Basic Information

Insect: Drosophila hydei
Gene Symbol: -
Assembly: GCA_003285905.2
Location: NW:1443571-1445950[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 2.5e-05 0.0014 18.5 2.5 1 23 411 433 411 433 0.97

2 7 2e-05 0.0011 18.8 0.2 1 23 439 462 439 462 0.97

3 7 0.09 5.1 7.3 1.7 1 23 468 491 468 491 0.93

4 7 1.5e-05 0.00087 19.2 2.4 1 23 531 553 531 553 0.96

5 7 0.00021 0.012 15.6 1.4 1 23 559 581 559 581 0.98

6 7 0.00014 0.0082 16.1 0.4 1 23 587 609 587 609 0.98

7 7 0.0036 0.21 11.7 5.1 1 22 615 636 615 639 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	2.5e-05	0.0014	18.5	2.5	1	23	411	433	411	433	0.97
2	7	2e-05	0.0011	18.8	0.2	1	23	439	462	439	462	0.97
3	7	0.09	5.1	7.3	1.7	1	23	468	491	468	491	0.93
4	7	1.5e-05	0.00087	19.2	2.4	1	23	531	553	531	553	0.96
5	7	0.00021	0.012	15.6	1.4	1	23	559	581	559	581	0.98
6	7	0.00014	0.0082	16.1	0.4	1	23	587	609	587	609	0.98
7	7	0.0036	0.21	11.7	5.1	1	22	615	636	615	639	0.91

Sequence Information

Coding Sequence: atGAAGTGTGCAGTGCAAAACTGTGCAAACAAGTTCAGATCAAGACAAAAACACTCGCAACAATTAAGTTTCTTCAGCTTTCCCAAAAACCCGGACGTCTTAAAAAAATGGCTTTCATTTTGTCGCAGatacaacaaagaaaaactaaagGCACCACTCAAGAGCGTCATTTGTAATGAGCATTTTAAAGAGGAGGATATTCAAGGAGCATTGCAGTTTCAAATGGgCCTATGCAGCAAAAGAACGCTGAGACCGGGCGCCGTGCcatgcataaacaaaaacgaCGTGAGTGCAGTTGAACGAGAGCGATCTGAAAggcgtaaaaacaaaaagctggTCGCAGAGCTACTAGAGGAAGCGGCAGCGCGTGAAGCAGCCGAAGCCAGCGGAGCAATTGTTATAGCGCCAGACTTTATCAGAAACACAGGCATTGTCTCGGTACCCGACTTCGTTAATGCTACAGGCAATGCTTTCACTCCATGTACACCGACACCCAGTGAAAGCGATCCCTTGGCTGAGGAGCAGGCTGAGCTTGAGTTGAGcagaaatgaaaaagttattgAGCAGATTAAGTGTCGCACCTGCTATGAgacatttgttgttgatgaaaATGCTAAAGACCTTTGTGATGAACAAAACGCTGTCATGTTATTTCACATTGAAGTCATAACCGGTATCTGGATCCAATGTAGCGAAGGAGTCTCGCCGTTCATGTGTTCAACCTGCGTCCATAATCTGCGCACAGCCATTAATTTTCGAGAAACATGTATTCGAACGGAGGTAGAACTTGCAGGAGATACGATTATTAAGGAGAACGACACAGACGCTTGGAATGCTAATGATTCAGAGATAGTGCAGATTAGCGAGAATAGTGTTAAAGATTATGTTACCATATTTCCGGCAGAAGATCAAAATGGTCAAACAACTGTCGTTGAACCTATGCCTTTGCCTCTGGAAACAGCACAGCAAATTATTCAGCCAGTATATACATCGGCTGCAGACTCAAATAGTATTGCATTGGGAGCTCAGATTTATGAAGATCTTCTTAATGAATACAGGGGTAAGGATAGAATAGCACGTCCACGACAAAGGAAGGTAACAATAACCAGGACAAAAGTGGTAAGAAAACGCAAACGGAAACCTCGGGATCCTAAACCGAAAAGACCGAAACGCACAAAAGAGGAAAGAAATCGAATACGTCGTGAGCAAATCAGAGCCATGCCCTTGAATCATGTGTGCGATCAGTGCGGCGCCTCATTTCGGGTGAGATGTAATTTAACGATCCATATGCTAAGGCATACGCGCACAAAGAACTATCCTTGTCCCGAATGCCCTAAAAAATTCTACGATGCCTATATGCGAAACATTCATATACGAGTACGGCACAGAGGCGAATTGCcatttgaatgcaatttcTGTAGGAAAGCATTTGGTTCTTCCAATACGCGGTATCTGCACGAAAAAAAAGTTCACGGAGCATCTCCACGCATTCACCGAAACTTGAATAGATTGAATAAAAGAATCGAGCTTAAAAATGAGCAGCAGGACCATCAACAGGAGGATGGACTGGGACAAAAGGAAAATGTCCGCCATTTTTGTTCATATTGCAATAAGAGCTACGCAACAAAATATGCACTTAATTGGCATACCAATATTCACTTGGGAGTCACgccatttaaatgcaaactCTGCGACATGAGCTTTGCAGATCCTCAATCGAAAAAGAAGCACGAAATGAAGCATGATAGTAAACGTCCCTTCGAGTGCGATATTTGTCTTAAGGGGTTCTATGTGCGCAGCAAGCTGAAGGAACATGAACGTATTCACACTGGCGAACGACCCTATAGatgTGATGTTTGCAACGCCTTCTTTCGATACAAGTTCAATTTGTGTTCGCATCAATTTAGCAAGATGCATAAAGAAAATCTACAAAAGCTAGCAAAGGTTGAAGTGATCGAAGATTCAAATTAA
Protein Sequence: MKCAVQNCANKFRSRQKHSQQLSFFSFPKNPDVLKKWLSFCRRYNKEKLKAPLKSVICNEHFKEEDIQGALQFQMGLCSKRTLRPGAVPCINKNDVSAVERERSERRKNKKLVAELLEEAAAREAAEASGAIVIAPDFIRNTGIVSVPDFVNATGNAFTPCTPTPSESDPLAEEQAELELSRNEKVIEQIKCRTCYETFVVDENAKDLCDEQNAVMLFHIEVITGIWIQCSEGVSPFMCSTCVHNLRTAINFRETCIRTEVELAGDTIIKENDTDAWNANDSEIVQISENSVKDYVTIFPAEDQNGQTTVVEPMPLPLETAQQIIQPVYTSAADSNSIALGAQIYEDLLNEYRGKDRIARPRQRKVTITRTKVVRKRKRKPRDPKPKRPKRTKEERNRIRREQIRAMPLNHVCDQCGASFRVRCNLTIHMLRHTRTKNYPCPECPKKFYDAYMRNIHIRVRHRGELPFECNFCRKAFGSSNTRYLHEKKVHGASPRIHRNLNRLNKRIELKNEQQDHQQEDGLGQKENVRHFCSYCNKSYATKYALNWHTNIHLGVTPFKCKLCDMSFADPQSKKKHEMKHDSKRPFECDICLKGFYVRSKLKEHERIHTGERPYRCDVCNAFFRYKFNLCSHQFSKMHKENLQKLAKVEVIEDSN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00506143;
90% Identity: iTF_00519953;
80% Identity: iTF_00519953;