Basic Information

Insect: Drosophila helvetica
Gene Symbol: -
Assembly: GCA_963969585.1
Location: OZ018403.1:9289992-9296457[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.055 5.2 8.2 0.6 1 23 1226 1249 1226 1249 0.94

2 8 0.01 0.99 10.4 0.1 1 23 1254 1277 1254 1277 0.98

3 8 0.0085 0.81 10.7 2.6 1 23 1473 1496 1473 1496 0.95

4 8 0.00047 0.045 14.7 2.1 1 23 1504 1526 1504 1526 0.98

5 8 5.3e-05 0.005 17.6 0.8 1 23 1533 1556 1533 1556 0.97

6 8 5.7e-05 0.0054 17.5 1.4 1 23 1562 1584 1562 1584 0.96

7 8 1.4e-06 0.00013 22.6 0.6 1 23 1589 1611 1589 1611 0.99

8 8 0.0093 0.88 10.6 3.1 1 23 1617 1639 1617 1639 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.055	5.2	8.2	0.6	1	23	1226	1249	1226	1249	0.94
2	8	0.01	0.99	10.4	0.1	1	23	1254	1277	1254	1277	0.98
3	8	0.0085	0.81	10.7	2.6	1	23	1473	1496	1473	1496	0.95
4	8	0.00047	0.045	14.7	2.1	1	23	1504	1526	1504	1526	0.98
5	8	5.3e-05	0.005	17.6	0.8	1	23	1533	1556	1533	1556	0.97
6	8	5.7e-05	0.0054	17.5	1.4	1	23	1562	1584	1562	1584	0.96
7	8	1.4e-06	0.00013	22.6	0.6	1	23	1589	1611	1589	1611	0.99
8	8	0.0093	0.88	10.6	3.1	1	23	1617	1639	1617	1639	0.99

Sequence Information

Coding Sequence: ATGATGTCTAATAAACGATTCCCTCATTTGTTTCGCACACAGGTCAGCCGCGACGATGGTCTGCCGCAGGAGATTTGCCGCCAGTGCATGGCCCAGTTCCTGATGGTGGCCAAATTCCGAAGGAAATGCGTGCGGATGCAGCAGCGTCTGCAGGACTATGCCCAGGAAATATCCGACCGGCAGGCGGCCAGAGAGGCCAAGcgaaagcagaagcagcaacagaggCTGGAGCTGCAGCAAGAAGGGCAGACAAAGCAAAAGGACCTGAAGGACATGGACACGGATGCCAATTCATCGGACTACATGCATTTGCCGGAAACACAGATGGAACGAAAGCGTCGCATAATCTCCGAATCGGAGGGCGAGTCCCCATCGACCCCGCGACCATCAAGGCCGAAAATTGTGAAAACAGAGGAGGTCCTGCCACCGCCCAAGGAGCGTCGCCTGCAGCTGAGATTGCGCAGAATGCGAACACAGTCCGCAGGAGCATCGGCAGGGGATGCCAATGCTGATGAGGATGCGAATGCCGATCCGATTGTGAATGCGGAGGCGGAAGAACCACCACGGACGCTCGCTGATCCCAGCAGCATGCCCTGGAAGACAAAGGCGGCGAGGAAGCAGCTGTCCGAGTCGTGGTCCAGCTGCTCGCCGGCCCTCTCCTCGGAGATGGGGGGCCGCAGGAGCACCAGCAGCGAGACGGCCACGGAACATCTGAGCGATCTGTCCGTGGGGCCACTCTGTGGCTTCGAGAGCGACAGCAATCCCTCCTCCAGCTCAGCGCCAACGACCCTCAAATTCCCCAGACGATCGCCCACAGCAGTCCCGGCACTGCGACGTGGCCGTCGACCCCGGAGCTCGCCCGTTTACATGGCCGTCAAGCGGCAACGGCGATCCCTGAGCAAGAAGCCGACGGCGAAGGAGCTCGCCCAGCAGGCTGGAGCTGAATCCGGCCCGGAGGAGAACACAAAGTCTGATGAGGAAATGTCCTGCCAAAAGCCAAAGGAACAGGAGCAGTACGAGGAAGGTGAGAACTGTCCAACTTCGCTGCGTCCCAGGGAAACGTCTTCCTCCTGCGATGAGACAAgcgatgcagatgcagatgcggAGGCGGATGCGTGCGTGGCAGGGGAATCATCCATCGCTGGTGTCTCGAATGAAATCCAAGAAGTAGAAGGCAAGGACAAGGATGGCAAGGAGTCCCTAGCCGAATTGGAAACCAGCTGCGAGGGGaagccagaggcagagtcgATCAAGGAGCTGCCGTCCAGAACGGAAAAATCAGCGAGTGATTATTCGGATGAGAGCACCCTTAAaaatgaggaggaggagcaggagcaggaggagacTGCGTCCAAGCAAGAGACAACGTTGAATGGAGAAGTGACGCCCAATCCAGCTGCGATGGAGCTTCAGTCGAAGGAACTGACCTCGTCCACAGAGCtcacagccgcagccgcagccacacccacagccccagccagtgagcaggagcagcagtctCTGGGTGAGGCAGGACAGTTGGAGCAGTCGGAGCAGTCGGAGCAGCCAGAGATTATTGTGAGCATACCTCTCGAGGTACTCAATGAGGATCTGCAGCGCAGACTGTGCGTGGACCAGGGGCACAACAACGAGGGGGAGGATGATCAGGATGAGGGTCAGGATCaggagaagaagcagcagcaggatccCGGCCAGCCCGACGATGTCAACAACAATGCCAATGATGAGAATTTTTGCCAGAGTGCTACAGCAGATAGCTTCAATTCTGCTGTGGCACTCCAAACAAACGAAATTGAAGCAAACACCAGCCGCCCCCCCGATGGGGCACCATCGCCGCCATCGCCAATAGCAACAGGcggggacggggatggggacGAGGACTCCCTCTCGTCCTCAGATGAGGTGCCAGTGGCCAGGACTGGACCCACACCCATGGACTTTCTGGCCGAATTCGAGAAGCATTGCGAGAAGGGTCTCGAGCAGATTGGGGCCACAACACCGGGCCCATCGCCGCCACCCACACCCAAGGCCGAGCCCCTGCCGCTGGCCCTCAACGATGTGGAGGccaagcagcagctggaggtGGAGATGAACGACGTGGAGACCACGCTGAATGGCATCCTCAACGAGATGCAGGACCAGCACATGTACACACCGACCTGTCCGCACATCGACGAGTTCCTCACCCCCGCCGACTATGCCTCCCTCAGCGAACCAGAGCCGGACCAGGAGCCagaccaggagcaggagcaggagccatCCGGCGACTCCAGTCCAGTGGCAGAGAaacggcaggagcaggagaagccAGTGGCCAGCCAGCAGGAGGATCTCTTCGATAACAGCAACTTTAGCAACGAACTGATTGGCTTCCAGAACGATATTCCCTGCTTTGAGAACATCGAGGCCTCGCCAGAGCCCGAGCAGAGTCTGCATCTGGAGCTGACGCAGTTCCTCAACGagctgcagccccagcaggGCCCACAGGCCCCGCAGGTATCGCCTGGGGGTGCtcaggtgcaggtgcaggtgcaggttGCCGTACCTCAAGTTGAGGCAGCCGCAGGAGCAGTCGCAGTCGCGGTCGCCCCTGAGGTGCaggtggagcagcagcctctggtggagcagcagcctcaggtggagcagcagccccagGTGCCTGTTCAAGTTCAGGTGCAACCACAACCTCTCGAGCATCTTCGTGCCCGTCAGCGGCCAATAGTGGCAAAAGCTCTGGAGCAGCCCCAGTTGGTCCAGGTGCCTCAGGTGCATCACCAGGAGACGACAACGACCGTTTCCTACGAGCAGATctatcaccatcatcatcatcatcagcattcTGTCCAGCAGTCGGCCAGCAAGCTGCAACTGATGCCAGTTGCCCCCATCGATccgcagcagcatcagcagcagctgcagctgcagcagcagcatcagcagcatcagcactGGCAGCAGTATCAGccccaggagcagcagcagcagcagcagacgacACATCTGCAATGGTCGGCTGTGGGCGGACTGGAGGCCATCAAGAGCGGCGTTGGTCCATTGGAGAGCACCACAACGTACTACATCAGTGCTGGGGATCTctaccagcaccagcagcaggctGCACCACTGGAGACCACCTACACGATGCTAGATCCCAACGAGAACTACATGCTCGAGCAGGCCAcccagcatcatcatcatcagcagcagcagcagcagcagcagcagctgcagcatcatcagcaacagcaggcactccagcagcagcagcagcaacagcaacaacaacagcaacccATCATGATACTGATCCAGCAGCCGGAACTGCAGCAGCCAGTGGCCTCGGCCAGTAATCCCCAGCAGGCGCCGATGCATTTTTACGGTGCGCCCATCAGCAACGAGTTGCATCatctacagcagcagcaacagcagcagcagcagcaccagcaccagcagcagcagcaacagcatcatcaacagcagcagcatcatcatccacagcagcagcatcaagtACAAAATCATTCAGTATTAGCAGCAGCCTCTCCAATGCCCGCCACCACGCCCAAGGGTCGGGCCGTGTCGCTCAAGTGCCGCTTCTGCCAGAACGGACCGAGATTCAACAACAGCCTGGAGTACAGTCGTCACATCATCGAGCTGCATCCGGCGGTGGCGCCCTTCAACTGCCCGCACTGTCCGCTGGCCTTTGCGGCGCGCAGCAAGCGCTCGCAGCACATCCTCAACCAGCATGTGGTGCAGCAGTATCAGTGCGGCCAGTGCTCGCAGGTCTTTCCCGCCCAGCGAGCCCTCGACTTGCACATTCAGCGCTTCCACATGCAGGTGACCAGCAACACGGGCGGCGCAGAGAAAGGCGCAGGTGTGCGCGTGGAGGAAGTTCAATTGCAGATCAGCAACGAGCATCAGCAGCCGCATCCGTCAGCTCTCGAGCTGCATGGCAACGCGGCAGGACCACGCAGGCAGCGCATTCTCTGCTGCCCGGACTGCGAGGACTGCACCTCTGGCCACAGTCACGGCCATGGACAGTACGAGGAGCTGCAGACGAATCTGCAGACACCGCCAACGGTGCTAACGCCGCCCTCGACGATCATGTCGGTGCCGTCGCCGCAGCCCCTGACGAGCACGCATCAGCACATAACGCTGCCCTCGCCAGAGCAATCGGAGCCGGACTCCACCACGACGCTGCGGCAGTTTCGCAAACGAGGCGTCATTGTGGGCCCACAATCAGCCGGTGGCTTCAATCAGTCACTGCAGCTGGCCACGCCCGTGGCATCGCCCTCACCCTCGCCCTCGTCGTCGCCGTCCTCGTCCACGATAGACTCGGCGCCAAACACGCccgcctcggcctcggcctccGCCTCTGCATCCGCATCCGTGCAGGTCAGCGAACTGAGGGCCAGCCACCAGTGTCTGTACTGCGAGGAGCGTTTCACCAACGACATTGCCCTGCGGAAGCACCACCAGCTGGCCCACGGGGCCCAGACCACGATGCCCTTCGTGTGCACCATCTGCAAGCGGGGCTATCGGATGCGGACGGCCCTGCATCGGCACATGGAGTCGCACGATGTGGAGGGCAGGCCGTACGAGTGCAACCTGTGCCATGTGCGGTTTCCGCGACCCTCGCAGCTGACGCTGCACAAGATCACCGTCCACCTGCTGTCGAAGCCGCACACCTGCGACGAGTGCGGCAAACAATTTGGTACGGAGAGCGCCCTAAAGACGCACGTTAAGTTTCACGGTGAGTTTGGTTACCAGTGCGACGAGTGCGATCAGGTGTTCGAGTATCTGGGAGATTTGCGCAAGCACCGGCGCACCCACAACAGCGAATTGTTTTACAAATGCGAGTTCTGTCCACGCTCCTTCTTGCATTTCATGGGTTTCCGCGCTCACATGAACACCCATCTGCCACTTGGAGTGTTTCTGAACGAGGAGACTGCTTTGAAGTCGTCGTCCAGCTGCAGCatcaccaccagcaccaccagcatcatcagcagcatcagcagcgtACGCAATGACAAGTACAGCGAGAATCCAGCCACACCCATCGTAGAGGAGACGCCGCTGACCCCGATGAGCAGTATCAATAACAATACAGACGAATGTTGTCCCATCTCCGATTCGGCGGAGAGCAGTGCTTTGGTCGGACGCAGCCTCCCAAGCCTAGATTCGATTGTCGCCACAACGCCATAA
Protein Sequence: MMSNKRFPHLFRTQVSRDDGLPQEICRQCMAQFLMVAKFRRKCVRMQQRLQDYAQEISDRQAAREAKRKQKQQQRLELQQEGQTKQKDLKDMDTDANSSDYMHLPETQMERKRRIISESEGESPSTPRPSRPKIVKTEEVLPPPKERRLQLRLRRMRTQSAGASAGDANADEDANADPIVNAEAEEPPRTLADPSSMPWKTKAARKQLSESWSSCSPALSSEMGGRRSTSSETATEHLSDLSVGPLCGFESDSNPSSSSAPTTLKFPRRSPTAVPALRRGRRPRSSPVYMAVKRQRRSLSKKPTAKELAQQAGAESGPEENTKSDEEMSCQKPKEQEQYEEGENCPTSLRPRETSSSCDETSDADADAEADACVAGESSIAGVSNEIQEVEGKDKDGKESLAELETSCEGKPEAESIKELPSRTEKSASDYSDESTLKNEEEEQEQEETASKQETTLNGEVTPNPAAMELQSKELTSSTELTAAAAATPTAPASEQEQQSLGEAGQLEQSEQSEQPEIIVSIPLEVLNEDLQRRLCVDQGHNNEGEDDQDEGQDQEKKQQQDPGQPDDVNNNANDENFCQSATADSFNSAVALQTNEIEANTSRPPDGAPSPPSPIATGGDGDGDEDSLSSSDEVPVARTGPTPMDFLAEFEKHCEKGLEQIGATTPGPSPPPTPKAEPLPLALNDVEAKQQLEVEMNDVETTLNGILNEMQDQHMYTPTCPHIDEFLTPADYASLSEPEPDQEPDQEQEQEPSGDSSPVAEKRQEQEKPVASQQEDLFDNSNFSNELIGFQNDIPCFENIEASPEPEQSLHLELTQFLNELQPQQGPQAPQVSPGGAQVQVQVQVAVPQVEAAAGAVAVAVAPEVQVEQQPLVEQQPQVEQQPQVPVQVQVQPQPLEHLRARQRPIVAKALEQPQLVQVPQVHHQETTTTVSYEQIYHHHHHHQHSVQQSASKLQLMPVAPIDPQQHQQQLQLQQQHQQHQHWQQYQPQEQQQQQQTTHLQWSAVGGLEAIKSGVGPLESTTTYYISAGDLYQHQQQAAPLETTYTMLDPNENYMLEQATQHHHHQQQQQQQQQLQHHQQQQALQQQQQQQQQQQQPIMILIQQPELQQPVASASNPQQAPMHFYGAPISNELHHLQQQQQQQQQHQHQQQQQQHHQQQQHHHPQQQHQVQNHSVLAAASPMPATTPKGRAVSLKCRFCQNGPRFNNSLEYSRHIIELHPAVAPFNCPHCPLAFAARSKRSQHILNQHVVQQYQCGQCSQVFPAQRALDLHIQRFHMQVTSNTGGAEKGAGVRVEEVQLQISNEHQQPHPSALELHGNAAGPRRQRILCCPDCEDCTSGHSHGHGQYEELQTNLQTPPTVLTPPSTIMSVPSPQPLTSTHQHITLPSPEQSEPDSTTTLRQFRKRGVIVGPQSAGGFNQSLQLATPVASPSPSPSSSPSSSTIDSAPNTPASASASASASASVQVSELRASHQCLYCEERFTNDIALRKHHQLAHGAQTTMPFVCTICKRGYRMRTALHRHMESHDVEGRPYECNLCHVRFPRPSQLTLHKITVHLLSKPHTCDECGKQFGTESALKTHVKFHGEFGYQCDECDQVFEYLGDLRKHRRTHNSELFYKCEFCPRSFLHFMGFRAHMNTHLPLGVFLNEETALKSSSSCSITTSTTSIISSISSVRNDKYSENPATPIVEETPLTPMSSINNNTDECCPISDSAESSALVGRSLPSLDSIVATTP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00481187;
90% Identity: -
80% Identity: -