Basic Information

Insect: Drosophila helvetica
Gene Symbol: -
Assembly: GCA_963969585.1
Location: OZ018402.1:8601555-8602927[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.0036 0.34 11.9 7.8 1 23 152 174 152 174 0.98

2 6 1.9e-05 0.0018 19.0 1.3 1 23 180 202 180 202 0.99

3 6 7.2e-06 0.00068 20.4 0.4 1 23 208 230 208 230 0.98

4 6 7.5e-06 0.00071 20.3 0.3 3 23 238 258 236 258 0.97

5 6 0.00013 0.013 16.4 4.4 1 23 264 287 264 287 0.95

6 6 1.7e-07 1.6e-05 25.5 0.4 1 23 323 345 323 345 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.0036	0.34	11.9	7.8	1	23	152	174	152	174	0.98
2	6	1.9e-05	0.0018	19.0	1.3	1	23	180	202	180	202	0.99
3	6	7.2e-06	0.00068	20.4	0.4	1	23	208	230	208	230	0.98
4	6	7.5e-06	0.00071	20.3	0.3	3	23	238	258	236	258	0.97
5	6	0.00013	0.013	16.4	4.4	1	23	264	287	264	287	0.95
6	6	1.7e-07	1.6e-05	25.5	0.4	1	23	323	345	323	345	0.99

Sequence Information

Coding Sequence: ATGGATTACAATATCCACAAAATCTGTCGCGTTTGCCTGGAGGAGGGCACCCCAGGACCCCTGACGTCCATCTACAGCACAGACTTTGCCATGATGCCCTCTGTGATGCTCATGCAGTGCGCCAAGATTCGAGTTTATAAGACAGATGCTTTGCCGTCGGTTATCTGCAATAATTGCATCTACCGTCTGGGAGTAGCTTTCCATTTTAAGCAGCAATGCGAAAACAGCGATCTGAGATTGCGTCAATATTTGGGTGTACTCGAGTCCTGGCGTCAGGATGCAGCCACCAACACGGACTTTGTGGATAAACCCTTGGCCGCGAGTCATATACTGATCTCCAGTGATGAGGAGGAGCCAGCGGACACCAAGACGAGCAAACGACGCTCGCGCTATCAGCGCAAGCCGCCCGAACAGCACAAGAAGCGTGGACCAAAACCCCTGCCCAAGATGCCACACACCTGCTACGAGTGCCACAAGAGCTTCAAGTGCATTGCCCAGCTTACCCAGCACATACGGACGCACACGGGAGAGAAACCGTATCAGTGCGGCTATTGCATCCAGCGATTCGCCCAGAAGTATAATCTGAAGGTGCACGAACGTACCCACACGGGCGACAAGCCCTTCCAATGCGAGATCTGCTCGAAACAGTTCTCAGCGTTGGGCAACTTTCAGGCGCATCAAAAGATCCACGTCGGTGTGAGGGATCAGATCTGCTCTATGTGCCAGAAGGGCTTCTATACGGCCGGTGATCTGTCCAAGCACATGATAACCCACACTGGCATCAAGAATCATCATTGCGATGTTTGTGGCAAGGCCTTCAGTCGGCGACGTGATATGCGATCCCACAAACTGAAGCTCCATCCCTTGGAGTCCAGCACGGTCCACGATATtgtggatgatgatgatgatgagccCATAGACACGGATCCCGTGGGTCTGGATACCCTCGACGATGATCATGCCCATTTCAAGTGTCCCGACTGTGATAAAGCCTTCGATACTGCCGACAGTCTTAGCTTACACTTCCGCACCCATGCGGTGAACAACAACCTCCTGAATTTACCCTTGCCGCCTGCTCCACCCATGTCGCATCACTACCACCACCATCATCCGGCAGGGAGTGCACCGTCCTCGGCAGCCATGCATCATCACGACGCACTGCATCACCTGGGCCCGCCGAATGCAGCCACACAAATGGGAATGGCCGCCATGGCTCACATGCTggcaccgccgccgccgccaccacccaCGCCCAGTGAGGGCCGCTACTCAATGCTCCATCACACGGCGGCCCAAAGGTTGCACTACTAA
Protein Sequence: MDYNIHKICRVCLEEGTPGPLTSIYSTDFAMMPSVMLMQCAKIRVYKTDALPSVICNNCIYRLGVAFHFKQQCENSDLRLRQYLGVLESWRQDAATNTDFVDKPLAASHILISSDEEEPADTKTSKRRSRYQRKPPEQHKKRGPKPLPKMPHTCYECHKSFKCIAQLTQHIRTHTGEKPYQCGYCIQRFAQKYNLKVHERTHTGDKPFQCEICSKQFSALGNFQAHQKIHVGVRDQICSMCQKGFYTAGDLSKHMITHTGIKNHHCDVCGKAFSRRRDMRSHKLKLHPLESSTVHDIVDDDDDEPIDTDPVGLDTLDDDHAHFKCPDCDKAFDTADSLSLHFRTHAVNNNLLNLPLPPAPPMSHHYHHHHPAGSAPSSAAMHHHDALHHLGPPNAATQMGMAAMAHMLAPPPPPPPTPSEGRYSMLHHTAAQRLHY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00612989;
90% Identity: iTF_00515087;
80% Identity: -