Basic Information

Insect: Drosophila histrio
Gene Symbol: -
Assembly: GCA_958299025.2
Location: OY729166.1:7656232-7658484[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0038 0.3 11.9 7.4 3 23 223 243 221 243 0.97

2 12 0.00061 0.048 14.4 3.8 1 23 249 274 249 274 0.95

3 12 0.00044 0.035 14.8 0.7 1 23 281 306 281 306 0.96

4 12 0.0017 0.14 13.0 3.5 1 23 314 336 314 336 0.97

5 12 0.00011 0.0085 16.8 0.9 3 23 345 365 343 365 0.98

6 12 1.3e-05 0.001 19.7 0.2 1 23 371 393 371 393 0.98

7 12 0.61 48 5.0 7.5 1 23 399 422 399 422 0.98

8 12 0.036 2.9 8.8 5.7 1 23 428 450 428 450 0.94

9 12 7.9e-05 0.0062 17.2 2.0 1 23 456 478 456 478 0.99

10 12 9.9e-06 0.00078 20.0 0.3 2 23 559 581 558 581 0.96

11 12 0.00041 0.032 15.0 4.7 1 23 587 609 587 609 0.96

12 12 0.00077 0.061 14.1 6.1 1 23 615 637 615 637 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0038	0.3	11.9	7.4	3	23	223	243	221	243	0.97
2	12	0.00061	0.048	14.4	3.8	1	23	249	274	249	274	0.95
3	12	0.00044	0.035	14.8	0.7	1	23	281	306	281	306	0.96
4	12	0.0017	0.14	13.0	3.5	1	23	314	336	314	336	0.97
5	12	0.00011	0.0085	16.8	0.9	3	23	345	365	343	365	0.98
6	12	1.3e-05	0.001	19.7	0.2	1	23	371	393	371	393	0.98
7	12	0.61	48	5.0	7.5	1	23	399	422	399	422	0.98
8	12	0.036	2.9	8.8	5.7	1	23	428	450	428	450	0.94
9	12	7.9e-05	0.0062	17.2	2.0	1	23	456	478	456	478	0.99
10	12	9.9e-06	0.00078	20.0	0.3	2	23	559	581	558	581	0.96
11	12	0.00041	0.032	15.0	4.7	1	23	587	609	587	609	0.96
12	12	0.00077	0.061	14.1	6.1	1	23	615	637	615	637	0.98

Sequence Information

Coding Sequence: ATGAATGAGGAGACTGCACCCTCTATACATTCAGTGTGCCGCACTTGCTTATCCAACCTGCAGCAAGATGAAGCCTtcgatttgtttgttgtgcccGGCCTGGCCAagaaattgtgtgtgtgcacttcCCTCTCCGTGGAGCACCTCGATGGATTCCCCAAAAACCTCTGCAAAACTTGCAACACACGTCTTAACGACTTGCACGAGTTTCAAAAACAATGCGTAGACTCTGTACAAAAGTTCAAGGAGTTGGTATCCAAGAGCTGCTTCACAATCCGAATGATTCCAGAGGTCGATGCTGCCGTCTATaatgctgctgatgttgagGAGGAACACATCAACTTTGACCCACTGCTCAGTACCAAAATAGAGGTTGACAATGAGGAGgatgtaattaaaatgatagAAGATGTCGACAAGGAATCTGAGGTAGATAATTTGGAGGAGGCGTTCGATGAAAGCGGCAGCGACTATAACAACGAGGATGATGACTTCGGAACAGTGGAGAGCAGCGAGTCCGATGATGAATTGCCGCTGTCACGCCTACGATCCACAACAAGAGCTGCAAGTACCAAGACCAAACAGACGGATAAAGATGAACCTAAGCAAAAACCGAAGCGTAAACGTATTCCGGCAGCTGAGCGTGATCAGCATCGGTTAATCGACTGTCACATTTGCCATCAGAAGTTCAAGAAGGCAGTCTGTTATGAGAAGCACATGAAACGCCACAATGATCAATTGCCTTTTCAGTGCACAGCAAAGAAATGCCAGCGGGGATTTACGACTTCCACTGGTCTAAAACATCACATGGAGCACGCTCACTCGGAACTGTGCGAGCTTCATCGGTGCACAGTGGAGGGATGTGAGGAGGCATTCGCACAAACTCGCCTGCTCACTAAACATCTGCGCAAGGTGCATAATATTGCCAAGCCTGAAATCCATCCATGTTCAGAATGCGAGAAGGTATTCCGTTGTCCCATGGCGCTGAAGAAACACATGTACAAACACACGGGCGAAGAACTTCCTTTCGGCTGTAGTGTCTGCAACAAACGCTTTCGGGTTAACACTGAACTTCGGGATCATCTTTTACGTCATGCTGGCATCAGGAATTTTGTTTGTCCCTATTGCGGTGTTGGCAGAACGACGAAACAGGAGCTGGAGAAACATATACAGACGCACACGAAGGAGAAGAAGTTCAAGTGCGATCAGTGCGAGCACACGTCGCACAACAAGCAATGCATGACGAAACACATCAAGGTGGTGCACATGAAGATCAGGGACTATTTATGCCAGTATTGCCAAAAGTCCTTTGCCAGCGCCTATCACTGCAAGAACCACGAGAAGTTGCACACTCGTAATGATTGCTTTGAGTGCAAGATATGTGGCAGGAAATTCCTCTTCGAGAGCAGATTGACAAGACATTTAAGGACGCATGAGAAGCGTGGTAGTAAGTCCGCTGCAATCGCTACAAAGCAGGAACCAGATGCGGAGGTACAGGAGGAGGCGACGTTGACGGAACCAGCAAAAGTACCAGTAAAAGTACCAAGGGATCCCCGTCGAATTGAAATTGTGGATATATCTCAGTTGGCCGGCACTGTCGTCAATCCCATTCCGTCGGTATCTGTGTCCTCCTGGTCGCCGCAAGATAATTTCACCAAAAACGATGGCCAGATCGAGTGTCCAGAATGTGGAAGGAGTTTCAATCACGTCAGCAATATGAGACTCCACGTCAAGGTAGTGCATGAAAAGGTCAAGGACTACGCCTGTCGCTTCTGTCCGAAGCGCTTCAGCAGATCTCAGTATCTCCGTCATCACGAGTACACGCATACGGGGGAAAAGCCTTACGAGTGTAAAATATGCCATCAGCATTTCAGACACGATGCAACATTGGGAAGACATATGCAATCTCATAACAAACCTCCAAAGGAACACAAGAGACCAGGCAGAAAGCCAAGAGATCCTCACGAGCCCAGACTAACACTGAATACGGAACCTGTTATGAACTATGAACAGTATCTGGATCCAGATGCCGAGCGGGAAGCGGCAACGGCCGAGTTGATGGCCCAACAACTTAGGGAGGGCGAGCCCAAGCCCAAGTGGGGACTGGCCAAAAGTCAGGAGATCCAGGAGGCAGCTTTCGAGCAGCTGCAAAAGTTGCGGGAGAAACAACTAGAAAAGATTTCCTATGATAGCTTCGCTGACCAAGCCGGCGATTTGGGTGTTAACAAGGATATTCTCAAAAATCATGTATAA
Protein Sequence: MNEETAPSIHSVCRTCLSNLQQDEAFDLFVVPGLAKKLCVCTSLSVEHLDGFPKNLCKTCNTRLNDLHEFQKQCVDSVQKFKELVSKSCFTIRMIPEVDAAVYNAADVEEEHINFDPLLSTKIEVDNEEDVIKMIEDVDKESEVDNLEEAFDESGSDYNNEDDDFGTVESSESDDELPLSRLRSTTRAASTKTKQTDKDEPKQKPKRKRIPAAERDQHRLIDCHICHQKFKKAVCYEKHMKRHNDQLPFQCTAKKCQRGFTTSTGLKHHMEHAHSELCELHRCTVEGCEEAFAQTRLLTKHLRKVHNIAKPEIHPCSECEKVFRCPMALKKHMYKHTGEELPFGCSVCNKRFRVNTELRDHLLRHAGIRNFVCPYCGVGRTTKQELEKHIQTHTKEKKFKCDQCEHTSHNKQCMTKHIKVVHMKIRDYLCQYCQKSFASAYHCKNHEKLHTRNDCFECKICGRKFLFESRLTRHLRTHEKRGSKSAAIATKQEPDAEVQEEATLTEPAKVPVKVPRDPRRIEIVDISQLAGTVVNPIPSVSVSSWSPQDNFTKNDGQIECPECGRSFNHVSNMRLHVKVVHEKVKDYACRFCPKRFSRSQYLRHHEYTHTGEKPYECKICHQHFRHDATLGRHMQSHNKPPKEHKRPGRKPRDPHEPRLTLNTEPVMNYEQYLDPDAEREAATAELMAQQLREGEPKPKWGLAKSQEIQEAAFEQLQKLREKQLEKISYDSFADQAGDLGVNKDILKNHV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -