Dhis006110.1


Basic Information
Transcription Factor Domain
Sequence Information
Similar Transcription Factors

Basic Information

Insect
Drosophila histrio
Gene Symbol
-
Assembly
GCA_958299025.2
Location
OY282581.2:22608481-22613077[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 25 0.0017 0.14 13.0 2.0 1 23 208 230 208 230 0.96
2 25 0.09 7.1 7.6 1.3 2 23 290 311 289 311 0.96
3 25 0.0094 0.74 10.7 1.1 1 23 386 409 386 409 0.94
4 25 4.5 3.5e+02 2.2 6.3 2 23 420 443 419 443 0.93
5 25 0.083 6.5 7.7 1.1 1 23 449 471 449 471 0.97
6 25 0.068 5.4 8.0 2.3 2 23 490 511 489 511 0.97
7 25 2 1.6e+02 3.3 1.0 1 23 586 608 586 609 0.92
8 25 0.02 1.6 9.6 0.4 1 22 618 639 618 639 0.95
9 25 0.046 3.6 8.5 8.0 1 23 648 670 648 671 0.95
10 25 0.00021 0.016 15.9 0.3 2 23 698 719 697 719 0.97
11 25 2e-05 0.0016 19.1 5.4 1 23 727 749 727 749 0.99
12 25 0.16 12 6.8 1.0 1 23 899 922 899 922 0.95
13 25 5.4 4.3e+02 2.0 1.8 2 20 930 947 930 950 0.70
14 25 0.055 4.3 8.3 0.8 1 23 959 982 959 982 0.93
15 25 1.1e-05 0.00089 19.9 1.9 1 23 1007 1029 1007 1029 0.97
16 25 0.00014 0.011 16.4 0.9 1 23 1036 1058 1036 1058 0.98
17 25 0.0023 0.18 12.6 0.0 2 21 1085 1104 1084 1105 0.93
18 25 0.096 7.6 7.5 4.0 1 23 1150 1173 1150 1173 0.96
19 25 0.021 1.6 9.6 0.3 1 23 1210 1233 1210 1233 0.96
20 25 0.001 0.079 13.7 3.5 1 23 1258 1281 1258 1281 0.97
21 25 1.4e-05 0.0011 19.5 0.1 2 23 1304 1325 1303 1325 0.95
22 25 0.00017 0.013 16.2 2.9 1 23 1331 1353 1331 1353 0.99
23 25 2.4e-06 0.00019 22.0 2.0 1 23 1359 1381 1359 1381 0.97
24 25 6e-08 4.7e-06 27.0 2.4 1 23 1387 1409 1387 1409 0.99
25 25 0.00072 0.057 14.2 0.3 1 21 1415 1435 1415 1439 0.91

Sequence Information

Coding Sequence
ATGTTGCCGACCAACATATGCCGCACATGTGCGCTACACgatataaatttgttggcgCTCTCAACGCGTACCGagaaatatgcaaacaaaagTTTCTGTGACATGTTGCATGAATTAACACAAAACGATCCTTTAATGGAACACTCAGATGATAATTTGCCCCAGTATTTGTGTGGCGACTGCTTGCGTAAGCTGGAAGATGCTTACGCATTTGTGTTGCAAGCACGGAAGGTTCAAGAGGAACTGTTGCACAAAATACACAAAGGATTGCAGTGTCTGGATGAGACACCTATAGACATCGCCACCCAGCACATAAAATCAGAATCCGACGTTGCCTTGGAGCTAGTAAAGAATGCAGCAGATGAAATTGAAGCTGTGTCGGTTTTAGCTTTAAAGTTGCAGCCGGAGAGTGAGACCGACAGTAGCCAGGCAGAAGTGGCTGAAGAGGATGTACTAGACTTTAAGCCCACGCAGCTGAGACGCAGCAGTCGGAGGGCAAAACTTACCACAGACAGCGAAAATGAAGCGACTGCTGAAGATTCAAGTGCAATGCCGCTCAAGCGTCGTCGCGGTCGCCCAGCGCGTGTTCCTAAAGGGGAAGCTATCAACCAGGACGGACGTCATGCCTGCGAGGTGTGTGGCAAGACGTTTTCGTGGCATCGCGACATGCAGCGCCACGCTCGAGTGCACTTCGAGCAGGCCGGCCACGTTTACGACAGCTGTGGCAAGGGATTCCTTCGCAAGGACAAGTATGTGTTCCATTTGCGGTCGCACGAGAAGCGCCAAGCTAAACAGGACGCTCTACAGCTGGGAAACGAGTGGCGCTTTGCGGAACGCCTCTACAGCCCTGGGCGCCTCAAGCGTGTTGAGTGCAAGTTGTGCGGCTTGAAGTGCCAGCGAATTCAGGAACTTCGAGAGCATCTGACTAGTCATGTCAACATTGATACTCTGTCGAATCTTAGCGCCAATAGCGATGTTATCGTAGAACAGTTTGCCAGTCATCAACTAGAATTGATGCAGATTAAGCAACAAGTGTGTGCGGATATTGCTAAGGGAAGCGAACACCTAGATAAATACTGTGTTGTTGTCAATGCTCATGGCTATGAGCTCTGCCTGAGCGACTCGGACGAGGAGTTAGCTGGAGTACCGCCTCCTTACCAATGCCTGCTCTGCAACACGCTCTTCTCCCGTAAATATCGCCTTATAAGTCACACACTGGAGATGCACACTCTGCCGAAAACCAAGACATCTTGGCAACGTTGCAATCACTGTCAAATTGGCTTTGTATGCGAAAAGCTGCTGGAGCAGCATCAACGCACTCAGTGCCACAATCAGTTGAAACGTTATAGTTGCCCCAACTGTCCAGGCAAATTTATTTGGCGGCAGAATCTCAAGCAGCATGCGTGCTCCCATCGCATGCAATCTTCAGATTCACAGGATCGAGAGAGAAGTCAAGGGCGACAGATTCAGTGTTGCCTTTGCGATGAGCACCTGAAAAGTATGTCAGCACTACGTTCTCATCTAGTCACCCATTGTGACGGACAGAGCGGCATTGATCCGCATCAACGAGCCACCTTCTTCCGTTGTAATTATCCTGATGGTTTCACATGCAACCAGGCGGAGCTCAGCATGCGTATTGCGAGTGATTTTGGGGCACAGGATTACGGTCGTTATTTCAATGCCTGCACGGACAGCGGCCAGGAACTGGATTTCTTTGACTCGGATACAGATTTAAGCGATAATTCGACCACTGTGCATTCGTGTGCTGTGTGTGGCGTGTCCATGTTGCGCCTTGCCCAGCTCCTGTGgcatcaacaaaaacatcacGGTGAGGTGAAGGACACATTGCCTCATGTCTGCAACAAGTGTAGCTTGGGATTTGTGGCTGAATCGCTGCTTCAACAGCATCGCAGACGCGTCTGTGAAAAGCGCCATGCTAAGCACCAGTGTCAGCATTGCAATCTCCACTTTATCTGGCGGTCTAACTTCGAGCGACACATGGAAGTGCACCATGAGGCGGAAACTGACGGTGTCCTTGAGAACCTGCCCAATACCAGACTAAGAAGTAAACGCAAACAATCTGCCAAACTGCAGTGCAATGAGTGTGAAAAGgtCTTTATCTGGCCCAAGGATCTGACACGCCACAAGCGCATTCATCAGCCGCAGGCTTCGGCCCAGTACGAATGCAGCCACTGTGAGCGCAAGTTTCATCGCAAGGATGGCCTCAAGTCCCACATGCGGGTGCACGCCGAGCAGCACTTGGATGCGACGATTATGCCCACCACCTACCCGGATCCGTCGGTGTTACAGCGGATGCCGATGATGTTGACACAGTTGTGCCAACCGAATGGATGCAAGCGGATTCAATGCATGATCTGCCTATCTCAGCACTCGAAGATCTCTGATCTGCGCACGCATTTGGTGAAGCATCAGTTTAATGTCGAGTTGTCTGAGGAACGTGCCAAGCCAGAGAGCATTGCGAGTATTTGCCGGGATCTATATCCGGAACAGGCGACTCCGCTGGATAAGCAGCAGTTGATTGAGCGCATCCAGATGGATGTGGGCGAGGGAACTGACCTGGAAAGATTCATCTCGATAACCAACGAGGCGGGAATTGAACTTAGTCTGGACAGCAGCGAAACTGAGACGGATTCGGACTCAGCCGAAGTGGAAAAAAGCAGCAGCGGGCGACAATACAGTTGTGATCTGTGTCAGTTGACGTTGCCGCGTAAACATCAAATCTATGCCCACCAGTTGGAGCGGCATACGTGGCAGCAGGCAACCCGCAGTTGTAACCACTGCCAAGCCAGATTTCTCAATGATCAGTTGCTGGATCATCACTATCGAACGCTCTGTCGCAATGTCCACAAGCGATTCTTCTGTAGGAAGTGTCCATTACGATTTCGCTGGCGTGACAACCTGAAGCTGCACACGGACGTGGCGCATCAGGAAGCAAATGGTGAAAAGATGAGCCTAGATGTCCAATTGAATCGGGCAAGTCTCCTCCCGGTTGCCAGCTACGATTGCACCGAGTGTAATCGCAGCTTCAAGATGCAGAAGGATCTGACACGGCACACACTAATGCACGCCCAGGAGTCGACCATTTATCGGTGTCGCTGGTGTGCCCGTCGCTTCTACCGCCAGGCCAATCTCCTGCAGCACATTGAGCGCCATGGTATCAATGCCTCACAGCTGCCCTACGCCGAGTCCCTGCTCAATGCCAGCCGCCATCCTCATGGCCAGAAAAGCATCCAATGCAAGGTGTGCGATATTCGCTTTTCCACAATTGCCGCCCTGCGTTCCCATTTGTCGTCTACGTCGAGCGGGACTCATCATGGTATGGAATCGATGCTCAATTACTCGATTACCGACCAGATGGGCTATGAACTGCACTTGGATGACTCGGAAACGGACGAGGAGGCAAAGCCGCCCGGCATTCCCACCCATTACACCTGCGGCATGTGCCAGCTGCGTTGTGTGCGGAAGTACGAGatgcatcagcatcagcaggcCATGCATCGACTGGAACGGATTGCCGGGAGCTGTGATCAGTGCATTTTTAAGAGCGTTTCCCCCGATATTGTCGCCTACCACCAGCGGGTGCAATGTTGCAACACGGAGAAAAAGTTCAAGTGCGTTACCTGCGGCTACAGGTTTATGTGGGAGTCGAATCTGCTGTTGCACATTCAACTCCAGCATCCCACTAATTGTGATCAGGAGGTGACGCCATCGGTGCCAGCACCGGGGAATTCCACTGCCGAGTGTCAGGTCTTTCAGTGCGGTCAGTGTCCGCGTAAATACAATCGGAAGGACCGACTGACGGCCCATGTGAAGAAGTGTCATGCACCAGGAGCAGTTTCTACAACGAAGACATCGACAGCTTCAGGTGTCGCCAAACAGAAGAGTTTCCTCTGCGCCTTTTGCGGAAAGGCAGTGAGCTCCTCCTCCAATCTCATTATACACATACGTCGCCATACCGGCGAGAAGCCCTTCAAGTGCGACTACTGCGAAATGGCTTTTCCCCGCTCCTCCGACCTACAGTGCCATCGACGCACGCACACTGGCGAACGTCCACATGTTTGCACCGTGTGCCAAAAGGGATTCGCCCGCTCCTACAAGCTACAGCAACATATGCGCATTCATAGTGGCGAGCGTCCCTACAAGTGTACCTATTGCGACAAAAGCTTTACCCAGTCCAATGATCTGACGCTCCACATAAGACGGCACACCGGCGAGCGACCCTATCAATGTAACACCTGTGGGGAACGTTTCATTCAGGGCACAGCGCTCAAGAATCATCGACTTCAGAATGGTCATTACGATGCAGAAGATAGCCCACCTAAAGATAATTAA
Protein Sequence
MLPTNICRTCALHDINLLALSTRTEKYANKSFCDMLHELTQNDPLMEHSDDNLPQYLCGDCLRKLEDAYAFVLQARKVQEELLHKIHKGLQCLDETPIDIATQHIKSESDVALELVKNAADEIEAVSVLALKLQPESETDSSQAEVAEEDVLDFKPTQLRRSSRRAKLTTDSENEATAEDSSAMPLKRRRGRPARVPKGEAINQDGRHACEVCGKTFSWHRDMQRHARVHFEQAGHVYDSCGKGFLRKDKYVFHLRSHEKRQAKQDALQLGNEWRFAERLYSPGRLKRVECKLCGLKCQRIQELREHLTSHVNIDTLSNLSANSDVIVEQFASHQLELMQIKQQVCADIAKGSEHLDKYCVVVNAHGYELCLSDSDEELAGVPPPYQCLLCNTLFSRKYRLISHTLEMHTLPKTKTSWQRCNHCQIGFVCEKLLEQHQRTQCHNQLKRYSCPNCPGKFIWRQNLKQHACSHRMQSSDSQDRERSQGRQIQCCLCDEHLKSMSALRSHLVTHCDGQSGIDPHQRATFFRCNYPDGFTCNQAELSMRIASDFGAQDYGRYFNACTDSGQELDFFDSDTDLSDNSTTVHSCAVCGVSMLRLAQLLWHQQKHHGEVKDTLPHVCNKCSLGFVAESLLQQHRRRVCEKRHAKHQCQHCNLHFIWRSNFERHMEVHHEAETDGVLENLPNTRLRSKRKQSAKLQCNECEKVFIWPKDLTRHKRIHQPQASAQYECSHCERKFHRKDGLKSHMRVHAEQHLDATIMPTTYPDPSVLQRMPMMLTQLCQPNGCKRIQCMICLSQHSKISDLRTHLVKHQFNVELSEERAKPESIASICRDLYPEQATPLDKQQLIERIQMDVGEGTDLERFISITNEAGIELSLDSSETETDSDSAEVEKSSSGRQYSCDLCQLTLPRKHQIYAHQLERHTWQQATRSCNHCQARFLNDQLLDHHYRTLCRNVHKRFFCRKCPLRFRWRDNLKLHTDVAHQEANGEKMSLDVQLNRASLLPVASYDCTECNRSFKMQKDLTRHTLMHAQESTIYRCRWCARRFYRQANLLQHIERHGINASQLPYAESLLNASRHPHGQKSIQCKVCDIRFSTIAALRSHLSSTSSGTHHGMESMLNYSITDQMGYELHLDDSETDEEAKPPGIPTHYTCGMCQLRCVRKYEMHQHQQAMHRLERIAGSCDQCIFKSVSPDIVAYHQRVQCCNTEKKFKCVTCGYRFMWESNLLLHIQLQHPTNCDQEVTPSVPAPGNSTAECQVFQCGQCPRKYNRKDRLTAHVKKCHAPGAVSTTKTSTASGVAKQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCEMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHSGERPYKCTYCDKSFTQSNDLTLHIRRHTGERPYQCNTCGERFIQGTALKNHRLQNGHYDAEDSPPKDN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00558059;
90% Identity
-
80% Identity
-