Basic Information

Insect: Drosophila hydei
Gene Symbol: ci
Assembly: GCA_003285905.2
Location: NW:149365-159478[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.011 0.64 10.1 0.6 3 23 463 486 461 486 0.94

2 5 0.084 4.8 7.4 0.1 1 23 494 521 494 521 0.84

3 5 0.00015 0.0086 16.0 2.9 1 23 527 551 527 551 0.98

4 5 0.00027 0.015 15.2 0.4 1 23 557 582 557 582 0.97

5 5 1.1e-05 0.00063 19.6 0.3 1 23 588 613 588 613 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.011	0.64	10.1	0.6	3	23	463	486	461	486	0.94
2	5	0.084	4.8	7.4	0.1	1	23	494	521	494	521	0.84
3	5	0.00015	0.0086	16.0	2.9	1	23	527	551	527	551	0.98
4	5	0.00027	0.015	15.2	0.4	1	23	557	582	557	582	0.97
5	5	1.1e-05	0.00063	19.6	0.3	1	23	588	613	588	613	0.96

Sequence Information

Coding Sequence: atggatGCATATACATTACCAACATACTTTCCCCTAGCATATACGGAGCTACAGTTCTTAGCATCGAGgcgggcagctgctgcagctgcggcagcatcTGTACTACCATGTAGCTCACCTGtcagcaaccacagcaaccaGGTACCCACAACTGATGTAAGCAGCAGCTCGGTGCCAGTTGCTGTGTCTCCTGGAATGCCTGCGCCGCTGGCAGACTCCAGCCTGGCCTCTACTTTAGCACCGACTGCGAACGGTCAAAGTCTCGGCGGCGCTGCCCCCAGCggtcaccatcatcatcatcatcatcatcatgttCAGGGTCACAGTGTAGGTCAGCAGCATGATTTTCATCCGGCGTATAGAATCCCTAGCTACATGGAACAGTTCTATTCGTTGCAAAGAAGCAGCCCCACCGCCTCCTATCATGatccATATGCCAACTGTCCGCCAGCATTTCACTTAGCCGGATTGGGCTTGGGCTCCGGCGAGTATTTAAGTGCACGAGGAATGGGTTCCTTAAGCGAGCTGCATCACGCGgctgtcgcagcagcagcggctgctgcagcggcgggCTCTTTGGCCAGTACCGATTTTCATTTTAGTCTGGATGGCAATGGGCGTTTAAGCAGTCCACGTCCACCGGGCGGTGGCAGTATGCGCGCTAGTGTTAGCCGTAAGCGTGCGCTATCCTCATCGCCATACTCGGATTCATTCGATATCAATTCAATGATACGCTTCTCGCCTAACTCTTTGGCCACGATGGTTATGAATGGTTCGCGGGCGAGCAGCGCGGCCAGTGGCTCCTATGGCCATCTATCTGCCAGTGCCATCGGCCCCATAGCTCATACGCCTCATCTACAACAGCTGCAGGCCCATCTACTACGCGCTAGTGCCGGTCTTCTGCACCCCATGACCCCCCAGCaggctgcggcagcagcagctgccagctatTCCATGACTCATGCCGCTAGCGCTGCGGCGCTTGGCTTGACCGAGGTCTCCATTAAATCCAAGGAGCTGGCCAGCCAACCCACAACGCCAACCTCGACTCCGACAAGTGCAGCGGTAGCAGATGAATCCGCGATCAAGACAATCAGTTCGATTAAGAACTGTGACGAAGACAGCATGGATcggaaaaaaaacaacaatagcagcaacaagcttCTTGAACAACCATCATCTACATCGGAGAGTGTTGCTCAAGTTGAGGCAGATAGCGCGTCTGCAAATTTGTTGGAGCGACGACATCGTAATAAGACATTATGTATGGATCATCGGGCGCACATCCACGATGAAAATCCAGAGCATCCATTTAACGAATACGACTGCGCTACGGCGGATACAACGGACATTAAGGATGAGCCGGGCGACTTCATTGAGACAAATTGCCATTGGCGCAACTGCAGCGTTGAGTTCATCACCCAGGACGAACTTGTTAAGCACATTAACAATGATCACATCCAAAGCAATAAGAAGGCATTCGTATGTCGCTGGGTAGATTGCTCGCGTGGAGAAAAGCCATTCAAGGCACAATACATGCTTGTTGTCCACATGCGTCGCCATACGGGAGAAAAACCTCACAAATGCACGTTTGAAGGATGCTATAAGGCGTACTCTCGTTTGGAGAATTTGAAAACCCACTTACGCTCCCATACAGGTGAGAAGCCGTACACATGCGAGTATCCGGGCTGCAGCAAGGCTTTTAGCAATGCGAGCGATCGTGCAAAGCATCAAAATCGAACCCACAGTAATGAgAAACCGTATATCTGTAAGGCACCTGGCTGCACAAAGCGTTACACAGACCCCAGCTCTCTGCGGAAGCATGTGAAGACCGTGCATGGTGCCGAGTTCTATGCAAATAAGAAGCATAAGGGTTTGCCTCTCCATGATGCGAATTCCGGATTGGATAGGGAGAGGCGCAGAGACGGTCGGGATGGTaatcagcaacatcagcaacagcaggaacatcagcaacatcagcaactgcAAGAGCAGCATATTGACTCCAGTCCATGCAGTGATGATCTGCAAGGTGGCAAGCCAGTCAGTGTGTCCAGCCCGACCATTAAGTCGGAGTCCGATCCGAATTCACCTGGGCGAATGACTGCGCAAGCGGGATCCTCCACAGCGTCAGTTTCCGATTGTTTAATGCACATATACAGACAGGACGACCTAAACAGTCCTTCGGTGCCGACTCTCGACGAGTGTTGGCCCTATGACGATGATGTGGATGCAGTTGATCTTCCAATCGTGCTGCGTGCTATGGTTAATATGGGTAATGGAAATGGAGCACCATGTGCCAATCTAGCACGTCAACGTTTTCGTAGTCGTCTACAAACTAAGGTTATCAACTCGAGTAATTCAATGCTGTCTAACATACCGGAGagtaatcatcatcatcgggcCATTGGCATAATAGAGCTAAATCAGCGCATTACCGAGTTAAAAATGGAACCGGGCACATCGACCGTTACTCCACAGCCAATGCAATCGGGCCGGCTGTCCACGGGCAACTGCAACGGACTACAACTAACCGAGCTGCACAACCAGCCAATGCAAGGTCATAATCGAGCACAGGGACAGGGCACGAACCATCTTCTTCAGCAGGGTTACACTCAGGCGCAACAGCGCCGAGATAGCCAAAACTCGAATGCTAGCACATATTACTGTAGTATGCAGAGTCGACGTAGCAGCCAATCCTCACAGCTTTCATCGATGTCAACAATGAGGGCGTGTCCAGTATATAATACGGCATCAGGCACGCCGTCCCTGTACGATCCCATATCTCCAGGGTGCTCTCGTCGTTCCAGCCAAATTTCGAATGTGGTTACAGCGCAGCTTCCACAAATCCCAGCCAGCATTATGAACGATAACTCATCATCGGCACACGCCACATCGACTAATGCAGGCCAGCAATATATCGCAGCAAATGGATCTCGCAACAGCACCAGCCTGCCACCTCCGCCATCCTCTCATTTGATTGCCACACATTTGCAGCGCTTTCAATCGAACGATACGAATGGCCATTACCATAATAACAATGCGAATCCAAGTCAAAGTCAGTTAACAGTTGGTCAAAGTGGAGGACGCTTTTCTACACCAAACGTTTTGCAGTCGCCGCCGCTTAACTCAAAGTATCTCTATGACGAGCTAATTGGagttcatcatcatcacagACGTCAGTCAGAGCCGATTATGGCGCAGCTGAGCATAGAGCGAATGAGAAGTTCACCTACTTTCAATCCTCAAGTCTTCCATAACAACATAAATCGTGCCTCTTCCTCCACCACTAACACTGGCCATAAGGATTGCCCTGGCgaaataaagacaaaaacaacCGCTATAACCAATTCACGAGATCATCATcctaatgaaaaaattaatttggatGAAGTTGAAGAGCTTATTTTACCCGACGAGATGCTGCAGTATCTTAATTTGGTGAAGGAAACGGAGAAGCCCAAGGCGAAACCATTAACTGATGTTAATGACAAGGCTTCGTTTACGAACAGTTCGCAATATCTCGATTTGGTAGCGAATGCTGGCAATTCGCCCACACACGTGCCCAACTGTCCATCGCCATTTATGCAACAGTTGATGTCGCCTCAATCGGGTCATACGATGTCAGCGCTTGGAAGTCCATACTCCCAGCGAAACTACGAGCTAGAGGGCGGTAACAATAGTGCGTACCGTCAACAGCAACGATTGAATACTGAATCATCCTCACAGTATCCATATGCGCCAGGCCCAGCTCCGATTGCAGGTGCAGTTCCACTTCCTGCTCCAGCCCCCAGTCAGGCACATTCACTTCTACCATTCGGCTCGCTTAGTtgcgagcaacagcaacaaattgcatcgcatcaaaatcaaattattgaTTCATCGATGACCAGTCTGCCTGAACTATCAAATGTTGTTACTGTTATTCCAGTTGATCAAAAGCTTAATAATGTCAGCGAAATACAATGCGGGGTCGTCAGCCAATCGCAGCTGTCGCCAACAGCAAATATCACAGGGAATGGAAATACGAATGTCAATTGTCCCATCAGAattcagaatcagaatcagaatcagaaccCAGGTGCAGCGAAGCCCATTAGCGGACAAGCACAACATAAAATCCTGACGGACTACCAGACAAACAATATGGCATCGATGCATTCCGATACTTATCAGCGTACCCTAGAATATGTACAAAGCTGTCAAAACTGGATGGAGTCGAATAGTAGTACCTCGATGGGTAATGTTTCACTAAATACGCCAGCCACGCACAACAACCATCAACCCATTTGGCCCGACGTTAGTAGCTCGACGCACCCACATCCAAGTACAAATTTGATTATCAACGATATGACGACATCCTTGAGCTCTCTGCTGGAGGAGAATCGATATCTGCAAATGATGCAGTAG
Protein Sequence: MDAYTLPTYFPLAYTELQFLASRRAAAAAAAASVLPCSSPVSNHSNQVPTTDVSSSSVPVAVSPGMPAPLADSSLASTLAPTANGQSLGGAAPSGHHHHHHHHHVQGHSVGQQHDFHPAYRIPSYMEQFYSLQRSSPTASYHDPYANCPPAFHLAGLGLGSGEYLSARGMGSLSELHHAAVAAAAAAAAAGSLASTDFHFSLDGNGRLSSPRPPGGGSMRASVSRKRALSSSPYSDSFDINSMIRFSPNSLATMVMNGSRASSAASGSYGHLSASAIGPIAHTPHLQQLQAHLLRASAGLLHPMTPQQAAAAAAASYSMTHAASAAALGLTEVSIKSKELASQPTTPTSTPTSAAVADESAIKTISSIKNCDEDSMDRKKNNNSSNKLLEQPSSTSESVAQVEADSASANLLERRHRNKTLCMDHRAHIHDENPEHPFNEYDCATADTTDIKDEPGDFIETNCHWRNCSVEFITQDELVKHINNDHIQSNKKAFVCRWVDCSRGEKPFKAQYMLVVHMRRHTGEKPHKCTFEGCYKAYSRLENLKTHLRSHTGEKPYTCEYPGCSKAFSNASDRAKHQNRTHSNEKPYICKAPGCTKRYTDPSSLRKHVKTVHGAEFYANKKHKGLPLHDANSGLDRERRRDGRDGNQQHQQQQEHQQHQQLQEQHIDSSPCSDDLQGGKPVSVSSPTIKSESDPNSPGRMTAQAGSSTASVSDCLMHIYRQDDLNSPSVPTLDECWPYDDDVDAVDLPIVLRAMVNMGNGNGAPCANLARQRFRSRLQTKVINSSNSMLSNIPESNHHHRAIGIIELNQRITELKMEPGTSTVTPQPMQSGRLSTGNCNGLQLTELHNQPMQGHNRAQGQGTNHLLQQGYTQAQQRRDSQNSNASTYYCSMQSRRSSQSSQLSSMSTMRACPVYNTASGTPSLYDPISPGCSRRSSQISNVVTAQLPQIPASIMNDNSSSAHATSTNAGQQYIAANGSRNSTSLPPPPSSHLIATHLQRFQSNDTNGHYHNNNANPSQSQLTVGQSGGRFSTPNVLQSPPLNSKYLYDELIGVHHHHRRQSEPIMAQLSIERMRSSPTFNPQVFHNNINRASSSTTNTGHKDCPGEIKTKTTAITNSRDHHPNEKINLDEVEELILPDEMLQYLNLVKETEKPKAKPLTDVNDKASFTNSSQYLDLVANAGNSPTHVPNCPSPFMQQLMSPQSGHTMSALGSPYSQRNYELEGGNNSAYRQQQRLNTESSSQYPYAPGPAPIAGAVPLPAPAPSQAHSLLPFGSLSCEQQQQIASHQNQIIDSSMTSLPELSNVVTVIPVDQKLNNVSEIQCGVVSQSQLSPTANITGNGNTNVNCPIRIQNQNQNQNPGAAKPISGQAQHKILTDYQTNNMASMHSDTYQRTLEYVQSCQNWMESNSSTSMGNVSLNTPATHNNHQPIWPDVSSSTHPHPSTNLIINDMTTSLSSLLEENRYLQMMQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00544781;
90% Identity: iTF_00502812;
80% Identity: -