Dhet012110.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila heteroneura
Gene Symbol
zfh2
Assembly
GCA_035042245.1
Location
JAWNLO010001165.1:299595-327605[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.00018 0.012 16.0 1.4 2 23 568 590 567 590 0.96
2 11 4.5e-05 0.0029 17.9 0.7 1 23 622 646 622 646 0.92
3 11 0.0079 0.5 10.8 0.4 1 22 745 766 745 769 0.91
4 11 1.8 1.1e+02 3.4 1.9 1 23 965 989 965 989 0.91
5 11 0.27 17 6.0 0.6 1 23 1230 1253 1230 1253 0.97
6 11 8.3 5.3e+02 1.3 0.1 10 23 1368 1382 1359 1382 0.80
7 11 1 64 4.2 2.4 3 21 1449 1467 1447 1471 0.88
8 11 8.6e-05 0.0055 17.0 2.3 1 23 1518 1540 1518 1540 0.98
9 11 0.0013 0.085 13.2 1.2 2 23 1547 1569 1546 1569 0.94
10 11 0.00044 0.028 14.8 1.7 1 23 2273 2295 2273 2295 0.97
11 11 0.0019 0.12 12.7 1.3 1 23 2416 2438 2416 2438 0.98

Sequence Information

Coding Sequence
ATGTCCAGCTCTGATGTTGAAACCTTCAATGGCAAAATAGTTTACAATCTCGACGGCAGCGCGTTTATAATCGATGCAGGCAATGCGACGACTGCACCTCCTGCTCCGCCCGGCAACCATTTAACTACAAGCGGTGCCCgaacaacatcagcatccCCTTGTGATAAATTGAAAGGAGAGACAGCATTTCTCAAATCaggacaaaaaaacaaacagaggAACAAGAAGGATTCGGACGAGGGCTCGGGCGAAGAAGGGGTTGGGTTTGGAGAAGGTGCTTATCAGTTGAGCCCAAAGATCCATTCGTTTCGTGTGGTCTCCGCCCAAGATGCGTGCAATCAAATCCATTTGCATGCAAATACGGATCATCGATTGAATCTGCTGGAGCTGGATAAACAGCTATTGAATCACGAATTATCGAGTGCAATTATTCAGCGGAATATGGATGAGAAACCGCAAATATCGTTTCTGCAGCCACTCGATTGTCTACTCAATGTCAATCTCGAGCAGCAACCAGTCGATTTGGTCAGCAATCAGCAGCAAGTTGCCGCGAGCAATGTAGAAAGTGATAACGATAATAATAACGATGACGTTGGAGATAATGATAACGATGGCATTAGAGATGCCGATaacgataatgataatgataacgataacgatatcACATCTATAAAAGTAGCAGCTGCGCAGGCGTCTGTGAAATTTGGTTCCTTAaattcagcaacagcaacaaagactAATAATTCTACAaaagcaacggcaactgttgcaactgcaactgcaacatcatCGATAACATGCAACTCACCCGCATCAGAATCGCCTCGGCAATCGCCAGCGGAGGCAACATCCGAATGTGGCAGTCAGGAGAGTTCACCTCCAgctgctcctccagctgcttctcctgctcctcatgctgctgctcctcccaCGGCAGATTTAAGAGCTAGTACTGATAATATAAGTAGcgataagttaaataaaagtagCCACAAAGCGGAGGATGCAACAAGCTCAGCCGTGGAGACGCCATCacctcaacagcagcagcagcaacatattgcagatgcagatgcaacagcagcagcaacagctggtgATATATTGCAACACCACCTAATGACCATGCAACATGTGGCTGCCACCGCCACAGCGAGTGGCAGCGTCTACCCACCGTCAACAACAGCACAGGCGCAAATGCAACTTAGTTCCTTTCAAGCATCCCTCGCAGCGCTTGCCAACGAACAGAATGCGAGGGGTGTCAAACTACTAACCGAGTtcctccagcagcagctgcaccaacaacaacagcagcagcatcagaagCATCTTTTGTTCCCCAGCAACTGCCTGGAACATCCCGATTTCAAGGGTATCGATTGCAAGACCTGTGAATTAATTGAGATCCAACATCGCAACAAGTCGCCAGCAACTCCTCAGTCTCAATCTCAGTCTCAACGCTCGCCGAATGCCAGTCTGTCCACGTCCACGTCTATGCCCATCTCGCCCAGCGCCAGCGCCTCATCCAATGTTGCCAATGTGGGCAACCCGTCTGCGTCCAGCTTTACAATTGGCGCCTGCTCCGACCACATTAATGGACGACCTCAAGGCGTCGACTGTGCTCGCTGCGAAATTCTTTTGAGCTCCGCGCGACTCAACAGCGGTGTCCAGATGTCCACCCGCAACTCCTGCAAAACCCTCAAATGTCCCCAGTGCAATTGGCACTACAAATACCAGGAGACACTCGAGATCCATATGCGCGAGAAGCATCCCGATGGAGAGAGCGCCTGTGGATATTGCTTGGCAGGCCAACAACATCCACGTCTGGCACGTGGCGAGTCCTATTCGTGTGGCTACAAGCCGTACCGCTGCGAGATCTGCAACTACTCGACGACGACCAAAGGGAACCTCTCCATTCACATGCAGTCCGACAAGCATCTGAACAACATGCAGGAACTGAACAGTTCCCAAAACATTGTCGCCGTTGCAGCGGCAGCGAAACTGATGTTGCCCAATCCATCACCACAAGGCCCTGTGAGTGGTTGCAGCAATTCCGTCGTCTCGGCAAACCACCAACCCGTTGGCGGCGTCTGTTCCTCGAGTGCCGGTAGTGCCGGCACGGTCAGCAATGCCAGCAACGCATCCAACAGCAGTACAATGGGTTCGGGTACCGGCTCGGGTGCCGGTACGGGTTCGTCAACGGGAGTCTCCTCGCTGAAGCCAAAGCCCTCGTTTCGCTGCGACATCTGCAGCTATGAGACATCCGTGGCACGCAATTTACGCATCCATATGACGAGTGAGAAGCACACGCACAACATGGCCGTCTTGCAGAACAACATCAAGCACATTCAGGCATTCAACtttttgcaacagcagcagcagcaacaaagtgcTGCAGCCGTACCGGGAACGGCTAGCAATAGTTTTTTGCCCGTACCGGAGGTAGCGCTCGCTGATTTGGCCTACAACCAGGCACTGATGATACAGCTCATTCAACACAATGCTGccaatcagcaacaacaacagcagcaacagcagcagcagcagcagcaatctgcTGCCAGCAAGTTATCGCCCACATCGTCCTCACCGGTCAGCACTCCCGACCagttgccacatgccacattcTCGTACTCACCTAAGCTGCTGAAACTGCCGGCTGGCATGATCATGGGCTTAAACATTCCAGAGTCTGGAACAGTCCCCAGCGATTCGCTCGACTCCTATCCGGATAGTTTGCCGGAGCTGTGGCCAACGGCAATGTTCAGTTGCCTCATCTGCGACTGTTTCAGCACCAACAACATGGATGAGCTGAACCAGCATTTGCTCCTGGATCGGTCGCGGCAATCGTCGAGTGCCTCGTCGGATATAATGGTCATACACAACAATAACTATATTTGTCGACTGTGTAATTACAAGACGAATCTGAAGGCGAACTTTCAGCTGCACAGCAAGACGGACAAGCATTTGCAGAAGCTGAATTTCATCAATCACATTCGAGAGGGTGGCGCGCGCAACGAGTTCAAGTTGcaataccagcagcagccgcagcttGCCACAAATGTGGTACAGCTGAAGTGCAACTGTTGCGACTTCCACACCAACTCCATACAAAAACTATCGCTTCACACTCAGCAAATGCGACACGACACAATGCGCATGATCTTCCAGCATTTGCTGCTCATCATCCAAAGGAGTCGTCTGCGCTCTTCGCCGCCGTTGGGCGTCTCGGACTCGGAGCAGTCGACGAAGAAGGCCCTCTGCTGCCAGCTGTGCAATTTTGTGGCCAAGAATCTGCACGAGATGGTGCAGCATGTGAAGGGCTTGCGCCACCTGCAGGTCGAGCAGTTCATCTGCCTGCAACGTAGGAGCGAGAACCTGGACATGCTCGGACTCAACGAGGTCTTCAAGGTGGCAGAAGAACAACCTGGCAGCACGGAAGATGGCAATTTCGATTGCGGCCTAAATCTGGCGACTGCCAGTTGCCTTGTCGGAGCACCCAGCACCGAGACGGGATATggagtggctgctgctgctgctagtagTGCTGTTGGTGGTGGCATCTCCAATGAGGGTCACAACATCTATTCGCCCGCCTCCGTCTCGAGCTGTTCGACAATATGCGGCAAGGTGCGATCGCATGTGGCATCCCCCTTGCCAAGTGTCAGCGAGTTGCAGACGACCGTATTCAAATGCAATCTCTGTGAATACTTTGTGCAATCCAAGAAGGAAATAGAAACGCATATTTTGAGCCTGCATCCAACGGCAGACAGTGATGACTACATAAGCATACCAACTAACACAGCAGCGCTGCAGGCATTCCAAACAGCTGTGGCAGCGGCGGCACTGGCAGCCGTCCAACGTTGCACCACAGCGGGAATAGGAGTTGTACCGGGAACGGGATCAGATGTAGAACTGCCTGGTGGCGATGAAGATAGTGATTGTCCCATTGATATAAAGCGTGAACGGCTCGAGGAGAGTGAATATGCCACAACTGGTGTCCAGGGTACCGTGGAGTCTAATCCCAAAAAGAGTTGCTCGCCCAAAAGTGAATCCATGCCACAGGCGGGTGTCTCCTGTCCGCTCTGCCTGGAGAGCGGTTACAGCGAGCAATCCTCGCTGGAAACCCACCTGATGAGTGTGCACAGCGTGACGAGAGATGGCCTTGCTAGATTACTGCAATTAGTGGATCAAACAGCTTGGCAGGCCGCGAAGAAAACAGATGAGGAACGGAAATTGGAGGAGAGTAAGGCAAGTGGCGAGGAATATCTAACACCATGTGGAGCAGGatcagcaggaggaggagcaacagTTGTCGTCGGTAGTGGCATGCAGGGTGTCTGCTGTCAGCAGTGCGAGGCCAATTTCAAGCACGAggagcaactgctgcagcatgCCCAGCAAACCCAACACTTCCCACAGCAAAATGGCGAATTCGTTTGCCTGCTGAGCCGTGCCTGCTTTGCCAGCTTTGCAACACTACCAGCCATGATAGCCCATTTCAAGGACACACACATGAGCCTGGTCATCTCGGAACGACACGTCTACAAGTATCGCTGTAAGCAGTGCTCGTTGGCATTTAAGACACAGGAGAAACTCACCACACACATGCTGTACCACACGATGCGGGACGCTACAAGGTGCTCACTGTGCCAACGCAACTTTCGCAGTACCCAGGCCCTGCAGAAGCACATGGAACAGGCTCATTCAGCGGAGTGTGccaccactgctgctgttgctagtGCCACAAGTGGCAGTCCCCGCGAAATGTCGCCCAATTACACTAGCACTACCGACATGGAGAAGCCACTACCAACACTACCGGATGAACCAAATGCTTTTGACTTGTCGACGACCAGGACGACTGAATCAGTTGCCAAAACGAATGAGGCTGTGAAGCAATCGTCGCAGCAATCTGGCCAATCGACGCAGCTGCAACTGGAGCCGACCTCCGCTGTGTTGTCGCCCAATGAGGTGGAGGAGCCAACCtcggagcaacaacagcattttgCAGTGCTGACAGCAGCTCTGctcaagcagcaacagcagcagcagaatcatCACCAGGATGCAGTTGGTCAGGCGACGTCttcagcaggagcagcagatGCGCCATCTTTGCCCATTTCCTCCCTGGAGTTGCATCAGTTGCAgAATTTGCAGAACTTGCAACAgatccagcagcagctgagtgCAGCTGCCTCCGCTTCGGGTATGCCCATCAATCCCGTGGATATGCTAAATCTGATGCAATTCCATCATTTGATGTCCTTGAATTTTATGAATCTGGCACCGCCATTGATATTTGGTGGCGCCACTGCTGGTGGCACGAGCGGAGCAGTTGCAGTacaaaacaattgcattgCTCCGAGCAGCTCCAACAGTTGCAACTCCGATCtgcaacaacagaaatgtgCCCCAAATCAGCAGACAACCAATTTAACTAGCGAGGCAAGCAGTTTAAATATGCTAGCACAATCGAATATAGCCAGTAATAATAATCAGCAACAGCTAACCAGCAATCAGAAGAGAGCTCGCACCAGGATCACAGACGATCAGCTGAAGATCCTGCGTGCCCATTTCGACATCAACAATTCACCCAGCGAGGAGAGCATCATGGAAATGTCCCAAAAGGCAAATCTACCAATGAAGGTCGTCAAGCACTGGTTCCGCAACACGTTGTTCAAGGAGCGGCAACGCAACAAAGACTCCCCCTACAATTTCAACAATCCTCCATCAACTACGCTCAATATTGAGGAATATGAACGCACTGGCCAAACAAAGGTGACGCCCCTAAACGAGACTACCCTTACTGCTGCAGCCGCTGGCAGCAACACTGCTGCGACAGCAgtaacaccaacaccaacagcagcaacaacaccaacaattgcagcaacaacatcagttaaaagcaatttaaatttgtcaaCGACAGTTTCAAATATATCCCGCCCAACGTCAGCCAATTCGAGTGCTGGCAACATATCCGATTATTTTAAGACACAAAGCGAACTATTGAATGCCAAACAGGAACAGGAGGAAATactttgtttgccattgccgttgGAGGTGCAAATAAAAACGGAGCcaaatgacaatgacaacaattaCGCATTCCACAAGAAGCAAGATGAGGTCTTCGAGTATttcaagcaacaaaatgatgCAAACGAAACAGCAAGCAGTCAAAATGATCAAaccatgcaacagcagcaacagctgtacacaaaccaacagcagcagcaacaatcgcagcaacagcagcaacaaactcAACAAATCAATAGCTATGAGACGAAATCGGAGAGTGGCAGTTCCGATGTCCTTTCTCGTCCTCCGACGCCAAATAGTGTTGCTGCGAGCAATATTTACAGCAGCATGAATGATTTGCTAAGTCAACAGCTGGAGAATATGGGCAGTAATATGGGTCCACCGAAGAAGCTGCAAATATCGGGAAAATCCTTTGAGAAAATCGCTTCGACTTCAGCTTTAatatcctcctcctcatcggcTTGCAATCAGCTCGAAAGTAACTCTTCGAATTCCTCAAATTCATCATCTTCCACATCGGGTGGCAAACGTGCGAATCGCACTCGTTTCACCGACTATCAAATCAAGGTCCTGCAGGAGTTCTTCGAGAACAATTCGTATCCCAAGGACAGTGATTTGGAATATCTCAGCAAACTACTATTGCTCTCGCCTCGAGtaattgttgtttggtttCAGAATGCGCGACAAAAACAGCGCAAAATCTACGAAAACCAACCAAATAATTCGCTCTACGAAAGTGAGGagaccaaaaaacaaaatattaattatgccTGCAAGAAATGCAGCCTGGTCTTCCAACGCTACTACGAACTGATAAGGCATCAGAAGAATCACTGTTTCAAGGAAgagaacaataaaaaatcgGCCAAAGCACAAATTGCCGCCGCACAAATTGCCCATAATCTCAGCTCGGAGGATTCCAATTCCTCGATGGATATTCATCATGGAGTTGCTGGTACCAGTTCAGTTGGACTGTCGCCAAATGTggctgctgtagctgctgtggctgtggcagctgctgcagctgcacacTCAACCGGGACACAGGCCTTTGGCTCCTCGCCATCGCCACAGCATTTGTTTAGTAAGTCTTCGTCGCTGACCGATTTTAGTCcatcaacaacaccaacaccgcCGCAAAGGGAGAGGAGCAATTCCCTcgatcatcaacagcagcagcaacgcctgCCCAAATTCGAGTGTGACAAATGTGAATTGCAGTTCAATCATTTGGAACTGCTGAGAGAGCATCAATTAATGCATCTGATGAGTCCTGCACTCTTTAATCAATCAAACCCGGGGGAAACCAGCTACGGGCCCTTTGGCAGCATTTTGCAAGGACTGCAACaggcagcacagcagcaacagcagcaccagcagcaccaacagcaccaacagcatcaATCACAGCCACCGCCAGCCAAAAAGCGCAAATATTCCGAGAGCTCAAATCCGGAGGAGGCAACATTGAACGATTTTGAAACTGCGCACAAAAAATACGAGTTCCTTTTCCAATATTTTCTGCAACACGAAACCAATGCGGAAGTCAAGCAACAATTCCtcatgcagcaacagcagcaacagcatcaatcACAGCCAACCGAGTCCGACTTGGAGTTGGAATTTTTGAGTAATTTCTATCAGCAAAGCGAGTTAAAAAAGGGTGGCAGTTATGATTTTCTACTACAATACTATCGAAAGCATGAAGATCCCCAGAAATCACAGCAATCATCGTTTAGTTCCAGTAAAAAACCCACGATTGAATTTCTATTGCAATACTATCAGCTGAATGAGTCGAAAACGTTTTTTCAGTTAGCTGCCTCGCCCCAAATAACACCCGATGATGGTCGCCTCGAATTGCAGCCGTCGTCGAAGGGGCCGAACACGACGACGGATGAAACCATTAAAACTATCGGCACTCACGATGAACCACTGGGCATTACTCACGACCGGAATATTGATCTACAAtattatacaacaaaaacgGGAATTAAGGAAGAAATCGAGCAGGTAATCAGCAGCTCGAAAAATGGCTTAAATAATGATTTAGCTGATCTACACgagaaattgaataataatcatattaatattaatgttggTCAACATTTCGATTTGAGGGAGTCGAAGGAGAATGAAACCGTTTTGCCCAGTTCAACTGGCTTAAAtgatcaatcaatcaatccaTCAATCATCAATGGGGACAACACTCAAACATCTTTGCTGGTCATGCGCAAATCGAGCAACGATAACGACAAATCGCAGTATTTTCAAAATCTAGAGGATTTTCTCGATGCCACCATGATTGAGAATAACTCACAAATGCTGACATTCAACGATGACGATAATAATCCCAGTCCCAATGTGGAGAGTGTGAATTTATCGGCGGTCAATGCCAATGATGGTATTCCCTCCGATTCATCAATTCAGCTGAGTGCCCCAtccaagcaaaacaaacgatTGCGCACCACAATATTGCCGGATCAATTGAATTTCCTATATGAGTGCTACCAGACCGAGTCAAATCCGAGCCGCAAAATGCTCGAAGAGATCTCCAAGAAAGTTAATCTTAAAAAGCGAGTAGTCCAGGTTTGGTTTCAAAACTCCCGGGCCAAAGACAAAAAGTCACGAAATCAGCGCCAATATGCGCACATTTCggacgacaacaacagttttGATGGATCGATTGGCAAGGAAGctggcaacaccaacaacagctacagtaacaacaacagcaacaacaacagcctaAAAAGAACGAGCAAAGAGCCAATGGCCAATGTTATTAACAGCGAACATGTGACCATGCACAAACATGCATTCACCGTGGAACACATCTGTAAAATGAAAGAGCTGCTCGAACAGAAGACATGTGAACTGTACGCAAACAGCAATGCGAGCGGCAGCGATGACAACGACTCGGAACGAGAAAGACGTGTTTACAGCCTGTCTAAGGCATTTCTGCTGCAGCATGTTGTTGCCAataacagcggcagcaataaGAGTCTGTCCGCAGCAGCATTGCCAGCCGAATTAAATTTCGATGCGAATGCAGCATCGGCGACTGTtacgacgacgccgacgacgacggcgacaacagcagccgatGATTCGAACGTTGGTCCAAACACGAAGCGACGGCATCGTGCCAGCGATTTGCCCGATGATGATATTGCCGATGAGGCAATTGAGACGCCGAGCCGAAAGCAAGCGTCGACCAACCGTGAACTAATGCAGCAGATGTTCAATCGCAATCACATCACTGTTATAGgtggcaaataa
Protein Sequence
MSSSDVETFNGKIVYNLDGSAFIIDAGNATTAPPAPPGNHLTTSGARTTSASPCDKLKGETAFLKSGQKNKQRNKKDSDEGSGEEGVGFGEGAYQLSPKIHSFRVVSAQDACNQIHLHANTDHRLNLLELDKQLLNHELSSAIIQRNMDEKPQISFLQPLDCLLNVNLEQQPVDLVSNQQQVAASNVESDNDNNNDDVGDNDNDGIRDADNDNDNDNDNDITSIKVAAAQASVKFGSLNSATATKTNNSTKATATVATATATSSITCNSPASESPRQSPAEATSECGSQESSPPAAPPAASPAPHAAAPPTADLRASTDNISSDKLNKSSHKAEDATSSAVETPSPQQQQQQHIADADATAAATAGDILQHHLMTMQHVAATATASGSVYPPSTTAQAQMQLSSFQASLAALANEQNARGVKLLTEFLQQQLHQQQQQQHQKHLLFPSNCLEHPDFKGIDCKTCELIEIQHRNKSPATPQSQSQSQRSPNASLSTSTSMPISPSASASSNVANVGNPSASSFTIGACSDHINGRPQGVDCARCEILLSSARLNSGVQMSTRNSCKTLKCPQCNWHYKYQETLEIHMREKHPDGESACGYCLAGQQHPRLARGESYSCGYKPYRCEICNYSTTTKGNLSIHMQSDKHLNNMQELNSSQNIVAVAAAAKLMLPNPSPQGPVSGCSNSVVSANHQPVGGVCSSSAGSAGTVSNASNASNSSTMGSGTGSGAGTGSSTGVSSLKPKPSFRCDICSYETSVARNLRIHMTSEKHTHNMAVLQNNIKHIQAFNFLQQQQQQQSAAAVPGTASNSFLPVPEVALADLAYNQALMIQLIQHNAANQQQQQQQQQQQQQQSAASKLSPTSSSPVSTPDQLPHATFSYSPKLLKLPAGMIMGLNIPESGTVPSDSLDSYPDSLPELWPTAMFSCLICDCFSTNNMDELNQHLLLDRSRQSSSASSDIMVIHNNNYICRLCNYKTNLKANFQLHSKTDKHLQKLNFINHIREGGARNEFKLQYQQQPQLATNVVQLKCNCCDFHTNSIQKLSLHTQQMRHDTMRMIFQHLLLIIQRSRLRSSPPLGVSDSEQSTKKALCCQLCNFVAKNLHEMVQHVKGLRHLQVEQFICLQRRSENLDMLGLNEVFKVAEEQPGSTEDGNFDCGLNLATASCLVGAPSTETGYGVAAAAASSAVGGGISNEGHNIYSPASVSSCSTICGKVRSHVASPLPSVSELQTTVFKCNLCEYFVQSKKEIETHILSLHPTADSDDYISIPTNTAALQAFQTAVAAAALAAVQRCTTAGIGVVPGTGSDVELPGGDEDSDCPIDIKRERLEESEYATTGVQGTVESNPKKSCSPKSESMPQAGVSCPLCLESGYSEQSSLETHLMSVHSVTRDGLARLLQLVDQTAWQAAKKTDEERKLEESKASGEEYLTPCGAGSAGGGATVVVGSGMQGVCCQQCEANFKHEEQLLQHAQQTQHFPQQNGEFVCLLSRACFASFATLPAMIAHFKDTHMSLVISERHVYKYRCKQCSLAFKTQEKLTTHMLYHTMRDATRCSLCQRNFRSTQALQKHMEQAHSAECATTAAVASATSGSPREMSPNYTSTTDMEKPLPTLPDEPNAFDLSTTRTTESVAKTNEAVKQSSQQSGQSTQLQLEPTSAVLSPNEVEEPTSEQQQHFAVLTAALLKQQQQQQNHHQDAVGQATSSAGAADAPSLPISSLELHQLQNLQNLQQIQQQLSAAASASGMPINPVDMLNLMQFHHLMSLNFMNLAPPLIFGGATAGGTSGAVAVQNNCIAPSSSNSCNSDLQQQKCAPNQQTTNLTSEASSLNMLAQSNIASNNNQQQLTSNQKRARTRITDDQLKILRAHFDINNSPSEESIMEMSQKANLPMKVVKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNIEEYERTGQTKVTPLNETTLTAAAAGSNTAATAVTPTPTAATTPTIAATTSVKSNLNLSTTVSNISRPTSANSSAGNISDYFKTQSELLNAKQEQEEILCLPLPLEVQIKTEPNDNDNNYAFHKKQDEVFEYFKQQNDANETASSQNDQTMQQQQQLYTNQQQQQQSQQQQQQTQQINSYETKSESGSSDVLSRPPTPNSVAASNIYSSMNDLLSQQLENMGSNMGPPKKLQISGKSFEKIASTSALISSSSSACNQLESNSSNSSNSSSSTSGGKRANRTRFTDYQIKVLQEFFENNSYPKDSDLEYLSKLLLLSPRVIVVWFQNARQKQRKIYENQPNNSLYESEETKKQNINYACKKCSLVFQRYYELIRHQKNHCFKEENNKKSAKAQIAAAQIAHNLSSEDSNSSMDIHHGVAGTSSVGLSPNVAAVAAVAVAAAAAAHSTGTQAFGSSPSPQHLFSKSSSLTDFSPSTTPTPPQRERSNSLDHQQQQQRLPKFECDKCELQFNHLELLREHQLMHLMSPALFNQSNPGETSYGPFGSILQGLQQAAQQQQQHQQHQQHQQHQSQPPPAKKRKYSESSNPEEATLNDFETAHKKYEFLFQYFLQHETNAEVKQQFLMQQQQQQHQSQPTESDLELEFLSNFYQQSELKKGGSYDFLLQYYRKHEDPQKSQQSSFSSSKKPTIEFLLQYYQLNESKTFFQLAASPQITPDDGRLELQPSSKGPNTTTDETIKTIGTHDEPLGITHDRNIDLQYYTTKTGIKEEIEQVISSSKNGLNNDLADLHEKLNNNHININVGQHFDLRESKENETVLPSSTGLNDQSINPSIINGDNTQTSLLVMRKSSNDNDKSQYFQNLEDFLDATMIENNSQMLTFNDDDNNPSPNVESVNLSAVNANDGIPSDSSIQLSAPSKQNKRLRTTILPDQLNFLYECYQTESNPSRKMLEEISKKVNLKKRVVQVWFQNSRAKDKKSRNQRQYAHISDDNNSFDGSIGKEAGNTNNSYSNNNSNNNSLKRTSKEPMANVINSEHVTMHKHAFTVEHICKMKELLEQKTCELYANSNASGSDDNDSERERRVYSLSKAFLLQHVVANNSGSNKSLSAAALPAELNFDANAASATVTTTPTTTATTAADDSNVGPNTKRRHRASDLPDDDIADEAIETPSRKQASTNRELMQQMFNRNHITVIGGK