Basic Information

Insect: Drosophila histrio
Gene Symbol: -
Assembly: GCA_958299025.2
Location: OY729167.1:19423223-19427332[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.16 12 6.8 7.5 2 23 339 361 338 361 0.96

2 17 2.2 1.8e+02 3.2 0.2 1 23 368 393 368 393 0.91

3 17 0.025 2 9.3 1.8 2 23 404 425 404 425 0.93

4 17 3 2.4e+02 2.8 2.1 2 17 436 451 435 462 0.78

5 17 0.021 1.7 9.6 0.9 3 23 495 515 493 515 0.96

6 17 0.007 0.55 11.1 1.1 1 23 523 546 523 546 0.97

7 17 0.17 13 6.7 1.6 2 23 551 572 550 572 0.96

8 17 0.00051 0.04 14.7 0.7 1 23 620 644 620 644 0.91

9 17 0.0049 0.38 11.6 2.4 3 23 651 671 651 671 0.92

10 17 0.0061 0.48 11.3 1.0 1 23 689 714 689 714 0.96

11 17 0.013 0.99 10.3 1.4 2 23 730 752 729 752 0.93

12 17 0.0011 0.087 13.6 0.5 3 23 759 780 757 780 0.92

13 17 0.032 2.5 9.0 0.5 2 23 784 806 783 806 0.95

14 17 0.00011 0.0088 16.7 2.7 1 23 812 834 812 834 0.98

15 17 0.0091 0.71 10.7 1.0 1 23 838 861 838 861 0.93

16 17 2.5e-05 0.002 18.8 0.5 1 23 867 890 867 890 0.97

17 17 0.00049 0.039 14.7 0.2 5 23 903 922 895 922 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.16	12	6.8	7.5	2	23	339	361	338	361	0.96
2	17	2.2	1.8e+02	3.2	0.2	1	23	368	393	368	393	0.91
3	17	0.025	2	9.3	1.8	2	23	404	425	404	425	0.93
4	17	3	2.4e+02	2.8	2.1	2	17	436	451	435	462	0.78
5	17	0.021	1.7	9.6	0.9	3	23	495	515	493	515	0.96
6	17	0.007	0.55	11.1	1.1	1	23	523	546	523	546	0.97
7	17	0.17	13	6.7	1.6	2	23	551	572	550	572	0.96
8	17	0.00051	0.04	14.7	0.7	1	23	620	644	620	644	0.91
9	17	0.0049	0.38	11.6	2.4	3	23	651	671	651	671	0.92
10	17	0.0061	0.48	11.3	1.0	1	23	689	714	689	714	0.96
11	17	0.013	0.99	10.3	1.4	2	23	730	752	729	752	0.93
12	17	0.0011	0.087	13.6	0.5	3	23	759	780	757	780	0.92
13	17	0.032	2.5	9.0	0.5	2	23	784	806	783	806	0.95
14	17	0.00011	0.0088	16.7	2.7	1	23	812	834	812	834	0.98
15	17	0.0091	0.71	10.7	1.0	1	23	838	861	838	861	0.93
16	17	2.5e-05	0.002	18.8	0.5	1	23	867	890	867	890	0.97
17	17	0.00049	0.039	14.7	0.2	5	23	903	922	895	922	0.90

Sequence Information

Coding Sequence: ATGTCGGAAAACTTGAAAACAAATAACGAAACTGGGCCTAGCTGCCTGCATTGCAGAGTGCACAATTCAAATCAAGTATTTCACGAGATATTCGATCAAGTGGGAATTGAAATCGAGCTACCCGAATTGCTGGCCAAATATTTCCACATTAATGTTAAAAAAGATGCaggaaaaaaacaattactgTGTGCCGAATGCGTTAAGACCTTAATACGTTTCTTTGACATTGATGAACTGCAGCGGGAACAAGATGCCGCCAAGGCTGCCAAAACTAAAAAGCAGGCCGCAATTGAAACAGCGCcgaaaactgcaactgcaactgcaagtgATGCTGACAAAAAGGCAACGAAATCTGATAAAAAACAAACGTCGCCCgctgttaaaataaatattgcacCCAAAAAGTtgacaacagctgctgcaaaGACTTCAACTTCAGCCGCTGCAAGAGATGCTGTTTCCACGGAGCCCGTTTCCGTACGCATCACCAGAGGAAGAACCTTGACTGTGACGCCGAAACCTCCGcaaattaaaactaatcaCAAGCCAAGTAAACGATGCAGTTCCAAGGAAGGCCGATCGGGTGAACAGCAGCAGATTTGCGAGCTCTTGCGCGATATACTGGATGACGAGAAGTCGCCACCCGATGATAAATTGACTGAGGCAGCGGAAACAGTGCGTCAATTGGAGTCACAAGTCGATGATGCGGAGAATCAATTGCAACAGGCGGAGGAGGGCGAAGATGAGGACGACAAACAGCAGGAAAATGCGGATGAGTTGGAGTTTCTGCTCGAGCATGAAGATGCTTCCTCCGATTTGGATGTGCGTCACTTTAAGGTGGAGAAACGTGGTTTAGTTGCGAACAATGACAGTCAGAGCGAGGCAGAATCCTTCAAAGTGGAGCTCATTAACTTTGTATTGATCAAGGAATCTGACAACATTGAAGATCTTTATGCATATCTGACAACTGTGGTGAAGACTTGCTTTGTCACCTTGAGCTTTGAATGGGCCACCGTGTGTTGTCACTGCTCGCTGAAGTTCAGCAAATTCGAGAGTCTGTTGGCGCACATGCAGAAGTGTCATCAGTTGCCGAAGGAACGCTTCAAGTGTCCGATTGCGAACTGCAATGCGGAGTTGCACAGTCGCAAGTATCTGGCCATGCATCTGGTATTGTTGCATGCTCCTGTGGCAGACATTCCCATTTATGGCAGTTGCCCCGAGTGCAACCTGACCTTCTCCAATATATTGCAGTATAATAAACATTCATGCGCTCACGTCATCAAGAAGCGTCGTGGCATTCGCTTGTATTGTGAAATGTGCGGCTTGGAGTTTCCCTCCTGGAAGCGCTTTAACTTTCACAGTCAATTCCATTTGGAGAAGCACCGGCCACGTGCTTGCTTTGTGTGTGACTATgcgaacaacaacatcgaagAACTCTTCCAGCATTTGCATTATTCGCATGAACCCGAAGGCACGCTCTTCTGTGATCTCTGTGATCGCAATTTCCGTGATGCTGTTGTGTTTGCTGATCACCACAAGAGCCATGTGAATCTCAACAACACCGTCTACACTTGCACCTCTTGTAGCGCCACCTTTGAGACTCGCGGACGTCTCTACAGTCATCAACGCGCCACACATGGATCCGCCATTAGCTGTGAGCTGTGCTGTCGGGAATTTGCCACGGAAGTCACCTACAACCTACACATGAAGAAGCATCTGATCATTGAGCGTGAGGTGCATGTGTGCAGCAATTGTGGCATTCTCAGTGAGAACAATGATAAGATTGTGAGTCACGTCGAGAATGTAGATTCGGATTGTTTTGGCGTTGAAATCTATTTGGAACTACTAAGGGATGCCTATGTTTGTGAATATTGTTCATCGTACTTTAGGCAGAAAACGGATTTGCAAGCACATCGCAATTCGGGCGTACATAAGGATGGTGTCTGTTGGTGTCAGCCGTGTGGCAAGTCATTTAACGACATGAAACTATATCGTCATCATATACGCAACCATCAGCAACTACGTAAGGATGTTGATCATCGCAAGCTGGAGATTTGTGTATACTTTATGTGCGACTATGAGGATTGCTTTGAGTCGTATGTCAATTGGAATTCTTTGTACACACACAAGCGACGCACTCACGATGCAGCTGAAATCCAGGTATCGAAGGCACAGGTCGATGAATGGATCTGTCAGTTCTGTCAGAAGGTTTGTCGCTCCAAAATGTCGCTATCGGTGCATGTGGCACGCAGTCACAACAATAATAATATAATTTGTCAGATCTGCAAGGCGTCCTACAAGGACAAGGAGGCGTTGACCAAACATCACGCCTATTGGCACGAGCCCATGGAGTGTGCACTGTGCCTGAAGAAGGTCAAGAATCGTCGCAACTTTGACACACACATGAATGTGGTGCATTCGAATAACAAGCGTTATTCCTGCAGTTACTGCGAGAAGGGATTCTATCACAGAAGCGAAATGGAGGCACATAAGCGATTGCATACACAATTGTATAGGTGCGAACAGTGCAGCTTCACTACGAAGAACAAGCAGTCACTGTCGGTTCATGTGCTCGGGCAGCATTACAAGAGTTTCGCCTTTGagtgcagcagctgcaataaGAGCTTTGGACGTCGCCAGGGCTTAGCCAATCATATGCAGCGTGCCCATGGCTCCAAGAATACGTGTCGTGATTTCTTTGATGGTGGCTGTAACAAATCCTTTGTCACAACCGCTCAGCTGAATGCGCACGTGCGCAAAGTACATAATAGCGGTGTATTTCTGGCCGATACTGTAgaggacgacgacgaagaGGGGGAGGACTTTGAACAGCCGGAcgaggagcaggagcagaaacagcagcagcagcagcagcaacaggaggaACGAAAACCAAAACGTAAGGTTTCAACCGAAGCATCCCCATCGAAGAAACGTTGTATTCGTATCAGCGACGATACACAAATCGAGTTCATTACTCCCGATCCCGAGGAGGATAACAAGAGCATTCCGGATTCGGATAATTGTGAGGAATTTCAAGAAACCAAATTCAAGGCGCCGCCAGCAAAACGAAAGAAGAAACAGAGTTAA
Protein Sequence: MSENLKTNNETGPSCLHCRVHNSNQVFHEIFDQVGIEIELPELLAKYFHINVKKDAGKKQLLCAECVKTLIRFFDIDELQREQDAAKAAKTKKQAAIETAPKTATATASDADKKATKSDKKQTSPAVKINIAPKKLTTAAAKTSTSAAARDAVSTEPVSVRITRGRTLTVTPKPPQIKTNHKPSKRCSSKEGRSGEQQQICELLRDILDDEKSPPDDKLTEAAETVRQLESQVDDAENQLQQAEEGEDEDDKQQENADELEFLLEHEDASSDLDVRHFKVEKRGLVANNDSQSEAESFKVELINFVLIKESDNIEDLYAYLTTVVKTCFVTLSFEWATVCCHCSLKFSKFESLLAHMQKCHQLPKERFKCPIANCNAELHSRKYLAMHLVLLHAPVADIPIYGSCPECNLTFSNILQYNKHSCAHVIKKRRGIRLYCEMCGLEFPSWKRFNFHSQFHLEKHRPRACFVCDYANNNIEELFQHLHYSHEPEGTLFCDLCDRNFRDAVVFADHHKSHVNLNNTVYTCTSCSATFETRGRLYSHQRATHGSAISCELCCREFATEVTYNLHMKKHLIIEREVHVCSNCGILSENNDKIVSHVENVDSDCFGVEIYLELLRDAYVCEYCSSYFRQKTDLQAHRNSGVHKDGVCWCQPCGKSFNDMKLYRHHIRNHQQLRKDVDHRKLEICVYFMCDYEDCFESYVNWNSLYTHKRRTHDAAEIQVSKAQVDEWICQFCQKVCRSKMSLSVHVARSHNNNNIICQICKASYKDKEALTKHHAYWHEPMECALCLKKVKNRRNFDTHMNVVHSNNKRYSCSYCEKGFYHRSEMEAHKRLHTQLYRCEQCSFTTKNKQSLSVHVLGQHYKSFAFECSSCNKSFGRRQGLANHMQRAHGSKNTCRDFFDGGCNKSFVTTAQLNAHVRKVHNSGVFLADTVEDDDEEGEDFEQPDEEQEQKQQQQQQQQEERKPKRKVSTEASPSKKRCIRISDDTQIEFITPDPEEDNKSIPDSDNCEEFQETKFKAPPAKRKKKQS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -