTGTTCAGCAGCCGAATGGTACACAGACGTTGCAGCTAGTGCAGTTGGTGCCACAGCGAAGCATCGCCCCGGCGATTACAACGACTACTACAACGGACATGTGCACGACAAGCAGTGGAGCTTCGCTAGCCGATGCGGACGTCCAACTCTTGCACGATGGCGACATGGACGATGATGATCTGGACGAAGTCTACAATCACTTAGATGACAAGGGTCACACGTTTGAGACGATAGTACTGGACGATGATCAGCAGCAAGACTTTCTTAAGGACCAGCATCGGCAAGTGCTCATCGATGACGAATACACGCAAAGCGACACGCAGGAGCAGGAGGCCGACGAATACTTTGACGAGCAGCTGTTAGACCATGAGGATGGGGTCAAGCACgaggatgacgacgatgacaaCTTCATCATAGAGGAAATTCAATTAGATGAGGACGATATGCTGGACGATGCTGATGGAGAAGTAGATGGTGATGCAATGACAAATGTGGATGAATGCGAGTATATAACCGATGAACAGGATCACGGCCTCGGCGGCGATGTCGACGATGAGTTGCATTATGCTATTATGGAACCGACCGATGGTGATGTGAGCGCCAGTGACATGGATCAGACCTTCATAGATGTCgatccacagcagcagcaacagttacaggagcaacaacagcaacagcagtccGTGGACCTGCATAGTATATCCTTGGAAAATGCTGTGGTAGAGTTTGGACAGGACGCATTAGTCGCACCCACGTTACATGTCAGTAGCACGCCCAGTCCTACTCCCAGCTCAGCGAAACGTGCCCGTCGTGGCAACACGCAAGCGCAAACGCAGCTGGTCGAGACGCCTTGTAACCACCAGCATAGTCCACCTACCATAAGCAGTAAACTGGCAGCCGCCAATTCGCGGCAGCTAGTGCAAACTGCGTCAGtgatagcagcagcaggagctgatGATAATTACGAGATAGATGCAAATCTGGTCACGGAATTCATTAAGCAACACACATCACCTCTGGGTTCTGGACGATATATTTGTCACCTATGCAGCACGGAGTTCCGGCAGTTCAAGGGCCTCCAGAATCACATGCACTCGCACACCAATTGGATACGGGCCAATTGCAAAAAGCAGCCACAGTGTGAGATCTGCTTTAAGAGTTTCAAGGGGCCGGGCATGCTGCGCATGCACATGAAGACGCACGATGCTGAGACGAATACGCCGTTGTGCAACATCTGTAATCGCACGTTCAAGTCGAAGGCGATCCTctacaggcacagacagacgcatcAGCAGCGAGCATATTGCTGTGGCGTGGCGAATTGTCGCAAGAATTTCTCCAATGCGGCCAATCTGCGATGGCACGTAGAGCGCAAGCATCCGGAATGCGTTGAGCCACTCTACAAGTGCGGTGAATGCTCCACACTCTACGATCACATCGACAGTCTGCAACATCATGTAGAGAATACAGATCATGGCAGTAATGTCAGCGAAACGCAAACAATTATCACCACCAACTCCAACGCGGCGTTCAGCGGTGCCGTTAGCATTGTTAGCAATGGCACCGACATGTCCAGCATGATCGCCGCGGCACCAAATGCCCTAAGTGGCGCAACGGCAACAGGTGATACACATGCCGTTGTCGTGGGCTCATCCGGGGAGATGTATTTTGTGACGCAGGCGTAG
Protein Sequence: MMDRKKVLELDKICRLCISERKEMRPLFSEKVPEMLMDCTSVRVEPTEGWPDKICVQCVHAVSRNHAFKSLVERSDKELREYIKSLTVRLLEEQQQKLEQQILQQQQQLQQQQQQQQQQQQQQQQQQQQQQQQQQQQSPIYLPKSKLKPLQRKGTSRQSKKQQEMVQLLPEPAPPPPPPPLVTQQQQQQIQQIQLPTLQPAPAQLMPTTTAQQILLPNGQFITTQIVTPQLAQIISPQTTASNATASAQAQFLPQLLQAPNGQTLQIVQQPNGTQTLQLVQLVPQRSIAPAITTTTTTDMCTTSSGASLADADVQLLHDGDMDDDDLDEVYNHLDDKGHTFETIVLDDDQQQDFLKDQHRQVLIDDEYTQSDTQEQEADEYFDEQLLDHEDGVKHEDDDDDNFIIEEIQLDEDDMLDDADGEVDGDAMTNVDECEYITDEQDHGLGGDVDDELHYAIMEPTDGDVSASDMDQTFIDVDPQQQQQLQEQQQQQQSVDLHSISLENAVVEFGQDALVAPTLHVSSTPSPTPSSAKRARRGNTQAQTQLVETPCNHQHSPPTISSKLAAANSRQLVQTASVIAAAGADDNYEIDANLVTEFIKQHTSPLGSGRYICHLCSTEFRQFKGLQNHMHSHTNWIRANCKKQPQCEICFKSFKGPGMLRMHMKTHDAETNTPLCNICNRTFKSKAILYRHRQTHQQRAYCCGVANCRKNFSNAANLRWHVERKHPECVEPLYKCGECSTLYDHIDSLQHHVENTDHGSNVSETQTIITTNSNAAFSGAVSIVSNGTDMSSMIAAAPNALSGATATGDTHAVVVGSSGEMYFVTQA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00558268;
90% Identity: iTF_00544819;
80% Identity: -