Basic Information

Insect: Drosophila heteroneura
Gene Symbol: -
Assembly: GCA_035042245.1
Location: JAWNLO010001193.1:47034-60102[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 2.8 1.8e+02 2.8 2.3 3 23 305 327 303 327 0.92

2 14 1 65 4.2 0.7 3 21 468 486 466 490 0.92

3 14 0.23 15 6.2 0.6 2 23 512 534 511 534 0.92

4 14 0.049 3.1 8.3 0.6 1 23 551 574 551 574 0.95

5 14 1.2 74 4.0 0.2 1 21 579 599 579 603 0.90

6 14 0.007 0.45 11.0 0.1 2 23 666 688 665 688 0.95

7 14 0.7 45 4.7 0.2 1 21 693 713 693 713 0.92

8 14 0.0064 0.41 11.1 2.1 2 23 780 800 779 800 0.96

9 14 4.1e-05 0.0026 18.0 1.0 1 23 806 829 806 829 0.97

10 14 0.00029 0.019 15.3 0.4 1 23 855 877 855 877 0.98

11 14 1 66 4.2 0.4 1 23 884 908 884 908 0.95

12 14 0.22 14 6.3 5.6 1 23 913 937 913 937 0.97

13 14 0.0019 0.12 12.7 1.8 1 23 950 972 950 972 0.98

14 14 0.0013 0.08 13.3 3.4 1 20 978 997 978 999 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	2.8	1.8e+02	2.8	2.3	3	23	305	327	303	327	0.92
2	14	1	65	4.2	0.7	3	21	468	486	466	490	0.92
3	14	0.23	15	6.2	0.6	2	23	512	534	511	534	0.92
4	14	0.049	3.1	8.3	0.6	1	23	551	574	551	574	0.95
5	14	1.2	74	4.0	0.2	1	21	579	599	579	603	0.90
6	14	0.007	0.45	11.0	0.1	2	23	666	688	665	688	0.95
7	14	0.7	45	4.7	0.2	1	21	693	713	693	713	0.92
8	14	0.0064	0.41	11.1	2.1	2	23	780	800	779	800	0.96
9	14	4.1e-05	0.0026	18.0	1.0	1	23	806	829	806	829	0.97
10	14	0.00029	0.019	15.3	0.4	1	23	855	877	855	877	0.98
11	14	1	66	4.2	0.4	1	23	884	908	884	908	0.95
12	14	0.22	14	6.3	5.6	1	23	913	937	913	937	0.97
13	14	0.0019	0.12	12.7	1.8	1	23	950	972	950	972	0.98
14	14	0.0013	0.08	13.3	3.4	1	20	978	997	978	999	0.95

Sequence Information

Coding Sequence: ATGAACACCGAGTCGGCAGATCTGGAGGACACGCATCTGTGCATCAAGTGCAATGCGACAATTGTGGGTCTGAGCAAGTATGTTGAGCACCGTAAACGGAATTGCCTCAGCACTGGCGGCGATGAGCACCTGTCGAAGCAGGTGGAGACTCCGGCAACGACGTCGACTGCCAGCGAACAAGTCTCGCACTCAGACATGCGTCGCAGCAACTTGGACCACAGCTATGATGGCTTCCACTTTGCAGAGCCGGAGGCACCCAGCAGTTATCTGCGCAAAACGGCCTCCAGTCATGGCGGAAAGACGTCCAAGTCCCTAACGGATTCCTATGATCCGACGTACGAGCTGGGTGCCGATCTGTTCTTCTcatcgctgcagctgcaaagtGTGTCAACTGGCGGCAAGACAGGTGCACGGCCGGAGCGTGGCGCTAAGGAGGAGCAGAGCTGGCATACGTCCAGCAACTGCTCCGATCCGCTACTAAAAGCGGTCCGGGAACACGAGGAAACCCACTTTAAGTCACTCAAATTTGTGCACTCGCCCGAGGCAAGCGAGGAggaagacgacgacgaggactTCGAGGGCGATGATGAAGAGCATGAGCATGAACATGAACATGAACATGATCACGATCCCGATCCTGAGCCTGATGAGGATTACGATGGGCGTCGCCATTCGCCGCCGACGGTGCCTGCCACGCACACTGGCGGCAAATGGAAGCCAGAGCATCGTCCGCAACTGCAACACACTCACCTGGAACGCATCTCGCCCAGCTGGGATGAGCCGCCCGAGGAACAACACGACCATCCGCCGGCGGAGCACACGCACGGCAAATGGGTGCCGGGCAGCAAGCAGCTGGAGTATCGCGAGAACATCGATCTGACCAAGTTGCAGCAGCCAGGCGCCAGCTACTGGTGCAACATCTGCTGTCGCCGCCTCAAGACGCGCCTCAACTACGAACAGCATCTGCGCAGCGCCTACCATCAGCGGCGCGCCGACGCCGAGCGTCAACTGGAGCAGGCCAATCTCGCAAGCGCCAATCTAACGCTCACCACCAAGGACTTCCCACAGATGCCGCCGACGGAGCAGCTGCcgcgtcgtcgccgtcgtcgtgcCCACTTTCTGCGCTGCGATCTGTGCCGGCACAGCATGGCCCGTCATCTGATGGGCAAGCATCTCATCTCGCACTACCACTATCGccgcctgcagcagcagcaaccgaaCCAGCTGCGCCGACAGAGCGCCCTGCATGACATCCTCGAGCACATGGGCAGCATTGTGAGACAGGCGCCGTTCCAGTGTCTGCCCTGTCGCTTTTATGCCAACACTGAGCAATCCTTTCAGCTGCATTGGCGCTCCTCGACGCACGTGACGCTGACGGAGCGACTTGGTGGCAGCTTCTGGTGCAGCTACTGCCAGTTCGAGTGTGCCAGCAATGAGGAGATGTGGCAACATCTGCTCGGCTCCTCGCACAAGGAGGTGCTCTTTGCGATCAATCGTTCGGTGCCCGTTTGCATTGGCCAGCGTCGTCCGCTGACCTGTTCCCGCTGCAGCGCCAGTTTCCTGTACAATGCGCAGCTGCGGCGTCACTTCGCCTCGGAGCATGTGGGATTGGTGGCAGCGGGCAGCGCTGCCGATGACTATCAGTGTCGCTTTCGCTGTGGGATTTGTGGCGTTGCACAGAGATCTCGAGTGGCGCTGCAGCGGCACGAGAAGCACCAGCATCGATTGGCCAAATACTATTGTGCCCTTTGTCGGCTGGAGTTCGAGACGCCGCTGGAGGCGCGACGCCATCGCAGCCTGATGCAGCACAAGCGGCGAGCTTGCCGAGAATTGAGCCGCAaatccaacagcagcagcagcactaatCAGCCGGATCGCGAGATTCAACACATGCTGCACGAGGtgctggaggagcagcagcctgcagcagcagcagcagcagcagcaggagagcAGCCATCAGCCCTGAGTTCCAAGAGGCGACGCCTGGCCAGCCAGTGTGTCAGCTGTCCGCTCAGCTTTGAGACGCCTCAGGCACTCGTCCAGCATCGTCGCGAGTTGCATCCAGTGGACAATCATGCCTGTCTCAGCTGTGGGAGTAGCTTTCAGTCCGCCCAGGCTCTGGGAAGACACACACGCTGCTGCCAGCCCACAGCGTCCACCTCGACAGCTGTTGCTCccgctgctcctgctccagctccagctccggcTGCAACATCTGAATCAAAGTCATGGAACTGTGCGCAGTGCAGTTTCACTGCTCAATATGAATCGGATTTGCTCTATCATCGCTTCTTTCACACCCACGGCTCGGCAATTGGCAAGAATGAGCTGCTCCAGTGTCCGCTGTGCCCCAAACAGTTTCGCAAGCACTCACTGCGTCCCCATCTGCGCAATCATACGGACGAAAGGATCTTCGAGTGCGTCGAGTGCTCGGCCAAGTTTGCCCGCAGACACAACCTCAAGAATCACATCGCAACAATGCATGGTCCAAAGCAGAAACCATCACCGGCTGCTGATAAGTCAACAGTCGAGCAATCGAAAGTGGTTGCAAAGCAGAAATATCAATGTGGCACCTGTGGCAAAATACTGGCCAAAAAATACTCACTGAAACTACACGAAATGAGCCACGCTGAGGCGGAGCGTCAGCATCGTTGCCACATTGAGGATTGCCAATATGCCGGTCTCACGCCGGAGGCACTCAAAGTCCATCTAATCTCCCATGCGAATGGAAGTCACAAATGTGAACACGACAACTGCCAATATGTGGGCAAAAGTGCGCTGCACTTGAAAAGGCACCTCAAGTCGCATGTGCCCGAAAAGGAGCTGATCGAGGATGGCAAATGGTTTCCGTGCGATCAGTGCGAGTTCAGGGCCCGCATCAGGGGACATCTGAGGCGGCACATGCGTAGCCACACTGGCGAGAAACCCCATCAGTGTCCGCACTGTGACTTCCAGTGCAGCAGCATGGATAATCTGCGCAAGCACATCGTCAAAACGGGCAAGCATCCTGGCAAGTTCATCTACGAGTGTTCCTCCTGCGACACCTTCAAGAGCAACAGTTTCAAGGATCACCGACTACATTTGGCcacgcataaaaataaattgcccTAA
Protein Sequence: MNTESADLEDTHLCIKCNATIVGLSKYVEHRKRNCLSTGGDEHLSKQVETPATTSTASEQVSHSDMRRSNLDHSYDGFHFAEPEAPSSYLRKTASSHGGKTSKSLTDSYDPTYELGADLFFSSLQLQSVSTGGKTGARPERGAKEEQSWHTSSNCSDPLLKAVREHEETHFKSLKFVHSPEASEEEDDDEDFEGDDEEHEHEHEHEHDHDPDPEPDEDYDGRRHSPPTVPATHTGGKWKPEHRPQLQHTHLERISPSWDEPPEEQHDHPPAEHTHGKWVPGSKQLEYRENIDLTKLQQPGASYWCNICCRRLKTRLNYEQHLRSAYHQRRADAERQLEQANLASANLTLTTKDFPQMPPTEQLPRRRRRRAHFLRCDLCRHSMARHLMGKHLISHYHYRRLQQQQPNQLRRQSALHDILEHMGSIVRQAPFQCLPCRFYANTEQSFQLHWRSSTHVTLTERLGGSFWCSYCQFECASNEEMWQHLLGSSHKEVLFAINRSVPVCIGQRRPLTCSRCSASFLYNAQLRRHFASEHVGLVAAGSAADDYQCRFRCGICGVAQRSRVALQRHEKHQHRLAKYYCALCRLEFETPLEARRHRSLMQHKRRACRELSRKSNSSSSTNQPDREIQHMLHEVLEEQQPAAAAAAAAGEQPSALSSKRRRLASQCVSCPLSFETPQALVQHRRELHPVDNHACLSCGSSFQSAQALGRHTRCCQPTASTSTAVAPAAPAPAPAPAATSESKSWNCAQCSFTAQYESDLLYHRFFHTHGSAIGKNELLQCPLCPKQFRKHSLRPHLRNHTDERIFECVECSAKFARRHNLKNHIATMHGPKQKPSPAADKSTVEQSKVVAKQKYQCGTCGKILAKKYSLKLHEMSHAEAERQHRCHIEDCQYAGLTPEALKVHLISHANGSHKCEHDNCQYVGKSALHLKRHLKSHVPEKELIEDGKWFPCDQCEFRARIRGHLRRHMRSHTGEKPHQCPHCDFQCSSMDNLRKHIVKTGKHPGKFIYECSSCDTFKSNSFKDHRLHLATHKNKLP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00528388;
90% Identity: iTF_00482583;
80% Identity: -