Dhis010997.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila histrio
Gene Symbol
hang
Assembly
GCA_958299025.2
Location
OY282582.1:25964485-25982293[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.41 32 5.5 1.0 3 23 643 664 642 664 0.93
2 18 0.3 23 5.9 3.5 3 22 771 790 769 790 0.89
3 18 0.00088 0.069 13.9 3.3 1 22 892 913 892 915 0.90
4 18 0.1 8 7.4 0.1 2 21 927 946 926 947 0.93
5 18 0.001 0.08 13.7 0.2 2 23 1077 1099 1076 1099 0.95
6 18 0.0029 0.23 12.3 0.1 1 23 1107 1130 1107 1130 0.96
7 18 2.4e-05 0.0019 18.8 0.1 2 23 1216 1237 1215 1237 0.97
8 18 0.00042 0.033 14.9 2.9 2 23 1346 1368 1345 1368 0.97
9 18 0.033 2.6 8.9 0.2 2 23 1377 1399 1376 1399 0.95
10 18 0.0032 0.25 12.1 0.1 1 23 1412 1435 1412 1435 0.97
11 18 0.00018 0.014 16.0 1.1 1 23 1481 1503 1481 1503 0.99
12 18 0.0029 0.22 12.3 0.9 1 23 1511 1534 1511 1534 0.96
13 18 0.1 7.8 7.4 0.4 2 19 1542 1559 1542 1560 0.94
14 18 0.00011 0.0083 16.8 0.4 3 23 1663 1683 1662 1683 0.98
15 18 0.0074 0.58 11.0 0.1 1 23 1718 1740 1718 1740 0.97
16 18 0.00087 0.068 13.9 0.6 2 23 1835 1857 1834 1857 0.93
17 18 0.0094 0.74 10.7 0.3 3 23 1913 1933 1913 1933 0.98
18 18 4.4e-05 0.0035 18.0 1.3 1 23 2368 2390 2368 2390 0.99

Sequence Information

Coding Sequence
ATGGTGCTCTCACAGCTCTCGGTTATTGATTCTTTCATTTGGCAGCAGGGCACAGCTGAGCCTGCCAGCAGGCAACCAACCAAGAAAGCAACCAACCAAGCAGACAGGCATGCAGTCAAACCCAGAGCAGAGTCGCCCTCGTCATCCACTTTTCGTTCGGCATTGGCAGGCACAAAATGGTTGCCTGCTTGCTGTTGCGACTCTTTGGCCTGCGCCCCCGGCAACGACATCATCATCTACGTCGTCGGCGTCGGCACGTTGCTGCTGCGTGTGCTTGGTGCTGGCACTGGGCTGCTCTTTGGTTTCGCTTTGGCTCGATTTCATGAGGCCGAAACTCGTTCAGTTCCCCGAGATCATGCGGCGTTGCTGGACAGGCTGTGCCTGAGAGGCACTTTAATTCTGGCCAGCATCTCAGTTTTGTGGCATCATGGCGGCGCTGATGATGATTGTTGCACCTGGTGGCCAGCAATGGCAGCTGgcaacagcggcagctgcTTCTGCatgttgttggtggtgttggCGTTGGTGTTGATCACGTCATTGGATCGCCTGTCGCTGAATATTTGCCATGCCTGCATCAGCTATTTGAACTCCTGGCAGAGCTTCAAGAATCGCTGTCTGAGCTCACAATCGAAGCAGCGCCAATGGCTGGATATGGACAGAACCAAGCAGCAAACACTATTGGGCTATTTGGATTTGAATCGGGCCGAGAATGGCAGCATCGttgatcaacaacaacaacaacagcagcagcagcaatccgAATTGAAAATCGATACGGCGACAACTGCAGCTGAGAAGGCATCCGCCAACATTTTGGATGGCATTCCCTCGTTGAAGAAGCGCAAATCGTTAACAGTCTATGTGAGTCCAAAGCAACAgcttcaacagcaacaacaacaacaacagcagcagcagcaacaacagcagcagcagcaacaacaactattacTGCAAACGGCTAGAACAATGAGCGCGGCAGCGGAACCACAGCAAACATTGCAGAATCTTTTATTGCAGGTGCCCGCAAcggcggcaatggcaacgatatcagcacagcagcaacatcatcagcagcagcaacagcagcgcaaatatcagcagcaacatcgtggcaagcaacaacagcatcatcaccatcatcattaccaacagcaacatcatcaacattatcatcatcaacaacaacagcagcaacagcagcgacataGACGCATTCGTCAGCAACGACGACAGCCGCAacaggcggcggcggcaactgTTGTTCAGCGTTTGCCCAAATTTAAGCCAAAAGTATACTTGCCACTTGACATTGCAGTGCCAGCGCTGCCGCCACTGCTGCCGACAtcgactgcaactgcaactgcgactgctgctgctgcaagtgTAACTGCAACctcaactgcaacagcaactgctgctgttgctgttactgctgctgttgaggcAGCTGCattattgccattgccattgccgttgtcGCAGCCAATTGATTTCAGTCAGAGTCAAATTCAAAGATATGGCAGCGGTATATTGCCACCGCCAACTCCAGTTGCCACAATGACCAGTAACAACGTCGAAACTGCaacatctgctgctgctgcgtctgcCGCTGGCTCAGtctctgccactgccacagccACAACTCCGCTGCTTATGCCGCCGCTGCCCGCCGTGCCCATCAAGGATGAGCCGCTGGACGACACGGACGATGACTTTCAGATGAAGTGCATTGACGAGTCCGATGACATGATGGATCCCACAATGTTCCTAGAGCGCTCCGAGCACGAGGGCGATGTGCCGCTAATGACCTCCGACTATGATTACACGGCGCAGCACGGCGTGACTGcggctgtggcagcagcaTCGCTGCCGGCAACCGCTGTGGCAAATGTGGCAGCCGCTGGGGACTCAAAGGTGGCAAGTTGCCGTGCCTGCAGCCTGCAGTTCTCGACGCGAGCGAATGCTCGACGACATGAAAGGAATTTGCATCCGAATCTGTTTCAATTGTCAACAGACTCGCCAAATAATACGCCAATCACAAAACCGACGCCGGCATTGGCCGCCGCCCTGGAAATTCAGCGTGCAGCAGccgcggcagcggcaacagcggAGGCAACAAAAGCTGCAGCTGGTGGCAATATATCGACACAGAAATATCGCCAGGTGGTGATGAACACGTTCATCAAGTGCGAGAACGGTGGCTATGACTATGACAATCCCGAGCAGTATCAACAGCTGTTGAGCCGTGATAAAGTCTTGTTTATACAGGAGAACAACGAATTTCTTGAGCAATATCAGACGATGACGTGTCGATGTTGTAACAAATTCTTTAGCACCTACAAGAACTTTATGGCGCATGTGCGTAAAAAGTATCCACTGTTGCCACGCAATCTGTGCTTCAATTGCCTCAAGATGAACGATTCAAAGGCGTTGTTCATATCGCATTTGAAGAAACGCAATTGCATCAATTTGTATCGTGTGCTGAACGCGTTGCGTCTAAAGCAGCCAAATTTTGCACATGCCACAGCAGCCGGTGTGGTTGCAACAACAGAACAGCAACAggaccaacagcagcagcagcagcaacatttgatGGTTACTGCACACGAAACGTCGTCATCAGAGCGACCAGAGAAGTTGCGTGCCAAGGAGTTGCTGGTTAATAAACTGTACGAATGTAAACTCTGTCCAAAGGGATTTCGGACGAAGCACGAGTTCCGCACACATGTCTATGATAAGCATGCGGATGTCCAGCGTAAGGATAACAATTCGATACAGTGCAGCTTCTGTGGTTTAGACTTTGCCGATCCCGTTGACCGGCGACGTCACTACAACAACATGGACTGCATTGTCCGTCTGCGCTGCATGACCTGCGATGCCAAATTGGAGACGCATCAACGTTTCCTCGATCATGTCTATCAGGATCATTTGGGCGGTGTTAGCAGTGACAATGCCTCGACCGTTAACAGTGGAATGGATCATTCCCCTGGCAAGCGGAGTCTGCTCGGTGCCCTGGGCATCGGTGTCAGTCAATCGTCCAATGATGAATCACgctgcagtagcagcaataATAACATTGCAGGCGGCGGCAGCACACCGTTAACCTCAACGCCAAAGctgacgacaacaacatcagcgGCCGGTGGAGCGACTGCGACAAGTGGAGGTTCCGCGTCCGGCAGTCGTGATGCCCCCAAATCCCAGTATTTCTCCCGCATGCCACAGGTCTGCCCCATTTGTGGCCAGCAGTATAATAACTATAACAATGTTCTGCGTCACATGGAATCGAAGCATCCAAATAAATTGCCCGAGACATATAAGTGTGTCCGATGCGGTTTGGGCTATCCAAGGATCTCATATCTGCGCGAGCATATGATCAATGTGCATGGCGTGGACAAGAATCGTCATTCCGGCGGATTTGAGTATATTGTGAATGCGGATGCGGTTAAATTGGCCGATGGCAGCACACCAAATGTCTATACCGGACGCTACGATTATGTGATGAAGGATCTGATGTCCATAACAAATGGTGGGACACTCgatgatgatgacgaggaAGGCGGCAGCATTGCCAAAAAGATGCGACTcgacgacagcagcaacaacagcagcatcaacacAACCATCGCCAACCAGCAAAAGGAGTGTCCCATTTGTAATGCCGTGTTTAGCAATAATATTGGACTATCGAATCATATGCGTTCACATTACACGGCCTCAACGACGGCAACAAATGCAGCTTTAGCGGCTGCCAATCGCATGACACCCAAATCGTTGACAATTACAGCAACGCCGCCACTTGAGGTGACAGCGGCCACATcgacagcaacagttgcaacatcGGCAACATCTTCCTCCACAGCTGCAgccgctgcagcagcagcaacaactgtgaCACCAATAAGcacaacaagtgcaacaacgTCGGCGACAACAAAAGTGCCACCGGCAATGGTAAATCAAACGCCACAGGAACAGGCCGTATTCCGCCGGAGTTTAGATCAAGCGGCAGATCGTCGCTTTCGTCGGATGCGCTGTCGCATCTGTCAGCGTAGATTTAGCTCGAAAAAATCATATCGCTATCACATGCTGACCGATCATCAGGTGCAGAATGTGCAGTTTATCAAATGCAAACTGTGCAACGCCGAGTTTGCCTACGAGAAGGGATTGAAGGTGCATCTGTTTAAGGTGCACGGACGTGCCATCAAAGATGAGATGATAATCAAGCAATTTGAATGTGATGTCTGTTCGATTGTCTACAGCTCAGAGCTGGAGTTGCAACAGCATAAGCGCAGCGTTCACAAGTCACAATTGGGCACCGATGCGATGAAATCATCAATgaaatcatcatcattatcatcaacaACAGCTACCGCTACCTCTGCTGACCTGGCCGAAACATCCGGCAGTGCGTTGGCCGTCCTGCCATTATATTGGTATCAGTGCAAGTATTGTCCATCCAATTTCAATACGAACAAAAAGCTGGCCATTCACATTAATTCCCACGATGAGTTCGATTCCAATGATTATTCCTGCAAGGATTGCGGTAATGTCTACAGCGGACGCAAGAGCCTCTGGGTGCATCGCTATAAGAAGCATCCGCAGGTGCCGGATCCGGCGGAGTGCACGCTGTGCCGCAAGATGTTCTTCGATCGCCAGATGCTGGAGAATCACACGCCCACCTGCAATCGTAAGCCTATTACGGCAACTGGAGCACATCAACAggatcaacagcagcaacaacaattgcaactgcaacagcagcgtgGCATTTTCAAGCATAAAACTGGcgatgatgacgacgaggaGGACGATGAcgagcagctgcaacaacatcaaatgaTGTtggatgatgctgctgctggtggtggcAATATTGCAAGTGACGGCAGCAACGGTGGCAACACCGTATCCGCTGTCACaggcaataataaaaacacaatcAGTACAAGCAGCTTAAAGATTCGCATACCCGAAGTTGCGTGCACCATTTGTGGAGCTCGTTTCACTGACCAAGAAATGTTCAGCAAGCATATACAAAAGCATGAACAAGAATTATATGTGGACAATCCATTGGCAGCAATGTTCGATGATGGTCCGGCGGATGCGGGACAATTTCAGGTTGAGcggcaaaatgaaaatggggAATATGCGTGCGATTTGTGTGCAAAGACGTTCCCCCAGGTGATTGCGCTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAATCTCATCATCGACGGCGAAGCGACAATGctgaacaacaacaccaacaacaacaacaacagcagcagcaacaactcgaTGTTGCATCTGCGAGAATTGCATGCGGTGGGTTTGATGcccaatcaacaacaacaccagaagcaacaacaacagcagcagcagcaacaacagtcgcagcaacaacaatcgagcaacagcagcaacaacaacaacagcaacagctcaTCGACCAGCAAATCGATGAAACGGAAACGTGAATTGAAATGCGAATATTGTGCCTCAACATtcattagcaacaacaatctgcGACGTCACATGTACGAGTTGCACAAACATGAGGTCAGCAATCTACCCGAACCGCCAGTGATTGAAGTTGATGAACCGTTGTGTTGTCGTCGCTGCGGTGATTTGCATTTCGAGACAAAGGAATTGTGGATCGAGCATAAATTGGCGGACGCAAAGGTGGTGCGTCCATTTTGTCCATTCCAATGGGGCTGTGATCTTTGTGGCGAATATTTGTCGCGCAAGGAGAAGCTAATCAATCATATTAACAATCATCTCAAGGAGGAGGTGATTGTGCCAGTTGCAACCGCAAAGATAACTGTAAatgcgacagcagcagcggcagccgaaacaacaacagcagcagcagcaacatccggcaacagcagcagcacaacgacgacgacagcaacaacagcagcaacaaaggcagcagcaacaacagcggcagccgcagcagcagcagcaacaacaacgccagcaACACTTGGCAAATCATTAAAAGCCAAAATGAATGAAAGTGAAAGAGGTGAAAAGTTGAGCAAAGTGCGTGTAGCAAATGTTAATGTGGAGGAAGAGGATGATAGTGATATGGATGATGATAGCGAtagcgatgatgatgatgatgatgacgaggatgatgacgatgatgatgaggatgatgacAGCACaagcgatgatgatgatgatgaggacgacgacgatggaGACGATGAAGAGgaagatgttgttgttgcacagcagcagcaacagcagcagcagcaacacaatagcaacaatgatgaggatgatgatcTCATTGAGGAGGTTATCGAAGAGattgacgatgatgatgatgatgccgatgcagttgcagttgaacaacatgttgttgccacatcgaacaacaacaaagttaactttaattatGCACGCAAATTGAATGGCAATGGTGGCAAGAAGACAAAGTTGCAAGCAACGCAAATGCTCGTTGTGCATAGCTCcgaggaggaagaagaagaagtcgaTGATGATGTGGAAATGGGCGAagatgaggaggaggaagaggaggagatGGGTGTGGGAGTGGGTGAAGTAATGACCATTGATGATATTATTGAGGAAGATGATGGTGAAGATGATGAAGACGATGTGGTTGGTGTTGATGGACATGTTgttgaagatgatgatgatgacgacggcgacgatgatgatgatgatgatgatggggtggaggaagatgatgatgatgttgatgaggaggaggaagaagatGTTGATGAAGACGACGAATTGGGCAATGGGCGTCGTCGCAATCGTGTTGTCGTtcatgatgacgatgacgatgctGATATGgatgttgatgatgacgatgatgatgatgatgcgcgtcgtcgtcgtcatcatgtCAACATTGCCGATAATGACGCTGACGGCGATAATGATGGGAATGTTGATggtgataatgataatgatggtACATCATCATCCGAGAGCGagtcgacaacaacaacctcgCAATCAACTGGTGAGCGGCGTAAAAAAACTGTAGTTTCATCAGCGGCACATGGCGCTGCCGCTGATCAGTCTAATTCCAGCTATACGTGTGATCTATGTCAACTTTGTTTCGATTCTCAGGAGCTTCTGCAAGCGCACATTAAAAGCCATTTTGTCAATGGACCAACGGCGGGcagcaagagcagcaacaatggcagcaacaacagcagcagaagcaacaataacaatagtaacaacaataataaaagcaaaaccaaAAAGTCTGGCCTGTTGGATGAAACAAAAAGTGTCAGTGGTGGCAgtgcaacaacgacaacagcagcagcagcagcaacaacaacaacaacatccacagcagcagcaacaacagcggcagcatcgacgtcgacgtcaacgtcagcaacgactgcgacagcgacagcggcagatGCTGCTGCGAGCTTGAACTGA
Protein Sequence
MVLSQLSVIDSFIWQQGTAEPASRQPTKKATNQADRHAVKPRAESPSSSTFRSALAGTKWLPACCCDSLACAPGNDIIIYVVGVGTLLLRVLGAGTGLLFGFALARFHEAETRSVPRDHAALLDRLCLRGTLILASISVLWHHGGADDDCCTWWPAMAAGNSGSCFCMLLVVLALVLITSLDRLSLNICHACISYLNSWQSFKNRCLSSQSKQRQWLDMDRTKQQTLLGYLDLNRAENGSIVDQQQQQQQQQQSELKIDTATTAAEKASANILDGIPSLKKRKSLTVYVSPKQQLQQQQQQQQQQQQQQQQQQQQLLLQTARTMSAAAEPQQTLQNLLLQVPATAAMATISAQQQHHQQQQQQRKYQQQHRGKQQQHHHHHHYQQQHHQHYHHQQQQQQQQRHRRIRQQRRQPQQAAAATVVQRLPKFKPKVYLPLDIAVPALPPLLPTSTATATATAAAASVTATSTATATAAVAVTAAVEAAALLPLPLPLSQPIDFSQSQIQRYGSGILPPPTPVATMTSNNVETATSAAAASAAGSVSATATATTPLLMPPLPAVPIKDEPLDDTDDDFQMKCIDESDDMMDPTMFLERSEHEGDVPLMTSDYDYTAQHGVTAAVAAASLPATAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAAAATAEATKAAAGGNISTQKYRQVVMNTFIKCENGGYDYDNPEQYQQLLSRDKVLFIQENNEFLEQYQTMTCRCCNKFFSTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNALRLKQPNFAHATAAGVVATTEQQQDQQQQQQQHLMVTAHETSSSERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVSSDNASTVNSGMDHSPGKRSLLGALGIGVSQSSNDESRCSSSNNNIAGGGSTPLTSTPKLTTTTSAAGGATATSGGSASGSRDAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDDDEEGGSIAKKMRLDDSSNNSSINTTIANQQKECPICNAVFSNNIGLSNHMRSHYTASTTATNAALAAANRMTPKSLTITATPPLEVTAATSTATVATSATSSSTAAAAAAAATTVTPISTTSATTSATTKVPPAMVNQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIIKQFECDVCSIVYSSELELQQHKRSVHKSQLGTDAMKSSMKSSSLSSTTATATSADLAETSGSALAVLPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECTLCRKMFFDRQMLENHTPTCNRKPITATGAHQQDQQQQQQLQLQQQRGIFKHKTGDDDDEEDDDEQLQQHQMMLDDAAAGGGNIASDGSNGGNTVSAVTGNNKNTISTSSLKIRIPEVACTICGARFTDQEMFSKHIQKHEQELYVDNPLAAMFDDGPADAGQFQVERQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNLIIDGEATMLNNNTNNNNNSSSNNSMLHLRELHAVGLMPNQQQHQKQQQQQQQQQQSQQQQSSNSSNNNNSNSSSTSKSMKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIEVDEPLCCRRCGDLHFETKELWIEHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLINHINNHLKEEVIVPVATAKITVNATAAAAAETTTAAAATSGNSSSTTTTTATTAATKAAATTAAAAAAAATTTPATLGKSLKAKMNESERGEKLSKVRVANVNVEEEDDSDMDDDSDSDDDDDDDEDDDDDDEDDDSTSDDDDDEDDDDGDDEEEDVVVAQQQQQQQQQHNSNNDEDDDLIEEVIEEIDDDDDDADAVAVEQHVVATSNNNKVNFNYARKLNGNGGKKTKLQATQMLVVHSSEEEEEEVDDDVEMGEDEEEEEEEMGVGVGEVMTIDDIIEEDDGEDDEDDVVGVDGHVVEDDDDDDGDDDDDDDDGVEEDDDDVDEEEEEDVDEDDELGNGRRRNRVVVHDDDDDADMDVDDDDDDDDARRRRHHVNIADNDADGDNDGNVDGDNDNDGTSSSESESTTTTSQSTGERRKKTVVSSAAHGAAADQSNSSYTCDLCQLCFDSQELLQAHIKSHFVNGPTAGSKSSNNGSNNSSRSNNNNSNNNNKSKTKKSGLLDETKSVSGGSATTTTAAAAATTTTTSTAAATTAAASTSTSTSATTATATAADAAASLN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-