Basic Information

Insect: Drosophila helvetica
Gene Symbol: -
Assembly: GCA_963969585.1
Location: OZ018401.1:12897363-12899453[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.035 3.4 8.8 0.1 3 23 290 311 289 311 0.91

2 10 7e-05 0.0067 17.3 0.5 6 23 320 337 320 337 0.99

3 10 1.8e-05 0.0017 19.1 0.3 1 23 343 366 343 366 0.98

4 10 0.00015 0.015 16.2 0.7 1 23 378 400 378 400 0.97

5 10 0.0011 0.1 13.6 7.1 1 23 407 430 407 430 0.96

6 10 3.8e-06 0.00036 21.3 2.4 1 23 436 458 436 458 0.97

7 10 0.07 6.7 7.8 0.7 2 23 467 488 466 488 0.97

8 10 0.00013 0.012 16.4 2.7 3 23 495 516 493 516 0.95

9 10 1.4e-06 0.00013 22.6 1.1 1 23 522 544 522 544 0.98

10 10 0.00019 0.018 15.9 4.4 1 23 550 573 550 573 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.035	3.4	8.8	0.1	3	23	290	311	289	311	0.91
2	10	7e-05	0.0067	17.3	0.5	6	23	320	337	320	337	0.99
3	10	1.8e-05	0.0017	19.1	0.3	1	23	343	366	343	366	0.98
4	10	0.00015	0.015	16.2	0.7	1	23	378	400	378	400	0.97
5	10	0.0011	0.1	13.6	7.1	1	23	407	430	407	430	0.96
6	10	3.8e-06	0.00036	21.3	2.4	1	23	436	458	436	458	0.97
7	10	0.07	6.7	7.8	0.7	2	23	467	488	466	488	0.97
8	10	0.00013	0.012	16.4	2.7	3	23	495	516	493	516	0.95
9	10	1.4e-06	0.00013	22.6	1.1	1	23	522	544	522	544	0.98
10	10	0.00019	0.018	15.9	4.4	1	23	550	573	550	573	0.96

Sequence Information

Coding Sequence: ATGATTTGCAGGCTATGCCTGCGCAGCATAAATCCCAGCAATGCCGTGTTCCTGTTCGAAACGAACGAGACATTGGCGGAGACGACGCTGGTCAAGATGATTGCCAAATTCCTGCAGTTGGAGATCACGCCCGACGACAGCATCTCAACGAGCGTCTGCACCGGGTGCTGTGAGCATCTGGAGGACTTCAACACCTTCTGGCAGCTGGTGGAACAGAAGCAGGGCACGCTCAAAAAGGAGTTCCTCACCGTCGACGTGGACTGCGTGGCGATGAAGTGGACGGGCGAGGTAGATGTGGACGTCAATATTGACGAGCTTCCGCTGGTGGCAGTCGAAATGGACGAGAAGCCCCTCGATATGCACAACCTGCTGGGCAGTGTTCTGGATGTGAATGTGGACAGTGTGGAGGTGCCACAGGTGCCGCTTGGGGATATCAAAATTCAGCCAACTGATTACCTGTCCGAGGAAGACGAGCATCCACCCCATCTCGAGGCGACGGACAGCGAGTTCGAGTGCGAGCCAGTCCCCGAAGAAGACACCTCGGATGATGAGCCGCTGGTCAAGCTGCAGGACAAGTTGAAGCCCAAGCGCAAGTCCCAGCCCCGCACCACAAAGACACGGGAAACCACCTGCTCACTCGCAGCTCAGGAGCTGAATTATCTCCTTGGGCGGGGCGATGGCGACGgcgatggtggtggtggcgagTGCAGCAAAGGGCGTCGCAGAAAGGCGCCTGGCCAGCGCATACCCACGGAGGTGCAGGAGAGCGAGCTGCAGGCAGCGCTCGAGCGCAAGCCCAAGGGCTGTTCGCGAGCCCAGCTGGCCAAGCGGTACGAGGAAGTCATAGCCAGCTACATGAACGCCGACTGCGACCTGTGCGACTATAGCGGCAAGTATCTGTCCGAGCTGAAGGTGCACTTCCTGGAGGCGCACCAGCGGGAGTTCTACATCAAATGCTGCAACAAGGTCTTCACACGCGCCTCCAAGCTGATGGACCACATACGCAAGCATGTCAATCCCAAGCTCTTCACCTGCTCCATCTGCCAGAAGACTCTCAACTCGCAGGACTATCTGGCCACCCACATCGAGACGGTGCACAACAAGGTGGAGAAACTCGACAAGGTGCTGCAGTTCCCCTGCTCCAAGTGCGAGCGCACCTTCAGCAGTGAGCGACGCCTGGCCAACCATCTCGCGAAGCACGACACGGCAACGCTGGAGCACATCTGCCACATATGCCATAAAAACTTTGCCAATGTCCATCGTCTGCGCCGGCACATCCAGTCCATACACGAGGACCTGCACCGACATGTGTGCGACATCTGCGGCAAGAAGTTCAAGTTCAAGCCCTCGTTCGAGCGGCATCTGCGCGAGCATCAGGGCGTGGTGGCACCGGCCATGCAGTGCCCCGTCTGCGGTGTCTGGCTGAAGAACGAGCACAGTCTGCGGCTGCACCGCTTCACCCACGACAGCACCAACACGGCCTGCCCCCACTGCTCGAAGACGTGCAACTCGAGAACAGCGCTGCGCGCCCACATCAAGTATGCCCACAAGCTGACGACCAGCTTCCAGTGCACGTACTGCGAGAAGACCTTCAAACAGCAGCGCAACCTGGACGAGCATCTGGCCATCCACACTGGCCTCCAGCTGTACAACTGTCCGCACTGCCCCAAGGAGTGCCGCTCCCGGTCCAACATGTACGTGCACATCAAGCAGCGGCATGCGGAGGAGTGGCTCACCGCCAAGATGGCCCGCTCCCACAATCCGCAGTTCAAGCCGCACGTCTAA
Protein Sequence: MICRLCLRSINPSNAVFLFETNETLAETTLVKMIAKFLQLEITPDDSISTSVCTGCCEHLEDFNTFWQLVEQKQGTLKKEFLTVDVDCVAMKWTGEVDVDVNIDELPLVAVEMDEKPLDMHNLLGSVLDVNVDSVEVPQVPLGDIKIQPTDYLSEEDEHPPHLEATDSEFECEPVPEEDTSDDEPLVKLQDKLKPKRKSQPRTTKTRETTCSLAAQELNYLLGRGDGDGDGGGGECSKGRRRKAPGQRIPTEVQESELQAALERKPKGCSRAQLAKRYEEVIASYMNADCDLCDYSGKYLSELKVHFLEAHQREFYIKCCNKVFTRASKLMDHIRKHVNPKLFTCSICQKTLNSQDYLATHIETVHNKVEKLDKVLQFPCSKCERTFSSERRLANHLAKHDTATLEHICHICHKNFANVHRLRRHIQSIHEDLHRHVCDICGKKFKFKPSFERHLREHQGVVAPAMQCPVCGVWLKNEHSLRLHRFTHDSTNTACPHCSKTCNSRTALRAHIKYAHKLTTSFQCTYCEKTFKQQRNLDEHLAIHTGLQLYNCPHCPKECRSRSNMYVHIKQRHAEEWLTAKMARSHNPQFKPHV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00474705;
90% Identity: iTF_00580951;
80% Identity: -