Basic Information

Insect: Drosophila hydei
Gene Symbol: L
Assembly: GCA_003285905.2
Location: NW:1882565-1891054[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 8.6e-06 0.00049 19.9 2.9 1 23 141 163 141 163 0.98

2 17 0.3 17 5.7 6.2 1 23 169 191 169 191 0.97

3 17 1.4e-07 8.2e-06 25.5 3.2 1 23 197 219 197 219 0.99

4 17 1.1e-05 0.0006 19.7 0.4 1 23 225 247 225 247 0.99

5 17 0.012 0.67 10.1 0.2 2 23 326 350 325 350 0.93

6 17 0.00026 0.015 15.3 0.2 2 23 376 398 375 398 0.96

7 17 0.052 3 8.0 0.7 1 23 462 484 462 484 0.97

8 17 0.061 3.5 7.8 0.3 2 23 492 513 491 513 0.91

9 17 0.017 1 9.5 1.2 3 23 524 546 521 546 0.86

10 17 2.8 1.6e+02 2.6 1.0 2 23 582 604 581 604 0.95

11 17 0.0022 0.12 12.4 1.1 1 23 647 670 647 670 0.97

12 17 0.0054 0.31 11.1 1.6 2 23 842 864 841 864 0.96

13 17 0.097 5.5 7.2 0.1 1 23 870 892 870 892 0.92

14 17 0.47 27 5.1 0.4 2 23 900 921 899 921 0.93

15 17 0.26 15 5.8 1.3 1 23 1020 1042 1020 1042 0.94

16 17 0.017 0.96 9.6 0.0 1 23 1052 1074 1052 1074 0.96

17 17 0.00019 0.011 15.7 1.2 1 23 1079 1101 1079 1101 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	8.6e-06	0.00049	19.9	2.9	1	23	141	163	141	163	0.98
2	17	0.3	17	5.7	6.2	1	23	169	191	169	191	0.97
3	17	1.4e-07	8.2e-06	25.5	3.2	1	23	197	219	197	219	0.99
4	17	1.1e-05	0.0006	19.7	0.4	1	23	225	247	225	247	0.99
5	17	0.012	0.67	10.1	0.2	2	23	326	350	325	350	0.93
6	17	0.00026	0.015	15.3	0.2	2	23	376	398	375	398	0.96
7	17	0.052	3	8.0	0.7	1	23	462	484	462	484	0.97
8	17	0.061	3.5	7.8	0.3	2	23	492	513	491	513	0.91
9	17	0.017	1	9.5	1.2	3	23	524	546	521	546	0.86
10	17	2.8	1.6e+02	2.6	1.0	2	23	582	604	581	604	0.95
11	17	0.0022	0.12	12.4	1.1	1	23	647	670	647	670	0.97
12	17	0.0054	0.31	11.1	1.6	2	23	842	864	841	864	0.96
13	17	0.097	5.5	7.2	0.1	1	23	870	892	870	892	0.92
14	17	0.47	27	5.1	0.4	2	23	900	921	899	921	0.93
15	17	0.26	15	5.8	1.3	1	23	1020	1042	1020	1042	0.94
16	17	0.017	0.96	9.6	0.0	1	23	1052	1074	1052	1074	0.96
17	17	0.00019	0.011	15.7	1.2	1	23	1079	1101	1079	1101	0.97

Sequence Information

Coding Sequence: ATGGATGCTTTTTGTCTTACAGATATGTACAGCACGCACACTTCATCGAGCTACTCGCCCAGCATCTCGGATGGCACTTTGACGCCCAactcccagcagcagcagcagcagcagcagcagtcgtcgcagcagccacagccacaggcagGCGAGGAGCCCGGCGAGGAGGCCAAGGCGAACGGCGATGCTGCACAGCAAACGGAACTGGAGCAGGAGTTGAGCAAGCCGAAGCGACCGGCACActtgcatcatcatcatcatcatcattatcatcatcagcaggcGCTGAAACTGGCGAACAAGCTGCGCAAAATCAATAAGGATGCAAAACTGGCTgcaggacaaggacaaggacatgGCACAGCCGCCAAGTTTGATAAGTTGACAGGGGAGGGGATTAAAAGTCGCGGCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGACTCGGCTACTTGAAGCATCACGTGCAGaGCCATGCCGAACACTTGCCTTTCAAGTGCGAATACTGCGCGAAGCTCTTCAAGCACAAGCGCTCGCGAGATCGCCACAAGAAGCTGCATACAAATGAGAGGAACTACAAGTGTCCGCATTGCGAGGCTGCTTTCTCCAGAAGCGATCATTTGAAGATTCACATGAAGACACACGACATCCAGAAGCCCTTCCAGTGCAGCATGTGCAATCGTGGCTACAACACGGCCGCCGCCCTGACCTCCCACATGCAGAAGCACAAGAAGAACGCCGCGATACTGGCAGCTGGCGGCAATCCCAATGCGCTCAACTATAGTCCGCGGTCCACGGGCTCTGCCTCGATATCGAGCAATGGCAGCTTGCACAAGCGTCGCTATGCCTTGGCGCTGGCCTCCGACAGCAGTCCCAGCCGGCTGGAGTTTCCGAAGCGGGCGCGTGGACAGCTAACGAGCACGCCCACGGCCACAACgatagccacgcccacgccgctgctgcgctgcaGCTACTGTCCCAAGGCAACGGAGTTCAGCAGTCTCGAGCAGCTAAATGCGCATCTGCAGAGCAcacacgagcagcagcagcagcagcagcagcagcagcagcagcaaaaggatGCGGATGGCCAGACGAATGGCTTTCAATTGAGCTGCGAATATTGCACGATGAAGTTTGTGAACATCGCGGCGCTGTTCCAGCACATGAGAGTGACGCACTTGGATCGGCTCAGCAGTCCCAATGCCTATTACGAGCAGTTCAATCGCCTCGGCTCGCCGCAGTCGAAGGTCAAGTCGGATTTGGCGGCGTCGGAGAAGCCCGAACAGGAGCTGCCCACCGACTTGAGCAGCAATAAGCGACGTCCTCTGACATCGCCCacacagcagccgccgccgccgccgggCATCTTCTTTTGCAATCAGTGCAACGCTGGGCTGCCGGACTTCGAGAGCTTCCGGAACCATCTGAAGAGTCACATAGCCGAGGGCATGCAGCTGATCTGTCCGCATTGCGGGCTGAGTCTGCCCGAGCAGTGCGAATACGAGCGCCACGTGGTTGCCCACTTTTTGATCAGCAGCTCGGAGTTCAATTGCTGCAGCGCCAGCTGCGGCAAGTCCTACGCCAAGGCCGAGGAGCTGCATCAGCATCTGCTGGCCGAGCACGTGCAGACCATGCTCAAGTGTGTGCTCTGCTCAGAGCTGTGCGAGAACCGCATGTCGATGCAGCTGCATCTGGCCTGTGCGCACAGTCAGGAGTCGAAGCTGCTGCGGTGCAGCGCCTGCCTGGAGCTCTTCCGCAACGATGCCGACTTCCATGTGCATGTCAAGACGCGCCACCAGCTGGGCAATCAGGGCCTGGGCAATCCGCCAGCGCCGGCCAATCCCTTGCAGTGCATGTTCTGTCGCGCCGTCTGCTCATCGGAGCTGGAGATGCACTTCCACTTGGCGGCGCATGCGCGACAATTCCGCTGCCCCAGCTGCCCGGAAACGTTTCACGTGGAATTCCTGCTGGACCGGCACATGCAGAGCCAGCACGGTGGCATCAAGGACAAGGAGTCGCCTGTGGCTGGCAACATGGGCAGCTTGTATGTGAATGCATTGCTGCCGCCTCTGGCTgcggccgctgcagctgctgccgcagcaaacaatgccaacaacaacaacaacaacaacaacaatagcaacctGCACATAGACTACAACGTCGCCTTCAAGGGCTTGTTCGGCGGCAACAACCCGCCGAGCAAGTTCTACAACAGCCCGCTGCAAGTGGACACCAAGCAAGCGCCGCACCCAGCCCTGATGTACGGCCTGAGCCAGCGCTATTTGATGGAAATGTACGCGGCGAAGGCCAATTCGCCGGCCAATGCCAGTGCCGCCGAGCTGCCCACGCCTCAGGCTGTGCaagcggcgacggcggcgagtgccagcagcagcagcaacaacagctacagctgcggCATGTGCGAACGCCAGGACTTGCGCAGCGAGGCCGAGCTGCATTCGCATCGCAAACTCGCCCACAACCTGAAGACGGGCGTCAGTCTGCGCTGCGCCTACTGCTCGGGCAACTATAAGAGTCGCGCCGAGCTGGAGCAGCACATGAAGAGCTGCCACAACTCGAGCGGCAAGCACAAGTGTCTCATCTGCGACGAGATCTTTCCCTCGCCGGCCATACTCGCCGAGCACAAGCTGCAGCACTCCAAGGTGGGGCAGTCCGGCAAGTGCGCCCACTGcggccagcagctggagcatgTGGCCGCCTTCCGCGCTCACCTGGGCGAGCATGGCAACGATGGCAATCTGCCCATGGCCTGCATCTGCTGTCGCCAGACACTGCACTCCGAATTCGAGCTGAGCTTGCATGCCAAATTCCATACCAAATCGCCCAGCTGCAACAGCCTGCAGGAGCCCGTCTGCGCCCTGTGCCTGGAGCCGCTGCCCGGCGCTGGAGAAACGGCCAAGTTGTGCGAGAAATGTTGTCGCAAGCACAATCTGAATGGCAAGCGCAAGGAGCAAGTGCAGCCAACAGCATTAGCTGCcccagctgccgctgcagctgccgccagTGGCTATCTGGAGCATCGCTGTAATCTCTGCAAAATGATCTTGCCACACGCCCAGAAGCTGCAGGAACATCTCGTCGAGCACACGTTTGCCGGCACCGAGCAGCGTGGCTACAATTGCTACATCTGCTCGGCCGTCTTCACGGCACCCGCTGGCCTGCTCGCCCACATAGCGGAGCACGGCACGCGTCCGTACGACTGCAATTTGTGCCCGGAGAAATTCTACTTTCGCGCCGAGCTGGAGCATCATCAGCGAGCGCACGAGCTGCGCACGCAGTCGGCAGCAATTGCAGCCGCTGCGCGCCCCAAGCAGGAGACGCATAGCTCGACGGCCAGCTCACCTCTGACGCTCAGTCCCAGCCACGTCAAGCAGGAGCTCTACGAGTCGGAGCCACCGAATTCGCCAAACGCCGCTGCGCTGCCCgtgcagcaggaggaggaggaataCATCGAGGTGGAGCAAGTGCCGCAGGAGACGCTGCGAGCTGGCGAACTGCTCAGCACCGAGcgctccagcagcagcgcctaA
Protein Sequence: MDAFCLTDMYSTHTSSSYSPSISDGTLTPNSQQQQQQQQQSSQQPQPQAGEEPGEEAKANGDAAQQTELEQELSKPKRPAHLHHHHHHHYHHQQALKLANKLRKINKDAKLAAGQGQGHGTAAKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALASDSSPSRLEFPKRARGQLTSTPTATTIATPTPLLRCSYCPKATEFSSLEQLNAHLQSTHEQQQQQQQQQQQQKDADGQTNGFQLSCEYCTMKFVNIAALFQHMRVTHLDRLSSPNAYYEQFNRLGSPQSKVKSDLAASEKPEQELPTDLSSNKRRPLTSPTQQPPPPPGIFFCNQCNAGLPDFESFRNHLKSHIAEGMQLICPHCGLSLPEQCEYERHVVAHFLISSSEFNCCSASCGKSYAKAEELHQHLLAEHVQTMLKCVLCSELCENRMSMQLHLACAHSQESKLLRCSACLELFRNDADFHVHVKTRHQLGNQGLGNPPAPANPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGIKDKESPVAGNMGSLYVNALLPPLAAAAAAAAAANNANNNNNNNNNSNLHIDYNVAFKGLFGGNNPPSKFYNSPLQVDTKQAPHPALMYGLSQRYLMEMYAAKANSPANASAAELPTPQAVQAATAASASSSSNNSYSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNYKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGQQLEHVAAFRAHLGEHGNDGNLPMACICCRQTLHSEFELSLHAKFHTKSPSCNSLQEPVCALCLEPLPGAGETAKLCEKCCRKHNLNGKRKEQVQPTALAAPAAAAAAASGYLEHRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGYNCYICSAVFTAPAGLLAHIAEHGTRPYDCNLCPEKFYFRAELEHHQRAHELRTQSAAIAAAARPKQETHSSTASSPLTLSPSHVKQELYESEPPNSPNAAALPVQQEEEEYIEVEQVPQETLRAGELLSTERSSSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00538445;
90% Identity: iTF_00502755;
80% Identity: -