Basic Information

Insect: Drosophila hydei
Gene Symbol: ZNF541
Assembly: GCA_003285905.2
Location: NW:1126669-1154580[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.00012 0.0067 16.4 0.2 2 23 353 374 352 374 0.97

2 5 3.6e-06 0.00021 21.1 1.3 1 23 380 402 380 402 0.98

3 5 0.00035 0.02 14.9 2.5 1 23 408 432 408 433 0.94

4 5 0.0006 0.034 14.1 0.8 2 23 705 726 704 726 0.97

5 5 0.0017 0.095 12.8 0.1 1 23 1837 1861 1837 1861 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.00012	0.0067	16.4	0.2	2	23	353	374	352	374	0.97
2	5	3.6e-06	0.00021	21.1	1.3	1	23	380	402	380	402	0.98
3	5	0.00035	0.02	14.9	2.5	1	23	408	432	408	433	0.94
4	5	0.0006	0.034	14.1	0.8	2	23	705	726	704	726	0.97
5	5	0.0017	0.095	12.8	0.1	1	23	1837	1861	1837	1861	0.98

Sequence Information

Coding Sequence: ATGGCTGCCATAAATACGGTACCTAAGAGCATACACCTGCCTTTGACGAATCTCAGCGCATCGCGCGTGTTGATGTGCAACGCATCTGTGGGCAGCGAGGGTTCCGTAACACTGCAACTGAGAGATGCGAATGCTTTGGAGGCAGCCGccagcagcacagcaacagcaacaacaacaacagcagcgacatcGTCACCAGGCCAAGCAAATGCGTCAGGACTAACGTCAGCATTGGAGAATGCGCTCACTATTGGCTATCCGGATCCGGATATGTTAGCAGATGTCTTGGGCACCATTCAGACAGCCTCTCTTAAGAACagacaaagcaacaacaacaacagcaatagcaacagcaatagcaacagcaacagcaacaacaactgcaacagcaacaccaaaaGAAGCAttaatggcagcagcagccgaatcAGCACTGCGCCAACAATTCTGAACAATACGATAACGAGCTCTGGCGTTCGCCTGAACAGTCCCAACAGGATAACAATAACGCGACGCAGTGCTAGCAACAAGATTAGCGTACAAACTGTGAGCGCCTCGACTAATACAACCATTAGCAGCATTGGTGGCAGCAAGACCAACTACATCAAGAACTGTCTaatacgcagcagcagctgcagcaacacgGCCACCAATGTCACAACGCTGGCACAGATtatgagcaacagcagcaccagcagcgccGCCAGTTTACTCAGTCAacacaacaataatagcaactgcagcaacagcagcaacttcaGCAGCGCCTCTTCTGTGGGCAGCAGCATTAGCAtaagcagcaccaccagcagcagcaccaccagcagtcacagtcacagtagtagcaacagcaacagcaacagcaacagcaacgacagcaacagcagcagcggtcaCAGCCTAAGTTTCAAGAGCAACGGCCGACATGTTGCTGGCAtagtaacaacagcagcatccacGAACACCACTGCAACTGGCATTGGCATTATCACTGTCGACCACGCTCCCCGCAAGAGCCGCCCTAAATTAACCTCGCCCACACGCCACGGCCCCCAACAGTGTCAGaTTTGTAGCAAGATCTTTGGAAATGCCTCGGCATTAGCCAAGCACAAACTGACGCACAGCGACGAACGGAAATATATTTGTGCGCTCTGCTCGAAGGCATTCAAGCGGCAAGATCACTTAAACGGACACATGATGACGCATCGGAACAAGAAACCTTACGAGTGTAAGGCAGAAGGCTGCGGCAAGTCCTATTGCGATGCTCGCTCCCTTCGCCGGCATTCGGAGAATCACCATGGCGGCGTGGCCACTCCGAACAACAACTCGCTCTCGCCCACGACTAGCAGCAACTGCGGCAGCgtcagcagtggcagcagtagcagcagcagcagcgtgggcgtggccagcaaCTCGCTCAGCCTGTCGCCGGCTACGGCGAGTGGAGATGCCAGCTCGCCAGACGGTGCCACCTGCATTCGCACCTACATTTCCACGGGCAGCACTGTGGTGGACGCAGCCACGGGCATTGCGTTGTCCGACGAGCAGATCAAGGCCATGAATTTGCCCATTAAAACTGGGGTTACTTTGCTCTCGCCCACCACATCAACATCGTCGAACGCATCGTCTACAGCCTCCTCGTCCTGCTCTAACacaggcagcggcaacggcaacggcaacggcagcggcaacggcaacagcaacggcaatggcaatggcaatgccatTGTCACCAGCTCACCGACAATTACGCTTAGCGACGGCACTACGCTCGAGGGCGATGGACTGACGCGCGAGCAACTCGATCTCATAAGCAAGATCATGCAGCAGACAAAGCAGACCAGTGCACAGGTCACCGTCTCCTCTCCCACCAGCGTCAGCTCCTATAAAATCAATACAGAGACAGCGCAAGTTTCGTCGCGCCCACGCACCTGGAATATGCAATTGCTCAACAACGCACAAAATGTGACTGTAACTGTGGAGGATGGCACAGAGGTAGCCGGATCGGCATCAACTTCAACCGACGAGGTCAAGGACGATGAGTTGAGCCAGCAGCTGGTGGCAGCCATCAATCCCCATCTGCTCAACATTGTTAAGATCGACAAGCCGGTGGAGTGCAACCTGTGCCATCGTAAGTTTAAAAACATACCCGCCCTCAATGGGCACATGCGTCTGCATGGCGGATACTTCAAAAAGGATCCAGAAACCAAGCGCACCGAGAAAAAGGACTCGAACGGACCTCCCTTACAGACCGCCAGCATAGGAGTGCGCGCCCTCATCGAGGAGAAAATCATAAGCAAACGGAAGGACATAAATAAGGGCGCCTTCGTAGTGCCTGCACCACCAAGCACCACGTGCAACAGCGTTGGagtctgcagcagcaacagcaacacactgAGACGCTCGATAAGCGACCTGGAGAGTTTCCTCAACCCGAAATGCAGCACCACCAGCCTGAGTCAAGCActgtccagcagcagcagcaccaccacagCGGTATTGCCGGCAGCAACCACAATCAAGAGCAGCAACGGGCTAAGTATACAGCAGATTGGACTGCCGCAAAGCATCGAAATCTTCAGCGGAGGCCACAGGCAGCCGAAAACCCTCAGTCTAGGCAGTGGTGCCAACACCATAACCATAACCACCAACAATGTGCCTACCACAACCACCATGAGCGCCCTGACGGCATTGAAGGGCGGCGGCACCATCAATGGCATCTCCAGCAATGTGGATCCCAAGGACTCGACATTAATTGAGCTGCTCAAGCGCGGAACGCGCATTGCCGTCGCGTCGAAGAAGACGCAGAGCAGCGCGAATCTGTTGCTGAGCAACGTGACGGGCACGGAGCTGACAGCTATCGGCAGCAGCGTCCAGACCACTGGTCGACAGATAATCACCAACAACAATCGCACCGTCATCATACCCTCAGATGTCCATGTGGTGTCCACCAAGAGCAAGCTCATTTCGAGCCAGGCCATCACAGCCAgcgacaacggcagcagcaacaataacaatgcaaCATGTTCTGCGAGCAGCATCTCGTTGCCGGATGGCACTCCGCTCTCGGTGGCCATTGCGAATAGCCAGGAAAATCTGGGCGTGAGTGAGGCAAGCACCATTACGGCCGGCGGCGGCGTTTATACGGTGACCTACACTAGCGATGCGGATGCGTCGGACCTCTTCGACGACACTGAGGTATACAATGTCTCGGACACCGAAATGCTGCTCCAAACAGTGGACACTATGGAATTACTCAATGATGACGAGGAGGCGGTGCACAAGAGCGAACATTCCGAGGACTTTGCGCTGCTCAGCGAGACCGGAGAAACTGTTCATACGCAGCTGGTCAAAATGGAGCCGGGACTAACCAGCACGACTAACACCATGAATAAGACGACGCCGTTGCCCACCTTCCAGCAATTCCATTCCAAAGAGATTATCATGCAGAACAGCTCACAAATTCAGGCCATTGCCAGCATGCGTAGCGGAAGCAATCTGGGCGTGCTCGCCTCTCCCCTGCATTCGCCGATAGCCTATCCGACGCCGCCGTCCAGCCACGAGAATATGGCCCAATCGTCGCCTTTCATAGAGGACGCTGCGGCTCAGTTCGTGGACGCCAGTCACACGTTCTTCGGCGACAAGACGGACTTCTCGCATGTATATTTTAAGACAGACGACGGCGAGTCCATGCAGCAGCTCACTGAGAACGACAACGAGAAGATACTCAAACTGAAGACGGTGCTCGAGGAAAGCAGCTTCGGCCAGTCCATCAAAGTGGAGGATCTGCTAAGCAGCACTGAAGATGATGCTGAATGCGACTTGCGTGAGTTTGCCGAGACGAATCTCTCGTTCCTGGACGAGGATCAGGAGTTCCTCAATGATTCACGAAACGCTACCTCCCCGCTGTCCGAGTCTTTCTTCACCAGCGGCATTGGCTCGGCCGAGGATGTTAAACAAGTGCTGCGAGAGGTGCTGCCCGAGGAAAATATACAATTGCAGTTGAGTAGCGAGCAGCAGGGCGAGAACATCATTGATCTGTACTATTTGCCGGGTCTGGGCCTGCAATCCCAAATGATGCCCAACTCCGATGATCCGCTTTTGTCGTCCTCGCCACGCGAATTCGGCCAGCAACGTCAGGTTGTGCACACAAGCacagctgcaactgcgacCGTGCAGCCTATCGAACAGTTGCAGTCCACGACTGTGCTTTAcgaccaacagcaacagcagcagcagcagcagcaacaattacagctgcaattgcaaatgcagtcccagcagcagcagcagcagcagccacaggagcagcagcaatcacaAGAAGAGCAACAGCTGGGaactcagcagcaacagctgcaattgcCACAGCTACCTGCAGTTCAAGGTGAACagccccaacagcagcaacagacagATTTTATGCTCAGCAACTTTACGCCCGTGAACTGTCAAGCCCAATATATGGATGGCAATCAGCAGCCGATGATGCTGCAGCCGCTGAACAGTCTGCTGCAGCCAATGCTttacggcagcaacagcgctgCCAGCAATAAGCATGCATTTAGCACGCTTCTCGGCTCCAATACGGTTCAGGCAACTGCACTTGATGCGAGCCTGCTCTTCGCCTGCGACGACACAAAAAATAGCTGCAACAAGCCCATGTTAGCCGGCTTATCCGCAGCCATTCCGACGCCGGTAGTTACGGCTGCGCCAAGTGTTGCGAACCTGCAGCCGTTGTCCAATCAGACGAACTCCATACTGAAGCGTCGCCTGCGGTCGAACGGAGCGCAGGATGTGCACAAGTTTTCGAAATTCCATACGCTATCGCCGCACCGCTCAAAGCTGCGCAAGCCATCCCGGACCCACTATACCCCTGCTCCGATACTCAATCCGGATCGCAAGGGCACCGGGCTCTACTGCAATGTGCGCAAGCAGCTTGGCCAGGGAATGTTCGACGTTTTCGACGATGACTTTGGCGATCCTGTGGGCTTGGTGGACTTCTGCGATGAGTCCAAGGTGAACCTTGGCTCCACCTATCAAGCGCAGATCCCAGCCTGCAAGCCACCAGACGAAGCCATCAAGGAGCCCATGTGCGCCGACCTAATGTGGGATCCAAGCGTCCAGCTAGACGATAAGATACTGATGCGTTACATAGATCTCAGCAAATCATCGGCCGTACCCATGGGCAGCCATTCCGAGGAGGTGGCCCTGCAAACGCTGCTCGACGCAAAAGGCAACTCCGCGGCAGCGGTGCTTACCCTACTGCAGATGCAGTCCAGCGCATTCCAAATGAAATGGACTGCCTACGAGCTAGAGCAGTTCCTGCGCGGCCTCGAGAAACACGGCAAGGACTTTGGCAAAATCGCTAGTGAGCTTCACACGAAGACATCCGGGGAATGCGTGcaaatgtattatttttggAAGAAACTATGTGTGGACTACAAGGTATCGCACCTCAAAATGGAGCCAGTTCCTGCAAGCATCCCCATGGTGGAGCAGAAGCCCTACGTTTGCGAAATTGCCGACTGTTCGGCGAGCTTCAGTTCCAAGGCGGCGCTGCATGGTCATGTTCGCATACACGCTTATGGTagaaatgccagcaacaataatagtaacaacaacaacaacagcaacagcaacatccaGCATGCCACGGCAACTAGtgccaacaacagccacaattccagcaacaacaacagcagcaacaacaacaccaatagCAGCAACGCATGCATACCCCTGACTGGCAGCAGTCAACAGActagcaacaaccacaacagcaatgcaacagcaaccatAACGCACACTAATGGCAATAACAACACCAccgcgaacaacaacaatattatgaacaacaacaacagcatcgcTGGCATTTCCACAAACCCAACGATGCtttcaatagcaacaacagcaatagcgacagccgctgcaacagctgttgctgcggctgcggccgCATCATCCACAGCATCGACAGCAACGAAAgacagtagcaacagcaacaattccAATATACCCAAGGACAGTGAATTTCCCTGCAAGGTGTGCGGCAACGAAGAGTCACAACTCGCAAATAGGCGTTACTGA
Protein Sequence: MAAINTVPKSIHLPLTNLSASRVLMCNASVGSEGSVTLQLRDANALEAAASSTATATTTTAATSSPGQANASGLTSALENALTIGYPDPDMLADVLGTIQTASLKNRQSNNNNSNSNSNSNSNSNNNCNSNTKRSINGSSSRISTAPTILNNTITSSGVRLNSPNRITITRRSASNKISVQTVSASTNTTISSIGGSKTNYIKNCLIRSSSCSNTATNVTTLAQIMSNSSTSSAASLLSQHNNNSNCSNSSNFSSASSVGSSISISSTTSSSTTSSHSHSSSNSNSNSNSNDSNSSSGHSLSFKSNGRHVAGIVTTAASTNTTATGIGIITVDHAPRKSRPKLTSPTRHGPQQCQICSKIFGNASALAKHKLTHSDERKYICALCSKAFKRQDHLNGHMMTHRNKKPYECKAEGCGKSYCDARSLRRHSENHHGGVATPNNNSLSPTTSSNCGSVSSGSSSSSSSVGVASNSLSLSPATASGDASSPDGATCIRTYISTGSTVVDAATGIALSDEQIKAMNLPIKTGVTLLSPTTSTSSNASSTASSSCSNTGSGNGNGNGSGNGNSNGNGNGNAIVTSSPTITLSDGTTLEGDGLTREQLDLISKIMQQTKQTSAQVTVSSPTSVSSYKINTETAQVSSRPRTWNMQLLNNAQNVTVTVEDGTEVAGSASTSTDEVKDDELSQQLVAAINPHLLNIVKIDKPVECNLCHRKFKNIPALNGHMRLHGGYFKKDPETKRTEKKDSNGPPLQTASIGVRALIEEKIISKRKDINKGAFVVPAPPSTTCNSVGVCSSNSNTLRRSISDLESFLNPKCSTTSLSQALSSSSSTTTAVLPAATTIKSSNGLSIQQIGLPQSIEIFSGGHRQPKTLSLGSGANTITITTNNVPTTTTMSALTALKGGGTINGISSNVDPKDSTLIELLKRGTRIAVASKKTQSSANLLLSNVTGTELTAIGSSVQTTGRQIITNNNRTVIIPSDVHVVSTKSKLISSQAITASDNGSSNNNNATCSASSISLPDGTPLSVAIANSQENLGVSEASTITAGGGVYTVTYTSDADASDLFDDTEVYNVSDTEMLLQTVDTMELLNDDEEAVHKSEHSEDFALLSETGETVHTQLVKMEPGLTSTTNTMNKTTPLPTFQQFHSKEIIMQNSSQIQAIASMRSGSNLGVLASPLHSPIAYPTPPSSHENMAQSSPFIEDAAAQFVDASHTFFGDKTDFSHVYFKTDDGESMQQLTENDNEKILKLKTVLEESSFGQSIKVEDLLSSTEDDAECDLREFAETNLSFLDEDQEFLNDSRNATSPLSESFFTSGIGSAEDVKQVLREVLPEENIQLQLSSEQQGENIIDLYYLPGLGLQSQMMPNSDDPLLSSSPREFGQQRQVVHTSTAATATVQPIEQLQSTTVLYDQQQQQQQQQQQLQLQLQMQSQQQQQQQPQEQQQSQEEQQLGTQQQQLQLPQLPAVQGEQPQQQQQTDFMLSNFTPVNCQAQYMDGNQQPMMLQPLNSLLQPMLYGSNSAASNKHAFSTLLGSNTVQATALDASLLFACDDTKNSCNKPMLAGLSAAIPTPVVTAAPSVANLQPLSNQTNSILKRRLRSNGAQDVHKFSKFHTLSPHRSKLRKPSRTHYTPAPILNPDRKGTGLYCNVRKQLGQGMFDVFDDDFGDPVGLVDFCDESKVNLGSTYQAQIPACKPPDEAIKEPMCADLMWDPSVQLDDKILMRYIDLSKSSAVPMGSHSEEVALQTLLDAKGNSAAAVLTLLQMQSSAFQMKWTAYELEQFLRGLEKHGKDFGKIASELHTKTSGECVQMYYFWKKLCVDYKVSHLKMEPVPASIPMVEQKPYVCEIADCSASFSSKAALHGHVRIHAYGRNASNNNSNNNNNSNSNIQHATATSANNSHNSSNNNSSNNNTNSSNACIPLTGSSQQTSNNHNSNATATITHTNGNNNTTANNNNIMNNNNSIAGISTNPTMLSIATTAIATAAATAVAAAAAASSTASTATKDSSNSNNSNIPKDSEFPCKVCGNEESQLANRRY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00573254;
90% Identity: iTF_00519855;
80% Identity: iTF_00519855;