Basic Information

Insect: Drosophila hydei
Gene Symbol: hang
Assembly: GCA_003285905.2
Location: NW:646637-663593[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.29 16 5.7 1.0 3 23 270 291 269 291 0.93

2 18 0.82 47 4.3 3.2 3 22 398 417 396 417 0.89

3 18 0.00061 0.035 14.1 3.3 1 22 509 530 509 532 0.90

4 18 0.5 29 5.0 0.1 2 21 544 563 543 564 0.93

5 18 0.00071 0.041 13.9 0.2 2 23 691 713 690 713 0.95

6 18 0.002 0.12 12.5 0.1 1 23 721 744 721 744 0.96

7 18 0.00016 0.0089 16.0 0.2 2 23 830 851 829 851 0.97

8 18 0.00029 0.017 15.1 2.9 2 23 948 970 947 970 0.97

9 18 0.023 1.3 9.2 0.2 2 23 979 1001 978 1001 0.95

10 18 0.0012 0.07 13.2 0.1 1 23 1014 1037 1014 1037 0.97

11 18 0.00013 0.0073 16.3 1.1 1 23 1078 1100 1078 1100 0.99

12 18 0.002 0.11 12.5 0.9 1 23 1108 1131 1108 1131 0.96

13 18 0.069 4 7.7 0.4 2 19 1139 1156 1139 1157 0.94

14 18 2.7e-05 0.0015 18.4 0.4 3 23 1262 1282 1261 1282 0.98

15 18 0.0011 0.061 13.4 0.1 1 23 1317 1339 1317 1339 0.97

16 18 0.00061 0.035 14.1 0.6 2 23 1423 1445 1422 1445 0.93

17 18 0.0066 0.37 10.9 0.3 3 23 1501 1521 1501 1521 0.98

18 18 3.9e-05 0.0022 17.9 2.3 1 23 2003 2025 2003 2025 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.29	16	5.7	1.0	3	23	270	291	269	291	0.93
2	18	0.82	47	4.3	3.2	3	22	398	417	396	417	0.89
3	18	0.00061	0.035	14.1	3.3	1	22	509	530	509	532	0.90
4	18	0.5	29	5.0	0.1	2	21	544	563	543	564	0.93
5	18	0.00071	0.041	13.9	0.2	2	23	691	713	690	713	0.95
6	18	0.002	0.12	12.5	0.1	1	23	721	744	721	744	0.96
7	18	0.00016	0.0089	16.0	0.2	2	23	830	851	829	851	0.97
8	18	0.00029	0.017	15.1	2.9	2	23	948	970	947	970	0.97
9	18	0.023	1.3	9.2	0.2	2	23	979	1001	978	1001	0.95
10	18	0.0012	0.07	13.2	0.1	1	23	1014	1037	1014	1037	0.97
11	18	0.00013	0.0073	16.3	1.1	1	23	1078	1100	1078	1100	0.99
12	18	0.002	0.11	12.5	0.9	1	23	1108	1131	1108	1131	0.96
13	18	0.069	4	7.7	0.4	2	19	1139	1156	1139	1157	0.94
14	18	2.7e-05	0.0015	18.4	0.4	3	23	1262	1282	1261	1282	0.98
15	18	0.0011	0.061	13.4	0.1	1	23	1317	1339	1317	1339	0.97
16	18	0.00061	0.035	14.1	0.6	2	23	1423	1445	1422	1445	0.93
17	18	0.0066	0.37	10.9	0.3	3	23	1501	1521	1501	1521	0.98
18	18	3.9e-05	0.0022	17.9	2.3	1	23	2003	2025	2003	2025	0.99

Sequence Information

Coding Sequence: ATGTGCGACGCTGTCGCCACTACTACAACGACAACATCAATCCCAGCAGCAGGATCAGGATCAGGAGGTGCTGCTGGCGATACCACATTGACAGCAATGGAGGAGCGTACGCGACAAAGTTGCTGTCGCCTGTGCATTGCGCCCGCCAGCGAATGCATTTCGATCATTAACAGTTATGCGGCCGATAAGGAACCGCTGGCCACTAAAATACACAACTGCGTAAATATCAAGatcaCGCCATTGGATCGTCTATCGCTGCATATTTGCCATGCCTGCATCAGCTATTTGAACTCTTGGCAGAGCTTTAAGAATCGCTGCCTCAGCTCACAGTCCAAGCAACGCCAATGGCTGGACAGCGATAAAAGCAAGCAGCAGACGCTTTTGGGATATTTGGATTTGAACAAAACGGAGAATGGCAGCTCCATTGAACAGCACCAGCACGAATCGAATATTGATTCAGCAGCGATTGCAGCTGAAAAGGCGTCCGCCAACATTTTGGATGGCATACCTTCGTTGAAGAAACGCAAATCGTTAACAGTTTATCCGCTGCCCGTCGTACCGATCAAGGATGAGCCCATTGACGATACGGACGATGACTTCCAAATGAAGTGTATAGACGAGTCCGATGATATGATGGATCCCACAATGTTCCTAGAGCGCTCCGAGCATGAGGGCGATGTTCCACTAATGACCTCCGACTATGATTACACGGCGCAACACGGCGTGACGGCGGTTGCGGCGGCGGCATCGCTGCCCGCAAGCGCGGTTGCAAACGTGGCCGCCGCTGGCGACTCAAAGGTGGCCAGCTGTCGGGCCTGCAGCTTGCAGTTCTCGACGCGCGCCAATGCCCGACGCCACGAACGCAATCTGCATCCGAATCTGTTTCAATTGTCGACAGATTCACCAAATAATACGCCCATCACAAAACCAACGCCGGCTTTAGCCGCCGCTCTGGAAATTCAACGTgccgcagcggcggcagcagccacCGCGGAAGCAACCAAAGCCGCCGCCGGTGGCAACATATCAGCGCAAAAGTATCGCCAGGTGGTAATGAATACGTTCATCAAATGCGAAAATGGCGGCTTCGACTACGACAATCCGGAACAGTATCAGCAGCTGCTCACACGCGACAAGGTGGAGTTCATACAAGAGAACAATGAGTTTCTGGAGCAATACCAGACGATGACGTGTCGCTGCTGCAATAAGTACTTCAACACCTACAAGAACTTTATGGCGCATGTGCGCAAAAAGTATCCGCTGCTGCCGCGCAATCTGTGCTTCAACTGCCTGAAGATGAACGACTCGAAGGCGCTGTTCATATCGCATCTGAAGAAGCGCAACTGCATCAATTTGTATCGCGTTCTCAACGCTTTGCGCTTGAAGCAGCCAAACTTTTCGCATGCCAGCGCATCTGGAGCGGCTGTCTCCGCCGATTTGAGCATTGGCCAGGCAGCGGCACACGAAACATCAACGGAGCGGCCCGAGAAGCTGCGTGCCAAGGAGCTGTTGGTGAACAAACTGTATGAGTGCAAGCTGTGCCCGAAGGGTTTTCGCACCAAGCACGAGTTCCGCACGCATGTGTACGACAAGCATGCGGATGTGCAACGCAAGGATAACAATTCGATACAGTGCAGCTTCTGTGAACTGGACTTTGCCGATCCCGTCGATCGTCGTCGCCACTACAACAATATGGACTGCATTGTGCGGTTGCGCTGCATGACCTGCGATGCCAAGCTGGAGACGCATCAGCGCTTCCTCGATCACGTCTACCAGGATCACTTGGGCGGTGTGAGCAGCGATAATGCATCTACAGCTAACAGCGGCATGGATCATTCGCCCGGTAAACGCAGCCTGCTAGGCGCCTTGGGGATTGGTGTGAGTCAGTCATCGAATGATGAGTCACGCAGCAGCAttcataacaataacaatgcagTGGAATCGGCCTTCACCTCAACACCGAAACCAGCTGGAACAGCGGGCggcgcagctgcaacagcgatCAGTGGCGGCTCCACGTCGGGCAGCCGCGATGCACCCAAATCGCAGTATTTCTCCCGCATGCCACAGGTGTGCCCCATTTGTGGCCAACagtacaacaactacaacaacgtGCTGCGTCACATGGAGTCGAAGCATCCCAACAAACTGCCCGAGACATACAAATGTGTGCGCTGCGGCCTGGGCTATCCGCGAATCTCCTATCTGCGCGAGCACATGATCAATGTGCACGGCGTGGACAAGAATCGGCATTCGGGCGGCTTTGAATACATTGTGAATGCCGATGCAGTTAAATTGGCGGATGGCAGCACGCCGAACGTCTATACCGGGCGATATGATTATGTGATGAAGGATCTGATGTCAATAACAAATGGTGGGACACTCgATGATGAGGAGGAGGAAAGCGGAAGCGTTGCCAAAAAGATGCGACtcgacgacagcagcaacaatagcagcatcAACATGAGCATTGCCAATCAGCAGAAGGAGTGTCTCATCTGCAATGCGGTGTTTAGCAACAACATTGGCTTGTCGAATCATATGCGCTCGCATTATACAGCCTCGACGGCGACCAATGCGGCGCTGGCGGCTGCCAATCGCATGACGCCCAAATCTTTGACAATTACTGCAGCTCCGTCATTGGACACGACtgcggcgtcgtcgtcgtccaccagcatggcagcagcaaatgcggcgccggcggcagcagcagcaaccccaACAACAGTCGTCACAGCTGGTGGCAGCTTGCCACCAGCGATGGTGCATCAGACGCCACAGGAACAGGCCGTGTTCCGGCGCAGCTTGGATCAGGCAGCCGATCGCCGCTTTCGACGCATGCGCTGTCGCATCTGCCAGCGCAGATTCAGTTCGAAGAAATCATATCGCTATCATATGCTCACCGACCATCAGGTGCAGAACGTGCAGTTCATCAAGTGCAAGCTGTGCAATGCCGAGTTTGCCTATGAGAAGGGCCTCAAGGTGCATCTGTTCAAGGTGCACGGACGGGCCATAAAGGACGAGATGATTATCAAGCAGTTCGAGTGCGATATCTGTTCGATTGTGTACAGCTCCGAGCTGGAGCTGCAACAGCACAAGCGCAGCGTTCACAAATCCCAAATGGGCGCCAACGATGCGTCCAAGTCATCAACCAAATCATCTACCGCTACCTCAGCTGCTGACCTGATCGACGCATCGGGCACGGCTGTGGCCGCCCTGCCACTCTACTGGTACCAGTGCAAGTACTGCCCATCCAACTTCAATACCAACAAGAAACTGGCCATACACATCAATTCGCACGACGAGTTCGATTCGAACGATTATTCGTGCAAGGATTGCGGCAATGTCTACAGCGGACGCAAGAGCCTCTGGGTGCATCGGTATAAGAAGCATCCGCAGGTACCAGATCCGGCTGAGTGCACGCTGTGCCGCAAGATGTTCTTTGATCGCCAGATGCTGGAGAATCATACGCCCACCTGCAATCGGAAGCCCATCACTGCCACCGGCGCCCATCAGCaggatcagcagcaacagcaccagcaccagcagcagcaacaacaccagcagcaacagctgcaaatgcaacaacatcGCGCCATATTCAAGCATAAAACGGGCGATGAtgacgaggaggaggaggacgatcagcttttgctgctggACGATGGTGCCGTTGGCAGCGATAGCAACGGCGGCAATGTGATCCATGCAGCggccacaagcagcagcaatccaAATACGATAAATGCGAGCACAATGAAGATACGCATACCGGAGGTGGCGTGCACCATTTGTGGTGCTCGATTCACTGACCAGGAGATGTTCACCAAGCACATACAGAAGCACGAACAGGATCTGTATGTGGACAATCCACTGGCGGCCATGTTCGACGATGGCCCAGCCGATGCTGGCCAATTTCAGGTGGAGCGGCAGAACGAGAATGGGGAATATGCGTGCGATTTGTGCACCAAGACGTTCCCCCAGGTGATTGCGCTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGaatccCATCATCGACGGCGAAGCGACAACgctgaacaacagcagcagcaacaacaacaacaacaattcgctGAGCTCCTCGTTGATGCTGCGCGAGCTACATGCAGTGGGTCTGATGcccaaccagcagcagcaccagaaacaactgcaacaacagcagcaacaacaacagcaacggaaCAACACATCGAGCAGCTCGAGCAAGTCGATGAAGCGAAAACGTGAACTTAAATGCGAATATTGCGCCTCCACATtcattagcaacaacaacctgcGACGCCACATGTACGAGCTGCACAAGCACGAGGTCAGCAATCTCCCAGAGCCGCCAGTTATAGAAGTGGATGAGCCGCTAACGTGTCGTCGCTGCGGCGATATACGCTTCGATACCAAAGAGCTGTGGATCGAGCATAAGCTGGCGGACGCCAAAGTGGTTCGTCCGTTCTGTCCATTCCAATGGGGCTGTGATCTGTGCGGCGAGTACTTGTCGCGCAAAGAGAAGCTCATCAATCACATTAACAATCATCTCAAAGAGGATGTGATAGTGCCCGTGGCAACATTGGCGGCTGCCACCAAGGCGGCGCCACCAGTTTCCGTGCTGCCCAACAAgaatgcaacagcaaaaacggCAGctggaacagcaacaacagcagcaggaacagcaacagcaacgggaGTTGGAGCAAAGGGCATAATTAGAGCGGCGGCACCAGCTGGAAAAGTTAATAAGAGTAAACAACTGGAGGAGCTGACAATGAAGGTGGcaacaaaacagcagcaacagcaacagcagcagcagcagtcggcaAATGATGATAATGCTGAGCAAGATGATGAGGCGGACGATAGTGATatggatgatgatgatagcGATAGTGGCGATGGGGATAGCACAagtgctgatgatgatgatgaggacgacgacgatgatgacgatgagggCGAAgttgacgacgacgacgatgatgatgatgatgaagatgtgGATGGAGCTGTTGTcgaacaacaattgctgcaacaaaaacaacaacaacagcagcagcaacaacaacaacaacaaagtcagCCCctcaatagcaacaacagcagccacagcaatagCGTAGTTGCaaacgatgatgacgatgacctCATTGAGGAAGTCATCGAGGAAGATGGCATTGTCGAGGAGTtagacgacgatgatgacgacgatgaggatgacgacggcgacgacgatggTCATACAACCGATGAGCATCAACAGCTGACAGCCAATGCAAAGCAGCAGACGAGACGCCTCAACTTTGACTACTCGCGCTCAGACAGCGCCAAGCTGAACGGCAATGGGAAAGTgacgccgcagcagcagcagcagcagcagctggcaaagtCAAAGGGACAGCCGGCGGCGGTGCTGGTCATGCATAGTTCCGAGGAGGACGAGGATGAGgatggtgttggtgttggtcatgtcgatgatgatgatgaggatgaggagggCGTAGGTGAAGCGATGACCATTGATGATATTATTGAAGAAGATGATGGGGAGGATGATGACGATGTGGTTGGTGTCGGTGGCGGTGTTGttgaggatgatgatgatgacgatgatgatgttgagGAAGATTTGGATgaggatgacgacgatgatgatgatgatgacgacgacgatgatgacgacgacgacgacgacgatgatgatggcgTCAAtattggcaacaacaatcgtCGTCGCGGCGGTGCTGTGATGGTCAGCGGCATCAGCATTGGCGACGGTGAGGCTGATGATggtgttgctgatgctgatggcgATGGTGATGGTGATGGGGATGGTGATGCTGATGGTGATGTGGATGCTGATGCTACATCATCATCTGAGAGCGagtcaacgacaacaacatcgCATTCAATTGGTGAGCGGCGTAAAAAATCAGTAGTTAAATCAGCGGCACATGGCGCTGCCACTGATCAGTCTAATTCCACCTATACGTGTGATCTATGTCAACTTTGTTTCGATTCTCAGGAGCAACTGCAGTCACATATTAAAAGCCATTTTCTGAATGGGCCGTCGGCgggtggcagcagcggcagcagcgccagcaacagcggcaattGCAGAAGAATCGGTGTcagcgctggcagcagcagcagcggcaggacccacaacaataataataataataataataataataataataataataataataataacaataataataacaataataataacaataacagcaaaagcaaaaccaaaaagtCCGGCTTGGATGCAACGAAAGGTgacaatgctgctgctgctgcaacaacagcagcaacgacaacagcagcagcaacaacaacaacaacaacatcaacgacaacagcaacagttgccgctgaagcagctgcagcaacagcagctgcagacaCAGCCAGCAGCTTGAACTGA
Protein Sequence: MCDAVATTTTTTSIPAAGSGSGGAAGDTTLTAMEERTRQSCCRLCIAPASECISIINSYAADKEPLATKIHNCVNIKITPLDRLSLHICHACISYLNSWQSFKNRCLSSQSKQRQWLDSDKSKQQTLLGYLDLNKTENGSSIEQHQHESNIDSAAIAAEKASANILDGIPSLKKRKSLTVYPLPVVPIKDEPIDDTDDDFQMKCIDESDDMMDPTMFLERSEHEGDVPLMTSDYDYTAQHGVTAVAAAASLPASAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAAAATAEATKAAAGGNISAQKYRQVVMNTFIKCENGGFDYDNPEQYQQLLTRDKVEFIQENNEFLEQYQTMTCRCCNKYFNTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNALRLKQPNFSHASASGAAVSADLSIGQAAAHETSTERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCELDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVSSDNASTANSGMDHSPGKRSLLGALGIGVSQSSNDESRSSIHNNNNAVESAFTSTPKPAGTAGGAAATAISGGSTSGSRDAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDEEEESGSVAKKMRLDDSSNNSSINMSIANQQKECLICNAVFSNNIGLSNHMRSHYTASTATNAALAAANRMTPKSLTITAAPSLDTTAASSSSTSMAAANAAPAAAAATPTTVVTAGGSLPPAMVHQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIIKQFECDICSIVYSSELELQQHKRSVHKSQMGANDASKSSTKSSTATSAADLIDASGTAVAALPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECTLCRKMFFDRQMLENHTPTCNRKPITATGAHQQDQQQQHQHQQQQQHQQQQLQMQQHRAIFKHKTGDDDEEEEDDQLLLLDDGAVGSDSNGGNVIHAAATSSSNPNTINASTMKIRIPEVACTICGARFTDQEMFTKHIQKHEQDLYVDNPLAAMFDDGPADAGQFQVERQNENGEYACDLCTKTFPQVIALKVHRKWHFRGDSKQNPIIDGEATTLNNSSSNNNNNNSLSSSLMLRELHAVGLMPNQQQHQKQLQQQQQQQQQRNNTSSSSSKSMKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIEVDEPLTCRRCGDIRFDTKELWIEHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLINHINNHLKEDVIVPVATLAAATKAAPPVSVLPNKNATAKTAAGTATTAAGTATATGVGAKGIIRAAAPAGKVNKSKQLEELTMKVATKQQQQQQQQQQSANDDNAEQDDEADDSDMDDDDSDSGDGDSTSADDDDEDDDDDDDEGEVDDDDDDDDDEDVDGAVVEQQLLQQKQQQQQQQQQQQQSQPLNSNNSSHSNSVVANDDDDDLIEEVIEEDGIVEELDDDDDDDEDDDGDDDGHTTDEHQQLTANAKQQTRRLNFDYSRSDSAKLNGNGKVTPQQQQQQQLAKSKGQPAAVLVMHSSEEDEDEDGVGVGHVDDDDEDEEGVGEAMTIDDIIEEDDGEDDDDVVGVGGGVVEDDDDDDDDVEEDLDEDDDDDDDDDDDDDDDDDDDDDDGVNIGNNNRRRGGAVMVSGISIGDGEADDGVADADGDGDGDGDGDADGDVDADATSSSESESTTTTSHSIGERRKKSVVKSAAHGAATDQSNSTYTCDLCQLCFDSQEQLQSHIKSHFLNGPSAGGSSGSSASNSGNCRRIGVSAGSSSSGRTHNNNNNNNNNNNNNNNNNNNNNNNNNNNNSKSKTKKSGLDATKGDNAAAAATTAATTTAAATTTTTTSTTTATVAAEAAAATAAADTASSLN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00479624;
90% Identity: -
80% Identity: -