Dhis012943.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila histrio
Gene Symbol
RREB1
Assembly
GCA_958299025.2
Location
OY282582.1:53130971-53137871[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.039 3 8.7 0.8 1 21 260 280 260 282 0.93
2 13 0.00036 0.028 15.1 0.2 1 23 292 314 292 314 0.98
3 13 8.7e-05 0.0068 17.1 7.3 1 23 320 342 320 342 0.98
4 13 0.33 26 5.8 1.7 2 19 552 569 552 571 0.95
5 13 0.044 3.4 8.6 0.0 1 23 745 767 745 767 0.97
6 13 1.3e-05 0.001 19.6 0.7 1 23 777 799 777 799 0.99
7 13 0.00089 0.07 13.9 2.0 1 23 805 828 805 828 0.97
8 13 0.0032 0.25 12.1 2.0 1 23 1104 1127 1104 1127 0.95
9 13 9.3e-05 0.0073 17.0 0.3 2 23 1483 1504 1482 1504 0.97
10 13 0.16 12 6.8 6.3 1 23 1510 1533 1510 1533 0.97
11 13 4.8 3.8e+02 2.1 3.6 1 23 1672 1695 1672 1695 0.79
12 13 0.0091 0.71 10.7 0.5 3 23 1759 1779 1757 1779 0.96
13 13 0.0014 0.11 13.2 4.8 1 23 1785 1807 1785 1807 0.99

Sequence Information

Coding Sequence
atgatgctggcaacacagcaacaacaacaacaacacacatccacaacaacagcagcaactgctgctgctgctgctgctgcaacaacaacagttgctcaCAGCAGCGACGCCAGCGACATGGATCGCCAGCGTCGTGATTCTACCACCTCGGAGTCCTCGCTGGAGCATCTCGACTTGGGGCGCACGCCAAAGaagctcagcagcagcaacggcgcGCCGCAGCCAACGTCGACGCCGCATgacacgacgacgacgacgacgacggcgacgtcgcGTAAGCGTAAACtgcgccagcagcagcaacaacaacagcagcaacatttgcacTCCGATGAGGatgaagagcaacaacaacaacagcagcagcaacaacaacaattagatCAGTCAGCGCAGCGACCGCGTCACAAACAGCGACGCAGCGTCaacgcagctgctgctgctgccagcgCCAGCATTGTCGTCGATTACAGCGCCAGCGGAGACGCCAGCTCACTGCGTAAAAAGTTTCGACTGAATCGCAGCGTCGGCAGCGGCGAACTTAGCGAGTCGGGTTTCGTTGATGGCAGCGCTAACAGCGCTTATTTGCTCAGCAGCAGCGCCGGCAGCAGCGCTCAGTCGGCGTCGGCAACAGCTAACggcgcagtcgctgccgctgccgctgccgcagtCGCAGCACAGCAGGCGTCGTCAAGCAGCTCGGGCGGATCATCGCCGCAAGGTTTATGCCTCTCGAGCGCCGAGTCGGGCATCGGCGCCGGCGACGATCACATGAAATATCTGTGTCCCATCTGTGAGGTCGTCTCGGCCACGCCCCACGAGTTCACCAATCACATACGTTGCCACAATTACGCCAACGGCGACACCGAGAATTTCACCTGCCGCATCTGTTCGAAGGTGTTGTCTTCTGCCTCATCGCTGGACAGACATGTGTTGGTTCACACGGGCGAACGACCCTTCAATTGCCGTTATTGCCATTTGACATTCACAACGAACGGCAACATGCATCGTCACATGCGAACACACAAGCAACATCAGGctacacagcagcagcagcagcagcagcagcaacaatcgcagtcacagcagcagcaattgtcacagtcacagcaacagtcgcagtcgcagtcacagcaacaacagcacacacagcgacgacagcaacatgcggcaacaacagttgccacaCAGGTGACAGGCAGATCGGAGAGTTATGAAAGTGATGCTAGTTGCTCGACGGATGTGTCCAGTGCACAaagtcacagcagcagcagcaatcactccaacaacaacaacaacaatcacaagctgagcaacaataacaacaacaacaataatgatgaGGAGGAAGTGGAAAATGCTGCAACAATGTGCGGCAAACAGCGGCGTCacaaaatcaatattaataacaataatattgaggaggagcaggaggaggaggaggaacatGAAGAGGAGGagcatgatgatgatgaagatgacaATGTGGCACAATTGATAACCTCCACGCCCGATGTGGCAACTCTGCTCGCCTCCGGCGACAGCACACCAAATCAAATGCTGCTCAGTTGTCCCGCCTGCACGGCGGATGAGTTTGAAACGTTGCCGGCATTGTGTCAACATCTGGATGCCGAGCATTCTGATATACCCGCCAAGTGCAGGGAATGCGATGTCATCTTTGCCAGCCATCGACAATTGCAGATGCACAGTTGTGCCGGCAGCAATGGATTGCAAATGTTGCCGCTAATTGGTGCAAGTTCGAGTCCCAAACACAAGCAGGAAATTGAAGATGTCctcgaggaggaggaggaggacgacGAAGATGAGGCGAATGCTGAGGCAGACGATTTAGATatggagcaggagcaggagcaggatcATGAAATGGATcaagagcaacaactacaacatcaacaacaacaacatcaacaacatcccGCACACAAATCCGACTTCTTTCAACAACTCTATCTGAAGGGTAAATCAAATGTGATTGCCCCATTGCCATCGCCCATTAAACATGAGCTAACCGATAGTCGTCAGGACTTGGCGGACATACAGAGCATTCTCAACATGACCAGCTCCAGTTGCACCTCAAGTTTTCTGCGCAATTTCGAGCAATCCGTCAATACGCCCTGTTCCAGTCAATACAGTTTGGATGGACGCGATGGCGAGGAGGAGGCACAAGATGCATTCACCAGTGAATTTCGACGCATGAAATTACGCGGTGAATTCCCCTGTAAACTGTGTGCCGCGGTCTTTCCAAATTTGCGTGCCCTCAAGGGTCATAATCGTGTCCATTTGGCAGCCGTGGGACCAACTGGCCCATTTCGCTGCAACATGTGTCCCTATGCGGTGTGTGATAAGGCGGCACTTGTCCGTCATATGCGTACACATAACGGCGATCGTCCCTATGAATGTGCCGTCTGCAATTATGCATTTACCACAAAGGCAAATTGTGAACGACATTTGCGTAATCGTCATGGCAAAACGAGTCGCGAGGAAGTCAAACGTGCCATTGTCTATCATCCAGCCGAAGATGCAAGTTGTGAGGATTCCAAGTCGGGTCAGAGATTGCAGGAATCTGAATTGGAATTGAGCTATCGTTCGGTGTCGCCAGTGGAGCCAGCTTCCCAATTGAAGCATATGTTGCAAGCGGAATTgccaacaacagttgcagctgctgctgctgcggtcaCGGCTGTTAAAGCAACACCGCTGAAAATACAAGTGAAAAGTTTGGATCAATTGGTGGATAAACCATTGGCGCCTGCCTTGGATCTTAGCATGGATGTTTTAGATCTAAGCAAGAAGCCAACGGCGGCGCAGGAATTGCAGGAACAGCGGGAGCGTGAAAGAGAAAGGCAGCATGAATTGCTGTtgtgtcagcagcagcaacagcagcagcagcaacagcagcagcagcagcaggtgcaacagcagcagcagcaacttttTGGCGCTGGCGATGCTGCCACACAGTATATGCAACAGCTGTTCCGCAATCTCATGTTCCAGCAATCTCCTGCATTTCCCTTCTTCGGCTTTATGCCGCCAACAACAGCTGGCGAGCAAGCGTCAACGTTaccagcaacagttgccgctgccgctgccgccgccgccgccgccgctggcACTGGCACGCCAGCAACATCAGCCCTTACGCCAGCAACGGGCGGACTTTCTTTACCGCTGCcaggcgttggcgttggcgtacCCGTTCCCGCCGGCGGTCCCGTCAAAatggtcattaaaaatggcgttctaatgccaaaacaaaaacaacgtcGCTATCGCACCGAACGTCCCTTTGCCTGTGAACATTGCTCGGCGCGTTTTACGCTGCGCTCGAACATGGAGCGACATGTGAAGCAGCAACATCCGCAATTCTATGCGCAACGTCAGCGCAGCGGACATCATGTGATGCGTGGACGTGCGGCAAGCTCAAgtacggcagcagcagcagcagcagcagcagctgcggcagcggcagcagcagcagcagcaatgtcAAATCTcagccagcaacaacatggaCAACATGCACATCATGCGCACATTTCCGAGCAAGTTAAATATGCCATATTGGCACAGCAATTAAAGGCACGCAAGGATACGGATTTGTTGCAACAGGCATTGGCGCACGGTTCAAGCAGTGTGGCAGCTAATTCATTGCTGCATTTTGGctacaagcagcagcaacaactgcaacaacagcacggCAGCAATATGCCAGCAGCTagcaatgatgatgatgagcccAAGTTGATTATCGATGAggatgatgaggaggaggatgatgggctggatgaggatgaggatgagttggagttggatgagttggagttggagcagcagcagtttgaggagcaacaacagttggATGAGCAGCTggaggagcaacaacagcagcaaccagcACGCACTTCCACGCCCATTGAGGCGGCCAAAAAGGTGGCCGAAACAATATTAGAACAAGCCATTAAAGCTGGCAAGACCACAAGCGATGACTGCAATAACTTGCCattaaaagcagcagcagcagcagcaacaacaaccgctgcaactgctgcaactgcaactgcaactgcaaccactgcaactgcaactgcaaccacTATGAAAACTTTGTTAGCTCAAGCGGAAGCTGTTGCCAAATCCTTAAAAGAAGTTGCCAGCTCACCGTTTAAAGATGAATCTCCCGATTTGGTGCCCGTGGCAAAACTAGTTGACAACGCCACGAGCAATCAAGTATCCTTCAACAGTTACTTTCGTCCCAGCGATGTTGCCAATCATATGGAACAATCCGACGAGGAGGGACTTGTGGCCAGCGGCAGTGCCAGTGAGAGCAACAATTCTGGCACCGAGGACgtaaccagcagcagcagcagcagcggcaatgaaccaaaaaagaaatccGCCTACAGTCTGGCCCCAAATCGTGTTAGTTGCCCGTACTGCCAGCGCATGTTTCCCTGGAGCAGCAGCCTGAGGCGACACATTTTAACGCATACCGGACAGAAACCCTTCAAATGCTCCCATTGTCCATTATTGTTCACAACGAAAAGCAATTGTGATCGTCATTTGTTGCGTAAACATGGCAATGTTGAGAGTGCAATGAGTGTTTATGTGCCCACGGAGGATGTTAGCGAACCGATACCGGTGCCGAAATCTGTTGAGGAAATCGAACTGGAGGAACAGCGACGCAGGGAGCGCGAAAGGGAGCGGGAGCGTCAGCAGTTGGAGCGTGAAagggaacagcagcagcagagggaGCTGGAAAAACAGCAGCGTGAACAGCGTGAAAAGGAGCAGCAAAGACAGCGAGAATTGCAAATggagcgacagcagcaacagcaacagcagcagcaacagcagcaacagctaatGCAACAACTAGCAGCAGCTGCACAAATTGTTGCCGCCTGCAATGCAACGTCAGCAACATCCCCAtcaccaccagcagcagcagcagcgtgcAACAATGTCGAATCGCAAGCCAGCGATTTACCCTATAAATGTCATCTCTGTGAATATTCATTTGGCGAGCGTCTGCAATGTTTGGAGCATATTAAACAGCAGCATGCTCAAGAGTATGCATTACTTTTATCCAAGGGCGCCATTGAAATGGAGGAGCAACAGTTGTCGTTATCgtcgttgccattgccgccaccgccgcctccgacgacaacagcaacagcaacagtttccGATGAAGAAACTGCCGCACGTGCCACAACCAAATATCCTGATTATAGCAATCGCAAAGTGATTTGTGCATTTTGTGTTCGTCGCTTTTGGTCCACAGAGGATCTGCGTCGTCATATGCGTACACATTCCGGTGAGCGGCCATTTCAATGTGAGATTTGTTTGCGTAAATTCACATTGAAGCACAGCATGTTGCGGCATATGAAGAAGCATAGTGGACGCAGTCATAATGGTGATTTGGGTGCACAGTCTGATTGTTCCGATGATGAACAGTCTGCCACACCGCCTAGCACACCTACGCCCATGATAATGCCACaatcgaacaacaacaataacaataacaacaataataacaataacaatacttgccacaacaacaacaacaacaacaacagtaagcAAAGCTTGCGTCTGCCCAAATTGCATGAATTATTGGACAAGGCAAATGAATGGCGTGTCAGTCGTTTGGGTGAACACAAGGAAAACATTGCCGatgcatcaacaacaacaccaacagcagcaacagctgccgctgccgccgccgccgccgcagcagcagcagttgccagTGGCGATCTTATTGGCAATTTGCTAGGCATTAGCGATCAAGGTATACTCAATAAGTTGCTATCATCGGCAGATGAGGCAGCCAAGTTACTAGGCGtagaaaagtaa
Protein Sequence
MMLATQQQQQQHTSTTTAATAAAAAAATTTVAHSSDASDMDRQRRDSTTSESSLEHLDLGRTPKKLSSSNGAPQPTSTPHDTTTTTTTATSRKRKLRQQQQQQQQQHLHSDEDEEQQQQQQQQQQQLDQSAQRPRHKQRRSVNAAAAAASASIVVDYSASGDASSLRKKFRLNRSVGSGELSESGFVDGSANSAYLLSSSAGSSAQSASATANGAVAAAAAAAVAAQQASSSSSGGSSPQGLCLSSAESGIGAGDDHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQATQQQQQQQQQQSQSQQQQLSQSQQQSQSQSQQQQHTQRRQQHAATTVATQVTGRSESYESDASCSTDVSSAQSHSSSSNHSNNNNNNHKLSNNNNNNNNDEEEVENAATMCGKQRRHKININNNNIEEEQEEEEEHEEEEHDDDEDDNVAQLITSTPDVATLLASGDSTPNQMLLSCPACTADEFETLPALCQHLDAEHSDIPAKCRECDVIFASHRQLQMHSCAGSNGLQMLPLIGASSSPKHKQEIEDVLEEEEEDDEDEANAEADDLDMEQEQEQDHEMDQEQQLQHQQQQHQQHPAHKSDFFQQLYLKGKSNVIAPLPSPIKHELTDSRQDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSQYSLDGRDGEEEAQDAFTSEFRRMKLRGEFPCKLCAAVFPNLRALKGHNRVHLAAVGPTGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREEVKRAIVYHPAEDASCEDSKSGQRLQESELELSYRSVSPVEPASQLKHMLQAELPTTVAAAAAAVTAVKATPLKIQVKSLDQLVDKPLAPALDLSMDVLDLSKKPTAAQELQEQRERERERQHELLLCQQQQQQQQQQQQQQQVQQQQQQLFGAGDAATQYMQQLFRNLMFQQSPAFPFFGFMPPTTAGEQASTLPATVAAAAAAAAAAAGTGTPATSALTPATGGLSLPLPGVGVGVPVPAGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRAASSSTAAAAAAAAAAAAAAAAAAMSNLSQQQHGQHAHHAHISEQVKYAILAQQLKARKDTDLLQQALAHGSSSVAANSLLHFGYKQQQQLQQQHGSNMPAASNDDDEPKLIIDEDDEEEDDGLDEDEDELELDELELEQQQFEEQQQLDEQLEEQQQQQPARTSTPIEAAKKVAETILEQAIKAGKTTSDDCNNLPLKAAAAAATTTAATAATATATATTATATATTMKTLLAQAEAVAKSLKEVASSPFKDESPDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSSGNEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRERERERERQQLEREREQQQQRELEKQQREQREKEQQRQRELQMERQQQQQQQQQQQQQLMQQLAAAAQIVAACNATSATSPSPPAAAAACNNVESQASDLPYKCHLCEYSFGERLQCLEHIKQQHAQEYALLLSKGAIEMEEQQLSLSSLPLPPPPPPTTTATATVSDEETAARATTKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNGDLGAQSDCSDDEQSATPPSTPTPMIMPQSNNNNNNNNNNNNNNTCHNNNNNNNSKQSLRLPKLHELLDKANEWRVSRLGEHKENIADASTTTPTAATAAAAAAAAAAAAVASGDLIGNLLGISDQGILNKLLSSADEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-