Basic Information

Insect: Drosophila hydei
Gene Symbol: ken1
Assembly: GCA_003285905.2
Location: NW:3277502-3282920[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 24 0.04 2.3 8.4 7.0 3 23 244 264 242 264 0.96

2 24 0.00015 0.0086 16.0 1.2 1 23 270 295 270 295 0.94

3 24 0.032 1.8 8.7 0.2 2 23 303 327 302 327 0.92

4 24 0.0011 0.063 13.3 5.1 1 23 337 359 337 359 0.97

5 24 0.00039 0.022 14.7 1.9 2 23 367 388 366 388 0.96

6 24 0.014 0.78 9.9 0.5 1 23 394 416 394 416 0.97

7 24 0.037 2.1 8.5 2.6 1 23 422 445 422 445 0.97

8 24 0.0029 0.17 12.0 1.9 1 23 451 473 451 473 0.97

9 24 0.0082 0.47 10.6 0.6 2 23 480 501 479 501 0.97

10 24 0.00035 0.02 14.9 0.8 1 23 587 610 587 610 0.95

11 24 0.18 10 6.4 1.3 1 21 616 635 616 638 0.75

12 24 0.00012 0.0068 16.4 2.2 1 23 644 667 644 667 0.98

13 24 0.02 1.2 9.3 5.7 1 23 1041 1063 1041 1063 0.97

14 24 0.00042 0.024 14.6 0.9 1 23 1069 1094 1069 1094 0.94

15 24 0.0043 0.25 11.5 0.3 3 23 1103 1126 1101 1126 0.90

16 24 0.0049 0.28 11.3 4.8 1 23 1136 1158 1136 1158 0.97

17 24 0.00039 0.022 14.7 1.9 2 23 1166 1187 1165 1187 0.96

18 24 0.014 0.78 9.9 0.5 1 23 1193 1215 1193 1215 0.97

19 24 0.0029 0.16 12.0 2.0 1 23 1221 1244 1221 1244 0.98

20 24 0.0025 0.14 12.2 1.9 1 23 1250 1272 1250 1272 0.97

21 24 0.0036 0.21 11.7 0.8 2 23 1279 1300 1278 1300 0.98

22 24 0.00069 0.039 14.0 0.8 1 23 1383 1406 1383 1406 0.95

23 24 0.36 21 5.4 1.7 1 19 1412 1430 1412 1434 0.73

24 24 0.00088 0.05 13.6 3.1 1 23 1440 1463 1440 1463 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	24	0.04	2.3	8.4	7.0	3	23	244	264	242	264	0.96
2	24	0.00015	0.0086	16.0	1.2	1	23	270	295	270	295	0.94
3	24	0.032	1.8	8.7	0.2	2	23	303	327	302	327	0.92
4	24	0.0011	0.063	13.3	5.1	1	23	337	359	337	359	0.97
5	24	0.00039	0.022	14.7	1.9	2	23	367	388	366	388	0.96
6	24	0.014	0.78	9.9	0.5	1	23	394	416	394	416	0.97
7	24	0.037	2.1	8.5	2.6	1	23	422	445	422	445	0.97
8	24	0.0029	0.17	12.0	1.9	1	23	451	473	451	473	0.97
9	24	0.0082	0.47	10.6	0.6	2	23	480	501	479	501	0.97
10	24	0.00035	0.02	14.9	0.8	1	23	587	610	587	610	0.95
11	24	0.18	10	6.4	1.3	1	21	616	635	616	638	0.75
12	24	0.00012	0.0068	16.4	2.2	1	23	644	667	644	667	0.98
13	24	0.02	1.2	9.3	5.7	1	23	1041	1063	1041	1063	0.97
14	24	0.00042	0.024	14.6	0.9	1	23	1069	1094	1069	1094	0.94
15	24	0.0043	0.25	11.5	0.3	3	23	1103	1126	1101	1126	0.90
16	24	0.0049	0.28	11.3	4.8	1	23	1136	1158	1136	1158	0.97
17	24	0.00039	0.022	14.7	1.9	2	23	1166	1187	1165	1187	0.96
18	24	0.014	0.78	9.9	0.5	1	23	1193	1215	1193	1215	0.97
19	24	0.0029	0.16	12.0	2.0	1	23	1221	1244	1221	1244	0.98
20	24	0.0025	0.14	12.2	1.9	1	23	1250	1272	1250	1272	0.97
21	24	0.0036	0.21	11.7	0.8	2	23	1279	1300	1278	1300	0.98
22	24	0.00069	0.039	14.0	0.8	1	23	1383	1406	1383	1406	0.95
23	24	0.36	21	5.4	1.7	1	19	1412	1430	1412	1434	0.73
24	24	0.00088	0.05	13.6	3.1	1	23	1440	1463	1440	1463	0.97

Sequence Information

Coding Sequence: atgaatgaAGGGAGTGAATACTCCATACACTCGATATGTCGCATATGCTTGAACCATTTGCGGAACGATCCAGCATTCGACCTGTTTCTTGTCCCTGGTCTGGCTAAGAAACTTTGTGTGTGCACTTCACTCTCAGTGGAACAGCACGATGGCTTCCCGAAAAACCTTTGCTCTACTTGCCATACCCGGCTTAACGACTTGCATGACTTTCAGAAGCAATGCGTGGATTCTGTGCAAAAGTTTCAAGAAATGGTCGCGAGCAATTACTTTGTCCCAGTCATGGGCGATGTTGACAAAGTTGATGTAATGCATGATGCACCTACTGATGGAGACATGGAAGAGGATCGTTTAAATTTCGATCCACttctaaatactaaaatagAGATAGTGGAGACTGAAGATGTTTTTAAAATGCTAGATGATGTGGACCGAGAAGTTGAGGAGGCTGAGAATGAGCTCTCCAGTGACAACGAAAGTGACAAAGATGTTGATCCGGAATTCGAAGTAAATAGTAGCAACTCTGAAGATGCTGTGCCTCTGTCCCGCTTACGAAGTTCGACCAGAGCATCGAAAGCAAATGCTAAGACCAAACCTGTagcagatgatgatgattctTCTAGCTTTGAGTGGAATACTAATAAAGATGAGATTAAGGAAACACCTAAAACGAAAGCGAAACGTAAGCGTATGCCGAGGCGCGACGCATCACTGGATCCTGATCAGATTGATTGTCACATTTGCCATAAGAAATTCAAGAGCACTAACCTCTATGACGAGCATATGAAGCATCATAATGATCTTTTGCCATTCCAATGCACTGTAGAGACCTGTAAGAAAGGCTTCACTACTTCAAGTGGGTTACGCCTTCACATGGATCATGCTCATTCGGAACTCTCGGAGGTTCACGCGTGTTCTGTTGAGGGATGTGGCATGACATTTCCTCGTCCTGTTCTACtaacatttcatttgaaaaaggTACACAAAGTAATCACCTCTCGGGCCAAGGATCATCCTTGTACGGAATGTGATAAGGTATTCCGTTGCTCCACAGCTCTTAAGAAACATATGTACAAACATACTGGAGAGGAGAAGCCAATATCCTGTAACATCTGCAACAAACGTTTCCACATAAACAGCGAACTCAAGGATCATCTCTTGCGTCATGCCGGTGTGAAGAATCACGTTTGTCCGTACTGTGGTGTTGGTAAAACAACTCGACAGGAATggaataaacatatattaacaCACACCAAGGAAAAACAATTCCAATGTCGTCAGTGCGATCATTCCTCCCACAACAAACAAGCCCTGGCCAATCATGTtaaagtggttcatttgaagatTAAGAACTATGCCTGCCAATATTGTGGCAAGACCTTTGGCAAATCGTATGCCTGCAAAATTCACGAGAGAATCCACACTGGGGAAAACTGTTCGCAGTGTAAAATCTGTGGTAAGGTCTTGCTTTTTGAAAGGAGTTTGACTAAACATCTAAAGATTCATGAGAAGCGAGATATACACGCTTCAGCGAGTAGTGGGAAACCACAGACAGTTAATGATGCGCAGAATATGAATCGAGATCCAAATGATCCTGTGGAGGTGAAGCCCGTACCAATAGAGCAAGCCAAGCCGAAAAATACAAATAGGTTAGAGCGTGTAGATATTTCCGAGTTGGCCGGTACCTCCGTAAATCCCATTCCCACAGTCTCTGTGGCATCCTGGTCCCCCCAAGTAAACTTCACTAAGAAGGAGGGCCAGCACATTTGTCCgggatgtgggcgtggcttcaACCATATTGGCAACATGAAGCTTCACTATAAGATAATACATGAGAAGGTAAAAGATTTCGCCTGTCGCTTCTGTCCCAAGCGATTCTCTAAGGCTCAAATATTACGGCATCATGAATGGATCCACACTGGTGAAAAGCCGTATGAGTGCAAGATATGTGGCAAACACTTCCGTCAGGAGCAAGTAATGAAAACGCATGTAAGAAAAGTACACGAGAATCCGGCGAAGCCTCCAAGAgaaccaaagcctcaaaaacCTGCTAAAGAAAAAAGATCGAAGATGAACCTCAACACAAAACCACCTAAGATTCTTGATGAATACCAAGATCCTGCTGCAGAACGCgctgcagctactgctgctctgCTCGCTCAACAAATAGAAGAGAGCCAGGCAAAGCGAAAGGCCGAAGAAGAAATTCGTAAGATTCAAGAAGCCGCTTGTGAACAACTTCAGATGCTGCAGAAGGAACAGCTTATTGACAAGCTACCCAGTGATAGCTTTCAAGTAAAAAAGCCTGAAACAGGTATCAGTGTAGATGACCTCAAACAAgattaTTTCATACAGTTATACACTTATCTGAAGAAAAAGGAGATAAGCAAAATGAATGAGGGGAGTGAATACTCCATACATTCGTTATGTCGCATTTGCTTAAACAATTTGCGAAACGATCCGGCATACGACCTGTTTTTAATTCCTGGCTTGGCCAAGAAactttgtgtgtgtacttCACTTTCAGTCGAAGAGCACGATGGCTTCCCAAAAAACATCTGCAGTTCTTGCTACACCCAACTCAACGACTTGCACGGATTTCAGAAGCTTTGCGTGGACTCTGTGCAAAAGTTTCAGGAAATGCTCGCGAGCAATTATTTTGTACCCGTCATTGCTGATGTTGACAAAGTTGATGTGATGAATAATACTGTCCCAGATGGGGACATGGACGAGGATCGGAGTAACTTTGATCCCCTTCTCAACACTAAAATAGAAATCGTGGAGACTGAAGATGTTTTTAAAATGCTAGATGATGTGGATAAAGAAGTTGAGGAGGTTGAGAAGCAGCTCTCTAGTGATGTAGAATTCGAGCATGATGACGATCCGGAATTTGAAGTAAATAGCAGCGACTCAAATGACGCCATGCCCCTGTCTCGTTTGAAAACTGTTACTAGAGCGTCAAAGACCAAAAGCAAACCTGTAGTAGATGACAAAGACAAGGATAAAGACAAAGAATCGTCGGACTTTGAATGGGAAATGGATAGTGACTATGACAAAGAAATACccaaaaccaaatcaaaacgAAGACGCAAACCAAAACCCAAAGTTCAACCGGATGATGCGTTTGATTGCCACATTTGCAATGAAAAATTCAAGAGCACCAAACTTTATGATGAACATATGAAGCATCACAACGATCTTTTGCCGTTCCAATGCACTGTGGAGACTTGTAAGAAGGGCTTCACCACATCTGGTGGTCTACGCCTTCACATGGACCACGCTCATTCGGAACTCTCGGAAGTTCACGCCTGTTATGTTGAGGGATGTAGTATGACATTTCCTCGACCCGTTTTACTCACGAACCATTTGAAAAAAGTTCACAAAATTATTACCTCTCGAGCCAAGGATCATCCTTGTACGGTGTGTGAGAAAGTTTTCCGTTGTTCAACAGCCCTTAAGAAACATATGTACAAACATACTGGAGAGGAGAAGCCGATTTCCTGCAATATCTGCAACAAACGCTTCCACATAAACAGCGAACTCAAGGATCATCTCTTGCGTCATGCCGGTGTGAAGAATCACGTTTGTCCTTACTGTGGTGTTGGTAAAACAACTCGACAGGAATGgaacaaacatatattgaCGCACACCAAGGAAAAACAGTTTCAGTGCGATCAATGCGATCATTCATCTCACAACAAGCAGGCTCTGGCAAATCATATTAAAGTGGTGCATATGAAGATTAAGAACTATGCCTGTCAGTATTGTGGCAAGACCTTTGGCAAGTCGTATGCCTGCAAAGTTCACGAAAGAATCCACACTCGCGAAAATTGCTCTCAGTGCAATATTTGTGGCAAAGTATTGCTTTTTGAGAGGAGCTTgacaaaacatttgaaaactcATGAGAAACGTGAGCTTCGCGCAACAGCTACAAAAGGGCGCCTTAAAGATGATGCCCAGAGTAGCCAAGAGACAACTGAACCTGCAGAGATGAAGCTCATACCAACGGAGCCACCTAAGCCGAAAAACGGAAATAGGTTAGAGCGTGTAGATATTTCCGAGTTGGCCGGTACCTCTGTCAATCCCATTCCTACAGTCTCTGTGGCATCCTGGTCCCCTCAAGTAAACTTCACTAAGAAGGAGGGCCAGCACATATGTCCgggatgtgggcgtggctttaACCACATTGGCAACATGAAAATTCACTTTAAAATTGTACACTTAAAGGTGAAAGATTTCGCCTGTCGCTTCTGTCCCAAACGATTTTCAAAGGCACAAATCTTACAGCATCATGAATGGACGCACACCGGCGCAAAGCCTTTCCAATGCAAGTATTGTGGTAGACATTTCCGGCAGGAGAAAGTGATGAAAGTACATGCCAAAAGGGTACACGAGAATCCGAAGAAACCTGAAAAAGAGGCTAAACCTCCAAAAGAGCCCAAGCCTCCAAAAGATCCTAATAGGGAAAAAAGGCAGAAGATGAATCTCAACGAGAAACCGCCCAAGATTCTTGATGAATATCAAGATCCTGCTGCAGAACGCgctgcagctactgctgctctgCTCGCTCAACAGAAGGAGGAGTATAAAGCCAAGCAAAGGGCGGACGAGGAAGCGCGTAAGATTCAAGAGGCTGCATGCGAACAACTTCAGATGCTGCAGAAGGAACAGCTTATTAACAAGCTACCCAGTGATAGCTTTCAAGTAAAGAAGCCGGAAACAGGCATCAGTGTGGATGATCTGAAAGGAGACTAA
Protein Sequence: MNEGSEYSIHSICRICLNHLRNDPAFDLFLVPGLAKKLCVCTSLSVEQHDGFPKNLCSTCHTRLNDLHDFQKQCVDSVQKFQEMVASNYFVPVMGDVDKVDVMHDAPTDGDMEEDRLNFDPLLNTKIEIVETEDVFKMLDDVDREVEEAENELSSDNESDKDVDPEFEVNSSNSEDAVPLSRLRSSTRASKANAKTKPVADDDDSSSFEWNTNKDEIKETPKTKAKRKRMPRRDASLDPDQIDCHICHKKFKSTNLYDEHMKHHNDLLPFQCTVETCKKGFTTSSGLRLHMDHAHSELSEVHACSVEGCGMTFPRPVLLTFHLKKVHKVITSRAKDHPCTECDKVFRCSTALKKHMYKHTGEEKPISCNICNKRFHINSELKDHLLRHAGVKNHVCPYCGVGKTTRQEWNKHILTHTKEKQFQCRQCDHSSHNKQALANHVKVVHLKIKNYACQYCGKTFGKSYACKIHERIHTGENCSQCKICGKVLLFERSLTKHLKIHEKRDIHASASSGKPQTVNDAQNMNRDPNDPVEVKPVPIEQAKPKNTNRLERVDISELAGTSVNPIPTVSVASWSPQVNFTKKEGQHICPGCGRGFNHIGNMKLHYKIIHEKVKDFACRFCPKRFSKAQILRHHEWIHTGEKPYECKICGKHFRQEQVMKTHVRKVHENPAKPPREPKPQKPAKEKRSKMNLNTKPPKILDEYQDPAAERAAATAALLAQQIEESQAKRKAEEEIRKIQEAACEQLQMLQKEQLIDKLPSDSFQVKKPETGISVDDLKQDYFIQLYTYLKKKEISKMNEGSEYSIHSLCRICLNNLRNDPAYDLFLIPGLAKKLCVCTSLSVEEHDGFPKNICSSCYTQLNDLHGFQKLCVDSVQKFQEMLASNYFVPVIADVDKVDVMNNTVPDGDMDEDRSNFDPLLNTKIEIVETEDVFKMLDDVDKEVEEVEKQLSSDVEFEHDDDPEFEVNSSDSNDAMPLSRLKTVTRASKTKSKPVVDDKDKDKDKESSDFEWEMDSDYDKEIPKTKSKRRRKPKPKVQPDDAFDCHICNEKFKSTKLYDEHMKHHNDLLPFQCTVETCKKGFTTSGGLRLHMDHAHSELSEVHACYVEGCSMTFPRPVLLTNHLKKVHKIITSRAKDHPCTVCEKVFRCSTALKKHMYKHTGEEKPISCNICNKRFHINSELKDHLLRHAGVKNHVCPYCGVGKTTRQEWNKHILTHTKEKQFQCDQCDHSSHNKQALANHIKVVHMKIKNYACQYCGKTFGKSYACKVHERIHTRENCSQCNICGKVLLFERSLTKHLKTHEKRELRATATKGRLKDDAQSSQETTEPAEMKLIPTEPPKPKNGNRLERVDISELAGTSVNPIPTVSVASWSPQVNFTKKEGQHICPGCGRGFNHIGNMKIHFKIVHLKVKDFACRFCPKRFSKAQILQHHEWTHTGAKPFQCKYCGRHFRQEKVMKVHAKRVHENPKKPEKEAKPPKEPKPPKDPNREKRQKMNLNEKPPKILDEYQDPAAERAAATAALLAQQKEEYKAKQRADEEARKIQEAACEQLQMLQKEQLINKLPSDSFQVKKPETGISVDDLKGD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -