Basic Information

Insect: Drosophila heteroneura
Gene Symbol: -
Assembly: GCA_035042245.1
Location: JAWNLO010000390.1:556794-561307[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 25 0.00051 0.032 14.6 0.9 1 23 213 235 213 235 0.97

2 25 0.0006 0.038 14.3 2.8 2 23 242 263 241 263 0.97

3 25 0.019 1.2 9.6 0.7 2 23 296 317 295 317 0.96

4 25 0.00024 0.015 15.6 2.0 1 23 392 415 392 415 0.94

5 25 0.19 12 6.5 0.8 2 22 425 445 424 445 0.96

6 25 4.1 2.6e+02 2.3 0.4 1 19 454 472 454 474 0.91

7 25 0.0044 0.28 11.6 0.5 1 23 592 615 592 615 0.96

8 25 0.012 0.78 10.2 0.1 1 21 624 644 624 645 0.95

9 25 0.0031 0.19 12.1 4.3 1 23 654 677 654 677 0.97

10 25 6.3e-05 0.004 17.4 0.4 2 23 688 709 687 709 0.97

11 25 1.4e-05 0.00088 19.5 5.2 1 23 715 737 715 737 0.98

12 25 0.11 7.2 7.2 1.0 1 23 876 899 876 899 0.95

13 25 0.0068 0.43 11.0 1.9 1 22 906 927 906 927 0.96

14 25 0.096 6.1 7.4 0.3 1 20 936 955 936 959 0.88

15 25 5.7e-05 0.0036 17.6 1.6 1 23 983 1005 983 1005 0.97

16 25 0.00043 0.027 14.8 0.7 1 23 1012 1034 1012 1034 0.98

17 25 0.13 8.1 7.0 0.0 2 21 1061 1080 1060 1081 0.94

18 25 0.038 2.4 8.7 4.0 1 23 1126 1149 1126 1149 0.96

19 25 0.0086 0.55 10.7 1.2 1 23 1186 1209 1186 1209 0.96

20 25 0.014 0.87 10.1 3.1 1 23 1236 1259 1236 1259 0.97

21 25 1.3e-05 0.00083 19.6 0.1 2 23 1280 1301 1279 1301 0.95

22 25 4.5e-05 0.0028 17.9 2.9 1 23 1307 1329 1307 1329 0.99

23 25 4.1e-06 0.00026 21.2 2.3 1 23 1335 1357 1335 1357 0.97

24 25 2.8e-07 1.8e-05 24.8 2.6 1 23 1363 1385 1363 1385 0.99

25 25 0.00066 0.042 14.2 0.3 1 21 1391 1411 1391 1415 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	25	0.00051	0.032	14.6	0.9	1	23	213	235	213	235	0.97
2	25	0.0006	0.038	14.3	2.8	2	23	242	263	241	263	0.97
3	25	0.019	1.2	9.6	0.7	2	23	296	317	295	317	0.96
4	25	0.00024	0.015	15.6	2.0	1	23	392	415	392	415	0.94
5	25	0.19	12	6.5	0.8	2	22	425	445	424	445	0.96
6	25	4.1	2.6e+02	2.3	0.4	1	19	454	472	454	474	0.91
7	25	0.0044	0.28	11.6	0.5	1	23	592	615	592	615	0.96
8	25	0.012	0.78	10.2	0.1	1	21	624	644	624	645	0.95
9	25	0.0031	0.19	12.1	4.3	1	23	654	677	654	677	0.97
10	25	6.3e-05	0.004	17.4	0.4	2	23	688	709	687	709	0.97
11	25	1.4e-05	0.00088	19.5	5.2	1	23	715	737	715	737	0.98
12	25	0.11	7.2	7.2	1.0	1	23	876	899	876	899	0.95
13	25	0.0068	0.43	11.0	1.9	1	22	906	927	906	927	0.96
14	25	0.096	6.1	7.4	0.3	1	20	936	955	936	959	0.88
15	25	5.7e-05	0.0036	17.6	1.6	1	23	983	1005	983	1005	0.97
16	25	0.00043	0.027	14.8	0.7	1	23	1012	1034	1012	1034	0.98
17	25	0.13	8.1	7.0	0.0	2	21	1061	1080	1060	1081	0.94
18	25	0.038	2.4	8.7	4.0	1	23	1126	1149	1126	1149	0.96
19	25	0.0086	0.55	10.7	1.2	1	23	1186	1209	1186	1209	0.96
20	25	0.014	0.87	10.1	3.1	1	23	1236	1259	1236	1259	0.97
21	25	1.3e-05	0.00083	19.6	0.1	2	23	1280	1301	1279	1301	0.95
22	25	4.5e-05	0.0028	17.9	2.9	1	23	1307	1329	1307	1329	0.99
23	25	4.1e-06	0.00026	21.2	2.3	1	23	1335	1357	1335	1357	0.97
24	25	2.8e-07	1.8e-05	24.8	2.6	1	23	1363	1385	1363	1385	0.99
25	25	0.00066	0.042	14.2	0.3	1	21	1391	1411	1391	1415	0.91

Sequence Information

Coding Sequence: ATGTTGCCGACGAATATTTGTCGCACGTGTGCATTGCAAGATGACAATTTGTTGGCGTTGGCAACGCGGAGTGAGAAATACACAAAGAAAAGTATTTGCGACATGCTGCACGAATTAACACAAATCGATCCACTGCTGGAGCATACAGATGATAAGCTACCACAGCATTTATGCGGCCAATGCTTGAGCCAGCTAGAAGCTGCCTATGCATTTGTGCTGCAGGCACGCCAAACGCaggagcaactgttgctgcagctacGTAAGGGATTGCAAACACTGTGCCTGGACGAAACACCCATCGATATAAGCATAGAGCACATCAAAATCGAAACAGACATTGACCTAGATGCAGACATTGCTGACTTAGTCGATGCTGAgttggaggaggagcaggagaagCAGGTGGCCTTAAAATGTCATCCGGCAACTGATAGCGATAGCAGTCAAGATAATGTGAAGGACCATCACATTAGGGTTAAAACCCCGCAGCTGCGGCGCAGTGCACGGCGAGCCAAACTCAGCACAGACAGCGAGAATGAGTCGTGCGAGCAGGTGAAGCCGTTGCCTGTTAAGCGTGGACGCGGTCGTCCCGCACGTCTGGCCAAGAGGGAGACGACCACCAACGAGGACGGGCGGCATGTGTGCGAGGTGTGCGGCAAGACCTTCTCCTGGTATCGCGACATGCAGCGCCATGCGCGCATCCACTTTGAGCAGGCGGGTATTGTGTGCGAGCACTGCGGCAAGAAGTTCCTGCGCAAGGACAAATACATGACACATCTGCGATCGCACAAGAAGCACGCAaccacagacagacagacactgCCACGGAGCAGCGAGTGGCGCTACGCGGAGCGTCTCTATAGCCCCGGCAGATTCATGCGTGTGGAGTGCAAACTGTGCGGCTTGAGTTGCCAGCGCATTCGGGAGTTGCGCGAGCACTTGGCGAGTCATGTTCACATTGAGACATTGTCGAATCTCAGCCTGGATAACGATGTCATCCGTGAGCAGTTTGGCAGCCAATTGGATTTGCAGCAAATCAAGGAAAAGGTGTGCACGCAAATTGCCAAAGGTCGCGAGCAACTGGAGAATTACGGCGCCGTGGTGAATGCTTACGGTTATGAGCTTTGCCTCAGCGACTCGGATGATGAGGAGGATGGGGAGTTGGCTAGCAATTATCAATGTCTGCGCTGCAATGTCAGCTTTGCACGCAAGCATCAACTCATGCGTCACACGCTCGAGGAGCACACGGACAGAAGTGAGACTCTTTTGAAACGCTGCAATATCTGTCAAATTGGCTTTGTTTGCGCCAAGCTGCTGGAACAGCATCAGCGCACGCAGTGCCTAAATCCACTGAAGCGTTACAGCTGCGAGAATTGTCCTGGCAAGTTTATTTGGCTGCAGAATCTGCAGCAACATGCATGCTGCAGACTGCAACCGGATATGCAGCATCGGCAtccggagcagcagcaggcacctCATCACCAGATACAATGTTGCCTGTGCGAAGTCCAACCCAGCAGCATGACTGCCCTACGTTCTCATTTACTCACGCATCGTGATGGACATACCGACATTGATCCGCAGCAGCAATCTGCCTTCTTTCGCACCTATTACGAGGATGACGGCGCCAGCAGCCTGTCGGAGCTCAGGGCACGCATCGCTGGCGATTTTGAGGCACAGCTTTATGGAAGATATTTCAATGCGTGCACGGACAGTGGACAAGAACTCGACTTCAACGACTCCGACAAGGAATGGAGGGATGCGCCCGCTCTGCACAGCTGTGCCGTGTGTGGCGAGAGCAGAATCCGCCTCGATCAGCTACTCCAGCATCAGCAGAGCCAGCACATAGAGCTAGCGGGCAGCCTGCCTCATGTCTGCTCCGATTGTGGATTGGGATATGTGGCCgagtcgctgctgcagcagcatcgtcGTAACATCTGTGGCAAGGTGCATGCCAAGTATCAGTGTCCACATTGCAGTCAGCGCTTCTATTGGCACTCCAACTACGAGCGGCACATTCAGGTGCAACATAcgaagcaggagcaggagaagAGCAATCTTCAGTGCAGCGAGTGCGATAAGGTGTTCATCTGGCCCAAGGATTTGACCCGCCACAAGCGCATGCATCAGTCGCAGGTGCAGTTCGAATGTGCGCACTGCGATCGCAAGTTTCATCGCAAGGATGGTCTTAAGTCGCACATGCGGATGCACGGCGAGCAGCCGACGTCGTCTCTCGGTGAGCAGCTGCAATGCATGCCGATGGTTTTGAGCCAGCTATGTCGCCCTAATGGCTGCAAGCAGATCAAGTGCATGATTTGCCTGTCGCAGCACACAAAGATCTCCGATTTGCGAACGCATTTGACTAGCCATCAGTCGACGCTGTGTTTGGCCGAGGATCGAGGCATCACAAACATTTGTCATGCTCTTTATCCGGAGCTGAACACTCCACTGGATCAGCAGGCATTGATCGAGCGCATCCAGCGTGATCTAACCAATGGCTTGGAGCTGGAAAGATTCGTTTCGATAACCAACGAGGCGGGCATCGAACTAAGCCTGGACAGCAGTGAAACGGACACGGATTCGGATTGTGCAGCAGAAACCGAACGGAGCAGCACGGAACGCCGTTACAGCTGTGAACTGTGCCAGGTGCAGGTGATGCGCAAGCATCAGCTCTATGCCCACCAGCTGGAACAGCACACTTGGCACCAGACGACGCACGTGTGCAGCCACTGCCAGGCGAGATTCGTGaatgagcagctgctggcgcaTCACTATCGCACCCTCTGCCGCAATGCACAAAGGCGTTTCCCGTGTCGCAAGTGTCCGTTGCGCTTTCGCTGGCGCGACAATTTGAAGCTGCACAATGGTGTGGCGCATCAGGAGCGAGGGACCGTGGAACAGCACGCCAATGTGGACATTCAGTTGCGTATGCTGCCGGTGGTTAGCTATGACTGTGTCGAGTGCAAGCGTagctttaaaatgcaaaaggaTCTCACACGGCACACCCTGATGCATGCCCAGGAGTCGAGCATCTATCGGTGTCGCTGGTGCGCACGACGCTTCTATCGCGAGGCGAATCTGCTGCAGCACATCGAGCGACATGGCATCAGCGCCGACCAGCTGCCCTATGCGGAGGCCCTGCTCAACGCCAGCCGGCATCCGCATGGCCCGAAGTGCATTCAGTGTCGCGTGTGTGAATTATCCTTTGGCAGCATTGCGGCACTGCGTTCGCATCTGCAATCGTCGCCAATTGGCACTCATCATCCGATTGAGTCTATGGCCAACTATTCAATCACCAATCAGCTGGGCTACGAGCTGCACCTGGACGACTCCGAAACGGATGAGGAAGCCAAGCCGGCCGGCACTCCAGCGCATTACACGTGCGGCATGTGCCAGCTGCGCTGTGTGCGCAAGTTTGaactgcatcagcatcagcaggccATGCATCGTCTGGAGCGCATCGCCGACGGCTGCAATCTGTGCATCTTCAAGAGCGTCTCGCCCGATCTGATTGCCTATCATCGGCGTGTGCTGTGCGAGAACACGGAGAAGCAGTTTAAGTGCTCTAACTGTAGCTACAAGTTTATGTGGCAGTCGAATCTGGTGCAGCACATCCAACTGCAGCATCCCAGCAGCGAGGAGtcgccaacaaaaacaacaatgcccAAGACCGTGCCCGACATTGACAACGACGAATGCCACATCTTCCAGTGTGGTCAGTGTCCCAGTAAATACAATCGCAAGGATCGCCTCACCGCCCATGTGAAAAAGTGTCACACAACTGGCGCAACTGTGTCAACAAAACCGCCAGTGGCTACCAAGCAGCAGAAGAGTTTCCTGTGCGCCTTTTGCGGCAAGGCGGTGAGCTCATCCTCCAATTTAATCATACACATTCGTCGGCACACCGGCGAGAAGCCGTTCAAGTGTGATTACTGCGACATGGCCTTTCCGCGCTCCTCCGATCTCCAGTGCCATCGACGCACCCACACCGGCGAACGGCCCCACATCTGCACCGTCTGTAAGAAGGGATTCGCTCGCTCGTataagctgcagcagcacatgCGCATCCACAACGGCGAACGGCCCTACAAGTGCACCTTCTGCGACAAGAGCTTCACCCAGTCCAATGACCTCACCCTCCACATCCGCCGCCACACGGGCGAACGCCCTTATCAGTGCAATACTTGCGGCGAGCGATTCATTCAGGGCACAGCGCTAAAGAACCATCGACTGCAGAATGGCCACAACGAGACGGAAGTGGATCAATCGAAGGATGACTAA
Protein Sequence: MLPTNICRTCALQDDNLLALATRSEKYTKKSICDMLHELTQIDPLLEHTDDKLPQHLCGQCLSQLEAAYAFVLQARQTQEQLLLQLRKGLQTLCLDETPIDISIEHIKIETDIDLDADIADLVDAELEEEQEKQVALKCHPATDSDSSQDNVKDHHIRVKTPQLRRSARRAKLSTDSENESCEQVKPLPVKRGRGRPARLAKRETTTNEDGRHVCEVCGKTFSWYRDMQRHARIHFEQAGIVCEHCGKKFLRKDKYMTHLRSHKKHATTDRQTLPRSSEWRYAERLYSPGRFMRVECKLCGLSCQRIRELREHLASHVHIETLSNLSLDNDVIREQFGSQLDLQQIKEKVCTQIAKGREQLENYGAVVNAYGYELCLSDSDDEEDGELASNYQCLRCNVSFARKHQLMRHTLEEHTDRSETLLKRCNICQIGFVCAKLLEQHQRTQCLNPLKRYSCENCPGKFIWLQNLQQHACCRLQPDMQHRHPEQQQAPHHQIQCCLCEVQPSSMTALRSHLLTHRDGHTDIDPQQQSAFFRTYYEDDGASSLSELRARIAGDFEAQLYGRYFNACTDSGQELDFNDSDKEWRDAPALHSCAVCGESRIRLDQLLQHQQSQHIELAGSLPHVCSDCGLGYVAESLLQQHRRNICGKVHAKYQCPHCSQRFYWHSNYERHIQVQHTKQEQEKSNLQCSECDKVFIWPKDLTRHKRMHQSQVQFECAHCDRKFHRKDGLKSHMRMHGEQPTSSLGEQLQCMPMVLSQLCRPNGCKQIKCMICLSQHTKISDLRTHLTSHQSTLCLAEDRGITNICHALYPELNTPLDQQALIERIQRDLTNGLELERFVSITNEAGIELSLDSSETDTDSDCAAETERSSTERRYSCELCQVQVMRKHQLYAHQLEQHTWHQTTHVCSHCQARFVNEQLLAHHYRTLCRNAQRRFPCRKCPLRFRWRDNLKLHNGVAHQERGTVEQHANVDIQLRMLPVVSYDCVECKRSFKMQKDLTRHTLMHAQESSIYRCRWCARRFYREANLLQHIERHGISADQLPYAEALLNASRHPHGPKCIQCRVCELSFGSIAALRSHLQSSPIGTHHPIESMANYSITNQLGYELHLDDSETDEEAKPAGTPAHYTCGMCQLRCVRKFELHQHQQAMHRLERIADGCNLCIFKSVSPDLIAYHRRVLCENTEKQFKCSNCSYKFMWQSNLVQHIQLQHPSSEESPTKTTMPKTVPDIDNDECHIFQCGQCPSKYNRKDRLTAHVKKCHTTGATVSTKPPVATKQQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCDMAFPRSSDLQCHRRTHTGERPHICTVCKKGFARSYKLQQHMRIHNGERPYKCTFCDKSFTQSNDLTLHIRRHTGERPYQCNTCGERFIQGTALKNHRLQNGHNETEVDQSKDD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00577186;
90% Identity: iTF_00610043;
80% Identity: -